Title: Visit Sanctuary: Best of Sanctuary, Sanibel Travel 2026 | Expedia Tourism - Expedia.ca [Hotels in Sanctuary](https://expedia.ca/Sanctuary-Sanibel-Hotels.0-n553248635976469368-0.Travel-Guide-Filter-Hotels)[Flights to Sanibel](https://expedia.ca/Cheap-Flights-To-Sanibel.d9791.Travel-Guide-Flights)[Things to do in Sanibel](https://expedia.ca/Things-To-Do-In-Sanibel.d9791.Travel-Guide-Activities)[Sanctuary Car Rentals](https://expedia.ca/Car-Rentals-In-Sanctuary.d553248635976469368.Car-Rental-Guide)[Sanctuary Vacations](https://expedia.ca/Sanctuary.d553248635976469368.Destination-Travel-Guides) # Sanctuary ## Sanibel ## Visit Sanctuary Things to do Hotels Where to stay [Sanibel travel guide](https://expedia.ca/Sanibel.dx9791) --- ### Popular places to visit ![Seashells on Sanibel Island, Florida](https://images.trvl-media.com/place/553248635976194887/1681d0fb-bad0-43e3-9dad-05ad6264d3a8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Sanibel Island Southern Beach Why not spend a lazy afternoon at Sanibel Island Southern Beach during your trip to Sanibel? [](https://expedia.ca/Sanibel-Island-Southern-Beach-Fort-Myers.d553248635976194887.Vacation-Attraction) ![Sanibel Island Lighthouse which includes a beach, general coastal views and a sunset](https://images.trvl-media.com/place/6123905/4ca6a8bf-bcd7-4194-afd1-f40b40c7afaf.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Sanibel Island Lighthouse You can find out about the history of Sanibel when you stop by Sanibel Island Lighthouse. Wander the beautiful beaches and seaside in this family-friendly area. [](https://expedia.ca/Sanibel-Island-Lighthouse-Sanibel.d6123905.Vacation-Attraction) ![Bowman\'s Beach which includes general coastal views and a sandy beach](https://images.trvl-media.com/place/6296151/4495298b-a31a-40fc-a275-ded1cba6e62a.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Bowman's Beach Relax and revel in a visit to one of the area’s most beautiful beaches, great for swimming, fishing and finding special seashells. [](https://expedia.ca/Bowmans-Beach-West-End.d6296151.Vacation-Attraction) ![Periwinkle Way featuring a garden](https://images.trvl-media.com/place/6298863/ce898fdd-7ebf-4f44-9e80-60e95ba58831.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Periwinkle Way The island’s spine is also its commercial hub. Drive or bike the road’s length to find attractions and discover many stores and restaurants. [](https://expedia.ca/Periwinkle-Way-Sanibel.d6298863.Vacation-Attraction) ![J. N. Ding Darling National Wildlife Refuge showing a bridge as well as a small group of people](https://images.trvl-media.com/place/6123903/1af50fa6-38dc-4276-a6dd-5b04d07f72ce.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### J. N. Ding Darling National Wildlife Refuge See almost anything that flies, swims or crawls in Florida in this protected area. Become acquainted with wildlife while learning about varied species. [](https://expedia.ca/J-N-Ding-Darling-National-Wildlife-Refuge-Sanibel.d6123903.Vacation-Attraction) ![Fort Myers featuring a house](https://images.trvl-media.com/place/6296084/23eab012-1f55-4d52-8f9c-07eeb7f56326.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Sanibel Historical Museum and Village You can spend time browsing the exhibits at Sanibel Historical Museum and Village in Sanibel. Wander the beautiful beaches and seaside in this family-friendly area. [](https://expedia.ca/Sanibel-Historical-Museum-And-Village-Sanibel.d6296084.Vacation-Attraction) ### Things to do ![Ft Myers Beach Tiki Pub Fun in the Sun Dolphin Cruise](https://mediaim.expedia.com/localexpert/47153143/06bbabd1-82a1-4de2-bf45-a625ef00b5dc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Ft Myers Beach 2 Hour Tiki Pub Fun in the Sun Dolphin Cruise CA $61 per adult [](https://expedia.ca/things-to-do/ft-myers-beach-2-hour-tiki-pub-fun-in-the-sun-dolphin-cruise.a47153143.activity-details) ![Copacetic Day Sail](https://mediaim.expedia.com/localexpert/3146061/ce46a7d1-6271-4a2e-9229-41a28a522002.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Copacetic Day Sail CA $95 per adult **100%** of travellers recommend [](https://expedia.ca/things-to-do/copacetic-day-sail.a3146061.activity-details) ![Fort Myers Beach: Adults only BYOB Tiki Pub Daytime Cruise](https://mediaim.expedia.com/localexpert/47979072/6e9ee73a-5c48-4bd8-98b3-22dd86a327e5.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Fort Myers Beach: Tiki Pub Fun In The Sun Dolphin Cruise CA $89 per adult **100%** of travellers recommend [](https://expedia.ca/things-to-do/fort-myers-beach-tiki-pub-fun-in-the-sun-dolphin-cruise.a47979072.activity-details) ![Southwest Florida Sunset Sail](https://mediaim.expedia.com/localexpert/3146060/208129dd-2c36-4c94-bbae-6379e223335e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Southwest Florida Sunset Sail CA $95 per adult **100%** of travellers recommend [](https://expedia.ca/things-to-do/southwest-florida-sunset-sail.a3146060.activity-details) ![Dolphin Wildlife Cruise Fort Myers Beach](https://mediaim.expedia.com/localexpert/49515597/7ddf5e09-b4b4-4b06-b75b-dc221f49d5cd.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Dolphin Wildlife Cruise Fort Myers Beach CA $87 per adult [](https://expedia.ca/things-to-do/dolphin-wildlife-cruise-fort-myers-beach.a49515597.activity-details) ![Kayaking Rock Creek in the Bunche Beach Preserve](https://mediaim.expedia.com/localexpert/2599835/df2b31b4-45e3-4e6d-bcdf-fac67a52c2a6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Guided Kayak Eco Tour - Bunche Beach CA $95 per adult **98%** of travellers recommend [](https://expedia.ca/things-to-do/guided-kayak-eco-tour-bunche-beach.a2599835.activity-details) [See all activities in Sanibel](https://expedia.ca/Things-To-Do-In-Sanibel.d9791.Travel-Guide-Activities) --- ## Sanctuary Hotel Deals ![Margaritaville Beach Resort Fort Myers ](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/w3998h2821x0y0-a77e6574_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Margaritaville Beach Resort Fort Myers 251 Crescent Street Fort Myers Beach FL CA $383 CA $496 total Feb 16 - Feb 17 includes taxes & fees Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff ... 8.8/10 Excellent! (1,876 reviews) Very clean and beautiful pool! Reviewed on Feb 12, 2026 [](https://expedia.ca/Hotel-Search?startDate=16%2F02%2F2026&endDate=17%2F02%2F2026&selected=95126992&PinnedHotelID=95126992&HadPinnedHotel=true®ionId=553248635976469368) ![Sanibel Island Beach Resort](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sanibel Island Beach Resort 1231 Middle Gulf Dr Sanibel FL CA $581 CA $682 total Mar 4 - Mar 5 includes taxes & fees Book a stay at this beach hotel in Sanibel. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the restaurant in our reviews. ... 9/10 Wonderful! (1,591 reviews) Hotel was clean super cute and updated! Staff was excellent! We are definitely going to stay again! Reviewed on Feb 8, 2026 [](https://expedia.ca/Hotel-Search?startDate=04%2F03%2F2026&endDate=05%2F03%2F2026&selected=17298818&PinnedHotelID=17298818&HadPinnedHotel=true®ionId=553248635976469368) ![Lani Kai Beachfront Resort](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Lani Kai Beachfront Resort 1400 Estero Blvd Fort Myers Beach FL CA $466 CA $551 total Feb 16 - Feb 17 includes taxes & fees Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, an outdoor pool, and a beach locale. Popular attractions Key West Express and Crescent ... 8.8/10 Excellent! (1,217 reviews) They charge $20 to park at the hotel each day that was quite a rip off Reviewed on Feb 10, 2026 [](https://expedia.ca/Hotel-Search?startDate=16%2F02%2F2026&endDate=17%2F02%2F2026&selected=438796&PinnedHotelID=438796&HadPinnedHotel=true®ionId=553248635976469368) ![Hilton Garden Inn Ft Myers](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/d8bd559a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Garden Inn Ft Myers 12600 University Dr Fort Myers FL Fully refundableReserve now, pay when you stay CA $282 CA $315 total Mar 8 - Mar 9 includes taxes & fees Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ... 8.6/10 Excellent! (1,008 reviews) Nice quiet and clean. Reviewed on Feb 9, 2026 [](https://expedia.ca/Hotel-Search?startDate=08%2F03%2F2026&endDate=09%2F03%2F2026&selected=848740&PinnedHotelID=848740&HadPinnedHotel=true®ionId=553248635976469368) ![Marriott Sanibel Harbour Resort & Spa](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/ac9a3a07_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Marriott Sanibel Harbour Resort & Spa 17260 Harbour Pointe Dr Fort Myers FL CA $485 CA $588 total Feb 22 - Feb 23 includes taxes & fees Book a stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the helpful staff and the property ... 8.4/10 Very Good! (1,001 reviews) Nice room and perfect location Reviewed on Feb 1, 2026 [](https://expedia.ca/Hotel-Search?startDate=22%2F02%2F2026&endDate=23%2F02%2F2026&selected=3079&PinnedHotelID=3079&HadPinnedHotel=true®ionId=553248635976469368) ![Holiday Inn Express Cape Coral-Fort Myers Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Express Cape Coral-Fort Myers Area by IHG 1538 Cape Coral Pkwy E Cape Coral FL CA $231 CA $258 total Feb 22 - Feb 23 includes taxes & fees Book a stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ... 9.2/10 Wonderful! (1,215 reviews) Not my 1st time here, and everytime I leave with more reasons to come back. It was the 1st time with my children and they loved it as well. Reviewed on Feb 8, 2026 [](https://expedia.ca/Hotel-Search?startDate=22%2F02%2F2026&endDate=23%2F02%2F2026&selected=26860&PinnedHotelID=26860&HadPinnedHotel=true®ionId=553248635976469368) [See all 12,976 properties in Sanctuary](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=15%2F02%2F2026&endDate=16%2F02%2F2026®ionId=553248635976469368) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=DX-NH_SPRING_PROMO_553248635976469368) ## Check Sanctuary hotel availability [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976469368&startDate=2026-02-14&endDate=2026-02-15)[Feb 14 - Feb 15](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976469368&startDate=2026-02-14&endDate=2026-02-15) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976469368&startDate=2026-02-15&endDate=2026-02-16)[Feb 15 - Feb 16](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976469368&startDate=2026-02-15&endDate=2026-02-16) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976469368&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026)[Feb 20 - Feb 22](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976469368&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026) --- ### Other neighbourhoods around Sanctuary ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Del Sega If you're spending some time in Del Sega, Blind Pass Beach and J. N. Ding Darling National Wildlife Refuge are top sights worth seeing. [](https://expedia.ca/Sanibel-Del-Sega.dx553248635976469672) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Heron's Landing Though Heron's Landing might not have many top sights, you can venture to the surrounding area to see attractions like Bowman's Beach and Blind Pass Beach. [](https://expedia.ca/Sanibel-Herons-Landing.dx553248635976479011) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Tradewinds While Tradewinds might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Bowman's Beach and J. N. Ding Darling National Wildlife Refuge. [](https://expedia.ca/Sanibel-Tradewinds.dx553248635976472762) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Chateaux Sur Mer Though Chateaux Sur Mer might not have many top sights, you can venture to the surrounding area to see attractions like Bowman's Beach and J. N. Ding Darling National Wildlife Refuge. [](https://expedia.ca/Sanibel-Chateaux-Sur-Mer.dx553248635976472800) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### West End While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach. [](https://expedia.ca/Sanibel-West-End.dx977664051587067904) ![View of the Beach on the Gulf of Mexico at Sanibel Island Florida](https://images.trvl-media.com/place/553248635976479667/c29c42a5-d3e6-4e4c-a465-1be77fd7c74e.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Gulf Shores While there might not be top attractions in Gulf Shores, you can explore the larger area and discover places like Bowman's Beach and J. N. Ding Darling National Wildlife Refuge. [](https://expedia.ca/Sanibel-Gulf-Shores.dx553248635976479667) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Sanctuary ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app