Santa Isabel Vacation Packages

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Your Santa Isabel Vacation

Our vacation packages to Santa Isabel give you endless opportunities to immerse yourself in new sights, sounds and sensations. And with all the details taken care of, you'll be free to enjoy your city adventure to the fullest. Make your trip to Santa Isabel even more fun and exciting by including some sightseeing. Plaza Comercial La Cachanilla, City Forest and Zoo and Juventud 2000 Sport Center are among the big attractions worth exploring. A few quick clicks is all it takes to put together the perfect Santa Isabel vacation on Expedia.

Top Santa Isabel Vacation Deals

Price found within the past 48 hours. Click for updated prices.
California Comfort and Suites

California Comfort and Suites

3 out of 5
per person
Sep 22 - Sep 29
found 17 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to Mexicali (MXL)
8.4/10 Very Good! (1,003 reviews)
I hadn’t stayed at this property, the room was clean, food adequate. The coffee bar I would avoid, the staff there are not honest. We won’t return as there are much better options in town.

Reviewed on Aug. 2, 2025

Hotel Araiza Mexicali

Hotel Araiza Mexicali

4 out of 5
per person
Oct 11 - Oct 18
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to Mexicali (MXL)
8.6/10 Excellent! (1,473 reviews)
La regadera no sirve

Reviewed on Aug. 2, 2025

Hotel Lucerna Mexicali

Hotel Lucerna Mexicali

4 out of 5
per person
Sep 22 - Sep 29
found 17 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to Mexicali (MXL)
9.2/10 Wonderful! (1,278 reviews)
Property was quiet, clean, and very beautiful. We stayed in the bungalow suite absolutely stunning.

Reviewed on Jul. 31, 2025

Real Inn Mexicali

Real Inn Mexicali

4 out of 5
Civic Center
per person
Sep 8 - Sep 14
found 8 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to Mexicali (MXL)
8/10 Very Good! (1,388 reviews)
I have been staying at the Hotel, ever, since it was crown, plaza Hotel, and even do Real Inn Took, over they been Turning a great Hotel into and average Hotel!! They took took of the small refrigerator, the free breakfast buffet and got very limited on the service, so yes from now on will look into somewhere else , there is plenty of hotel that offer a great service and free breakfast and a small refrigerator even a total kitchen for the service, maintenance is very poor, so it’s becoming just a big nice average hotel, I’m going again to Mexicali on another week and it’s not my favorite no more, so my suggestions go back to offer the great service that you had once, or people like me won’t come back and spend lots of money on it no more ,, Omar Sáenz

Reviewed on Jul. 28, 2025

Ready to book your vacation to Santa Isabel?

 

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Santa Isabel Hotel Deals

Hotel Lucerna Mexicali

Hotel Lucerna Mexicali

4 out of 5
Boulevard Benito Juarez 2151, Mexicali, BC
Fully refundableReserve now, pay when you stay
The price is CA $123 per night from Aug 10 to Aug 11
CA $123
CA $139 total
Aug 10 - Aug 11
includes taxes & fees
9/10 Wonderful! (1,283 reviews)
"My new to go Hotel, so comfortable, great service"

Reviewed on Jul. 31, 2025

Hotel Lucerna Mexicali
Hotel Araiza Mexicali

Hotel Araiza Mexicali

4 out of 5
Blvd. Benito Juarez 2220, Fracc Jardines Del Valle, Mexicali, BC
Fully refundableReserve now, pay when you stay
The price is CA $132 per night from Aug 3 to Aug 4
CA $132
CA $150 total
Aug 3 - Aug 4
includes taxes & fees
8.4/10 Very Good! (1,506 reviews)
Our go to in Mexicali
"Our stay at Araiza was good, despite a smell in the room that came from the drains and some dust in the room the hotels bar and restaurant made up for it. The breakfast buffet had a lot of variety and was delicious. The bar tender suggested a few drinks that we ended up loving so gets some points ..."

Reviewed on Jul. 30, 2025

Hotel Araiza Mexicali
Real Inn Mexicali

Real Inn Mexicali

4 out of 5
Avenida de Los Heroes 201, Centro Civico, Mexicali, BC
Fully refundableReserve now, pay when you stay
The price is CA $96 per night from Aug 17 to Aug 18
CA $96
CA $109 total
Aug 17 - Aug 18
includes taxes & fees
8/10 Very Good! (1,407 reviews)
"I have been staying at the hotel ever since it was a different chain CROWN PLAZA I think!! , and even do the chain of Real inn took over , but I have notice, they took off the small refrigerator, they took of the free buffet, it needs a lots of maintenance which it doesn’t seem to be done at all ..."

Reviewed on Jul. 28, 2025

Real Inn Mexicali
See all 74 properties in Santa Isabel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Discover the most popular places to visit in Santa Isabel

Hospital de la Familia

Though Hospital de la Familia might be what brings you to town, perhaps you'll have a chance to explore more of Mexicali while you are here.

Hospital de la Familia

Hospital Almater SA de CV

Though Hospital Almater SA de CV might be what brings you to town, perhaps you'll have a chance to explore more of Mexicali while you are here.

Hospital Almater SA de CV

Frequently asked questions

How much does a Santa Isabel vacation package cost?
Offering great value package deals from CA $815 on Expedia, you'll be thrilled with how little a vacation to Santa Isabel costs! Our packages make travel planning easier and your savings go further.
What are the cheapest months to go to Santa Isabel?
January, February and August are the best times to search for cheap Santa Isabel vacation packages. Opting to travel in less busy periods means you can generally find lower prices on flights and hotels.
How many days is enough for Santa Isabel?
Santa Isabel vacations can be as short or long as you like, but to get a real feel for this place, we'd suggest 2 days is about right. This will mean you can visit top sights like Juventud 2000 Sport Centre and City Forest and Zoo and seek out some hidden gems. Don't skip neighbourhoods such as Mediterráneo and Lucerna either. If you're clever with your time, you can even take a day trip from Santa Isabel too.
How to find the best Santa Isabel package deals?
Begin your search for a Santa Isabel package deal by entering your destination and preferred trip dates under our "Packages" tab. Then add a few filters, like "Property type" and "Guest rating," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with big savings. If you don't find the ideal Santa Isabel package deal straight away, just change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Santa Isabel getaway off to a flying start.
Is it cheaper to book a Santa Isabel vacation as a package?
You can enjoy significant savings on your next Santa Isabel getaway by booking a tailored vacation package. Click on the "Package" heading, then select your destination and travel dates to view some great hotel prices and airfares. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Santa Isabel?
Land incredible bargains by booking your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Santa Isabel escape.
How to plan a trip to Santa Isabel?

  1. Choose when to travel: Check your calendar and get your bags packed. Your favourite season and the type of activities available will also help you decide when to visit Santa Isabel.
  2. Set your budget: Factor in expenses such as flights, transportation and food when working out how much to save for your trip to Santa Isabel. Then, pick a hotel that suits your budget, whether that's a low-cost option or a swankier getaway.
  3. Set the duration of your trip: Start by listing all the attractions you'd like to experience in Santa Isabel. Then, estimate how long you'll need for each, along with any travel time.
  4. Bundle your hotel and flights: Epic destination, check. Length of stay, check. All that's left is to pick a Santa Isabel vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.