Title: 10 Best Hotels in Santa Ana, Antigua Guatemala for 2026 | Expedia.ca [Vacation Rentals in Antigua Guatemala](https://expedia.ca/Antigua-Guatemala-Vacation-Rentals.d180589.Travel-Guide-VacationRentals)[Flights to Antigua Guatemala](https://expedia.ca/Cheap-Flights-To-Antigua-Guatemala.d180589.Travel-Guide-Flights)[Things to do in Antigua Guatemala](https://expedia.ca/Things-To-Do-In-Antigua-Guatemala.d180589.Travel-Guide-Activities)[Santa Ana Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Ana.d553248635975847775.Car-Rental-Guide)[Santa Ana Vacations](https://expedia.ca/Santa-Ana.d553248635975847775.Destination-Travel-Guides) ![Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.](https://images.trvl-media.com/place/553248635975847775/dbfc8e66-dcda-4ff9-9ea4-b39c7cec35ab.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248635975847775/dbfc8e66-dcda-4ff9-9ea4-b39c7cec35ab.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 30 - Jan 31](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2026-01-30&endDate=2026-01-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 31 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2026-01-31&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635975847775&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Santa Ana hotels ![Front of property](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/7941cd12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/ba9c9f7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV, DVD player](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/a433c511.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Villa, 4 Bedrooms | Terrace/patio](https://images.trvl-media.com/lodging/37000000/36160000/36156100/36156032/39c1518b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villas Santa Ana-Ricardo [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Villas-Santa-Ana-Ricardo.h36156032.Hotel-Information) Santa Ana 8.6/10 Excellent (12 reviews) "Space was clean and had a cozy vibe." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Evelin [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Villas-Santa-Ana-Ricardo.h36156032.Hotel-Information) ![Garden view](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/4afb3fa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, Balcony, Mountain View](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/72ed609c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Twin Room, Balcony, City View](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/f4dd18dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/92000000/91820000/91818300/91818295/1a5632cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hostal Casa Buho [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hostal-Casa-Buho.h91818295.Hotel-Information) Santa Ana 8.6/10 Excellent (22 reviews) "A little too far from everything but as long as you have a car is ok plenty of parking there" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gustavo CA $58 CA $73 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hostal-Casa-Buho.h91818295.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/5ec870c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony view](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/6642638c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/2c2e8198.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91820000/91818800/91818768/1914e3c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Buho B&B [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Casa-Buho-BB.h91818768.Hotel-Information) Santa Ana 9.2/10 Wonderful (49 reviews) "Great place !!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Abner Israel Polanco CA $73 CA $88 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Casa-Buho-BB.h91818768.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/123000000/122970000/122962400/122962301/4109fa55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/123000000/122970000/122962400/122962301/b0fcbdb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/123000000/122970000/122962400/122962301/8827643d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, Garden View](https://images.trvl-media.com/lodging/123000000/122970000/122962400/122962301/a6beb5ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel y Restaurante Vista Verde [](https://www.expedia.ca/Santa-Lucia-Milpas-Altas-Hotels-Hotel-Y-Restaurante-Vista-Verde.h122962301.Hotel-Information) 5.9 km from Santa Ana 10/10 Exceptional (3 reviews) "Great room (#3) with high quality mattress, nice towels and pretty bathroom, lacks some toiletries, quiete place with awesome graden views, property rune by their owners, highly recommended! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sergio CA $87 CA $107 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/Santa-Lucia-Milpas-Altas-Hotels-Hotel-Y-Restaurante-Vista-Verde.h122962301.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/37000000/36140000/36132000/36131953/dae8fe94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard, Two Double Beds & Two Single Beds | View from room](https://images.trvl-media.com/lodging/37000000/36140000/36132000/36131953/9eea135c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/37000000/36140000/36132000/36131953/795e325d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard One Double Bed](https://images.trvl-media.com/lodging/37000000/36140000/36132000/36131953/38106f2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel La Posadita Antigua [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-La-Posadita-Antigua.h36131953.Hotel-Information) 1.9 km from Santa Ana 8.8/10 Excellent (45 reviews) "Nice place to stay and good location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alfredo CA $106 CA $131 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-La-Posadita-Antigua.h36131953.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/14000000/13360000/13351600/13351570/24ba8dd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13360000/13351600/13351570/c31b12e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/14000000/13360000/13351600/13351570/4d3ee765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Regional cuisine ](https://images.trvl-media.com/lodging/14000000/13360000/13351600/13351570/ba524ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Genessis [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Genessis.h13351570.Hotel-Information) 0.9 km from Santa Ana 9.2/10 Wonderful (108 reviews) "Gorgeous gorgeous hotel! Staff was so friendly! Will definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandy CA $132 CA $161 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Genessis.h13351570.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/79000000/78510000/78506300/78506276/8ad11e46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/79000000/78510000/78506300/78506276/55e37fec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/79000000/78510000/78506300/78506276/89a5505a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/79000000/78510000/78506300/78506276/de4596c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Don Valentino [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Posada-Don-Valentino.h78506276.Hotel-Information) Historic Center, 1.6 km from Santa Ana 7.4/10 Good (77 reviews) "Great service! Clean rooms and the young guy in front desk was very attentive and helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Azucena CA $67 CA $82 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Posada-Don-Valentino.h78506276.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/4000000/3340000/3333400/3333323/5b698a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/4000000/3340000/3333400/3333323/4fe76cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Fireplace, Mountain View | Living area](https://images.trvl-media.com/lodging/4000000/3340000/3333400/3333323/40ede138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/4000000/3340000/3333400/3333323/1bf4b2fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Posada del Angel [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Posada-Del-Angel.h3333323.Hotel-Information) 1 km from Santa Ana 9.6/10 Exceptional (284 reviews) "We had a great stay! The hotel is a very charming boutique hotel nestled in Antigua. The room was very comfortable and we were able to rest very well. The staff was always very helpful and friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janelle [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Posada-Del-Angel.h3333323.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/111000000/110610000/110606700/110606649/089d7d88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/111000000/110610000/110606700/110606649/16a2418d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/111000000/110610000/110606700/110606649/93c92771.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![43-inch Smart TV with digital channels, Netflix, streaming services](https://images.trvl-media.com/lodging/111000000/110610000/110606700/110606649/a6841d80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luna Maya Boutique Hotel [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Luna-Maya-Boutique-Hotel.h110606649.Hotel-Information) 1.5 km from Santa Ana 9.6/10 Exceptional (27 reviews) "Nice staff , nice breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lesly CA $89 CA $109 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Luna-Maya-Boutique-Hotel.h110606649.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/91000000/90210000/90201300/90201250/1a6773be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/91000000/90210000/90201300/90201250/3710a2e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/91000000/90210000/90201300/90201250/8ddcce70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Studio Suite, 1 Bedroom, City View](https://images.trvl-media.com/lodging/91000000/90210000/90201300/90201250/698394e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Narama zona 13 [](https://www.expedia.ca/Guatemala-City-Hotels-Narama-Zona-13.h90201250.Hotel-Information) 21.3 km from Santa Ana 8.8/10 Excellent (21 reviews) "I chose this place because it was close to the airport, very comfortable bed and very clean very modern and and highly decorated" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) yussef [](https://www.expedia.ca/Guatemala-City-Hotels-Narama-Zona-13.h90201250.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/69000000/68060000/68050700/68050617/bb83e52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast (USD 10 per person)](https://images.trvl-media.com/lodging/69000000/68060000/68050700/68050617/9e6e7dda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/69000000/68060000/68050700/68050617/06a9c6f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/69000000/68060000/68050700/68050617/2838d7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Cacique Real [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Cacique-Real.h68050617.Hotel-Information) 1.8 km from Santa Ana 8.8/10 Excellent (166 reviews) "Very clean rooms and nice outdoor area plus secure parking lot" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ephraim CA $146 CA $178 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Cacique-Real.h68050617.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/14000000/13410000/13408500/13408411/121a939c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/14000000/13410000/13408500/13408411/bcb8a603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/14000000/13410000/13408500/13408411/7b269b1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/14000000/13410000/13408500/13408411/9a9292c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Posada San Vicente [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Posada-San-Vicente.h13408411.Hotel-Information) Historic Center, 1.4 km from Santa Ana 8.0/10 Very good (212 reviews) "Staff is great plus the location " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) RICHARD CA $71 CA $87 total includes taxes & fees Feb 26 - Feb 27 [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Posada-San-Vicente.h13408411.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/33000000/32360000/32352900/32352879/a867c8a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/33000000/32360000/32352900/32352879/4c61396f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Double Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/33000000/32360000/32352900/32352879/fdb0bba7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 2 Queen Beds, Non Smoking | Terrace/patio](https://images.trvl-media.com/lodging/33000000/32360000/32352900/32352879/a0e216d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Meson de Maria [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Meson-De-Maria.h32352879.Hotel-Information) Historic Center, 1.6 km from Santa Ana 9.0/10 Wonderful (194 reviews) "Clean room, friendly staff, great hotel overall. However the wifi wasn't great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Meson-De-Maria.h32352879.Hotel-Information) ![Banquet hall](https://images.trvl-media.com/lodging/8000000/7370000/7363500/7363445/3066689a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/8000000/7370000/7363500/7363445/25397b1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7370000/7363500/7363445/3b74e874.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/8000000/7370000/7363500/7363445/9cf24669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pensativo House Hotel [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Pensativo-House-Hotel.h7363445.Hotel-Information) 1 km from Santa Ana 9.4/10 Exceptional (394 reviews) "Rooms were clean and bed and pillows were comfortable with good A/C. Staff was very helpful and were always ready to assist. Food was excellent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos Alvarez CA $258 CA $328 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Pensativo-House-Hotel.h7363445.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/113000000/112370000/112361800/112361776/7ad5e666.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/113000000/112370000/112361800/112361776/84a05c78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/113000000/112370000/112361800/112361776/5170aa0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/113000000/112370000/112361800/112361776/894b9d7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Indian Palace [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Indian-Palace.h112361776.Hotel-Information) 2.8 km from Santa Ana 9.0/10 Wonderful (31 reviews) "Beautiful view to the volcanics clean area Beautiful pool, good game room i will recommend." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Estuardo CA $99 CA $122 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Indian-Palace.h112361776.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/118000000/117840000/117834100/117834041/ec7c37d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/118000000/117840000/117834100/117834041/1d7a9797.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, free WiFi](https://images.trvl-media.com/lodging/118000000/117840000/117834100/117834041/94f08eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, free WiFi](https://images.trvl-media.com/lodging/118000000/117840000/117834100/117834041/52cdd04e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EL TEJAR HOSTAL [](https://www.expedia.ca/Guatemala-City-Hotels-EL-TEJAR-HOSTAL.h117834041.Hotel-Information) 21 km from Santa Ana 8.0/10 Very good (17 reviews) "Staff very friendly and helpful. Room clean and quiet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ILEANA CA $57 CA $70 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Guatemala-City-Hotels-EL-TEJAR-HOSTAL.h117834041.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/4000000/3430000/3430000/3429972/c2af4620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/4000000/3430000/3430000/3429972/a08b69c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden view](https://images.trvl-media.com/lodging/4000000/3430000/3430000/3429972/4a19cd9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/4000000/3430000/3430000/3429972/60bdfba6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Las Marías [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Las-Marias.h3429972.Hotel-Information) 1.9 km from Santa Ana 9.2/10 Wonderful (435 reviews) "clean room in a good area" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) roghayeh CA $114 CA $139 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Las-Marias.h3429972.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/11000000/10250000/10247600/10247555/c2a818d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/11000000/10250000/10247600/10247555/f27ced07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/11000000/10250000/10247600/10247555/5ee1a697.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite](https://images.trvl-media.com/lodging/11000000/10250000/10247600/10247555/9268b1b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ciel-Luxe Hotels [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Los-Olivos-Hotel-Boutique-Y-Restaurante.h10247555.Hotel-Information) Historic Center, 1.4 km from Santa Ana 8.6/10 Excellent (370 reviews) "Friendly and accomadating staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kaushal [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Los-Olivos-Hotel-Boutique-Y-Restaurante.h10247555.Hotel-Information) ![Superior Room | Terrace/patio](https://images.trvl-media.com/lodging/75000000/74170000/74161300/74161287/a91bca25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room](https://images.trvl-media.com/lodging/75000000/74170000/74161300/74161287/c3e61472.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/75000000/74170000/74161300/74161287/88032965.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/75000000/74170000/74161300/74161287/167a2963.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Noble Hotel [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Casa-Noble-Hotel.h74161287.Hotel-Information) 0.9 km from Santa Ana 9.6/10 Exceptional (182 reviews) "Very nice place!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Zaul CA $148 CA $181 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Casa-Noble-Hotel.h74161287.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/101000000/100450000/100442500/100442451/5c4ec9f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Room, 1 King Bed](https://images.trvl-media.com/lodging/101000000/100450000/100442500/100442451/5f6b814c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![64-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100450000/100442500/100442451/8ccf1f9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100450000/100442500/100442451/dc7a83af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Casa Bansley [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Casa-Bansley.h100442451.Hotel-Information) 2.3 km from Santa Ana 9.8/10 Exceptional (49 reviews) "Property is beautiful and staff are great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $143 CA $174 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Antigua-Guatemala-Hotels-Hotel-Casa-Bansley.h100442451.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-13&endDate=2026-02-14®ionId=553248635975847775&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Santa Ana Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. - Historic Center - Barrio de La Concepción ![](https://mediaim.expedia.com/destination/1/74ddc5a8bc392ba990ada31c1bf76007.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/bd4f4cf2ac6696e4d9dd7a1c5261170e.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/b494c5622ebb15c1dd7e91ce76ce75f2.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/3d9e1f30df3a11ff4ad43007765de7e3.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/b2651b17b5e3f38b232fea61824aba4c.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=911355684795535360) ![Historic Center map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:o%7EzwAthyhPXoK_%40%7Di%40ri%40a%40j%40fv%40yj%40f%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=r_Zy9R--c8e6nlgWjV2_dDRw1Is=) ### Historic Center While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch. [See properties](https://www.expedia.ca/Hotel-Search?regionId=911355684795535360) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=911356092010033152) ![Barrio de La Concepción map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mqzwAlqwhPIwL%60E%7DHfFdBW%60SgKL&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Z_eq5PTC3hcK7WdhMP04Ad5umoE=) ### Barrio de La Concepción While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum. [See properties](https://www.expedia.ca/Hotel-Search?regionId=911356092010033152) ## Top Santa Ana Hotel Reviews ![Barceló Guatemala City](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/78fae458_y.jpg) ### Barceló Guatemala City 10/10 Excellent "Clean rooms. Very friendly and helpful staff. Super comfy beds as well! " [](https://expedia.ca/Guatemala-City-Hotels-Barcelo-Guatemala-City.h2495.Hotel-Information) ![Hotel Las Americas](https://images.trvl-media.com/lodging/18000000/17410000/17403700/17403610/111c1f7f_y.jpg) ### Hotel Las Americas 10/10 Excellent "Good " [](https://expedia.ca/Guatemala-City-Hotels-Hotel-Las-Americas.h17403610.Hotel-Information) ![Hotel Biltmore Guatemala](https://images.trvl-media.com/lodging/2000000/1400000/1397600/1397563/1b77a837_y.jpg) ### Hotel Biltmore Guatemala 10/10 Excellent "Very nice they allowed an early check in great service and room service served from westin delicious burger and chicken kieve" [](https://expedia.ca/Guatemala-City-Hotels-Hotel-Biltmore-Guatemala.h1397563.Hotel-Information) ![Hotel Posada de Don Rodrigo Antigua](https://images.trvl-media.com/lodging/4000000/3950000/3949000/3948905/058db2db_y.jpg) ### Hotel Posada de Don Rodrigo Antigua 10/10 Excellent "The location was good and the courtyard was amazing " [](https://expedia.ca/Antigua-Guatemala-Hotels-Hotel-Posada-De-Don-Rodrigo-Antigua.h3948905.Hotel-Information) ![Hotel Museo Spa Casa Santo Domingo](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/20929971_y.jpg) ### Hotel Museo Spa Casa Santo Domingo 10/10 Excellent "Amazing property beautiful views and grounds large spacious room w a jacuzzi! Lovely staff and restaurant i wish i had more time in antigua and could check out the spa! Ill be back and stay here again " [](https://expedia.ca/Antigua-Guatemala-Hotels-Hotel-Museo-Spa-Casa-Santo-Domingo.h1246555.Hotel-Information) ![Tikal Futura Hotel & Convention Center](https://images.trvl-media.com/lodging/1000000/50000/48600/48502/11a701a2_y.jpg) ### Tikal Futura Hotel & Convention Center 10/10 Excellent "Beautiful place to stay with amazing views! " [](https://expedia.ca/Guatemala-City-Hotels-Grand-Tikal-Futura-Hotel.h48502.Hotel-Information) ![Adriatika Hotel & Residence](https://images.trvl-media.com/lodging/9000000/8340000/8336300/8336251/98bd4948_y.jpg) ### Adriatika Hotel & Residence 10/10 Excellent "everything is great" [](https://expedia.ca/Guatemala-City-Hotels-Adriatika-Hotel-Boutique.h8336251.Hotel-Information) ![Clarion Suites Guatemala City](https://images.trvl-media.com/lodging/1000000/30000/27900/27811/e487f2b2_y.jpg) ### Clarion Suites Guatemala City 10/10 Excellent "Great room immaculate " [](https://expedia.ca/Guatemala-City-Hotels-Clarion-Suites-Guatemala-City.h27811.Hotel-Information) ![Hotel Soleil La Antigua](https://images.trvl-media.com/lodging/2000000/1520000/1517400/1517336/93bfa68c_y.jpg) ### Hotel Soleil La Antigua 10/10 Excellent "Everything was 100% perfect " [](https://expedia.ca/Antigua-Guatemala-Hotels-Hotel-Soleil-La-Antigua.h1517336.Hotel-Information) ## Frequently asked questions ### What's it like in Santa Ana? ### What's a favorite hotel to stay in Santa Ana? ### How many hotels will I be able to find in Santa Ana? ### If I need to cancel my hotel reservation in Santa Ana, will I receive a refund? ### What are the top things to see and do in Santa Ana?