Title: 10 Best Hotels in Santa Ana, Antigua Guatemala for 2026 | Expedia.ca

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# Hotels in Santa Ana, Antigua Guatemala 

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## Check prices for these dates

Tonight

[Dec 22 - Dec 23](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2025-12-22&endDate=2025-12-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Dec 23 - Dec 24](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2025-12-23&endDate=2025-12-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Santa Ana hotels

![Front of property](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/07c82154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Villa, 4 Bedrooms | Terrace/patio](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/e93ede8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food court](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/ccc0a892.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Villa, Accessible, Mountain View | Private kitchen](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/59cb6c23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villas Santa Ana-Ricardo

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Villas-Santa-Ana-Ricardo.h36156032.Hotel-Information)

Santa Ana

8.6/10

Excellent

(12)

"Space was clean and had a cozy vibe."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Evelin

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Villas-Santa-Ana-Ricardo.h36156032.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/2c2e8198.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/263c7d09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/2499f453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/1914e3c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Buho B&B

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Casa-Buho-BB.h91818768.Hotel-Information)

Santa Ana

9.2/10

Wonderful

(48)

"Great place !!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Abner Israel Polanco

CA $72

CA $87 total

includes taxes & fees

Jan 19 - Jan 20, 2026

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Casa-Buho-BB.h91818768.Hotel-Information)

![Garden view](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/4afb3fa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/e33ebe2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Room, Garden View](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/d65461db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Twin Room, Balcony, City View](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/f4dd18dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hostal Casa Buho

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hostal-Casa-Buho.h91818295.Hotel-Information)

Santa Ana

8.6/10

Excellent

(21)

"Nice clean affordable accomodations and very accomodating and amicable hosts."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Feng

CA $64

CA $79 total

includes taxes & fees

Dec 23 - Dec 24

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hostal-Casa-Buho.h91818295.Hotel-Information)

![Reception hall](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/78fae458.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor banquet area](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/321f0a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/2254de16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor wedding](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/3ec8ef4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Barceló Guatemala City

[](https://www.expedia.ca/Guatemala-City-Hotels-Barcelo-Guatemala-City.h2495.Hotel-Information)

22.7 km from Santa Ana

9.2/10

Wonderful

(3120)

"Friendly staff , wonderful beds. Breakfast was great and large variety of foods. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Parker

CA $114

CA $139 total

includes taxes & fees

Jan 3 - Jan 4, 2026

[](https://www.expedia.ca/Guatemala-City-Hotels-Barcelo-Guatemala-City.h2495.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/22000000/21430000/21424900/21424807/8f9e15af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/22000000/21430000/21424900/21424807/bf0b3b10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Double Room, Mountain View | Terrace/patio](https://images.trvl-media.com/lodging/22000000/21430000/21424900/21424807/39debfca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/22000000/21430000/21424900/21424807/c10bfe9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Panchoy

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-HOTEL-PANCHOY.h21424807.Hotel-Information)

Historic Center, 1.1 km from Santa Ana

8.4/10

Very good

(275)

"Nice staff and good location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Luis

CA $66

CA $80 total

includes taxes & fees

Dec 23 - Dec 24

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-HOTEL-PANCHOY.h21424807.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/75000000/74650000/74641700/74641639/217fd81a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/75000000/74650000/74641700/74641639/804f2030.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/75000000/74650000/74641700/74641639/29a47aac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/75000000/74650000/74641700/74641639/5bb7bed4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Good Hotel Guatemala City

[](https://www.expedia.ca/Guatemala-City-Hotels-Good-Hotel-Guatemala-City.h74641639.Hotel-Information)

23.9 km from Santa Ana

9.4/10

Exceptional

(248)

"Great place to stay in the city"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cesar

CA $133

CA $162 total

includes taxes & fees

Dec 23 - Dec 24

[](https://www.expedia.ca/Guatemala-City-Hotels-Good-Hotel-Guatemala-City.h74641639.Hotel-Information)

![Hallway](https://images.trvl-media.com/lodging/80000000/79570000/79566100/79566041/7272e809.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room](https://images.trvl-media.com/lodging/80000000/79570000/79566100/79566041/9343e4d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/80000000/79570000/79566100/79566041/996b87f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/80000000/79570000/79566100/79566041/19872600.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hostal Donde Regina

[](https://www.expedia.ca/Guatemala-City-Hotels-Hostal-Donde-Regina.h79566041.Hotel-Information)

21 km from Santa Ana

9.2/10

Wonderful

(169)

"Spotless room and good staff service"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christian

CA $66

CA $81 total

includes taxes & fees

Dec 23 - Dec 24

[](https://www.expedia.ca/Guatemala-City-Hotels-Hostal-Donde-Regina.h79566041.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/058db2db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/abfb8ea4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/101420c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/d66e2431.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Posada de Don Rodrigo Antigua

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Posada-De-Don-Rodrigo-Antigua.h3948905.Hotel-Information)

Historic Center, 1.5 km from Santa Ana

9.4/10

Exceptional

(651)

"Friendly staff, clean rooms the location was excellent. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elias

CA $218

CA $300 total

includes taxes & fees

Jan 21 - Jan 22, 2026

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Posada-De-Don-Rodrigo-Antigua.h3948905.Hotel-Information)

![In-room safe, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/9000000/8340000/8336300/8336251/98bd4948.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/9000000/8340000/8336300/8336251/554976a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8340000/8336300/8336251/9c9c2090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/9000000/8340000/8336300/8336251/ce79fda4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Adriatika Hotel & Residence

[](https://www.expedia.ca/Guatemala-City-Hotels-Adriatika-Hotel-Boutique.h8336251.Hotel-Information)

21.9 km from Santa Ana

9.4/10

Exceptional

(952)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alejandro

CA $125

CA $152 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/Guatemala-City-Hotels-Adriatika-Hotel-Boutique.h8336251.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26600/26567/7c46a4a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 Queen Bed Balcony](https://images.trvl-media.com/lodging/1000000/30000/26600/26567/436e3574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26600/26567/d3629706.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26600/26567/9b676ee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wyndham Garden Guatemala City

[](https://www.expedia.ca/Guatemala-City-Hotels-Wyndham-Garden-Guatemala-City.h26567.Hotel-Information)

23.2 km from Santa Ana

9.2/10

Wonderful

(1622)

"Location and hotel is amazing and the staff is very helpful"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Martha

CA $129

CA $158 total

includes taxes & fees

Jan 1 - Jan 2, 2026

[](https://www.expedia.ca/Guatemala-City-Hotels-Wyndham-Garden-Guatemala-City.h26567.Hotel-Information)

![Interior entrance](https://images.trvl-media.com/lodging/1000000/50000/48600/48502/11a701a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/48600/48502/9f5ab770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/50000/48600/48502/c9c02249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/48600/48502/0cced0a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tikal Futura Hotel & Convention Center

[](https://www.expedia.ca/Guatemala-City-Hotels-Grand-Tikal-Futura-Hotel.h48502.Hotel-Information)

20.2 km from Santa Ana

9.0/10

Wonderful

(1005)

"Great place to stay and relax. Beautiful rooms and great staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tracy

CA $125

CA $152 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/Guatemala-City-Hotels-Grand-Tikal-Futura-Hotel.h48502.Hotel-Information)

![Breakfast, lunch, dinner served; international cuisine, garden views ](https://images.trvl-media.com/lodging/1000000/30000/27900/27811/7e9dc3cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Serves lunch, dinner, and happy hour](https://images.trvl-media.com/lodging/1000000/30000/27900/27811/af2bd370.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27900/27811/214924d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Serves lunch, dinner, and happy hour](https://images.trvl-media.com/lodging/1000000/30000/27900/27811/ceef98f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Clarion Suites Guatemala City

[](https://www.expedia.ca/Guatemala-City-Hotels-Clarion-Suites-Guatemala-City.h27811.Hotel-Information)

23.3 km from Santa Ana

9.0/10

Wonderful

(1007)

"Loved the stay here!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nora

CA $139

CA $170 total

includes taxes & fees

Dec 25 - Dec 26

[](https://www.expedia.ca/Guatemala-City-Hotels-Clarion-Suites-Guatemala-City.h27811.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/17000000/16230000/16223700/16223612/52a25915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/17000000/16230000/16223700/16223612/de4de24c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/17000000/16230000/16223700/16223612/93cd0a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/17000000/16230000/16223700/16223612/6a7c2adc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### In & Out Hotel

[](https://www.expedia.ca/Guatemala-City-Hotels-In-Out-Hotel.h16223612.Hotel-Information)

20.9 km from Santa Ana

8.6/10

Excellent

(808)

"Clean room , helpful staff for getting a taxi, loved full breakfast"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Deborah

[](https://www.expedia.ca/Guatemala-City-Hotels-In-Out-Hotel.h16223612.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/1300/1234/fc36525d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1300/1234/8d5c434b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/1300/1234/a0987f51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1300/1234/ae4e096b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Guatemala City by IHG

[](https://www.expedia.ca/Guatemala-City-Hotels-Holiday-Inn-Guatemala-City.h1234.Hotel-Information)

23.1 km from Santa Ana

9.2/10

Wonderful

(1004)

"Best Holiday Inn I've ever stayed in! Really nice. Good restaurant, nice staff. Be patient with the hot water. It'll arrive in a minute or two, and be good thereafter."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alan

CA $127

CA $155 total

includes taxes & fees

Dec 25 - Dec 26

[](https://www.expedia.ca/Guatemala-City-Hotels-Holiday-Inn-Guatemala-City.h1234.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/14000000/13410000/13408400/13408335/961e06a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Double Room, 1 Double Bed, Private Bathroom, Courtyard Area](https://images.trvl-media.com/lodging/14000000/13410000/13408400/13408335/a11fc208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/14000000/13410000/13408400/13408335/d41cb438.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fountain](https://images.trvl-media.com/lodging/14000000/13410000/13408400/13408335/876ec4bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Las Camelias Inn

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Las-Camelias-Inn.h13408335.Hotel-Information)

Historic Center, 1.2 km from Santa Ana

8.8/10

Excellent

(580)

"Very good place for my stay in Antigua. They were so helpful in storing my luggages away even after check out for a whole day for free when I went for the volcano hike. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Joel

CA $92

CA $114 total

includes taxes & fees

Dec 23 - Dec 24

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Las-Camelias-Inn.h13408335.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/b1a04679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/ac35c64b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, 1 King Bed](https://images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/5b5886bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/70585ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Centric Guatemala City

[](https://www.expedia.ca/Guatemala-City-Hotels-Hyatt-Centric-Guatemala-City.h19317570.Hotel-Information)

23.3 km from Santa Ana

9.6/10

Exceptional

(786)

"the hotel is perfectly located. The staff is happy, courteous, helpful. Food is good. Great Breakfast Buffett, good room service. We will return every time we go back to Guatemala City."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Fernando

CA $145

CA $177 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/Guatemala-City-Hotels-Hyatt-Centric-Guatemala-City.h19317570.Hotel-Information)

![Indoor pool, outdoor pool, sun loungers](https://images.trvl-media.com/lodging/7000000/6450000/6442800/6442800/f77e3561.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6450000/6442800/6442800/9956d973.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Double Room](https://images.trvl-media.com/lodging/7000000/6450000/6442800/6442800/88a468d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/7000000/6450000/6442800/6442800/e3eb72b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Kawilal Hotel

[](https://www.expedia.ca/Amatitlan-Hotels-Kawilal-Hotel.h6442800.Hotel-Information)

13.7 km from Santa Ana

9.0/10

Wonderful

(132)

"Beautiful pool and spa with thermal water! Only hotel guests are allowed to have use of the installations. The massage was amazing! I would love to go back "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ana

CA $149

CA $182 total

includes taxes & fees

Jan 6 - Jan 7, 2026

[](https://www.expedia.ca/Amatitlan-Hotels-Kawilal-Hotel.h6442800.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/1000000/900000/898800/898717/4d4a4357.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/1000000/900000/898800/898717/1b86e0c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, Multiple Beds, Smoking](https://images.trvl-media.com/lodging/1000000/900000/898800/898717/a9fcf582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/900000/898800/898717/641dbe3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Hotel Stofella

[](https://www.expedia.ca/Guatemala-City-Hotels-Best-Western-Plus-Hotel-Stofella.h898717.Hotel-Information)

23.3 km from Santa Ana

8.8/10

Excellent

(1001)

"Nice room. Good location. Great staff!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

JOSE MARIANO

CA $129

CA $158 total

includes taxes & fees

Dec 26 - Dec 27

[](https://www.expedia.ca/Guatemala-City-Hotels-Best-Western-Plus-Hotel-Stofella.h898717.Hotel-Information)

![Garden](https://images.trvl-media.com/lodging/1000000/200000/199700/199610/52dae80b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/200000/199700/199610/061f980d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/1000000/200000/199700/199610/50216c27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/200000/199700/199610/2e2e9d46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Guatemala City

[](https://www.expedia.ca/Guatemala-City-Hotels-Hilton-Guatemala-City.h199610.Hotel-Information)

25.9 km from Santa Ana

8.6/10

Excellent

(680)

"Great stay and amazing property "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hugo

CA $142

CA $173 total

includes taxes & fees

Jan 11 - Jan 12, 2026

[](https://www.expedia.ca/Guatemala-City-Hotels-Hilton-Guatemala-City.h199610.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/11000000/10250000/10247600/10247555/c2a818d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Suite](https://images.trvl-media.com/lodging/11000000/10250000/10247600/10247555/f688f052.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/11000000/10250000/10247600/10247555/898e4a3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/11000000/10250000/10247600/10247555/5ee1a697.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ciel-Luxe Hotels

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Los-Olivos-Hotel-Boutique-Y-Restaurante.h10247555.Hotel-Information)

Historic Center, 1.4 km from Santa Ana

8.6/10

Excellent

(349)

"Excellent customer service from the staff, great food, room was very clean and a block away from the park."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rodrigo

CA $148

CA $180 total

includes taxes & fees

Dec 23 - Dec 24

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Los-Olivos-Hotel-Boutique-Y-Restaurante.h10247555.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-05&endDate=2026-01-06&regionId=553248635975847775&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. 

- Historic Center
- Barrio de La Concepción

![](https://mediaim.expedia.com/destination/1/74ddc5a8bc392ba990ada31c1bf76007.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/bd4f4cf2ac6696e4d9dd7a1c5261170e.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/b494c5622ebb15c1dd7e91ce76ce75f2.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/3d9e1f30df3a11ff4ad43007765de7e3.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/b2651b17b5e3f38b232fea61824aba4c.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=911355684795535360)

![Historic Center map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:o%7EzwAthyhPXoK_%40%7Di%40ri%40a%40j%40fv%40yj%40f%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=r_Zy9R--c8e6nlgWjV2_dDRw1Is=)

### Historic Center

While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=911355684795535360)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=911356092010033152)

![Barrio de La Concepción map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mqzwAlqwhPIwL%60E%7DHfFdBW%60SgKL&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Z_eq5PTC3hcK7WdhMP04Ad5umoE=)

### Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=911356092010033152)

## Top Santa Ana Hotel Reviews

![Hotel Camino Real Antigua](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/17346378_y.jpg)

### Hotel Camino Real Antigua

10/10 Excellent

"Yes perfectly "

[](https://expedia.ca/Antigua-Guatemala-Hotels-Hotel-Camino-Real-Antigua.h3084914.Hotel-Information)

![Tikal Futura Hotel & Convention Center](https://images.trvl-media.com/lodging/1000000/50000/48600/48502/11a701a2_y.jpg)

### Tikal Futura Hotel & Convention Center

10/10 Excellent

"Excellent as always."

[](https://expedia.ca/Guatemala-City-Hotels-Grand-Tikal-Futura-Hotel.h48502.Hotel-Information)

![Adriatika Hotel & Residence](https://images.trvl-media.com/lodging/9000000/8340000/8336300/8336251/98bd4948_y.jpg)

### Adriatika Hotel & Residence

10/10 Excellent

"Wonderful spacious room with a view of the city. I particularly liked the bedroom with a locking door."

[](https://expedia.ca/Guatemala-City-Hotels-Adriatika-Hotel-Boutique.h8336251.Hotel-Information)

![Hotel Posada de Don Rodrigo Antigua](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/058db2db_y.jpg)

### Hotel Posada de Don Rodrigo Antigua

10/10 Excellent

"First time in Guatemala in 30 years and first time for my wife. Honestly what an amazing experience I couldn't have asked for a better place to stay....the room ... Amazing, the food ... Amazing... The staff ... Amazing. I give this place 1 million stars"

[](https://expedia.ca/Antigua-Guatemala-Hotels-Hotel-Posada-De-Don-Rodrigo-Antigua.h3948905.Hotel-Information)

![Barceló Guatemala City](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/78fae458_y.jpg)

### Barceló Guatemala City

10/10 Excellent

"The staff was very helpful and friendly. Excellent buffet breakfast."

[](https://expedia.ca/Guatemala-City-Hotels-Barcelo-Guatemala-City.h2495.Hotel-Information)

![Hotel Casa Veranda](https://images.trvl-media.com/lodging/2000000/1520000/1510700/1510614/aa4e2bf5_y.jpg)

### Hotel Casa Veranda

10/10 Excellent

"Beautiful views, beautiful rooms with balconies! Very professional staff and extremely friendly! I will be back just to stay here! And the food was amazing! The croquetas and michelada were delicious! Muchas Gracias!!!"

[](https://expedia.ca/Guatemala-City-Hotels-Hotel-Casa-Veranda.h1510614.Hotel-Information)

![Porta Hotel Antigua](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/b3d7f8e6_y.jpg)

### Porta Hotel Antigua

10/10 Excellent

"Great service "

[](https://expedia.ca/Antigua-Guatemala-Hotels-Porta-Hotel-Antigua.h5545.Hotel-Information)

![Hotel Soleil La Antigua](https://images.trvl-media.com/lodging/2000000/1520000/1517400/1517336/93bfa68c_y.jpg)

### Hotel Soleil La Antigua

10/10 Excellent

"They gave me a room upgrade due to my VIP status and also offered the discount in food and beverages."

[](https://expedia.ca/Antigua-Guatemala-Hotels-Hotel-Soleil-La-Antigua.h1517336.Hotel-Information)

![Wyndham Garden Guatemala City](https://images.trvl-media.com/lodging/1000000/30000/26600/26567/449c3cd0_y.jpg)

### Wyndham Garden Guatemala City

10/10 Excellent

"The room was spacious and very clean. Breakfast was great!"

[](https://expedia.ca/Guatemala-City-Hotels-Wyndham-Garden-Guatemala-City.h26567.Hotel-Information)

## Frequently asked questions

### What's it like in Santa Ana?

### What's a favorite hotel to stay in Santa Ana?

### How many hotels will I be able to find in Santa Ana?

### If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

### What are the top things to see and do in Santa Ana?