A marshy landscape with water, trees, and a distant city skyline.

Ladys Island Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Ladys Island Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Jan 7 - Jan 12

    The Ryder Hotel + Flight

    Charleston Historic District
    5 nights
    3.5 star property
    8.8/10 - Excellent (1,264 reviews)
    Roundtrip • Detroit (DTW) - Charleston (CHS)
    DTW - CHS • Nonstop CHS - DTW • Nonstop
    CA $1,479
    CA $1,015
    per traveller
    found 1 day ago
    The Ryder Hotel
  • Jan 7 - Jan 12

    The Francis Marion Hotel + Flight

    Charleston Historic District
    5 nights
    4.0 star property
    9.0/10 - Wonderful (2,648 reviews)
    Roundtrip • Detroit (DTW) - Charleston (CHS)
    DTW - CHS • Nonstop CHS - DTW • Nonstop
    CA $1,609
    CA $1,161
    per traveller
    found 1 day ago
    The Francis Marion Hotel
  • Jan 7 - Jan 12

    The Pinch Hotel + Flight

    Charleston Historic District
    5 nights
    4.0 star property
    9.8/10 - Exceptional (217 reviews)
    "It’s just the best of the best"
    Reviewed November 6, 2026
    Roundtrip • Detroit (DTW) - Charleston (CHS)
    DTW - CHS • Nonstop CHS - DTW • Nonstop
    CA $1,917
    CA $1,504
    per traveller
    found 1 day ago
    The Pinch Hotel
  • Jan 7 - Jan 12

    Emeline + Flight

    Charleston Historic District
    5 nights
    4.0 star property
    9.4/10 - Exceptional (1,803 reviews)
    "I would definitely stay there again. It was very quiet in my room."
    Reviewed November 12, 2026
    Roundtrip • Detroit (DTW) - Charleston (CHS)
    DTW - CHS • Nonstop CHS - DTW • Nonstop
    CA $1,363
    CA $1,074
    per traveller
    found 1 day ago
    Emeline
  • Jan 7 - Jan 12

    Sparrow Haus by Avantstay Luxe Isle of Palms Retreat Pool + Firepit + Outdoor Lounge + Flight

    Isle of Palms
    5 nights
    3.0 star property
    Roundtrip • Detroit (DTW) - Charleston (CHS)
    DTW - CHS • Nonstop CHS - DTW • Nonstop
    CA $3,934
    CA $3,127
    per traveller
    found 18 hours ago
    Sparrow Haus by Avantstay Luxe Isle of Palms Retreat Pool + Firepit + Outdoor Lounge

Discover the most popular places to visit in Ladys Island

Ladys Island Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

How much does a Ladys Island vacation package cost?

The most affordable Ladys Island package is CA $1,015, so your dream getaway can become a reality — without it costing a fortune. Combine flights, hotels, car rentals and more to custom build a package that matches your traveling style.

How do I get a cheap travel package to Ladys Island?

Our Ladys Island vacation packages promise plenty of savings for the savvy traveler. For the best deals, simply bundle your flights, hotels and extras (including activities) into a neat and tidy package. But impressive bargains are only the start of your next amazing adventure. Book with Expedia and and you'll have over 550 airlines and 1,000,000 hotels globally to choose from. Whatever your budget, there's a package to suit you.

Where should I stay in Ladys Island?

We recommend staying near the action. Many visitors favor hotels around top attractions, such as Bay Street, Henry C. Chambers Waterfront Park and University of South Carolina-Beaufort.

What are the top hotels in Ladys Island?

Beautiful Water Views, Huge Yard and Flamingo Cove - Beautiful Deep Water Views are two of the most sought-after properties in Ladys Island. Why not look up the rates and amenities at each and then make a decision?

How far in advance should I book my Ladys Island vacation?

It's hard to pick the ideal time for airfares, but we normally say the earlier, the better. Many international journeys on Expedia become available to compare up to 12 months in advance. If you can't book early, don't stress. Bargain prices appear from time to time just weeks before departure dates.

What does an Expedia Ladys Island travel package include?

Hotels, rental cars and flights — we've got them well covered. With Expedia, you can shape your Ladys Island travel package however you want. All you have to do is work out what you need. Once you've made your booking, you can add on fun things like activities and experiences. The more you bundle, the greater the savings!

What should I know before booking a Ladys Island travel package?

Find deals to suit your budget with an Expedia package. Airfares, hotels, rental cars — we've got all of them. You'll save big bucks just for combining your bookings. Whether you're taking off on a winter adventure or sipping cocktails on a beach, your perfect getaway is only clicks away.

Can I choose my airline with a Ladys Island Expedia vacation package?

Expedia offers access to more than 550 partner airlines worldwide, so you certainly can. Just select the carrier you want and put together your ideal Ladys Island vacation.

If I'm not able to travel, can I cancel my Ladys Island vacation package?

If your travel plans in Ladys Island have been upended, it's a relief to know that it's possible to cancel your booking. If your booking was made within the last 24 hours, you may be eligible for a refund. If your booking was made more than 24 hours ago, your hotel, airline or car rental company may impose a cancellation fee. For more details, check our Customer Service Portal.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.