Maryville Vacation Packages

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Your Maryville Vacation

From its lively atmosphere to its spectacular views and beyond, there's plenty to love about Maryville. Uncover the delights of this awesome city with a Maryville vacation package that's made for you. A trip to Maryville is a wonderful opportunity to do a bit of sightseeing. Be sure to look around well-known attractions like Edwardsville Arts Center, Horseshoe Lake State Park and Villa Marie Winery & Banquet Center. Stop daydreaming and start traveling. Explore the multitude of options on Expedia today and finally put your Maryville vacation plans into motion!

Top Maryville Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Indigo St Louis - Central West End by IHG
The Wildwood Hotel
Hotel Saint Louis, Autograph Collection
Hilton Garden Inn St. Louis/O'Fallon MO
The Knight Center at Washington University

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

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Maryville Hotel Deals

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $182 per night from Feb 22 to Feb 23
CA $182
CA $219 total
Feb 22 - Feb 23
includes taxes & fees
9/10 Wonderful! (1,601 reviews)
We loved this hotel. It is something you expect in much more sophisticated cities but not St. Louis. Our king bed suite was tastefully furnished and very large. Lots of great touches and very clean. The lobby and museum were stylish and exciting. We ate at both Idolwolf and the cafe. Again great ...

Reviewed on Feb 8, 2026

21C Museum Hotel St Louis
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $175 per night from Feb 28 to Mar 1
CA $175
CA $206 total
Feb 28 - Mar 1
includes taxes & fees
8.4/10 Very Good! (4,012 reviews)
The first room we got was not the cleanliest and was really rundown. So we called down to the front desk and got a second room, which was much better and you could tell was remodeled in the bathroom. Smelled clean, looked clean unlike first room.

Reviewed on Feb 11, 2026

Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $195 per night from Feb 16 to Feb 17
CA $195
CA $228 total
Feb 16 - Feb 17
includes taxes & fees
9.4/10 Exceptional! (3,328 reviews)
Great room, great service, and the complimentary breakfast, drinks and dinner

Reviewed on Feb 9, 2026

Drury Plaza Hotel St. Louis at the Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.