Title: 10 Best Hotels in Santa Ana, Antigua Guatemala for 2026 | Expedia.ca

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![Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.](https://images.trvl-media.com/place/553248635975847775/dbfc8e66-dcda-4ff9-9ea4-b39c7cec35ab.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/553248635975847775/dbfc8e66-dcda-4ff9-9ea4-b39c7cec35ab.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

Tonight

[Feb 4 - Feb 5](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2026-02-04&endDate=2026-02-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Santa Ana hotels

![Front of property](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/5ec870c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/2499f453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/1914e3c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Balcony view](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/6642638c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Buho B&B

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Casa-Buho-BB.h91818768.Hotel-Information)

Santa Ana

9.2/10

Wonderful

(49 reviews)

"Great place !!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Abner Israel Polanco

CA $90

CA $109 total

includes taxes & fees

Feb 20 - Feb 21

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Casa-Buho-BB.h91818768.Hotel-Information)

![Garden view](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/4afb3fa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Single Room, 1 Single Bed (Buho 3)](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/2ee1db3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Twin Room, Balcony, City View](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/f4dd18dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/1a5632cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hostal Casa Buho

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hostal-Casa-Buho.h91818295.Hotel-Information)

Santa Ana

8.6/10

Excellent

(22 reviews)

"A little too far from everything but as long as you have a car is ok plenty of parking there"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gustavo

CA $59

CA $74 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hostal-Casa-Buho.h91818295.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/7941cd12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food court](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/ccc0a892.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/ba9c9f7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Villa, 4 Bedrooms | Terrace/patio](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/39c1518b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villas Santa Ana-Ricardo

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Villas-Santa-Ana-Ricardo.h36156032.Hotel-Information)

Santa Ana

8.6/10

Excellent

(12 reviews)

"Space was clean and had a cozy vibe."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Evelin

CA $175

CA $213 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Villas-Santa-Ana-Ricardo.h36156032.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/123000000/122970000/122962400/122962301/4109fa55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Suite, Garden View](https://images.trvl-media.com/lodging/123000000/122970000/122962400/122962301/a6beb5ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/123000000/122970000/122962400/122962301/8827643d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/123000000/122970000/122962400/122962301/6208102c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel y Restaurante Vista Verde

[](https://www.expedia.ca/Santa-Lucia-Milpas-Altas-Hotels-Hotel-Y-Restaurante-Vista-Verde.h122962301.Hotel-Information)

5.9 km from Santa Ana

10/10

Exceptional

(3 reviews)

"Great room (#3) with high quality mattress, nice towels and pretty bathroom, lacks some toiletries, quiete place with awesome graden views, property rune by their owners, highly recommended! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sergio

CA $83

CA $103 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Santa-Lucia-Milpas-Altas-Hotels-Hotel-Y-Restaurante-Vista-Verde.h122962301.Hotel-Information)

![Banquet hall](https://images.trvl-media.com/lodging/8000000/7370000/7363500/7363445/3066689a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/8000000/7370000/7363500/7363445/25397b1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/8000000/7370000/7363500/7363445/9cf24669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7370000/7363500/7363445/bcf9fbce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pensativo House Hotel

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Pensativo-House-Hotel.h7363445.Hotel-Information)

1 km from Santa Ana

9.4/10

Exceptional

(394 reviews)

"Rooms were clean and bed and pillows were comfortable with good A/C. Staff was very helpful and were always ready to assist. Food was excellent. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carlos Alvarez

CA $248

CA $316 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Pensativo-House-Hotel.h7363445.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/4000000/3340000/3333400/3333323/5b698a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/4000000/3340000/3333400/3333323/4fe76cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/4000000/3340000/3333400/3333323/1bf4b2fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3340000/3333400/3333323/24d2ee6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Posada del Angel

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Posada-Del-Angel.h3333323.Hotel-Information)

1 km from Santa Ana

9.6/10

Exceptional

(285 reviews)

"We had a great stay! The hotel is a very charming boutique hotel nestled in Antigua. The room was very comfortable and we were able to rest very well. The staff was always very helpful and friendly. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janelle

CA $338

CA $414 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Posada-Del-Angel.h3333323.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/7000000/6490000/6485600/6485536/cf7cd5b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Master suite 5 | Living area](https://images.trvl-media.com/lodging/7000000/6490000/6485600/6485536/307ea616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/7000000/6490000/6485600/6485536/2321d539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/7000000/6490000/6485600/6485536/0831d2e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Meson Panza Verde

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Meson-Panza-Verde.h6485536.Hotel-Information)

1.1 km from Santa Ana

9.2/10

Wonderful

(445 reviews)

"This was the most amazing hotel we stayed in Antigua! Absolutely beautiful and comfortable! Staff was always very friendly and helpful. Restaurant had amazing atmosphere and food. Will definitely be returning! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janelle

CA $255

CA $312 total

includes taxes & fees

Mar 3 - Mar 4

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Meson-Panza-Verde.h6485536.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/118000000/117840000/117834100/117834041/ec7c37d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Blackout drapes, free WiFi](https://images.trvl-media.com/lodging/118000000/117840000/117834100/117834041/94f08eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Blackout drapes, free WiFi](https://images.trvl-media.com/lodging/118000000/117840000/117834100/117834041/52cdd04e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/118000000/117840000/117834100/117834041/bb9a73a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### EL TEJAR HOSTAL 

[](https://www.expedia.ca/Guatemala-City-Hotels-EL-TEJAR-HOSTAL.h117834041.Hotel-Information)

21 km from Santa Ana

8.0/10

Very good

(17 reviews)

"Staff very friendly and helpful. Room clean and quiet. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

ILEANA

CA $58

CA $70 total

includes taxes & fees

Feb 5 - Feb 6

[](https://www.expedia.ca/Guatemala-City-Hotels-EL-TEJAR-HOSTAL.h117834041.Hotel-Information)

![Rooftop terrace](https://images.trvl-media.com/lodging/36000000/35290000/35287800/35287780/d3874222.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/36000000/35290000/35287800/35287780/0b1ab1c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/36000000/35290000/35287800/35287780/075994b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/36000000/35290000/35287800/35287780/6c24b7a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Las Cruces Boutique Hotel

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Las-Cruces-Boutique-Hotel.h35287780.Hotel-Information)

Historic Center, 1.4 km from Santa Ana

9.8/10

Exceptional

(230 reviews)

"Lovely place with exceptional service "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Juan Carlos

CA $276

CA $337 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Las-Cruces-Boutique-Hotel.h35287780.Hotel-Information)

![Hallway](https://images.trvl-media.com/lodging/2000000/1350000/1347700/1347679/54a057a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food court](https://images.trvl-media.com/lodging/2000000/1350000/1347700/1347679/a3be60c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, Garden View](https://images.trvl-media.com/lodging/2000000/1350000/1347700/1347679/b48e2442.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Ballroom](https://images.trvl-media.com/lodging/2000000/1350000/1347700/1347679/5191cfdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Las Farolas

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Las-Farolas.h1347679.Hotel-Information)

1.2 km from Santa Ana

9.2/10

Wonderful

(715 reviews)

"The property is a very good choice for Antigua. Not 1 complaint. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Blonde

CA $140

CA $171 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Las-Farolas.h1347679.Hotel-Information)

![Breakfast and lunch served](https://images.trvl-media.com/lodging/6000000/5350000/5342800/5342769/dd8efa7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/6000000/5350000/5342800/5342769/a4d0e3bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/6000000/5350000/5342800/5342769/028c8647.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/6000000/5350000/5342800/5342769/2de05618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Dai Nonni Hotel

[](https://www.expedia.ca/Guatemala-City-Hotels-Dai-Nonni-Hotel.h5342769.Hotel-Information)

22.4 km from Santa Ana

9.2/10

Wonderful

(346 reviews)

"Hotel is clean quiet and the staff was awesome I recommend this place breakfast was also really good "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Juan

CA $85

CA $103 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Guatemala-City-Hotels-Dai-Nonni-Hotel.h5342769.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/4000000/3430000/3430000/3429972/c2af4620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/4000000/3430000/3430000/3429972/7f330174.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/4000000/3430000/3430000/3429972/60bdfba6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/4000000/3430000/3430000/3429972/a08b69c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Las Marías

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Las-Marias.h3429972.Hotel-Information)

1.9 km from Santa Ana

9.2/10

Wonderful

(435 reviews)

"clean room in a good area"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

roghayeh

CA $121

CA $148 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Las-Marias.h3429972.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/11000000/10250000/10247600/10247555/c2a818d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/11000000/10250000/10247600/10247555/5ee1a697.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Suite](https://images.trvl-media.com/lodging/11000000/10250000/10247600/10247555/9268b1b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/11000000/10250000/10247600/10247555/898e4a3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ciel-Luxe Hotels

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Los-Olivos-Hotel-Boutique-Y-Restaurante.h10247555.Hotel-Information)

Historic Center, 1.4 km from Santa Ana

8.8/10

Excellent

(371 reviews)

"Friendly and accomadating staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kaushal

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Los-Olivos-Hotel-Boutique-Y-Restaurante.h10247555.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/28000000/27320000/27313900/27313886/f6de29b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/28000000/27320000/27313900/27313886/2ac3c24b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/28000000/27320000/27313900/27313886/ae0ee57d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![20 bedrooms, premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/28000000/27320000/27313900/27313886/a527732e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Suites Terraza Imperial

[](https://www.expedia.ca/Guatemala-City-Hotels-Suites-Terraza-Imperial.h27313886.Hotel-Information)

22.5 km from Santa Ana

9.0/10

Wonderful

(305 reviews)

"Nice clean space with fictional kitchenette."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rochelle

CA $105

CA $136 total

includes taxes & fees

Feb 5 - Feb 6

[](https://www.expedia.ca/Guatemala-City-Hotels-Suites-Terraza-Imperial.h27313886.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/7000000/6490000/6485600/6485588/0a0a0571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/7000000/6490000/6485600/6485588/64e07485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/7000000/6490000/6485600/6485588/0c9b5ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![7 Suite Santa Rosa](https://images.trvl-media.com/lodging/7000000/6490000/6485600/6485588/1904b3c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Rafael Hotel

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-San-Rafael-Hotel.h6485588.Hotel-Information)

Historic Center, 1.5 km from Santa Ana

9.8/10

Exceptional

(447 reviews)

"Great room"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Steven

CA $261

CA $329 total

includes taxes & fees

Mar 4 - Mar 5

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-San-Rafael-Hotel.h6485588.Hotel-Information)

![Garden](https://images.trvl-media.com/lodging/69000000/68060000/68050700/68050617/bb83e52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Quadruple Room, 2 Double Beds](https://images.trvl-media.com/lodging/69000000/68060000/68050700/68050617/db50fe14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily full breakfast (USD 10 per person)](https://images.trvl-media.com/lodging/69000000/68060000/68050700/68050617/9e6e7dda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/69000000/68060000/68050700/68050617/2838d7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Cacique Real

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Cacique-Real.h68050617.Hotel-Information)

1.8 km from Santa Ana

8.8/10

Excellent

(167 reviews)

"A beautiful hotel that’s in a nice location that isn’t far from all the main tourist attractions but is also slightly calmer than the main high streets. The staff were all really helpful and friendly and the breakfast was great."

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Magdalene

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Cacique-Real.h68050617.Hotel-Information)

![Economy Room](https://images.trvl-media.com/lodging/101000000/100930000/100929200/100929168/3a512317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Traditional Room](https://images.trvl-media.com/lodging/101000000/100930000/100929200/100929168/bf607aa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Room](https://images.trvl-media.com/lodging/101000000/100930000/100929200/100929168/1298574a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100930000/100929200/100929168/9713294c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa 96

[](https://www.expedia.ca/Guatemala-City-Hotels-Casa-96.h100929168.Hotel-Information)

20.9 km from Santa Ana

9.0/10

Wonderful

(350 reviews)

"Easy to find, close to the airport, clean and friendly staff; exactly what I needed for one night."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Miguel

CA $70

CA $86 total

includes taxes & fees

Mar 7 - Mar 8

[](https://www.expedia.ca/Guatemala-City-Hotels-Casa-96.h100929168.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/13000000/12850000/12847300/12847243/84429269.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/13000000/12850000/12847300/12847243/bc0624c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/13000000/12850000/12847300/12847243/26bad946.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/13000000/12850000/12847300/12847243/3b89d44e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Naif Boutique Hotel

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Naif-Boutique-Hotel-Gallery.h12847243.Hotel-Information)

Historic Center, 1.4 km from Santa Ana

9.0/10

Wonderful

(394 reviews)

"We had a great stay! Very comfortable and nice."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janelle

CA $118

CA $144 total

includes taxes & fees

Feb 12 - Feb 13

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Naif-Boutique-Hotel-Gallery.h12847243.Hotel-Information)

![Classic Quadruple Room, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/25000000/24730000/24724000/24723942/7d503cbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/25000000/24730000/24724000/24723942/1cd00077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/25000000/24730000/24724000/24723942/ae6bb8fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Room, Multiple Beds, Non Smoking | Terrace/patio](https://images.trvl-media.com/lodging/25000000/24730000/24724000/24723942/42653f3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aurora Express

[](https://www.expedia.ca/Guatemala-City-Hotels-Aurora-Express.h24723942.Hotel-Information)

20.7 km from Santa Ana

9.0/10

Wonderful

(618 reviews)

"Verry clean rooms and nice building! Staff were verry helpfull as well"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Zach

CA $71

CA $87 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Guatemala-City-Hotels-Aurora-Express.h24723942.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/4000000/3580000/3575400/3575304/5f9e57fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, down comforters, Tempur-Pedic beds](https://images.trvl-media.com/lodging/4000000/3580000/3575400/3575304/4bf77fc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite | Living area](https://images.trvl-media.com/lodging/4000000/3580000/3575400/3575304/04c9e90c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/4000000/3580000/3575400/3575304/b18ccd3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Santa Rosa Hotel Boutique

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Casa-Santa-Rosa-Hotel-Boutique.h3575304.Hotel-Information)

Historic Center, 1.4 km from Santa Ana

9.6/10

Exceptional

(335 reviews)

"Best place to stay in Antigua!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maria

CA $190

CA $232 total

includes taxes & fees

Feb 11 - Feb 12

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Casa-Santa-Rosa-Hotel-Boutique.h3575304.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-15&endDate=2026-02-19&regionId=553248635975847775&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. 

- Historic Center
- Barrio de La Concepción

![](https://mediaim.expedia.com/destination/1/74ddc5a8bc392ba990ada31c1bf76007.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/bd4f4cf2ac6696e4d9dd7a1c5261170e.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/b494c5622ebb15c1dd7e91ce76ce75f2.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/3d9e1f30df3a11ff4ad43007765de7e3.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/b2651b17b5e3f38b232fea61824aba4c.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=911355684795535360)

![Historic Center map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:o%7EzwAthyhPXoK_%40%7Di%40ri%40a%40j%40fv%40yj%40f%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=r_Zy9R--c8e6nlgWjV2_dDRw1Is=)

### Historic Center

While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=911355684795535360)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=911356092010033152)

![Barrio de La Concepción map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mqzwAlqwhPIwL%60E%7DHfFdBW%60SgKL&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Z_eq5PTC3hcK7WdhMP04Ad5umoE=)

### Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=911356092010033152)

## Top Santa Ana Hotel Reviews

![Hotel Biltmore Guatemala](https://images.trvl-media.com/lodging/2000000/1400000/1397600/1397563/1b77a837_y.jpg)

### Hotel Biltmore Guatemala

10/10 Excellent

"Very helpful staff. Room was bright and clean"

[](https://expedia.ca/Guatemala-City-Hotels-Hotel-Biltmore-Guatemala.h1397563.Hotel-Information)

![Hotel Museo Spa Casa Santo Domingo](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/20929971_y.jpg)

### Hotel Museo Spa Casa Santo Domingo

10/10 Excellent

"From the moment I stepped into Casa Santo Domingo, I felt like I had entered another world. This place is not just a museum — it’s an experience that wraps you in history, beauty, and tranquility all at once. Walking through the ancient stone corridors and peaceful courtyards, I could feel the soul of Antigua all around me. Every corner tells a story, and every detail feels thoughtfully preserved and lovingly presented. The museum exhibits are fascinating and diverse, blending colonial art, archaeological treasures, and contemporary pieces in a way that feels natural and inspiring. I loved how the ruins themselves are part of the display — it makes the history feel alive rather than distant. The gardens are breathtaking, perfect for slowing down, reflecting, and simply soaking in the atmosphere. It’s one of those rare places where you don’t feel rushed; instead, you’re invited to wander and truly connect. What made my visit especially memorable was the sense of calm and wonder I felt throughout the entire experience. Casa Santo Domingo manages to be grand yet intimate, educational yet deeply emotional. I left feeling inspired, grateful, and completely in love with Guatemala’s rich cultural heritage. This is a must-visit in Antigua — a place I would happily return to again and again. "

[](https://expedia.ca/Antigua-Guatemala-Hotels-Hotel-Museo-Spa-Casa-Santo-Domingo.h1246555.Hotel-Information)

![The Westin Camino Real, Guatemala](https://images.trvl-media.com/lodging/1000000/180000/174100/174075/37599208_y.jpg)

### The Westin Camino Real, Guatemala

10/10 Excellent

"Great staff and room service "

[](https://expedia.ca/Guatemala-City-Hotels-The-Westin-Camino-Real.h174075.Hotel-Information)

![Hyatt Centric Guatemala City](https://images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/b1a04679_y.jpg)

### Hyatt Centric Guatemala City

10/10 Excellent

"Excellent location, Cortes’s staff, beautiful installations, good wifi, shower, gym, just an excellent combination for an enjoyable stay."

[](https://expedia.ca/Guatemala-City-Hotels-Hyatt-Centric-Guatemala-City.h19317570.Hotel-Information)

![Hotel Camino Real Antigua](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/17346378_y.jpg)

### Hotel Camino Real Antigua

10/10 Excellent

"What an amazing hotel, we just loved everything about our stay."

[](https://expedia.ca/Antigua-Guatemala-Hotels-Hotel-Camino-Real-Antigua.h3084914.Hotel-Information)

![Hotel Casa Carmina   ](https://images.trvl-media.com/lodging/112000000/111140000/111131100/111131046/1a3fcc86_y.jpg)

### Hotel Casa Carmina 

10/10 Excellent

"Great location near a lot of good restaurants "

[](https://expedia.ca/Antigua-Guatemala-Hotels-Hotel-Casa-Carmina.h111131046.Hotel-Information)

![Clarion Suites Guatemala City](https://images.trvl-media.com/lodging/1000000/30000/27900/27811/e487f2b2_y.jpg)

### Clarion Suites Guatemala City

10/10 Excellent

"Friendly, informative and professional staff, excellent food, very clean room. Food in the restaurant, excellent, we had to wait a little longer though but overall we’re happy with our stay at Clarions Hotel."

[](https://expedia.ca/Guatemala-City-Hotels-Clarion-Suites-Guatemala-City.h27811.Hotel-Information)

![Barceló Guatemala City](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/78fae458_y.jpg)

### Barceló Guatemala City

10/10 Excellent

"Clean rooms. Very friendly and helpful staff. Super comfy beds as well! "

[](https://expedia.ca/Guatemala-City-Hotels-Barcelo-Guatemala-City.h2495.Hotel-Information)

![Hotel Soleil La Antigua](https://images.trvl-media.com/lodging/2000000/1520000/1517400/1517336/93bfa68c_y.jpg)

### Hotel Soleil La Antigua

10/10 Excellent

"Amazing place "

[](https://expedia.ca/Antigua-Guatemala-Hotels-Hotel-Soleil-La-Antigua.h1517336.Hotel-Information)

## Frequently asked questions

### What's it like in Santa Ana?

### What's a favorite hotel to stay in Santa Ana?

### How many hotels will I be able to find in Santa Ana?

### If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

### What are the top things to see and do in Santa Ana?