Title: Book The Best Hotels in Santa Fe for 2026 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Santa Fe](https://expedia.ca/Santa-Fe-Vacation-Rentals.d553248623287535268.Travel-Guide-VacationRentals)[Santa Fe Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Fe.d553248623287535268.Car-Rental-Guide)[Santa Fe Vacation Packages](https://expedia.ca/Santa-Fe.d553248623287535268.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santa Fe - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 25 - Dec 26](https://www.expedia.ca/Hotel-Search?regionId=553248623287535268&startDate=2025-12-25&endDate=2025-12-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 26 - Dec 27](https://www.expedia.ca/Hotel-Search?regionId=553248623287535268&startDate=2025-12-26&endDate=2025-12-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248623287535268&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248623287535268&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Fe-Hotels.d553248623287535268.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Fe-Hotels.d553248623287535268.Travel-Guide-Hotels) ## More cheap stays in Santa Fe ![Hospedaje casa cultural wounaan](https://images.trvl-media.com/lodging/45000000/44970000/44968200/44968162/54c12b87_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hospedaje casa cultural wounaan Panama canal, Puerto lara Darien Santa Fe Darien [Get rates](https://expedia.ca/Hotel-Search?startDate=08%2F01%2F2026&endDate=09%2F01%2F2026&selected=44968162&PinnedHotelID=44968162&HadPinnedHotel=true®ionId=553248623287535268) 7.6/10 Good! (4 reviews) [](https://expedia.ca/Hospedaje-Casa-Cultural-Wounaan.h44968162.Hotel-Information) ## Find out more about Santa Fe ### Top reasons to visit Santa Fe - **Breathtaking Scenery:** Santa Fe boasts stunning landscapes that captivate every visitor, perfect for nature lovers. - **Outdoor Adventures:** Engage in various outdoor activities, making it a fantastic destination for adventure seekers. - **Picturesque Beaches:** Relax on beautiful beaches that provide a serene escape from everyday life. - **Cultural Experience:** Explore the vibrant culture of New Santa Fe, immersing yourself in local traditions. - **Budget-Friendly Accommodation:** Enjoy a range of affordable 2-star hotels, offering comfort and convenience. ### Find great hotels in Santa Fe Experience the charm of Santa Fe, Darién Province, where a variety of budget-friendly hotels await your arrival. Primarily featuring 2-star accommodations, these lodgings are designed for those seeking adventure, nature, and pet-friendly options. Enjoy superior comfort, convenient amenities, and spacious interiors with thoughtful finishes that enhance your stay. Whether you're exploring the lush surroundings or simply relaxing, you'll find the perfect retreat in Santa Fe. - **[Hospedaje casa cultural wounaan:](https://www.expedia.ca/Hospedaje-Casa-Cultural-Wounaan.h44968162.Hotel-Information)** Embrace the spirit of adventure and nature at Hospedaje casa cultural wounaan, an ideal retreat for those seeking an outdoor experience. Nestled in the lush landscape of Santa Fe, this hotel offers a variety of activities such as hiking, canoeing, and fishing. Pet-friendly amenities ensure your furry companions are welcome too, featuring a dog exercise area and waived fees for service animals. Guests can relax in the outdoor entertainment area or stroll along the walkway to water, making every moment a connection to nature. ### Where to stay in Santa Fe Santa Fe, nestled in the Darién Province of Panama, offers a perfect blend of breathtaking scenery and outdoor adventures. Whether you're exploring the lush landscapes or relaxing on picturesque beaches, the charm of this city captivates every visitor. Nearby, discover New Santa Fe's vibrant culture and immerse yourself in the natural beauty of the region. Embrace the spirit of adventure as you explore the stunning surroundings that make Santa Fe a must-visit destination. - **[Meteti:](https://www.expedia.ca/Meteti-Hotels.d3000437845.Travel-Guide-Hotels)** Nestled 25.7km from Santa Fe, Meteti is a quaint village that offers a unique blend of outdoor adventures and stunning scenery. Known for its lush landscapes and proximity to both a national state park and a picturesque bay, Meteti attracts visitors seeking an immersive nature experience. While traveller arrivals are relatively steady throughout the year, the peak seasons in January, April, and June draw those eager to explore the local flora and fauna. The slower months in August and November to December provide a more tranquil visit, perfect for those looking to escape the crowds. - **[Agua Fría:](https://www.expedia.ca/Agua-Fria-Hotels.d829297553955622912.Travel-Guide-Hotels)** Located 19.3km from Santa Fe, Agua Fría is a bustling city that showcases the vibrant culture and traditions of the Darién province. This city experiences a highly seasonal influx of tourists, with peak visits occurring in March and during the holiday months of December to January. Outside of these times, particularly in May, June, and August, you’ll find fewer travellers, allowing for a more local experience. Agua Fría is known for its lively atmosphere, offering a mix of urban conveniences and a taste of Panamanian life, making it an ideal stop for those looking to soak in the local culture. - **[Cucunatí:](https://www.expedia.ca/Cucunati-Hotels.d829297574912471040.Travel-Guide-Hotels)** Just 16.1km from Santa Fe, Cucunatí is a charming city that invites visitors to discover its rich heritage and natural beauty. Although specific travel trends for Cucunatí aren’t detailed, its proximity to Santa Fe makes it an appealing option for day trips. As you explore this area, you'll find opportunities for cultural immersion and adventure, whether it’s visiting local markets or exploring nearby natural landscapes. Cucunatí serves as a great base for those looking to experience the essence of Panama while enjoying the serene environment. ### Things to do in Santa Fe Santa Fe, located in Darién Province, Panama, is an ideal destination for outdoor enthusiasts and beach lovers. Enjoy weekend getaways filled with scenic views, explore the lush surroundings, and experience the thrill of camping under the stars. With its breathtaking landscapes and vibrant nature, Santa Fe offers a perfect escape for those seeking adventure and relaxation in a picturesque setting. ### Booking tips and Expedia advantages for Santa Fe When planning your trip to Santa Fe, Darién Province, consider booking your hotel about a month in advance to secure the best rates, especially on Saturdays, which are the cheapest nights. Use Expedia’s last-minute deals for spontaneous trips and refine your search by budget and location for more savings. For transportation, opt for buses or bicycles to cut costs. Additionally, consider booking a package that combines flights, hotels, and activities for better deals. Exploring free local attractions can also enhance your experience without straining your wallet. - **The best time to book a hotel:** Book your hotel in Santa Fe about 1 month out to secure some of the cheapest prices. If you're the spontaneous type, Expedia's last minute deals and discounts are indicated via the green label below the price. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Santa Fe is Saturday. The most expensive day to stay in Santa Fe is Tuesday. - **Find cheap hotels on Expedia:** Utilize Expedia’s search tool to refine your options based on your budget, desired location, and preferred type of accommodation. To find the best prices and offers, arrange the price filter from lowest to highest. - **Consider bundling your trip:** You can save money by combining your Santa Fe hotel reservation with your flights and activities through an Expedia package. ### Find the best attractions in Santa Fe Santa Fe, located in Darién Province, Panama, offers a fantastic blend of beach, outdoor, and scenic adventures perfect for vacationers. Visitors can explore various points of interest, such as the local visitor centre, while engaging in outdoor activities that provide a family-friendly experience. Whether you're seeking adventure or relaxation, Santa Fe has something to suit every traveller's taste. - **Pirre Station:** Located 27.4km from Santa Fe, this visitor centre offers an outdoor adventure experience with family-friendly activities amidst stunning natural beauty, making it a perfect spot for nature lovers and explorers. ### Best time to go to Santa Fe The best time to visit Santa Fe depends on your weather preferences. The hottest average temperature in Santa Fe is in July, when weather is mostly cloudy and rainfall is moderate rain. The coolest average temperature in Santa Fe is in February and March. March is mostly cloudy. | **![calendar icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly cloudy icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | | --------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------- | --------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------------------- | | January | 78.8°F (26.0°C) | Light Rain | Mostly Cloudy | | February | 78.6°F (25.9°C) | Light Rain | Mostly Cloudy | | March | 78.6°F (25.9°C) | Light Rain | Mostly Cloudy | | April | 79.5°F (26.4°C) | Light Rain | Mostly Cloudy | | May | 80.2°F (26.8°C) | Moderate Rain | Mostly Cloudy | | June | 80.6°F (27.0°C) | Moderate Rain | Mostly Cloudy | | July | 80.8°F (27.1°C) | Moderate Rain | Mostly Cloudy | | August | 80.4°F (26.9°C) | Moderate Rain | Mostly Cloudy | | September | 80.2°F (26.8°C) | Moderate Rain | Mostly Cloudy | | October | 79.3°F (26.3°C) | Moderate Rain | Mostly Cloudy | | November | 79.0°F (26.1°C) | Moderate Rain | Mostly Cloudy | | December | 79.2°F (26.2°C) | Light Rain | Mostly Cloudy | ### The nearest major airports for your trip to Santa Fe To reach Santa Fe in Darién Province, Panama, you can fly into Contadora Island Airport (OTD), which is located approximately 96.6km away. Nearby accommodations include [Mar Y Oro](https://www.expedia.ca/Contadora-Island-Hotels-Mar-Y-Oro.h12018383.Hotel-Information), a 3.5-star hotel just 805m from the airport, offering airport shuttle services upon request and free transportation. [B&B Gerald's](https://www.expedia.ca/Contadora-Island-Hotels-BB-Geralds.h12319406.Hotel-Information), a 3-star bed & breakfast, is conveniently located 161m from OTD, making it easily accessible. [Hotel La Isla](https://www.expedia.ca/Contadora-Island-Hotels-Hotel-La-Isla.h36420441.Hotel-Information), also a 3-star establishment, is situated 161m away as well. Each of these hotels provides convenient access to the airport, ensuring a smooth start to your vacation in Santa Fe. ## Recent reviews of Santa Fe hotels ![Hospedaje casa cultural wounaan](https://images.trvl-media.com/lodging/45000000/44970000/44968200/44968162/54c12b87_y.jpg) ### Hospedaje casa cultural wounaan 4/5 Good Good but they need better communicatiy "We had a great time during our visit. Apart from walking the village there isn’t much to do. We still made the most of our time and made friends with many locals. We did feel a little uncomfortable at the end of our trip as the president was complaining that we had paid in advance and he expected us to pay for the hotel the day before we left. After we sorted everything he said with others and complained that we hadn’t spent enough during our trip. " A verified traveller stayed at Hospedaje casa cultural wounaan Posted 5 months ago [](https://expedia.ca/Hospedaje-Casa-Cultural-Wounaan.h44968162.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa Fe hotel booking with Expedia? ### How much is the nightly rate at a Santa Fe hotel? ## Explore a world of travel with Expedia - Lodging - Packages - Vacation Rentals - [Comarca Guna de Wargandí Hotels ](https://www.expedia.ca/Destinations-In-Comarca-Guna-De-Wargandi.d761871214387781632.Hotel-Destinations) - [Meteti Hotels ](https://www.expedia.ca/Meteti-Hotels.d3000437845.Travel-Guide-Hotels) - [Visit Agua Fría ](https://www.expedia.ca/Agua-Fria.dx829297553955622912) - [Visit Metetí ](https://www.expedia.ca/Meteti.dx829297497563209728) - [Visit Río Congo ](https://www.expedia.ca/Rio-Congo.dx829297566746157056) - [Agua Fría Vacation Rentals ](https://www.expedia.ca/Agua-Fria-Vacation-Rentals.d829297553955622912.Travel-Guide-VacationRentals) - [Metetí Vacation Rentals ](https://www.expedia.ca/Meteti-Vacation-Rentals.d829297497563209728.Travel-Guide-VacationRentals) - [Río Congo Arriba Vacation Rentals ](https://www.expedia.ca/Rio-Congo-Arriba-Vacation-Rentals.d829297558596644864.Travel-Guide-VacationRentals) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app