Knoxville Vacation Rentals

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Our top choices for Knoxville vacation rentals

4 King Suites w/ Hot Tub, Fire Pit, Ping Pong, Arcade, Hi Speed Internet

4 King Suites w/ Hot Tub, Fire Pit, Ping Pong, Arcade, Hi Speed Internet
Knoxville
10.0 out of 10, Exceptional, (23 reviews)
"Clean and open space for gathering "
United States
Jennifer K.
The price is CA $335
CA $831 total
includes taxes & fees
Apr 9 - Apr 10
4 King Suites w/ Hot Tub, Fire Pit, Ping Pong, Arcade, Hi Speed Internet

❤️ Secluded 1940s Romantic Tiny House on the River

❤️ Secluded 1940s Romantic Tiny House on the River
Shepherdstown
9.8 out of 10, Exceptional, (72 reviews)
"Cozy home, great location, and kind and helpful host. Would like to stay again. "
United States
Matthew S.
The price is CA $92
CA $186 total
includes taxes & fees
Apr 7 - Apr 8
❤️ Secluded 1940s Romantic Tiny House on the River

Birch Cabin at Hunting Creek Hideaway

Birch Cabin at Hunting Creek Hideaway
Thurmont
10.0 out of 10, Exceptional, (24 reviews)
"Beautiful location. Just what we were looking for."
United States
tony l.
The price is CA $127
CA $200 total
includes taxes & fees
Mar 31 - Apr 1
Birch Cabin at Hunting Creek Hideaway

Antietam Creek - Quiet 2 Bedroom Cabin

Antietam Creek - Quiet 2 Bedroom Cabin
Keedysville
9.2 out of 10, Wonderful, (89 reviews)
"This was an amazing cabin with a full kitchen so you could cook and enjoy the quiet."
United States
Lina A.
The price is CA $276
CA $461 total
includes taxes & fees
Mar 29 - Mar 30
Antietam Creek - Quiet 2 Bedroom Cabin

Pet-friendly, heart of downtown

Pet-friendly, heart of downtown
Frederick
10.0 out of 10, Exceptional, (8 reviews)
"This was a great property in an excellent location! Communication was great and the whole process was seamless. "
United States
nikki b.
The price is CA $83
CA $265 total
includes taxes & fees
Mar 31 - Apr 1
Pet-friendly, heart of downtown

Vintage cabin in the ❤️ of Middletown , MD. Pet friendly and prime location.

Vintage cabin in the ❤️ of Middletown , MD. Pet friendly and prime location.
Middletown
9.6 out of 10, Exceptional, (111 reviews)
"Cozy & dog friendly "
United States
Lauren F.
The price is CA $124
CA $290 total
includes taxes & fees
Apr 1 - Apr 2
Vintage cabin in the ❤️ of Middletown , MD. Pet friendly and prime location.

RETREAT on the CREEK - Businees Travelor or Weekend Getaway. HISTORIC DISTRICT.

RETREAT on the CREEK - Businees Travelor or Weekend Getaway. HISTORIC DISTRICT.
Downtown Frederick
9.4 out of 10, Exceptional, (124 reviews)
"The home was a great location to explore downtown Frederick. It had everything that we needed "
United States
David J.
The price is CA $154
CA $386 total
includes taxes & fees
Mar 30 - Mar 31
RETREAT on the CREEK - Businees Travelor or Weekend Getaway. HISTORIC DISTRICT.

Cozy, dog-friendly, downtown

Cozy, dog-friendly, downtown
Frederick
10.0 out of 10, Exceptional, (28 reviews)
"Clean, great location, friendly owner"
United States
Christian M.
The price is CA $82
CA $264 total
includes taxes & fees
Apr 1 - Apr 2
Cozy, dog-friendly, downtown

5-Minute Walk to Winery & Battlefield 1-Acre Wine Weekend Getaway w/ Fire Pit

5-Minute Walk to Winery & Battlefield 1-Acre Wine Weekend Getaway w/ Fire Pit
Sharpsburg
10.0 out of 10, Exceptional, (42 reviews)
"We had an amazing time - lots of walks and places to see - very historical - winery right next door which was an added bonus - accommodation was everything we needed and more - look out for a friendly cat that paid a few visits - thank you Jordan for a great time and will definitely come back to the area"
United Kingdom
Jo W.
The price is CA $145
CA $404 total
includes taxes & fees
Apr 1 - Apr 2
5-Minute Walk to Winery & Battlefield 1-Acre Wine Weekend Getaway w/ Fire Pit

Patty's Place - Private and Convenient EV-Friendly Apartment near Downtown

Patty's Place - Private and Convenient EV-Friendly Apartment near Downtown
Frederick
10.0 out of 10, Exceptional, (6 reviews)
"Amazing stay love this place very cozy house ."
United States
Aimee C.
The price is CA $84
CA $284 total
includes taxes & fees
Apr 1 - Apr 2
Patty's Place - Private and Convenient EV-Friendly Apartment near Downtown

Beautiful Remodeled Downtown Frederick Cottage (Pet-Friendly)

Beautiful Remodeled Downtown Frederick Cottage (Pet-Friendly)
Frederick
10.0 out of 10, Exceptional, (65 reviews)
"Great kitchen, very comfortable beds. Well air conditioned."
United States
Whitney C.
The price is CA $180
CA $384 total
includes taxes & fees
Apr 7 - Apr 8
Beautiful Remodeled Downtown Frederick Cottage (Pet-Friendly)

Leesburg Hideaway- King Bed + Private Backyard

Leesburg Hideaway- King Bed + Private Backyard
Leesburg
10.0 out of 10, Exceptional, (33 reviews)
"The host was great in communicating check in and check out instructions! We appreciated being able to park in the driveway and the fenced in back yard was also a nice amenity. Would definitely stay here again!"
United States
Katherine s.
The price is CA $186
CA $426 total
includes taxes & fees
Mar 29 - Mar 30
Leesburg Hideaway- King Bed + Private Backyard

Antietam Look Out - Incredible Sunset Views!

Antietam Look Out - Incredible Sunset Views!
Keedysville
9.8 out of 10, Exceptional, (36 reviews)
"Great communication, very clean, beautiful views!"
United States
Lorie K.
The price is CA $138
CA $493 total
includes taxes & fees
Apr 6 - Apr 7
Antietam Look Out - Incredible Sunset Views!

Bring Your Own Boat - Meticulously restored house on the Potomac River

Bring Your Own Boat - Meticulously restored house on the Potomac River
Hedgesville
10.0 out of 10, Exceptional, (9 reviews)
"Our stay was amazing and we really enjoyed ourselves. The place was perfect and quiet and peaceful! We will be booking with them again! "
United States
Kyndal B.
The price is CA $104
CA $223 total
includes taxes & fees
Mar 31 - Apr 1
Bring Your Own Boat - Meticulously restored house on the Potomac River

Loft Apt Just off C&O near Harpers Ferry and AT

Loft Apt Just off C&O near Harpers Ferry and AT
Brunswick
10.0 out of 10, Exceptional, (18 reviews)
"Our Hosts were wonderful and the space was great. It sits right off of the bike trail and across the street from a great bakery and bike shop. We thoroughly enjoyed our stay."
United States
Mark B.
The price is CA $149
CA $281 total
includes taxes & fees
Mar 29 - Mar 30
Loft Apt Just off C&O near Harpers Ferry and AT

Gorgeous apt, pets, hot tub & fire pit, walk --> DT Frederick

Gorgeous apt, pets, hot tub & fire pit, walk --> DT Frederick
Frederick
10.0 out of 10, Exceptional, (40 reviews)
"Everything was very clean and tidy, and very bright. The beds were extremely comfortable. Location was perfect and we really enjoyed having the backyard with a hot tub and a fire pit very relaxing."
United States
Donna C.
The price is CA $157
CA $372 total
includes taxes & fees
Mar 29 - Mar 30
Gorgeous apt, pets, hot tub & fire pit, walk --> DT Frederick

New townhouse

New townhouse
Frederick
9.4 out of 10, Exceptional, (9 reviews)
"This property was impeccably clean and so comfortable! The beds were incredibly cozy, and the kitchen was well-stocked. We felt right at home and enjoyed our stay immensely. Beds were comfortable, and kitchen well stocked. The location can't be beat, with so many attractions and wonderful restaurants within a short drive. Tons of nice touches for our arrival; great communication; easy access. We will definitely stay here again!"
United States
Traci U.
The price is CA $209
CA $503 total
includes taxes & fees
Mar 29 - Mar 30
New townhouse

Single Level, 3 Bedroom Home In Between Harper's Ferry & Casino.

Single Level, 3 Bedroom Home In Between Harper's Ferry & Casino.
Harpers Ferry
7.6 out of 10, Good, (27 reviews)
"The inside was well done and clean. Even though the neighbors are close, they were quiet. My husband and I were able to relax in a comfortable setting."
United States
Melissa H.
The price is CA $154
CA $370 total
includes taxes & fees
Mar 30 - Mar 31
Single Level, 3 Bedroom Home In Between Harper's Ferry & Casino.

Family & Pet Friendly Mountain Retreat~ Steam Shower~ 5 minutes from lake!

Family & Pet Friendly Mountain Retreat~ Steam Shower~ 5 minutes from lake!
Harpers Ferry
10.0 out of 10, Exceptional, (85 reviews)
"The host had great communication and the place was exactly as pictured! "
United States
Colleen J.
The price is CA $225
CA $496 total
includes taxes & fees
Mar 29 - Mar 30
Family & Pet Friendly Mountain Retreat~ Steam Shower~ 5 minutes from lake!

Sunny Streams Cabin - Sunset Views w/ a Hot Tub!

Sunny Streams Cabin - Sunset Views w/ a Hot Tub!
Keedysville
9.8 out of 10, Exceptional, (67 reviews)
"Great stay! We would book again. "
United States
Sam F.
The price is CA $138
CA $510 total
includes taxes & fees
Apr 13 - Apr 14
Sunny Streams Cabin - Sunset Views w/ a Hot Tub!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Knoxville Hotel Reviews

Find out more about Knoxville

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Knoxville. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Knoxville?

Yes, you can find vacation rentals near top local attractions in Knoxville, or you can go with a secluded option if you'd like a relaxing place to stay. Knoxville is known for its riverfront.

What are some of the best vacation home rentals that Knoxville has to offer?

Riverside cottage, minutes from historic Harpers Ferry! Private river access!: Visitors like this Knoxville vacation home rental. It offers a fireplace, a balcony, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You and your friends and family can relax into your vacation with amenities like a selection of games.

How many vacation rentals will I find in Knoxville?

With 9 Expedia vacation rentals, you're sure to find just the right place for your Knoxville stay.

What can I see and do in Knoxville?

Catoctin Valley and Chesapeake and Ohio Canal are a couple of lovely local spots to get outside and enjoy nature. While here, South Mountain State Park and Shenandoah River are other places worth a visit.

What are vacation rentals like in Knoxville?

Vacation rentals are private accommodations you can stay in for a few days or a quick weekend in Knoxville. Vacation rentals offer amenities such as patios, hot tubs, and fire pits so your stay will be comfortable. If you're concerned about a clean environment, a vacation rental can provide a sense of security away from public hotel elevators and busy concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great choice for family trips.