Hotels in Santa Ana, Antigua Guatemala

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Our top choices for Santa Ana hotels

Villas Santa Ana-Ricardo

Villas Santa Ana-Ricardo
3.5 star property
Santa Ana
8.8 out of 10, Excellent, (15 reviews)
"Space was clean and had a cozy vibe."
United States
Evelin
The price is CA $162
CA $201 total
includes taxes & fees
Apr 27 - Apr 28
Villas Santa Ana-Ricardo

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana
8.6 out of 10, Excellent, (23 reviews)
"A little too far from everything but as long as you have a car is ok plenty of parking there"
United States
Gustavo
The price is CA $65
CA $79 total
includes taxes & fees
Apr 23 - Apr 24
Hostal Casa Buho

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana
9.2 out of 10, Wonderful, (51 reviews)
"Beautiful hotel with clean rooms and friendly staff. The only downsides are the distance to the center (a 30-minute walk) and the chickens and peacocks screaming early in the morning"
United States
Patrick
The price is CA $91
CA $111 total
includes taxes & fees
Apr 23 - Apr 24
Casa Buho B&B

Castillo De Los Gigantes

Castillo De Los Gigantes
2.0 star property
Santa Ana
The price is CA $20
CA $42 total
includes taxes & fees
Apr 10 - Apr 11
Castillo De Los Gigantes

Kawilal Hotel

Kawilal Hotel
3.5 star property
13.9 km from Santa Ana
9.0 out of 10, Wonderful, (138 reviews)
"The property is absolutely gorgeous and the staff is wonderful. On site restaurant is small but a decent amount to select from to eat. Rooms are clean and comfortable. "
United States
Rochelle
The price is CA $187
CA $228 total
includes taxes & fees
Apr 27 - Apr 28
Kawilal Hotel

Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center
4.5 star property
20.1 km from Santa Ana
9.2 out of 10, Wonderful, (1,010 reviews)
"The room was very nice and clean, very goods staff "
United States
Benigno
The price is CA $151
CA $184 total
includes taxes & fees
Apr 19 - Apr 20
Tikal Futura Hotel & Convention Center

Le Suisse Spa

Le Suisse Spa
3.0 star property
6.8 km from Santa Ana
8.2 out of 10, Very good, (25 reviews)
"Temperatures of pools and spa was wonderful! Staff was very friendly. I enjoyed the food at the restaurant. The tortilla soup was especially delicious. Also had a Michelada that was one of the best I’ve ever had! "
United States
Karen
The price is CA $118
CA $146 total
includes taxes & fees
Apr 10 - Apr 11
Le Suisse Spa

Barceló Guatemala City

Barceló Guatemala City
4.5 star property
22.7 km from Santa Ana
9.2 out of 10, Wonderful, (3,278 reviews)
"Wonderful breakfast buffet."
United States
MARIA
The price is CA $159
CA $194 total
includes taxes & fees
May 1 - May 2
Barceló Guatemala City

Mestizo Cortijo

Mestizo Cortijo
3.0 star property
4.3 km from Santa Ana
8.8 out of 10, Excellent, (125 reviews)
"Friendly staff, beautiful room, great location!"
United States
David
The price is CA $165
CA $201 total
includes taxes & fees
May 4 - May 5
Mestizo Cortijo

Hostal Donde Regina

Hostal Donde Regina
3.0 star property
21 km from Santa Ana
9.0 out of 10, Wonderful, (187 reviews)
"Easy checkin, clean room, hot shower, pizza for dinner! "
Canada
Stephanie
The price is CA $69
CA $84 total
includes taxes & fees
Apr 13 - Apr 14
Hostal Donde Regina

Casa Aurora

Casa Aurora
3.0 star property
20.9 km from Santa Ana
8.8 out of 10, Excellent, (171 reviews)
"Close to the airport and clean roomand staff are very friendly ."
United States
Darren
The price is CA $76
CA $93 total
includes taxes & fees
Apr 21 - Apr 22
Casa Aurora

Hotel y Restaurante Vista Verde

Hotel y Restaurante Vista Verde
3.0 star property
5.9 km from Santa Ana
9.2 out of 10, Wonderful, (10 reviews)
"Great room (#3) with high quality mattress, nice towels and pretty bathroom, lacks some toiletries, quiete place with awesome graden views, property rune by their owners, highly recommended! "
United States
Sergio
The price is CA $92
CA $114 total
includes taxes & fees
May 8 - May 9
Hotel y Restaurante Vista Verde

Hotel Vista Quince

Hotel Vista Quince
5.0 star property
25.5 km from Santa Ana
8.6 out of 10, Excellent, (253 reviews)
"Staff very pleasant and service oriented "
Canada
osbin
The price is CA $174
CA $213 total
includes taxes & fees
Apr 10 - Apr 11
Hotel Vista Quince

L Aurora Inn

L Aurora Inn
3.0 star property
21 km from Santa Ana
8.8 out of 10, Excellent, (127 reviews)
"Comfortable room, very close to the airport, and a nice breakfast"
United Kingdom
ANITA
The price is CA $113
CA $138 total
includes taxes & fees
Apr 12 - Apr 13
L Aurora Inn

Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo
4.5 star property
Barrio de La Concepción, 1.1 km from Santa Ana
9.2 out of 10, Wonderful, (1,046 reviews)
"Gorgeous hotel, clean room, friendly, helpful staff fascinating museum."
United States
Melissa
The price is CA $349
CA $443 total
includes taxes & fees
Apr 13 - Apr 14
Hotel Museo Spa Casa Santo Domingo

Hilton Guatemala City

Hilton Guatemala City
4.5 star property
25.9 km from Santa Ana
8.6 out of 10, Excellent, (706 reviews)
"Yes room very clean … ornate decor…. Bed comfortable and spacious… staff helpful and courteous."
United States
karen
The price is CA $140
CA $171 total
includes taxes & fees
May 1 - May 2
Hilton Guatemala City

Good Hotel Guatemala City

Good Hotel Guatemala City
3.0 star property
23.9 km from Santa Ana
9.4 out of 10, Exceptional, (316 reviews)
"Modern rooms, very clean and very friendly staff "
Germany
Julia
The price is CA $148
CA $180 total
includes taxes & fees
May 1 - May 2
Good Hotel Guatemala City

Apartamento Narama zona 13

Apartamento Narama zona 13
4.0 star property
21.8 km from Santa Ana
10.0 out of 10, Exceptional, (31 reviews)
"Near the mall and restaurants. Host is super reachable, very nice!"
United States
Shawna
The price is CA $104
CA $129 total
includes taxes & fees
Apr 10 - Apr 11
Apartamento Narama zona 13

AC Hotel by Marriott Guatemala City

AC Hotel by Marriott Guatemala City
4.0 star property
26.4 km from Santa Ana
8.6 out of 10, Excellent, (1,002 reviews)
"Convenient Great location Great for business travel "
United States
Patricia
The price is CA $152
CA $185 total
includes taxes & fees
May 3 - May 4
AC Hotel by Marriott Guatemala City

Hotel Don Felipe Airport

Hotel Don Felipe Airport
2.0 star property
20.8 km from Santa Ana
8.4 out of 10, Very good, (43 reviews)
"Had a great experience, staff was top notch, accommodating, and the lovely lady who works the evening shift deserves a huge raise!"
United States
Laura
The price is CA $43
CA $53 total
includes taxes & fees
Apr 16 - Apr 17
Hotel Don Felipe Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Historic Center

While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What are the best hotels in Santa Ana that travellers recommend?
For a highly-rated hotel in Santa Ana, consider the Casa Buho B&B.

This 3-star bed and breakfast has an excellent 9.2 rating. Guests frequently mention the kind staff and appreciate the amenities such as a kitchen, a balcony, and the convenience of free and secured self-parking. The Casa Buho B&B also offers charming mountain views. It is conveniently located near several points of interest, including the Jade Maya Factory and Museum, just 1.2 kilometres away, and the Casa Santo Domingo Museum, which is 1.3 kilometres from the property.
What are the best budget hotels in Santa Ana?
For excellent budget-friendly hotels in Santa Ana, consider Casa Buho B&B and Hostal Casa Buho.

The 3-star Casa Buho B&B, with an impressive 9.2 rating, offers free WiFi, complimentary toiletries, and free self-parking. Guests can enjoy a kitchen for self-catering and rooms with mountain views. It is conveniently located near several attractions, including Iglesia de la Escuela de Cristo (0.8 km) and Museo del Hermano Pedro (1.2 km). Guests frequently highlight the kind staff.

Another great option is the 3-star Hostal Casa Buho, rated 8.6. This hotel also provides free WiFi, complimentary toiletries, and free self-parking. It features a kitchen and rooms that offer mountain views and a mountain site location. Similar to Casa Buho B&B, it is close to many points of interest, such as Iglesia de la Escuela de Cristo (0.8 km) and Museo del Hermano Pedro (1.2 km).
What are the most romantic hotels in Santa Ana for couples?
For a romantic stay in Santa Ana, couples should consider Casa Buho B&B or Hostal Casa Buho.

The 3-star Casa Buho B&B, with a high rating of 9.2, offers a lovely setting with mountain views and complimentary WiFi. Guests frequently mention the kind staff and appreciate the convenience of a kitchen and free self-parking. It is also well-located, being just 1.4 km from the Palace of the Captains-General and 1.3 km from the Casa Santo Domingo Museum.

Another excellent option is the 3-star Hostal Casa Buho, rated 8.6. This hotel also boasts impressive mountain views and provides a kitchen, free WiFi, and complimentary self-parking. It shares a similar convenient location, being 1.4 km from the Palace of the Captains-General and 1.3 km from the Casa Santo Domingo Museum.
What are the best hotels in Santa Ana near Casa Santo Domingo Museum?
For excellent hotels near Casa Santo Domingo Museum in Santa Ana, you should consider Casa Buho B&B and Hostal Casa Buho.

The 3-star Casa Buho B&B, with a superb rating of 9.2, is located just 1.3 km from the Casa Santo Domingo Museum. Guests frequently highlight the kind staff, and the accommodation offers conveniences such as a kitchen, free WiFi, and complimentary self-parking. Many rooms also provide pleasant mountain views.

Another great option is the 3-star Hostal Casa Buho, rated 8.6, which is also 1.3 km from the Casa Santo Domingo Museum. This hostal provides a kitchen, free WiFi, and free self-parking. Guests can enjoy mountain views and a site location located in the mountains.
When is the best time to go to Santa Ana?
The best time to visit Santa Ana, Sacatepéquez, Guatemala, is during the dry season, which runs from November to April.

This period offers consistently pleasant weather, with clear skies and comfortable temperatures, typically ranging from 18°C to 28°C. This makes it ideal for exploring the natural beauty and outdoor activities the region offers, such as visiting Finca El Pilar or hiking Pacaya Volcano. You'll find it easier to get around, as roads are in better condition and there's less chance of rain interrupting your plans.

For couples looking for a relaxed yet active getaway, the dry season is perfect. You can enjoy strolls through the coffee plantations, take scenic hikes without worrying about muddy trails, and dine al fresco in the evenings. The consistent sunshine makes for excellent photography opportunities, capturing the lush landscapes and charming local architecture.

Travellers interested in cultural experiences will also find the dry season suitable. Many local festivals and events take place during these months, and the dry weather ensures comfortable conditions for attending market days or exploring historical sites like the ruins of Antigua, which is a short drive away.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Santa Ana hotel for you.
How can I save on a Santa Ana hotel booking with Expedia?
With Expedia, you'll unlock our lowest prices by becoming a member. It's free and easy to join, and you can even access member perks too. Just remember to sign in to get our best prices on Santa Ana hotels. Another way to save is by booking your hotel and flights together on Expedia, where bundling can lead to significant savings.
How much is the nightly rate at a Santa Ana hotel?
Hotel prices in Santa Ana often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.