Title: Book The Best Hotels in San Isidro for 2026 from CA $69 - Fully Refundable Options - Expedia.ca [Vacation Rentals in San Isidro](https://expedia.ca/San-Isidro-Vacation-Rentals.d553248635975849120.Travel-Guide-VacationRentals)[San Isidro Car Rentals](https://expedia.ca/Car-Rentals-In-San-Isidro.d553248635975849120.Car-Rental-Guide)[San Isidro Vacation Packages](https://expedia.ca/San-Isidro.d553248635975849120.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in San Isidro Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=San+Isidro%2C+Matagalpa+Department%2C+Nicaragua®ionId=553248635975849120&latLong=12.867527%2C-86.217584&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&amenities=PETS) ## Check prices for these dates Tonight [Jan 18 - Jan 19](https://www.expedia.ca/Hotel-Search?regionId=553248635975849120&startDate=2026-01-18&endDate=2026-01-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 19 - Jan 20](https://www.expedia.ca/Hotel-Search?regionId=553248635975849120&startDate=2026-01-19&endDate=2026-01-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=553248635975849120&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248635975849120&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for San Isidro hotels ![Property entrance](https://images.trvl-media.com/lodging/7000000/6980000/6975400/6975392/0d3b0873.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/7000000/6980000/6975400/6975392/540e14a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/7000000/6980000/6975400/6975392/882d35f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/7000000/6980000/6975400/6975392/b5a2f2c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hex Esteli [](https://www.expedia.ca/Esteli-Hotels-Hotel-Hex-Esteli.h6975392.Hotel-Information) Esteli 8.4/10 Very good (193 reviews) "Excellent location, very friendly and helpful staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gustavo [](https://www.expedia.ca/Esteli-Hotels-Hotel-Hex-Esteli.h6975392.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/36000000/35390000/35383700/35383677/9454e921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 1 Double Bed](https://images.trvl-media.com/lodging/36000000/35390000/35383700/35383677/dccfa78c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/36000000/35390000/35383700/35383677/b4e2ddb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/36000000/35390000/35383700/35383677/490a2257.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Brisas Hotel [](https://www.expedia.ca/Matagalpa-Hotels-Brisas-Hotel.h35383677.Hotel-Information) Matagalpa 9.6/10 Exceptional (17 reviews) "Very nice accommodation, a good value, fríe staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $80 CA $92 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Matagalpa-Hotels-Brisas-Hotel.h35383677.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/37000000/36750000/36746300/36746289/485f5871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/37000000/36750000/36746300/36746289/9e44dd61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/37000000/36750000/36746300/36746289/4ab51a60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/37000000/36750000/36746300/36746289/f5a120c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Montebrisa Boutique B&B [](https://www.expedia.ca/Matagalpa-Hotels-Montebrisa-Boutique-BB.h36746289.Hotel-Information) Matagalpa 9.0/10 Wonderful (43 reviews) "Parking waa easy and very safe. Breakfast was outstanding with excellent service!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Igor CA $125 CA $144 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/Matagalpa-Hotels-Montebrisa-Boutique-BB.h36746289.Hotel-Information) ![Deluxe Cabin](https://images.trvl-media.com/lodging/96000000/95050000/95049000/95048999/25b1edf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/96000000/95050000/95049000/95048999/bdf03e75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Studio Suite, 2 Bedrooms | Bathroom](https://images.trvl-media.com/lodging/96000000/95050000/95049000/95048999/w1640h1230x0y565-74ca64f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Studio Suite, 2 Bedrooms | Living area](https://images.trvl-media.com/lodging/96000000/95050000/95049000/95048999/de0bf87d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### H & R Ranch Resort [](https://www.expedia.ca/Esteli-Hotels-H-R-Ranch-Resort.h95048999.Hotel-Information) Esteli 8.2/10 Very good (27 reviews) "It was the most peaceful time I’ve ever had. Loved the staff and place was just amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arllen CA $116 CA $134 total includes taxes & fees Jan 24 - Jan 25 [](https://www.expedia.ca/Esteli-Hotels-H-R-Ranch-Resort.h95048999.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/75b5851e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/aef1bb54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/5725a167.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Villa, 2 Bedrooms, Kitchen, Mountain View | Terrace/patio](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/17ac001e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vera Eco-Resort [](https://www.expedia.ca/San-Ramon-Hotels-Vera-Eco-Resort.h111250683.Hotel-Information) San Ramon 8.0/10 Very good (4 reviews) "Had an excellent week at the resort. If you need a quiet, relaxing break this is the place to go. There are several kilometers of hiking trails. You can also do horseback riding and be guided through the coffee making process. The rooms are comfortable and clean. Hot water is dependable. Most units have amazing views. The staff are eager to help you enjoy your stay. Especially Stanley, who is a master at the hospitality profession." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $81 CA $110 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/San-Ramon-Hotels-Vera-Eco-Resort.h111250683.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/23000000/22360000/22354600/22354548/fd5c7d18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/23000000/22360000/22354600/22354548/bf96ce6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/23000000/22360000/22354600/22354548/b2250537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/23000000/22360000/22354600/22354548/63db17e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Neblina [](https://www.expedia.ca/Jinotega-Hotels-Hotel-Neblina.h22354548.Hotel-Information) Jinotega 7.2/10 Good (7 reviews) "Hotel room was confortable, staff was excellent, breakfast delicious. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Salvador CA $60 CA $69 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/Jinotega-Hotels-Hotel-Neblina.h22354548.Hotel-Information) ![Standard Double Room, Mountain View | Living area](https://images.trvl-media.com/lodging/125000000/124520000/124519000/124518912/4f0237c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, Mountain View](https://images.trvl-media.com/lodging/125000000/124520000/124519000/124518912/4b9d8a54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily local cuisine breakfast](https://images.trvl-media.com/lodging/125000000/124520000/124519000/124518912/f50a7fe3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, Mountain View](https://images.trvl-media.com/lodging/125000000/124520000/124519000/124518912/43f161a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Vizcaino [](https://www.expedia.ca/Matagalpa-Hotels-Hotel-Vizcaino.h124518912.Hotel-Information) Matagalpa CA $79 CA $92 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/Matagalpa-Hotels-Hotel-Vizcaino.h124518912.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-01&endDate=2026-02-02®ionId=553248635975849120&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSan-Isidro-Hotels.d553248635975849120.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSan-Isidro-Hotels.d553248635975849120.Travel-Guide-Hotels) ## More cheap stays in San Isidro ![Hotel Neblina](https://images.trvl-media.com/lodging/23000000/22360000/22354600/22354548/fd5c7d18_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Neblina Del Restaurante Tip Top 1 Cuadra Al Sur Jinotega Jinotega CA $60 CA $69 total Jan 19 - Jan 20 includes taxes & fees 8/10 Very Good! (6 reviews) [](https://expedia.ca/Jinotega-Hotels-Hotel-Neblina.h22354548.Hotel-Information) ![Brisas Hotel](https://images.trvl-media.com/lodging/36000000/35390000/35383700/35383677/490a2257_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Brisas Hotel clinica Santa Fe 75 varas este Matagalpa MATAGALPA CA $80 CA $92 total Jan 21 - Jan 22 includes taxes & fees 9.6/10 Exceptional! (17 reviews) [](https://expedia.ca/Matagalpa-Hotels-Brisas-Hotel.h35383677.Hotel-Information) ![Vera Eco-Resort](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/0c38b01d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Vera Eco-Resort Vera Eco-Resort San Ramon Matagalpa CA $81 CA $110 total Jan 19 - Jan 20 includes taxes & fees 8/10 Very Good! (4 reviews) [](https://expedia.ca/San-Ramon-Hotels-Vera-Eco-Resort.h111250683.Hotel-Information) ![Hotel y Restaurante Las Orquídeas](https://images.trvl-media.com/lodging/24000000/23940000/23938900/23938819/d1fb7567_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel y Restaurante Las Orquídeas Costado sur parque municipal San Ramon Matagalpa [Get rates](https://expedia.ca/Hotel-Search?startDate=01%2F02%2F2026&endDate=02%2F02%2F2026&selected=23938819&PinnedHotelID=23938819&HadPinnedHotel=true®ionId=553248635975849120) 8/10 Very Good! (5 reviews) [](https://expedia.ca/San-Ramon-Hotels-Hotel-Y-Restaurante-Las-Orquideas.h23938819.Hotel-Information) ![Hotel Don Vito](https://images.trvl-media.com/lodging/32000000/31910000/31909000/31908922/5faae45b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Don Vito Parque Infantil 1 1/2 c. al Este. Esteli Departamento de Estelí [Get rates](https://expedia.ca/Hotel-Search?startDate=01%2F02%2F2026&endDate=02%2F02%2F2026&selected=31908922&PinnedHotelID=31908922&HadPinnedHotel=true®ionId=553248635975849120) [](https://expedia.ca/Esteli-Hotels-Hotel-Don-Vito.h31908922.Hotel-Information) ![Hotel Casa Vinculos](https://images.trvl-media.com/lodging/37000000/36810000/36800500/36800438/32558ef9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Casa Vinculos Almacen Sony 1.5 cuadra al oeste Esteli Esteli [Get rates](https://expedia.ca/Hotel-Search?startDate=01%2F02%2F2026&endDate=02%2F02%2F2026&selected=36800438&PinnedHotelID=36800438&HadPinnedHotel=true®ionId=553248635975849120) [](https://expedia.ca/Esteli-Hotels-Hotel-Casa-Vinculos.h36800438.Hotel-Information) ## Recent reviews of San Isidro hotels ![Hotel Hex Esteli](https://images.trvl-media.com/lodging/7000000/6980000/6975400/6975392/416e82cc_y.jpg) ### Hotel Hex Esteli 5/5 Excellent "Great staff, good service, very professional" A verified traveller stayed at Hotel Hex Esteli Posted 5 days ago [](https://expedia.ca/Esteli-Hotels-Hotel-Hex-Esteli.h6975392.Hotel-Information) ![Brisas Hotel](https://images.trvl-media.com/lodging/36000000/35390000/35383700/35383677/490a2257_y.jpg) ### Brisas Hotel 5/5 Excellent "Staff! Alfredo was an excellent host. Took care of us and made us feel at home." A verified traveller stayed at Brisas Hotel Posted 2 weeks ago [](https://expedia.ca/Matagalpa-Hotels-Brisas-Hotel.h35383677.Hotel-Information) ![Hotel Los Altos Esteli](https://images.trvl-media.com/lodging/11000000/10610000/10608200/10608128/5610bed5_y.jpg) ### Hotel Los Altos Esteli 5/5 Excellent "personnel aimable, localisation parfaite " A verified traveller stayed at Hotel Los Altos Esteli Posted 3 weeks ago [](https://expedia.ca/Esteli-Hotels-Hotel-Los-Altos-Esteli.h10608128.Hotel-Information) ![H & R Ranch Resort ](https://images.trvl-media.com/lodging/96000000/95050000/95049000/95048999/w1640h1230x0y565-b8ca013c_y.jpg) ### H & R Ranch Resort 5/5 Excellent "It was the most peaceful time I’ve ever had. Loved the staff and place was just amazing. " A verified traveller stayed at H & R Ranch Resort Posted 3 weeks ago [](https://expedia.ca/Esteli-Hotels-H-R-Ranch-Resort.h95048999.Hotel-Information) ![Montebrisa Boutique B&B](https://images.trvl-media.com/lodging/37000000/36750000/36746300/36746289/61c163b4_y.jpg) ### Montebrisa Boutique B&B 5/5 Excellent "Beautiful hotel with excellent rooms and service " A verified traveller stayed at Montebrisa Boutique B&B Posted 3 weeks ago [](https://expedia.ca/Matagalpa-Hotels-Montebrisa-Boutique-BB.h36746289.Hotel-Information) ![Vera Eco-Resort](https://images.trvl-media.com/lodging/112000000/111260000/111250700/111250683/0c38b01d_y.jpg) ### Vera Eco-Resort 5/5 Excellent "This place is amazing!!!! The staff is super friendly and the location is beautiful " A verified traveller stayed at Vera Eco-Resort Posted 2 months ago [](https://expedia.ca/San-Ramon-Hotels-Vera-Eco-Resort.h111250683.Hotel-Information) ![Hotel Neblina](https://images.trvl-media.com/lodging/23000000/22360000/22354600/22354548/fd5c7d18_y.jpg) ### Hotel Neblina 4/5 Good "Hotel room was confortable, staff was excellent, breakfast delicious. " A verified traveller from Antioch stayed at Hotel Neblina Posted 3 months ago [](https://expedia.ca/Jinotega-Hotels-Hotel-Neblina.h22354548.Hotel-Information) ![Hotel y Restaurante Las Orquídeas](https://images.trvl-media.com/lodging/24000000/23940000/23938900/23938819/d1fb7567_y.jpg) ### Hotel y Restaurante Las Orquídeas 3/5 Okay "Beautiful hotel but over price for what you receive. You get breakfast, but have to order the night before. You have to ask in advance for hot water to be turned on. The first few days, the doors would be locked and you would have to find the desk attendant to let you out or in. Many time we had to wait until he showed up. Finaly we convinced him to just leave it open for us. In my room, the AC broke down twice and had to be fixed, which admittedly they did right away both times. Attendant was super friendly though and tried to accommodate us. Laundry is available on request. The nieghborhood, is fairly clean for a developing country, but the noise from the trucks driving close by could be unbearable sometimes as they use their retarder breaks in the city. " A verified traveller stayed at Hotel y Restaurante Las Orquídeas Posted 1 year ago [](https://expedia.ca/San-Ramon-Hotels-Hotel-Y-Restaurante-Las-Orquideas.h23938819.Hotel-Information) ## Frequently asked questions ### Where is the best place for a stay in San Isidro? ### What are some of the best vacation rentals in San Isidro? ### If I need to cancel my hotel reservation in San Isidro, will I receive a refund? ### What's it like to stay in San Isidro? ### What is there to see in San Isidro? ### What's the seasonal weather like in San Isidro? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Ciudad Dario Hotels ](https://www.expedia.ca/Ciudad-Dario-Hotels.d6351594.Travel-Guide-Hotels) - [Lgbt Friendly Hotels in Matagalpa Department ](https://www.expedia.ca/Destinations-In-Matagalpa-Department-LGBT-Friendly-Hotel.0-0-d6314196-tLGBTFriendlyHotel.Hotel-Filter-Destinations) - [Matagalpa Department Hotels ](https://www.expedia.ca/Destinations-In-Matagalpa-Department.d6314196.Hotel-Destinations) - [El Roblar Hotels ](https://www.expedia.ca/El-Roblar-Hotels.d6351146.Travel-Guide-Hotels) - [Esquipulas Hotels ](https://www.expedia.ca/Esquipulas-Hotels.d662833757924794368.Travel-Guide-Hotels) - [La Corona Hotels ](https://www.expedia.ca/La-Corona-Hotels.d6351143.Travel-Guide-Hotels) - [La Reina Hotels ](https://www.expedia.ca/La-Reina-Hotels.d6351148.Travel-Guide-Hotels) - [Matagalpa Hotels ](https://www.expedia.ca/Matagalpa-Hotels.d6053701.Travel-Guide-Hotels) - [San Ramon Hotels ](https://www.expedia.ca/San-Ramon-Hotels.d6351017.Travel-Guide-Hotels) - [Sebaco Hotels ](https://www.expedia.ca/Sebaco-Hotels.d6351019.Travel-Guide-Hotels) - [Terrabona Hotels ](https://www.expedia.ca/Terrabona-Hotels.d662833748170940416.Travel-Guide-Hotels) - [Flights to San Ramon ](https://www.expedia.ca/Cheap-Flights-To-San-Ramon.d6351017.Travel-Guide-Flights) - [Casa Museo Comandante Carlos Fonseca ](https://www.expedia.ca/Casa-Museo-Comandante-Carlos-Fonseca-Matagalpa.d553248621532964568.Vacation-Attraction) - [Visit Matagalpa ](https://www.expedia.ca/Matagalpa.dx6053701) - [Budget Rental Cars in Matagalpa ](https://www.expedia.ca/Budget-Car-Rentals-In-Matagalpa.d6053701-c39.Car-Rental-Guide-Suppliers) - [Car rental Matagalpa ](https://www.expedia.ca/Car-Rentals-In-Matagalpa.d6053701.Car-Rental-Guide) - [Matagalpa Department Vacation Rentals ](https://www.expedia.ca/Destinations-In-Matagalpa-Department.d6314196.Vacation-Rental-Destinations) - [Things to do in Matagalpa ](https://www.expedia.ca/Things-To-Do-In-Matagalpa.d6053701.Travel-Guide-Activities) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app