Liam Maguire's Irish Pub & Restaurant with outdoor seating and flower pots.

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Our top choices for Main Street hotels

1. Hyannis Travel Inn

Hyannis Travel Inn
2.5 star property
9.1 km from Main Street
9.6 out of 10, Exceptional, (1,037 reviews)
"Great property, convenient location and helpful staff."
United States
Colleen
The price is CA $130
CA $149 total
includes taxes & fees
Nov 10 - Nov 11
Hyannis Travel Inn

2. Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
3.0 star property
9.1 km from Main Street
8.8 out of 10, Excellent, (761 reviews)
"Its in a great location"
United States
Estefany
The price is CA $179
CA $205 total
includes taxes & fees
Nov 16 - Nov 17
Fairfield Inn & Suites by Marriott Cape Cod Hyannis

3. Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
4.0 star property
10.9 km from Main Street
9.2 out of 10, Wonderful, (418 reviews)
"beautiful and fun property!"
United States
Jen
The price is CA $147
CA $174 total
includes taxes & fees
Dec 1 - Dec 2
Uncommoner Hotel by Reverie Boutique Collection

4. The Escape Inn

The Escape Inn
2.5 star property
16.5 km from Main Street
9.4 out of 10, Exceptional, (813 reviews)
"Very clean room, easy to check in and great breakfast!"
United States
Marcegui
The price is CA $120
CA $138 total
includes taxes & fees
Nov 10 - Nov 11
The Escape Inn

5. Holiday Inn Express Hyannis Cape Cod by IHG

Holiday Inn Express Hyannis Cape Cod by IHG
2.5 star property
8.8 km from Main Street
8.8 out of 10, Excellent, (157 reviews)
"The best option in Hyannis, comfortable room and amazing breakfast"
United States
Silvia
The price is CA $120
CA $137 total
includes taxes & fees
Dec 7 - Dec 8
Holiday Inn Express Hyannis Cape Cod by IHG

6. The Club at New Seabury

The Club at New Seabury
3.5 star property
10.3 km from Main Street
9.0 out of 10, Wonderful, (372 reviews)
"The New Seabury resort is beautiful & has excellent customer service. The 4/5 stars is because the unit we stayed in needs some updating. However, the layout, cleanliness, & location is good."
United States
Kathleen
The price is CA $208
CA $238 total
includes taxes & fees
Nov 10 - Nov 11
The Club at New Seabury

7. Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
9.2 km from Main Street
8.8 out of 10, Excellent, (519 reviews)
"Location was good and relaxing"
United States
SHREYASI
The price is CA $179
CA $205 total
includes taxes & fees
Nov 16 - Nov 17
Courtyard By Marriott Cape Cod Hyannis

8. Blue Lobster Inn

Blue Lobster Inn
2.0 star property
13.9 km from Main Street
9.6 out of 10, Exceptional, (10 reviews)
"Everything was so clean and new yet vintage and rustic. The bed was so comfortable and staff was so kind"
United States
Jonathan
The price is CA $137
CA $157 total
includes taxes & fees
Nov 12 - Nov 13
Blue Lobster Inn

9. Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
11.2 km from Main Street
8.8 out of 10, Excellent, (1,585 reviews)
"Nice and clean hotel. Kind and helpful staff."
Italy
Michela
The price is CA $127
CA $165 total
includes taxes & fees
Nov 15 - Nov 16
Bayside Resort Hotel

10. Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
10.7 km from Main Street
8.8 out of 10, Excellent, (1,003 reviews)
"Great place to stay great location nice pool and hot tub great breakfast bar"
United States
Paul
The price is CA $149
CA $170 total
includes taxes & fees
Dec 10 - Dec 11
Hampton Inn & Suites Cape Cod-West Yarmouth

11. The Cove at Yarmouth by Westgate Resorts

The Cove at Yarmouth by Westgate Resorts
3.0 star property
11.2 km from Main Street
9.2 out of 10, Wonderful, (273 reviews)
"Everything was great. Very clean room"
United States
Manizheh
The price is CA $152
CA $174 total
includes taxes & fees
Nov 10 - Nov 11
The Cove at Yarmouth by Westgate Resorts

12. Cape Sands Inn

Cape Sands Inn
2.5 star property
11 km from Main Street
8.2 out of 10, Very good, (1,162 reviews)
"Staff was excellent hotel clean"
United States
Jerome
The price is CA $97
CA $111 total
includes taxes & fees
Nov 10 - Nov 11
Cape Sands Inn

13. Ocean Club on Smuggler's Beach

Ocean Club on Smuggler's Beach
2.5 star property
15.3 km from Main Street
9.2 out of 10, Wonderful, (1,005 reviews)
"Had great views of the ocean from the room. Lots of beach to explore. Loved how the room was setup and decorated."
United States
Jean
The price is CA $189
CA $232 total
includes taxes & fees
Nov 10 - Nov 11
Ocean Club on Smuggler's Beach

14. Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
9.4 km from Main Street
8.2 out of 10, Very good, (1,002 reviews)
"It was an excellant hotel. The breakfast was outstanding."
United States
Paul
The price is CA $131
CA $150 total
includes taxes & fees
Nov 29 - Nov 30
Comfort Inn Hyannis - Cape Cod

15. Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
9.6 km from Main Street
9.4 out of 10, Exceptional, (1,006 reviews)
"Very nice stay with everything we needed. Excellent attention to detail. Great breakfast."
United States
Anita
The price is CA $189
CA $257 total
includes taxes & fees
Nov 10 - Nov 11
Anchor In Distinctive Waterfront Lodging

16. Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
8.9 km from Main Street
8.2 out of 10, Very good, (1,003 reviews)
"Great stay all around !"
United States
Alexander
The price is CA $167
CA $191 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Hyannis by IHG

17. Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
9.3 km from Main Street
9.0 out of 10, Wonderful, (201 reviews)
"Very nice place and great location to explore the town."
United States
Holly
The price is CA $155
CA $177 total
includes taxes & fees
Nov 29 - Nov 30
Heritage House Inn on Cape Cod, an Ascend Collection Hotel

18. Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
9.8 km from Main Street
8.4 out of 10, Very good, (954 reviews)
"Great stay"
Canada
Tammie
The price is CA $179
CA $205 total
includes taxes & fees
Nov 16 - Nov 17
Doubletree by Hilton Cape Cod - Hyannis

19. Chatham Tides

Chatham Tides
2.5 star property
29.5 km from Main Street
9.4 out of 10, Exceptional, (804 reviews)
"Beautiful room, location and staff"
United States
Robert
The price is CA $228
CA $261 total
includes taxes & fees
Nov 11 - Nov 12
Chatham Tides

20. The Ocean View

The Ocean View
2.5 star property
4.3 km from Main Street
9.2 out of 10, Wonderful, (161 reviews)
"We came in the off season and even without staff always present we were well taken care of."
United States
Regina
The price is CA $226
CA $258 total
includes taxes & fees
Nov 10 - Nov 11
The Ocean View
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Main Street

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A man sitting at a table with a laptop, overlooking a pool area with chairs and tables.
Hyannis Travel Inn
2.5 star property
9.6
Exceptional
1,037 reviews
View
A modern conference room with a long table, chairs, a flat-screen TV, and pendant lighting.
Fairfield Inn & Suites by Marriott Cape Cod Hyannis
3.0 star property
8.8
Excellent
761 reviews
View
A restaurant with outdoor seating, string lights, and a decorative wall.
Uncommoner Hotel by Reverie Boutique Collection
4.0 star property
9.2
Wonderful
418 reviews
View
A hotel with a white facade, a covered outdoor seating area with white chairs and tables, and a view of the sunset.
The Escape Inn
2.5 star property
9.4
Exceptional
813 reviews
View
An indoor swimming pool with lounge chairs and tables, a tiled wall, and a ceiling with recessed lighting.
Holiday Inn Express Hyannis Cape Cod by IHG
2.5 star property
8.8
Excellent
157 reviews
View

Top Main Street Hotel Reviews

Other attractions near Main Street

Frequently asked questions

What's the area like around Main Street?
If you're planning to come to the area to visit Main Street, take some time to see the rest of the sights while you're in town. If you're looking for a convenient place to stay, check out the 25 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Main Street?
Located 2.6 mi (4.3 km) from Main Street, The Ocean View is one of the top choices for your stay based on our traveler data. Another good option is Craigville Beach Inn, located 2.7 mi (4.3 km) away.
How many hotels will I find near Main Street?
Expedia has 25 hotels and other accommodations within a mile from Main Street.
If I need to cancel the hotel reservation for my stay near Main Street, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the top deals on offer near Main Street.
What can I see and do near Main Street?
Study the collections at Centerville Historical Museum, Cahoon Museum of American Art, or Toad Hall Classic Sports Car Museum. You can enjoy live performances at Cape Cod Melody Tent and Cotuit Center for the Arts. Dip your toes in the water at Craigville Beach, Dowses Beach, and Loop Beach.

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