Title: 10 Best Hotels in Santa Ana, Antigua Guatemala for 2025 | Expedia.ca

  

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![Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.](https://images.trvl-media.com/place/553248635975847775/dbfc8e66-dcda-4ff9-9ea4-b39c7cec35ab.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Hotels in Santa Ana, Antigua Guatemala

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## Go beyond your typical stay in Santa Ana

Apart hotel

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&lodging=APART_HOTEL)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&travelerType=family_friendly)

Spa

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&amenities=SPA_ON_SITE)

Cabin

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&lodging=CABIN)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&amenities=POOL)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&amenities=HOT_TUB)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&lodging=APARTMENT)

Villa

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&lodging=VILLA)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Antigua+Guatemala%2C+Sacatep%C3%A9quez%2C+Guatemala&regionId=553248635975847775&latLong=14.549114%2C-90.724172&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&amenities=PETS)

## Check prices for these dates

Tonight

[Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2025-10-30&endDate=2025-10-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2025-10-31&endDate=2025-11-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Santa Ana hotels and places to stay

![Interior](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/2c2e8198.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/2499f453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/1914e3c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/fcd0cce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Buho B&B

Santa Ana

9.2/10

Wonderful

(46)

"Great place !!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Abner Israel Polanco

CA $92

CA $112 total

includes taxes & fees

Nov 4 - Nov 5

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Casa-Buho-BB.h91818768.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/07c82154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Villa, 4 Bedrooms | Terrace/patio](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/e93ede8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Villa, Accessible, Mountain View | Private kitchen](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/59cb6c23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food court](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/ccc0a892.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villas Santa Ana-Ricardo

Santa Ana

8.4/10

Very good

(11)

"Very nice place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maynor

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Villas-Santa-Ana-Ricardo.h36156032.Hotel-Information)

![Garden view](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/4afb3fa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/1a5632cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/e33ebe2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Room, Garden View](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/d65461db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hostal Casa Buho

Santa Ana

8.6/10

Excellent

(21)

"Nice clean affordable accomodations and very accomodating and amicable hosts."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Feng

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hostal-Casa-Buho.h91818295.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/108000000/107730000/107726600/107726544/08e02f51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/108000000/107730000/107726600/107726544/f906119c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/108000000/107730000/107726600/107726544/b309f307.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Triple Room, Non Smoking](https://images.trvl-media.com/lodging/108000000/107730000/107726600/107726544/c95cec25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La guarida del caudillo

Santa Ana

CA $35

CA $44 total

includes taxes & fees

Nov 4 - Nov 5

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-La-Guarida-Del-Caudillo.h107726544.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/114000000/113200000/113195100/113195058/a6bfe9cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shared fridge, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/114000000/113200000/113195100/113195058/4d1d1471.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/114000000/113200000/113195100/113195058/0627e301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Quadruple Room, Mountain View](https://images.trvl-media.com/lodging/114000000/113200000/113195100/113195058/2ebd65de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Castillo De Los Gigantes

Santa Ana

CA $33

CA $40 total

includes taxes & fees

Oct 31 - Nov 1

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Castillo-De-Los-Gigantes.h113195058.Hotel-Information)

![3 outdoor pools, pool umbrellas](https://images.trvl-media.com/lodging/2000000/1520000/1517400/1517336/93bfa68c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/2000000/1520000/1517400/1517336/cc442321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1520000/1517400/1517336/5841f779.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/2000000/1520000/1517400/1517336/02246420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Soleil La Antigua

1.8 km from Santa Ana

8.6/10

Excellent

(1002)

"All staff are nice, excellent service, good price, good location. The people of Guatemala are very kind!!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nancy

CA $234

CA $285 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Soleil-La-Antigua.h1517336.Hotel-Information)

![Fitness studio](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/20929971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room (All rooms are different)](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/7b28f528.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/4405e75a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Building design](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/082f03cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Museo Spa Casa Santo Domingo

Barrio de La Concepción, 1.1 km from Santa Ana

9.2/10

Wonderful

(1003)

"Beautiful property, very clean, staff were wonderful!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rachel

CA $363

CA $459 total

includes taxes & fees

Oct 31 - Nov 1

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Museo-Spa-Casa-Santo-Domingo.h1246555.Hotel-Information)

![Indoor wedding](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/c13345a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor banquet area](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/321f0a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/24089eb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/963beb5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Barceló Guatemala City

22.7 km from Santa Ana

9.2/10

Wonderful

(3071)

"Staff was very accommodating, hotel great quality! Excellent go to hotel when visiting Guatemala City!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jacqulyne Danielle

CA $144

CA $177 total

includes taxes & fees

Nov 11 - Nov 12

[](https://www.expedia.ca/Guatemala-City-Hotels-Barcelo-Guatemala-City.h2495.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/014bd4a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Master Suite](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/3cede885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/331b5eea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch plasma TV with cable channels, TV, books](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/a487c1ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Los Pasos Boutique Hotel & Spa

0.7 km from Santa Ana

9.4/10

Exceptional

(1003)

"Gorgeous property with amazing view. The staff’s attention to detail and service was great and breakfast was delish! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nathalie

CA $198

CA $241 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Los-Pasos.h3856168.Hotel-Information)

![Egyptian cotton sheets, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836192/3b9c7ead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836192/9e1d9d20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836192/709e8c1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836192/8a80f44e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### El Convento Boutique Hotel

Historic Center, 1.5 km from Santa Ana

9.4/10

Exceptional

(780)

"Great hotel!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rafael

CA $273

CA $354 total

includes taxes & fees

Oct 31 - Nov 1

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-El-Convento-Boutique-Hotel.h1836192.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/13000000/12850000/12847300/12847243/84429269.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/13000000/12850000/12847300/12847243/2c82f338.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/13000000/12850000/12847300/12847243/fa950ecf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/13000000/12850000/12847300/12847243/3b89d44e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Naif Boutique Hotel

Historic Center, 1.4 km from Santa Ana

8.8/10

Excellent

(357)

"Absolutely recommend to stay here great stay !! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brianna

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Naif-Boutique-Hotel-Gallery.h12847243.Hotel-Information)

![Breakfast, lunch, dinner served; international cuisine, garden views ](https://images.trvl-media.com/lodging/1000000/30000/27900/27811/e487f2b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/27900/27811/d751d638.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27900/27811/9271a899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, Multiple Beds, Non Smoking (Upgrade) | Private kitchen](https://images.trvl-media.com/lodging/1000000/30000/27900/27811/93a5ace2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Clarion Suites Guatemala City

23.3 km from Santa Ana

9.0/10

Wonderful

(1002)

"Excellent hotel !! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sergio

CA $146

CA $179 total

includes taxes & fees

Nov 28 - Nov 29

[](https://www.expedia.ca/Guatemala-City-Hotels-Clarion-Suites-Guatemala-City.h27811.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/b1a04679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/443e134d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/ac35c64b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/70585ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Centric Guatemala City

23.3 km from Santa Ana

9.6/10

Exceptional

(762)

"Amazing experience at this beautiful hotel. All the staff is friendly and welcoming Would highly recommend it "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Keilly

CA $222

CA $271 total

includes taxes & fees

Nov 29 - Nov 30

[](https://www.expedia.ca/Guatemala-City-Hotels-Hyatt-Centric-Guatemala-City.h19317570.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/5000000/4360000/4359800/4359747/ea2518af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, Multiple Beds (Don Pedro)](https://images.trvl-media.com/lodging/5000000/4360000/4359800/4359747/1e314c9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Bedrooms (Dona Luisa) | Terrace/patio](https://images.trvl-media.com/lodging/5000000/4360000/4359800/4359747/fdb7b01b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/5000000/4360000/4359800/4359747/18cfc72e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### All Suite El Marques de Antigua

1 km from Santa Ana

9.2/10

Wonderful

(285)

"Excellent place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

jorge

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-All-Suite-El-Marques-De-Antigua.h4359747.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/104000000/103130000/103126800/103126773/0239c2b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/104000000/103130000/103126800/103126773/8beeaba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Studio Suite 203 | Bathroom](https://images.trvl-media.com/lodging/104000000/103130000/103126800/103126773/c0ec7452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Studio Suite 203 | Garden view](https://images.trvl-media.com/lodging/104000000/103130000/103126800/103126773/8bc083db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mestizo Cortijo

4.3 km from Santa Ana

9.0/10

Wonderful

(85)

"Nice place to stay and enjoy Antigua Guatemala "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Allan

CA $172

CA $210 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Ciudad-Vieja-Hotels-Mestizo-Cortijo.h103126773.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/058db2db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/101420c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/d66e2431.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/b69a6270.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Posada de Don Rodrigo Antigua

Historic Center, 1.5 km from Santa Ana

9.4/10

Exceptional

(629)

"Great hotel right in the center of the action. The facilities and hotel vibes are awesome! The restaurant has great food and all the staff is kind all around. The beds I found to be uncomfortable, but not a deal breaker as the hotel pros outweigh the cons. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Juan

CA $220

CA $304 total

includes taxes & fees

Nov 11 - Nov 12

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Posada-De-Don-Rodrigo-Antigua.h3948905.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/4000000/3430000/3430000/3429972/c2af4620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3430000/3430000/3429972/7e3a6fa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/4000000/3430000/3430000/3429972/a08b69c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite](https://images.trvl-media.com/lodging/4000000/3430000/3430000/3429972/b965c955.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Las Marías

1.9 km from Santa Ana

9.2/10

Wonderful

(424)

"Safe, clean & good service "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lesbia

CA $124

CA $151 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Las-Marias.h3429972.Hotel-Information)

![4 restaurants, breakfast, lunch, dinner served; international cuisine](https://images.trvl-media.com/lodging/1000000/560000/558200/558105/16df8b19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, pillowtop beds, minibar](https://images.trvl-media.com/lodging/1000000/560000/558200/558105/a855c123.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 outdoor pools, sun loungers](https://images.trvl-media.com/lodging/1000000/560000/558200/558105/107a1949.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 outdoor pools, sun loungers](https://images.trvl-media.com/lodging/1000000/560000/558200/558105/d07c12ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### InterContinental Real Guatemala by IHG

23.2 km from Santa Ana

9.2/10

Wonderful

(1010)

"Overall great hotel with excellent service."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Pierre

CA $236

CA $305 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Guatemala-City-Hotels-Real-InterContinental-Guatemala.h558105.Hotel-Information)

![2 treatment rooms](https://images.trvl-media.com/lodging/18000000/17410000/17403700/17403610/111c1f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17410000/17403700/17403610/fd2021bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![City view](https://images.trvl-media.com/lodging/18000000/17410000/17403700/17403610/4114c275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/18000000/17410000/17403700/17403610/0b227f2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Las Americas

22.3 km from Santa Ana

8.4/10

Very good

(1001)

"Great service nice rooms"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

WILBER

CA $121

CA $147 total

includes taxes & fees

Oct 31 - Nov 1

[](https://www.expedia.ca/Guatemala-City-Hotels-Hotel-Las-Americas.h17403610.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/b3d7f8e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/5f2c5f66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/cc2d383a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/da5ce8e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Porta Hotel Antigua

1.1 km from Santa Ana

9.4/10

Exceptional

(1008)

"Outstanding hotel and location, my family and I had a blast, super friendly staff, extremely clean rooms and amenities, easy transportation from hotel to parking or viceversa, the food is exceptional a bit pricey but worth every penny! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Frank

CA $217

CA $292 total

includes taxes & fees

Nov 11 - Nov 12

[](https://www.expedia.ca/Antigua-Guatemala-Hotels-Porta-Hotel-Antigua.h5545.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-13&endDate=2025-11-14&regionId=553248635975847775&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

-   Historic Center
-   Barrio de La Concepción

![](https://mediaim.expedia.com/destination/1/74ddc5a8bc392ba990ada31c1bf76007.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/bd4f4cf2ac6696e4d9dd7a1c5261170e.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/b494c5622ebb15c1dd7e91ce76ce75f2.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/3d9e1f30df3a11ff4ad43007765de7e3.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/b2651b17b5e3f38b232fea61824aba4c.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=911355684795535360)

![Historic Center map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:o%7EzwAthyhPXoK_%40%7Di%40ri%40a%40j%40fv%40yj%40f%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=r_Zy9R--c8e6nlgWjV2_dDRw1Is=)

### Historic Center

While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=911355684795535360)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=911356092010033152)

![Barrio de La Concepción map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mqzwAlqwhPIwL%60E%7DHfFdBW%60SgKL&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Z_eq5PTC3hcK7WdhMP04Ad5umoE=)

### Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=911356092010033152)

## Top Santa Ana Hotel Reviews

![InterContinental Real Guatemala by IHG](//images.trvl-media.com/lodging/1000000/560000/558200/558105/16df8b19_y.jpg)

### InterContinental Real Guatemala by IHG

10/10 Excellent

" Our entire experience from check-in to check out what’s phenomenal. Lezlie, member of management was extremely helpful. Guido, from the club lounge was magnificent. The pool area was very enjoyable and the jacuzzi, perfectly comfortable. We will definitely stay here again!!"

[](https://expedia.ca/Guatemala-City-Hotels-Real-InterContinental-Guatemala.h558105.Hotel-Information)

![Hotel Museo Spa Casa Santo Domingo](//images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/20929971_y.jpg)

### Hotel Museo Spa Casa Santo Domingo

10/10 Excellent

"Room was perfect and always organize Staff very friendly and very polite. "

[](https://expedia.ca/Antigua-Guatemala-Hotels-Hotel-Museo-Spa-Casa-Santo-Domingo.h1246555.Hotel-Information)

![El Carmen Hotel](//images.trvl-media.com/lodging/2000000/1220000/1211500/1211421/97e9d009_y.jpg)

### El Carmen Hotel

10/10 Excellent

"Beautiful hotel, very nice rooftop terrace and centrally located. "

[](https://expedia.ca/Antigua-Guatemala-Hotels-El-Carmen-Hotel.h1211421.Hotel-Information)

![Barceló Guatemala City](//images.trvl-media.com/lodging/1000000/10000/2500/2495/321f0a1f_y.jpg)

### Barceló Guatemala City

10/10 Excellent

"Excellent customer service"

[](https://expedia.ca/Guatemala-City-Hotels-Barcelo-Guatemala-City.h2495.Hotel-Information)

![Hotel Camino Real Antigua](//images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/17346378_y.jpg)

### Hotel Camino Real Antigua

10/10 Excellent

"Y"

[](https://expedia.ca/Antigua-Guatemala-Hotels-Hotel-Camino-Real-Antigua.h3084914.Hotel-Information)

![Porta Hotel Antigua](//images.trvl-media.com/lodging/1000000/10000/5600/5545/b3d7f8e6_y.jpg)

### Porta Hotel Antigua

10/10 Excellent

"Outstanding hotel and location, my family and I had a blast, super friendly staff, extremely clean rooms and amenities, easy transportation from hotel to parking or viceversa, the food is exceptional a bit pricey but worth every penny! "

[](https://expedia.ca/Antigua-Guatemala-Hotels-Porta-Hotel-Antigua.h5545.Hotel-Information)

![Hyatt Centric Guatemala City](//images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/b1a04679_y.jpg)

### Hyatt Centric Guatemala City

10/10 Excellent

"Amazing experience at this beautiful hotel. All the staff is friendly and welcoming Would highly recommend it "

[](https://expedia.ca/Guatemala-City-Hotels-Hyatt-Centric-Guatemala-City.h19317570.Hotel-Information)

![Hotel Las Americas](//images.trvl-media.com/lodging/18000000/17410000/17403700/17403610/111c1f7f_y.jpg)

### Hotel Las Americas

10/10 Excellent

"The rooms are very clean and comfortable in every way. The fixtures in the bathroom are a bit dated, but everything is clean and in perfect working order. The staff is unbelievably polite and helpful. There is a restaurant in the hotel and the food is absolutely wonderful with great, attentive service. I would recommend this hotel without any hesitation."

[](https://expedia.ca/Guatemala-City-Hotels-Hotel-Las-Americas.h17403610.Hotel-Information)

![Adriatika Hotel & Residence](//images.trvl-media.com/lodging/9000000/8340000/8336300/8336251/98bd4948_y.jpg)

### Adriatika Hotel & Residence

10/10 Excellent

"Very clean and comfortable "

[](https://expedia.ca/Guatemala-City-Hotels-Adriatika-Hotel-Boutique.h8336251.Hotel-Information)

## Frequently asked questions

### What's it like in Santa Ana?

> Travelers to the Santa Ana neighborhood in Antigua Guatemala will be sure to enjoy their stay.

### What's a favorite hotel to stay in Santa Ana?

> Based on Expedia customer reviews, [Casa Buho B&B](https://www.expedia.ca/Antigua-Guatemala-Hotels-Casa-Buho-BB.h91818768.Hotel-Information) is the highest ranked property in Santa Ana. This hotel offers a restaurant and free parking.

### How many hotels will I be able to find in Santa Ana?

> If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 18 hotels and other accommodations in Santa Ana.

### If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

> Yes! You'll find that most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in Santa Ana.

### What are the top things to see and do in Santa Ana?

> House of the Giants, Santa Clara Convent, and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, be sure to visit other sights like Tanque La Unión or Museo del Hermano Pedro.