Title: Book The Best Hotels in San Isidro for 2026 from CA $65 - Fully Refundable Options - Expedia.ca [Vacation Rentals in San Isidro](https://expedia.ca/San-Isidro-Vacation-Rentals.d553248635975849120.Travel-Guide-VacationRentals)[San Isidro Car Rentals](https://expedia.ca/Car-Rentals-In-San-Isidro.d553248635975849120.Car-Rental-Guide)[San Isidro Vacation Packages](https://expedia.ca/San-Isidro.d553248635975849120.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in San Isidro from CA $65 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in San Isidro Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=San+Isidro%2C+Matagalpa+Department%2C+Nicaragua®ionId=553248635975849120&latLong=12.867527%2C-86.217584&adults=2&startDate=2025-12-18&d1=2025-12-18&endDate=2025-12-20&d2=2025-12-20&amenities=PETS) ## Check prices for these dates Tonight [Dec 4 - Dec 5](https://www.expedia.ca/Hotel-Search?regionId=553248635975849120&startDate=2025-12-04&endDate=2025-12-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 5 - Dec 6](https://www.expedia.ca/Hotel-Search?regionId=553248635975849120&startDate=2025-12-05&endDate=2025-12-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=553248635975849120&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635975849120&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 29 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/0c38b01d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Villa, 2 Bedrooms, Kitchen | Terrace/patio](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/08e0d821.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/5725a167.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/83a7f8ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vera Eco-Resort San Ramon 8.0/10 Very good (4) "Had an excellent week at the resort. If you need a quiet, relaxing break this is the place to go. There are several kilometers of hiking trails. You can also do horseback riding and be guided through the coffee making process. The rooms are comfortable and clean. Hot water is dependable. Most units have amazing views. The staff are eager to help you enjoy your stay. Especially Stanley, who is a master at the hospitality profession." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $75 CA $103 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/San-Ramon-Hotels-Vera-Eco-Resort.h111250683.Hotel-Information) ![Suite](https://images.trvl-media.com/lodging/7000000/6980000/6975400/6975392/416e82cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6980000/6975400/6975392/de44bb7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/7000000/6980000/6975400/6975392/70db0995.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6980000/6975400/6975392/9fb92231.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hex Esteli Esteli 8.4/10 Very good (181) "Excellent location, very friendly and helpful staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gustavo CA $82 CA $96 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Esteli-Hotels-Hotel-Hex-Esteli.h6975392.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/23000000/22360000/22354600/22354548/fd5c7d18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/23000000/22360000/22354600/22354548/cded845c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/23000000/22360000/22354600/22354548/bf96ce6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Triple Room, Multiple Beds](https://images.trvl-media.com/lodging/23000000/22360000/22354600/22354548/e425e1d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Neblina Jinotega 8.0/10 Very good (6) "Hotel room was confortable, staff was excellent, breakfast delicious. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Salvador CA $55 CA $65 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Jinotega-Hotels-Hotel-Neblina.h22354548.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/11000000/10610000/10608200/10608128/5610bed5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite](https://images.trvl-media.com/lodging/11000000/10610000/10608200/10608128/c3eb5a28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/11000000/10610000/10608200/10608128/ba953a52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/11000000/10610000/10608200/10608128/3b4e9118.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Los Altos Esteli Esteli 8.4/10 Very good (96) "The air conditioner was too noisy, I was only able to sleep thanks to my headphones with noise cancellation. The rest of the hotel it’s ok" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Huberth CA $93 CA $107 total includes taxes & fees Dec 5 - Dec 6 [](https://www.expedia.ca/Esteli-Hotels-Hotel-Los-Altos-Esteli.h10608128.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/102000000/101370000/101363400/101363355/06008370.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/102000000/101370000/101363400/101363355/b5ef6670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/102000000/101370000/101363400/101363355/11da1231.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Single Room](https://images.trvl-media.com/lodging/102000000/101370000/101363400/101363355/f6057274.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Finca Fuente De Vida Esteli 6.0/10 (1) CA $64 CA $74 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Esteli-Hotels-Finca-Fuente-De-Vida.h101363355.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/37000000/36750000/36746300/36746289/61c163b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/37000000/36750000/36746300/36746289/d6e336d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/37000000/36750000/36746300/36746289/f5a120c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/37000000/36750000/36746300/36746289/b326644d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Montebrisa Boutique B&B Matagalpa 9.0/10 Wonderful (38) "Clean rooms, friendly and attentive staff, safe and gated property, delicious breakfast and coffee. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Christopher CA $126 CA $144 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Matagalpa-Hotels-Montebrisa-Boutique-BB.h36746289.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/36000000/35390000/35383700/35383677/490a2257.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/36000000/35390000/35383700/35383677/b4e2ddb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Quadruple Room](https://images.trvl-media.com/lodging/36000000/35390000/35383700/35383677/2256be6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/36000000/35390000/35383700/35383677/0beb29e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Brisas Hotel Matagalpa 10/10 Exceptional (12) "Great hotel will return for a visit when back in matagalpa" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dylan CA $70 CA $81 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Matagalpa-Hotels-Brisas-Hotel.h35383677.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/96000000/95050000/95049000/95048999/w1640h1230x0y565-b8ca013c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95050000/95049000/95048999/w1640h1230x0y565-24b2a70c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Studio Suite, 2 Bedrooms | Living area](https://images.trvl-media.com/lodging/96000000/95050000/95049000/95048999/6d8816ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cabin](https://images.trvl-media.com/lodging/96000000/95050000/95049000/95048999/25b1edf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### H & R Ranch Resort Esteli 8.0/10 Very good (25) "Clean rooms, excellent staff, beautiful views! Tranquilo, Tranquilo!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jon CA $116 CA $134 total includes taxes & fees Dec 10 - Dec 11 [](https://www.expedia.ca/Esteli-Hotels-H-R-Ranch-Resort.h95048999.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-18&endDate=2025-12-19®ionId=553248635975849120&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSan-Isidro-Hotels.d553248635975849120.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSan-Isidro-Hotels.d553248635975849120.Travel-Guide-Hotels) ## More cheap stays in San Isidro ![Brisas Hotel](https://images.trvl-media.com/lodging/36000000/35390000/35383700/35383677/490a2257_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Brisas Hotel clinica Santa Fe 75 varas este Matagalpa MATAGALPA CA $70 CA $81 total Dec 7 - Dec 8 includes taxes & fees 9.8/10 Exceptional! (12 reviews) [](https://expedia.ca/Matagalpa-Hotels-Brisas-Hotel.h35383677.Hotel-Information) ![Hotel Neblina](https://images.trvl-media.com/lodging/23000000/22360000/22354600/22354548/fd5c7d18_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Neblina Del Restaurante Tip Top 1 Cuadra Al Sur Jinotega Jinotega CA $55 CA $65 total Dec 15 - Dec 16 includes taxes & fees 8/10 Very Good! (6 reviews) [](https://expedia.ca/Jinotega-Hotels-Hotel-Neblina.h22354548.Hotel-Information) ![Vera Eco-Resort](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/0c38b01d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Vera Eco-Resort Vera Eco-Resort San Ramon Matagalpa CA $75 CA $103 total Dec 7 - Dec 8 includes taxes & fees 8/10 Very Good! (4 reviews) [](https://expedia.ca/San-Ramon-Hotels-Vera-Eco-Resort.h111250683.Hotel-Information) ![Hotel y Restaurante Las Orquídeas](https://images.trvl-media.com/lodging/24000000/23940000/23938900/23938819/d1fb7567_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel y Restaurante Las Orquídeas Costado sur parque municipal San Ramon Matagalpa [Get rates](https://expedia.ca/Hotel-Search?startDate=18%2F12%2F2025&endDate=19%2F12%2F2025&selected=23938819&PinnedHotelID=23938819&HadPinnedHotel=true®ionId=553248635975849120) 8/10 Very Good! (5 reviews) [](https://expedia.ca/San-Ramon-Hotels-Hotel-Y-Restaurante-Las-Orquideas.h23938819.Hotel-Information) ![Hotel Don Vito](https://images.trvl-media.com/lodging/32000000/31910000/31909000/31908922/5faae45b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Don Vito Parque Infantil 1 1/2 c. al Este. Esteli Departamento de Estelí [Get rates](https://expedia.ca/Hotel-Search?startDate=18%2F12%2F2025&endDate=19%2F12%2F2025&selected=31908922&PinnedHotelID=31908922&HadPinnedHotel=true®ionId=553248635975849120) [](https://expedia.ca/Esteli-Hotels-Hotel-Don-Vito.h31908922.Hotel-Information) ![Isabella House 54](https://images.trvl-media.com/lodging/121000000/120610000/120601800/120601746/180e8073_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Isabella House 54 Matagalpa Matagalpa CA $156 CA $184 total Dec 7 - Dec 8 includes taxes & fees [](https://expedia.ca/Matagalpa-Hotels-Vrbo-Property.h120601746.Hotel-Information) ## Recent reviews of San Isidro hotels ![Vera Eco-Resort](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/0c38b01d_y.jpg) ### Vera Eco-Resort 5/5 Excellent "This place is amazing!!!! The staff is super friendly and the location is beautiful " A verified traveller stayed at Vera Eco-Resort Posted 2 weeks ago [](https://expedia.ca/San-Ramon-Hotels-Vera-Eco-Resort.h111250683.Hotel-Information) ![Montebrisa Boutique B&B](https://images.trvl-media.com/lodging/37000000/36750000/36746300/36746289/61c163b4_y.jpg) ### Montebrisa Boutique B&B 5/5 Excellent "Clean rooms, friendly and attentive staff, safe and gated property, delicious breakfast and coffee. " A verified traveller stayed at Montebrisa Boutique B&B Posted 2 weeks ago [](https://expedia.ca/Matagalpa-Hotels-Montebrisa-Boutique-BB.h36746289.Hotel-Information) ![Casa Bonita Full](https://images.trvl-media.com/lodging/111000000/110620000/110616000/110615983/w390h700x320y0-3acb9b63_y.jpg) ### Casa Bonita Full 5/5 Excellent "Everything was first class. Host was very helpful, even replaced a bathroom sink I broke when I was trying to turn on shower heat and slipped and fell on sink. It was replaced the next day. Good people to deal with." A verified traveller stayed at Casa Bonita Full Posted 1 month ago [](https://expedia.ca/Matagalpa-Hotels-Casa-Bonita-Full.h110615983.Hotel-Information) ![Hotel Neblina](https://images.trvl-media.com/lodging/23000000/22360000/22354600/22354548/fd5c7d18_y.jpg) ### Hotel Neblina 4/5 Good "Hotel room was confortable, staff was excellent, breakfast delicious. " A verified traveller from Antioch stayed at Hotel Neblina Posted 2 months ago [](https://expedia.ca/Jinotega-Hotels-Hotel-Neblina.h22354548.Hotel-Information) ![H & R Ranch Resort ](https://images.trvl-media.com/lodging/96000000/95050000/95049000/95048999/w1640h1230x0y565-b8ca013c_y.jpg) ### H & R Ranch Resort 5/5 Excellent "Clean rooms, excellent staff, beautiful views! Tranquilo, Tranquilo!" A verified traveller stayed at H & R Ranch Resort Posted 2 months ago [](https://expedia.ca/Esteli-Hotels-H-R-Ranch-Resort.h95048999.Hotel-Information) ![Hotel Hex Esteli](https://images.trvl-media.com/lodging/7000000/6980000/6975400/6975392/416e82cc_y.jpg) ### Hotel Hex Esteli 5/5 Excellent "Clean room, good breakfast " A verified traveller stayed at Hotel Hex Esteli Posted 3 months ago [](https://expedia.ca/Esteli-Hotels-Hotel-Hex-Esteli.h6975392.Hotel-Information) ![Hotel Los Altos Esteli](https://images.trvl-media.com/lodging/11000000/10610000/10608200/10608128/5610bed5_y.jpg) ### Hotel Los Altos Esteli 5/5 Excellent "I would definitely stay here again! The staff was very nice, the room was clean with a comfortable bed, cold AC, and working TV. The shower had plenty of hot water. The breakfast was much appreciated. Overall, it had a quiet, intimate feel, great for families, couples, or individuals. Small, but clean and nice. 5/5" A verified traveller from North Charleston stayed at Hotel Los Altos Esteli Posted 5 months ago [](https://expedia.ca/Esteli-Hotels-Hotel-Los-Altos-Esteli.h10608128.Hotel-Information) ![Brisas Hotel](https://images.trvl-media.com/lodging/36000000/35390000/35383700/35383677/490a2257_y.jpg) ### Brisas Hotel 5/5 Excellent "Great hotel will return for a visit when back in matagalpa" A verified traveller stayed at Brisas Hotel Posted 9 months ago [](https://expedia.ca/Matagalpa-Hotels-Brisas-Hotel.h35383677.Hotel-Information) ## Frequently asked questions ### Where is the best place for a stay in San Isidro? ### What are some of the best vacation rentals in San Isidro? ### If I need to cancel my hotel reservation in San Isidro, will I receive a refund? ### What's it like to stay in San Isidro? ### What is there to see in San Isidro? ### What's the seasonal weather like in San Isidro? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Ciudad Dario Hotels ](https://www.expedia.ca/Ciudad-Dario-Hotels.d6351594.Travel-Guide-Hotels) - [Lgbt Friendly Hotels in Matagalpa Department ](https://www.expedia.ca/Destinations-In-Matagalpa-Department-LGBT-Friendly-Hotel.0-0-d6314196-tLGBTFriendlyHotel.Hotel-Filter-Destinations) - [Matagalpa Department Hotels ](https://www.expedia.ca/Destinations-In-Matagalpa-Department.d6314196.Hotel-Destinations) - [El Roblar Hotels ](https://www.expedia.ca/El-Roblar-Hotels.d6351146.Travel-Guide-Hotels) - [Esquipulas Hotels ](https://www.expedia.ca/Esquipulas-Hotels.d662833757924794368.Travel-Guide-Hotels) - [La Corona Hotels ](https://www.expedia.ca/La-Corona-Hotels.d6351143.Travel-Guide-Hotels) - [La Reina Hotels ](https://www.expedia.ca/La-Reina-Hotels.d6351148.Travel-Guide-Hotels) - [Matagalpa Hotels ](https://www.expedia.ca/Matagalpa-Hotels.d6053701.Travel-Guide-Hotels) - [San Ramon Hotels ](https://www.expedia.ca/San-Ramon-Hotels.d6351017.Travel-Guide-Hotels) - [Sebaco Hotels ](https://www.expedia.ca/Sebaco-Hotels.d6351019.Travel-Guide-Hotels) - [Terrabona Hotels ](https://www.expedia.ca/Terrabona-Hotels.d662833748170940416.Travel-Guide-Hotels) - [Flights to San Ramon ](https://www.expedia.ca/Cheap-Flights-To-San-Ramon.d6351017.Travel-Guide-Flights) - [Casa Museo Comandante Carlos Fonseca ](https://www.expedia.ca/Casa-Museo-Comandante-Carlos-Fonseca-Matagalpa.d553248621532964568.Vacation-Attraction) - [Visit Matagalpa ](https://www.expedia.ca/Matagalpa.dx6053701) - [Budget Rental Cars in Matagalpa ](https://www.expedia.ca/Budget-Car-Rentals-In-Matagalpa.d6053701-c39.Car-Rental-Guide-Suppliers) - [Car rental Matagalpa ](https://www.expedia.ca/Car-Rentals-In-Matagalpa.d6053701.Car-Rental-Guide) - [Matagalpa Department Vacation Rentals ](https://www.expedia.ca/Destinations-In-Matagalpa-Department.d6314196.Vacation-Rental-Destinations) - [Things to do in Matagalpa ](https://www.expedia.ca/Things-To-Do-In-Matagalpa.d6053701.Travel-Guide-Activities) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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