Midtown Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Holiday Package Deals in Midtown

Price found within the past 48 hours. Click for updated prices.
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

Riverport
CA $1,487
per person
Nov 25 - Dec 2
found 23 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
8.6/10 Excellent! (2,245 reviews)
The Wildwood Hotel

The Wildwood Hotel

CA $1,619
per person
Nov 25 - Dec 2
found 23 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
9.2/10 Wonderful! (1,679 reviews)
Hermann Grain Bins BNB

Hermann Grain Bins BNB

Save 100% on your flight
CA $2,191
per person
Nov 25 - Dec 1
found 1 day ago
Roundtrip non-stop flight included
Vancouver (YVR) to St. Louis (STL)
6/10 (2 reviews)
It was so comfortable and uniquely and beautifully decorated! There was so many awesome areas to explore inside and outside of the Grain Bins. Food provided for breakfast was fresh and hot. There was perfectly cooked bacon, scrambled eggs and really moist corn muffins with homemade mango preservers! We were welcomed with fresh, homemade plum bread. Instructions for everything available to utilize and operate were easy to understand. I can’t wait to go back and I will tell all my friends and family about this unique and relaxing place.

Reviewed on May 22, 2026

The Cheshire

The Cheshire

CA $1,905
per person
Nov 25 - Dec 2
found 23 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
8.8/10 Excellent! (1,011 reviews)
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

Midtown
CA $1,535
per person
Nov 25 - Dec 2
found 23 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
7.6/10 Good! (1,000 reviews)

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most. Learn more about Midtown
A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Downtown St. Louis

4 out of top 10 points of interest in this area

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

The illuminated Gateway Arch at night with a city skyline in the background.

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

A street with parked cars, a building with a sign reading "Brennan's", and a tree in front.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Midtown Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
CA $131
CA $153 total
Nov 1 - Nov 2
includes taxes & fees
8.8/10 Excellent! (3,488 reviews)
"Location is great, safe, quiet, great restaurants, close to all St. Louis has to offer. The hotel was top notch. Good value for the money."

Reviewed on Oct 16, 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
CA $126
CA $149 total
Oct 22 - Oct 23
includes taxes & fees
Pear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
CA $191
CA $223 total
Nov 17 - Nov 18
includes taxes & fees
9.6/10 Exceptional! (3,782 reviews)
"Loved the breakfast buffet, the dinner buffet and the cocktails. It was like being in an exclusive place, in a secure area."

Reviewed on Oct 16, 2026

Drury Plaza Hotel St. Louis at the Arch
See all 1,967 properties in Midtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Midtown vacation package cost?
Starting from a low CA $1,487, a package is your gateway to low-priced travel. Build your own Midtown trip by selecting from our great range of hotels, flights and rental cars.
How do I get a cheap travel package to Midtown?
Bundle your bookings with Expedia to save big bucks on your next trip. With over 550 partner airlines and 1,000,000 properties throughout the world, your Midtown vacation package can be tailored exactly to suit your travel style. With all that extra cash, why not add one or two awesome tours and activities? It's an easy way to unlock even more savings. The vacation you've always dreamed of in Midtown is much closer than you thought!
Where should I stay in Midtown?
A trip to Midtown isn't complete until you've seen Busch Stadium and Gateway Arch. Book a hotel within walking distance so you can easily access these terrific tourist attractions.
What are the top hotels in Midtown?
Book a room at Element St. Louis Midtown. It's one of this neighborhood's most in-demand hotels. Another reputable option in Midtown is Residence Inn by Marriott St Louis Downtown.
How far in advance should I book my Midtown vacation?
While prices fluctuate, we generally advise booking your vacation as soon as possible. Most international fares are available on Expedia up to 12 months in advance. If you're booking late, you might still get lucky. Cheap journeys to Midtown occasionally appear only weeks before departure.
What does an Expedia Midtown travel package include?
With Expedia, you can select a combination of car rentals, hotels and flights to build your ideal Midtown package. Once you've made your booking, you can add on the fun things like tours and experiences. Remember — the more you bundle, the bigger the savings!
What should I know before booking a Midtown travel package?
You'll land big savings when you bundle your hotels, flights and rental cars into a package. Plus, booking everything in one spot makes trip planning easier. So why waste time or money? Whether you're putting together an upscale romantic escape or an affordable family break, browse our vacation packages today.
Can I choose my airline with a Midtown Expedia vacation package?
With a vacation package, you're the boss. Whether you're looking to fly to Midtown in economy or business class, simply select from the available airline options. Expedia has access to over 550 airline partners worldwide.
If I'm not able to travel, can I cancel my Midtown vacation package?
Don't stress if you're rethinking your Midtown vacation package — it's possible to cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur charges from your airline, hotel or car rental company. We understand life can occasionally throw a spanner in the travel works, so head to our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.

Stay near popular Midtown attractions

A historic building with a large lawn, a flagpole with flags, and a clear blue sky.

St. Louis University

8.6/10 (526 reviews)
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theater scene.
See properties
A room with a grand piano, a white door, and a framed picture on the wall.
Photo by Wanderlustfemale

Scott Joplin House State Historic Site

Learn about the local history of St. Louis when you spend time at Scott Joplin House State Historic Site. Experience the area's fascinating museums or attend a baseball game.
See properties

Chaifetz Arena

8.8/10 (59 reviews)
Catch an event at Chaifetz Arena during your trip to St. Louis. Amble around the area's picturesque gardens or attend a baseball game.
See properties

Harris-Stowe State University

Explore the campus of Harris-Stowe State University during your visit to St. Louis.
See properties

Fubar

Fubar is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?
See properties

Samuel Cupples House

You can learn about the history of St. Louis with a stop at Samuel Cupples House. Experience the area's acclaimed theater scene or attend a sporting event.
See properties

Red Flag

You can enjoy a show at Red Flag on your trip to St. Louis.
See properties

City Foundry STL

City Foundry STL is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?
See properties

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

CA $34
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
The Gateway Arch National Park & Museum

StL's Signature "Sights and Bites" - Private Tour in St. Louis

CA $245
per adult
StL's Signature "Sights and Bites" - Private Tour in St. Louis
Lemp Haunted Neighborhood Walking Tour

Lemp Haunted Neighborhood Walking Tour

CA $35
per adult
84% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.