Santa Ana
Antigua Guatemala
Visit Santa Ana
Things to do
From Antigua: Pacaya Volcano Tour in English/Spanish
CA $32
per adult
88% of travellers recommend
From Antigua: Adventure, 2-Day Hiking to Acatenango Volcano
CA $79
per adult
From Antigua: Pacaya Volcano Trek
CA $33
per adult
90% of travellers recommend
Santa Ana Hotel Deals
Barceló Guatemala City
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
The price is CA $133 per night from Sep 27 to Sep 28
CA $133
CA $162 total
Sep 27 - Sep 28
includes taxes & fees
Book a stay at this luxury hotel in Guatemala City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the pool in our ...
9.2/10 Wonderful! (3,306 reviews)
"Our group of 3 stayed one night on our way to San Pedro La Laguna and Antigua. It was quick on their shuttle from the airport to hotel. Rooms were nice and beds very comfortable. Staff was efficient and friendly. I really enjoyed our breakfast next morning before heading out to explore beautiful ..."
Reviewed on Sep 20, 2026
Hotel Museo Spa Casa Santo Domingo
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
The price is CA $333 per night from Sep 23 to Sep 24
CA $333
CA $423 total
Sep 23 - Sep 24
includes taxes & fees
Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the ...
Wyndham Garden Guatemala City
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
The price is CA $152 per night from Oct 3 to Oct 4
CA $152
CA $186 total
Oct 3 - Oct 4
includes taxes & fees
Book a stay at this business-friendly hotel in Guatemala City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
Hotel Camino Real Antigua
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
The price is CA $264 per night from Sep 21 to Sep 22
CA $264
CA $357 total
Sep 21 - Sep 22
includes taxes & fees
Book a stay at this spa hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property ...
9.6/10 Exceptional! (1,008 reviews)
"Very clean room staff was very helpful with accommodations and I would come back again"
Reviewed on Sep 19, 2026
Adriatika Hotel & Residence
4 av 20-44 Zona 14 Guatemala City Guatemala
The price is CA $156 per night from Oct 21 to Oct 22
CA $156
CA $195 total
Oct 21 - Oct 22
includes taxes & fees
Book a stay at this luxury hotel in Guatemala City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
Tikal Futura Hotel & Convention Center
Calzada Roosevelt 22-43 Guatemala City Guatemala
The price is CA $160 per night from Oct 4 to Oct 5
CA $160
CA $195 total
Oct 4 - Oct 5
includes taxes & fees
Book a stay at this luxury hotel in Guatemala City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,002 reviews)
"Tikal Futura has a great location, near Miraflores mall, with a good restaurant on site, and helpful, professional staff. Some rooms have a wonderful view, some can be a bit noisy, but overall, it's my favorite hotel in Guatemala City. It is showing a bit of age, as the flooring in some rooms is ..."
Reviewed on Sep 19, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santa Ana
Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.
Historic Center
While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch.
Barrio de La Concepción
While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.
