Midtown
St. Louis
Visit Midtown
Stay near popular Midtown attractions
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
CA $34
per adult
100% of travellers recommend
StL's Signature "Sights and Bites" - Private Tour in St. Louis
CA $247
per adult
Lemp Haunted Neighborhood Walking Tour
CA $35
per adult
84% of travellers recommend
Dinner Detective True Crime Murder Mystery Show - St. Louis, MO
CA $126
per adult
St. Louis Burlesque & Nightlife Experience at The Boom Boom Room
CA $85
per adult
100% of travellers recommend
Midtown Hotel Deals
Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
The price is CA $126 per night from Oct 30 to Oct 31
CA $126
CA $150 total
Oct 30 - Oct 31
includes taxes & fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (3,326 reviews)
"We purposely picked this hotel because it was in our budget and handicapped accessible rooms and bathrooms. Our bathroom was not handicappes accessible. This means that my husband took a sponge bath instead of a shower. He wasn't thrilled and I wasn't happy either."
Reviewed on Oct 25, 2026
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
The price is CA $202 per night from Nov 1 to Nov 2
CA $202
CA $236 total
Nov 1 - Nov 2
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.6/10 Exceptional! (3,810 reviews)
"Staff was super nice and helpful. Breakfast was great and happy hour was a pleasant surprise"
Reviewed on Oct 25, 2026
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
The price is CA $175 per night from Nov 25 to Nov 26
CA $175
CA $207 total
Nov 25 - Nov 26
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,380 reviews)
"Very nice. I’ll be back. Celebrities and everythin"
Reviewed on Oct 25, 2026
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
The price is CA $131 per night from Nov 1 to Nov 2
CA $131
CA $153 total
Nov 1 - Nov 2
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (3,514 reviews)
"Even though most of the reviews were great, I was still skeptical because I've had a horrible experience at a highly rated hotel. I must say, the people were telling the truth! The staff was super nice, and the rooms were cleaned. I especially like being able to control the shower temperature digitally. ..."
Reviewed on Oct 26, 2026
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
The price is CA $132 per night from Nov 1 to Nov 2
CA $132
CA $176 total
Nov 1 - Nov 2
includes taxes & fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (2,237 reviews)
"Stayed 1 night for a concert. Typical charges for parking and amenities which will be extra. Walking isn't very friendly to amphitheater even though it's in the same area, would take 30 minutes and not a designated walking area for it. Basically you pay parking twice either for a shuttle or driving ..."
Reviewed on Oct 25, 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
The price is CA $145 per night from Nov 22 to Nov 23
CA $145
CA $171 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Midtown
Find the best Midtown areas and neighborhoods for the activities you enjoy most.
Downtown St. Louis
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.
Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
St. Charles Historic District
St. Charles Historic District is known for its abundant dining options, and you can plan a trip to Historic Main Street and Missouri River while you're in town.
Central West End
The ample dining options and lush forests are just a few popular features of the neighborhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
