Title: Top Hotels in Lafayette County | Expedia.ca [Vacation Rentals in Lafayette County](https://expedia.ca/Destinations-In-Lafayette-County.d553248635976430567.Vacation-Rental-Destinations)[Lafayette County Car Rentals](https://expedia.ca/Destinations-In-Lafayette-County.d553248635976430567.Car-Rental-Destinations)[Lafayette County Vacations](https://expedia.ca/Lafayette-County.d553248635976430567.Destination-Travel-Guides) ![kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida](https://images.trvl-media.com/place/553248635976197691/42181e6d-fd52-4c3e-bdcb-128d4daebc91.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248635976197691/42181e6d-fd52-4c3e-bdcb-128d4daebc91.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Lafayette County ![Branford Spring (A.K.A. Ivey Spring) in Ivey Memorial Park, Branford, Florida](https://images.trvl-media.com/place/6188028/c2e52b5f-3ee1-46e5-87da-f05b9ed110f8.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Branford [](https://expedia.ca/Branford-Hotels.d6188028.Travel-Guide-Hotels) ![The view of Manatee Springs and Suwannee River. Manatee Springs State Park is in Chiefland, Florida](https://images.trvl-media.com/place/6286979/5dd23773-1205-4776-836a-48316c56dcec.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Mayo [](https://expedia.ca/Mayo-Hotels.d6286979.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Apr 1 - Apr 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976430567&startDate=2026-04-01&endDate=2026-04-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 2 - Apr 3](https://www.expedia.ca/Hotel-Search?regionId=553248635976430567&startDate=2026-04-02&endDate=2026-04-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=553248635976430567&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=553248635976430567&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Lafayette County hotels ![3 outdoor pools, open 10:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/112000000/111770000/111760600/111760596/994169e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Cabin, Resort View | Terrace/patio](https://images.trvl-media.com/lodging/112000000/111770000/111760600/111760596/d134c1d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic House, 2 Bedrooms, Patio, River View | Terrace/patio](https://images.trvl-media.com/lodging/112000000/111770000/111760600/111760596/9fdd625a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Tent](https://images.trvl-media.com/lodging/112000000/111770000/111760600/111760596/ab1e5af8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Suwannee River Rendezvous [](https://www.expedia.ca/Mayo-Hotels-Suwannee-River-Rendezvous.h111760596.Hotel-Information) Mayo 8.8/10 Excellent (26 reviews) "We had a good family getaway and was impressed how the camping experience was . Me and my family had an awesome outdoor experience and we will return again . The people their welcomed you like family and mad the trip and safe " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) amy CA $38 CA $60 total includes taxes & fees Apr 2 - Apr 3 [](https://www.expedia.ca/Mayo-Hotels-Suwannee-River-Rendezvous.h111760596.Hotel-Information) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/118000000/117030000/117028300/117028207/b939a190.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/118000000/117030000/117028300/117028207/e4cf1fa4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117030000/117028300/117028207/5e6f1e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/118000000/117030000/117028300/117028207/2cb8b175.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi, [](https://www.expedia.ca/Mayo-Hotels-Friendlys-River-Retreat-1-Cozy-Couples-Cabin-In-Awesome-Mayo-With-WiFi.h117028207.Hotel-Information) Mayo 9.8/10 Exceptional (6 reviews) "Stacey is always very welcoming & I had everything I needed. It is very calm, serene and relaxing place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cathryn H. CA $61 CA $93 total includes taxes & fees Apr 2 - Apr 3 [](https://www.expedia.ca/Mayo-Hotels-Friendlys-River-Retreat-1-Cozy-Couples-Cabin-In-Awesome-Mayo-With-WiFi.h117028207.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/40000000/39450000/39448900/39448879/b31dcd5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/40000000/39450000/39448900/39448879/f9b4a9c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Camper with Kitchenette & Queen Size Bed | Private kitchen](https://images.trvl-media.com/lodging/40000000/39450000/39448900/39448879/2bf153e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room](https://images.trvl-media.com/lodging/40000000/39450000/39448900/39448879/ef8fed3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cindys Motel [](https://www.expedia.ca/Lake-City-Hotels-Cindys-Motel.h39448879.Hotel-Information) Mayo 8.8/10 Excellent (130 reviews) "Easy parking. Friendly staff. We extended our stay and had to switch rooms. The 1st kingsize bad was great. But when we changed rooms the queen size bed sagged in the middle." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARGARET CA $110 CA $119 total includes taxes & fees Apr 13 - Apr 14 [](https://www.expedia.ca/Lake-City-Hotels-Cindys-Motel.h39448879.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/116000000/115960000/115956900/115956827/a05c6668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/116000000/115960000/115956900/115956827/e14b74c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/116000000/115960000/115956900/115956827/79ac086d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/116000000/115960000/115956900/115956827/83d88153.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping [](https://www.expedia.ca/Mayo-Hotels-Friendlys-River-Retreat-Private-Rustic-Camping-Cabin-Sleeps-4with-Tent-Camping.h115956827.Hotel-Information) Mayo 9.8/10 Exceptional (9 reviews) "Had a great weekend away- it was just what me and my girlfriend needed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike S. CA $61 CA $123 total includes taxes & fees Apr 2 - Apr 3 [](https://www.expedia.ca/Mayo-Hotels-Friendlys-River-Retreat-Private-Rustic-Camping-Cabin-Sleeps-4with-Tent-Camping.h115956827.Hotel-Information) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/118000000/117580000/117572000/117571993/52c6d6ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117580000/117572000/117571993/01a8abcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/118000000/117580000/117572000/117571993/df1f85cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/118000000/117580000/117572000/117571993/fa8b9af9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house [](https://www.expedia.ca/Mayo-Hotels-RV-With-1full-Bed-2twin-Beds-And-AC-WiFi-Smart-TV-Bathroom-Outdoor-Shower-House.h117571993.Hotel-Information) Mayo 10/10 Exceptional (5 reviews) "Love this little slice of heaven!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Crystal CA $77 CA $110 total includes taxes & fees Apr 4 - Apr 5 [](https://www.expedia.ca/Mayo-Hotels-RV-With-1full-Bed-2twin-Beds-And-AC-WiFi-Smart-TV-Bathroom-Outdoor-Shower-House.h117571993.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/121000000/120020000/120014600/120014529/0b6f4e99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/121000000/120020000/120014600/120014529/dc37370b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, video games, DVD player, foosball](https://images.trvl-media.com/lodging/121000000/120020000/120014600/120014529/4a6f116a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120020000/120014600/120014529/ab3712bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River [](https://www.expedia.ca/Branford-Hotels-Charming-2-Bedroom-Cabin-In-Branford-Near-Santa-Fe-River.h120014529.Hotel-Information) Branford 10/10 Exceptional (7 reviews) "This house was fabulously decorated for Christmas! All of the amenities were precise and then some! Great location close to the springs. A must stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alicia R. CA $167 CA $337 total includes taxes & fees Apr 7 - Apr 8 [](https://www.expedia.ca/Branford-Hotels-Charming-2-Bedroom-Cabin-In-Branford-Near-Santa-Fe-River.h120014529.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/118000000/117880000/117876100/117876031/a801a884.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/118000000/117880000/117876100/117876031/4a655544_edited_3cf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/118000000/117880000/117876100/117876031/4db4defe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/118000000/117880000/117876100/117876031/df22288f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Log Cabin Retreat on the Santa Fe River – Nature, Kayaking & Relaxation! [](https://www.expedia.ca/Branford-Hotels-Cozy-Log-Cabin-Retreat-On-The-Santa-Fe-River-Nature.h117876031.Hotel-Information) Branford 10/10 Exceptional (14 reviews) "Great area of Florida to visit." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) D C. [](https://www.expedia.ca/Branford-Hotels-Cozy-Log-Cabin-Retreat-On-The-Santa-Fe-River-Nature.h117876031.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/113000000/112710000/112700100/112700041/2cdd0ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112710000/112700100/112700041/447da24d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/113000000/112710000/112700100/112700041/ad7792d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/113000000/112710000/112700100/112700041/fb150b4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming cabin 25 with 1 bedroom and Wi-Fi, fitness room, Pool in fabulous Mayo [](https://www.expedia.ca/Mayo-Hotels-Charming-Cabin-25-With-1-Bedroom-And-Wi-Fi.h112700041.Hotel-Information) Mayo 6.0/10 (2 reviews) "Great experience! My group had the best time here, the cabin was everything we expected and more" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Oriana S. [](https://www.expedia.ca/Mayo-Hotels-Charming-Cabin-25-With-1-Bedroom-And-Wi-Fi.h112700041.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/36000000/35540000/35530500/35530445/40faca7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/36000000/35540000/35530500/35530445/f5ddf271.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/36000000/35540000/35530500/35530445/08c45a00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/36000000/35540000/35530500/35530445/1deb5c26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY [](https://www.expedia.ca/O-Brien-Hotels-Margaritaville-BY-THE-Suwannee-River-Royal-Springs-PET-Friendly.h35530445.Hotel-Information) O'Brien 9.4/10 Exceptional (59 reviews) "A great get away for Labor Day weekend to do a little jet skiing with friends on the river and visiting all the local springs!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather H. CA $247 CA $564 total includes taxes & fees Apr 2 - Apr 3 [](https://www.expedia.ca/O-Brien-Hotels-Margaritaville-BY-THE-Suwannee-River-Royal-Springs-PET-Friendly.h35530445.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/113000000/112700000/112699800/112699770/304718a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112700000/112699800/112699770/7ea8f85c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/113000000/112700000/112699800/112699770/b0639512.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/113000000/112700000/112699800/112699770/ff939f33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy cabin 23 with Wi-Fi, AC, fitness room in charming Mayo [](https://www.expedia.ca/Mayo-Hotels-Cozy-Cabin-23-With-Wi-Fi.h112699770.Hotel-Information) Mayo 5.0/10 (2 reviews) "Property is amazing , but we rented a cabin that includes, stove and fridge and things needed to cook for a family ,we planned on cooking for sons birthday and a family of 6 when we got there they said they were overbooked and had to move us to a suit wich did not have things to cook so we had to go buy everything spending way more then excpected. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aj B. [](https://www.expedia.ca/Mayo-Hotels-Cozy-Cabin-23-With-Wi-Fi.h112699770.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/113000000/112710000/112700600/112700599/17a88122.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/113000000/112710000/112700600/112700599/0552a8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112710000/112700600/112700599/d05a94d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112710000/112700600/112700599/881b75fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming Hill Top Room 17 in Mayo with WiFi, AC, fitness room [](https://www.expedia.ca/Mayo-Hotels-Charming-Hill-Top-Room-17-In-Mayo-With-WiFi.h112700599.Hotel-Information) Mayo CA $139 CA $177 total includes taxes & fees Apr 2 - Apr 3 [](https://www.expedia.ca/Mayo-Hotels-Charming-Hill-Top-Room-17-In-Mayo-With-WiFi.h112700599.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/28000000/27590000/27580500/27580433/4e9f33b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/28000000/27590000/27580500/27580433/df532400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27590000/27580500/27580433/1cbcce69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/28000000/27590000/27580500/27580433/2efcbf96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ichetucknee Springs/Ginnie Springs/Santa Fe River at the Hideaway Cottage [](https://www.expedia.ca/Lake-City-Hotels-Ichetucknee-Springsginnie-Springs-On-The-Santa-Fe-River-At-The-Hideaway-Cottage.h27580433.Hotel-Information) Branford 10/10 Exceptional (123 reviews) "This was a great place to stay. It is secluded but near the Springs. The owners were pleasant. The owner even sent my daughter's ring back that they found after we left. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Constance A. [](https://www.expedia.ca/Lake-City-Hotels-Ichetucknee-Springsginnie-Springs-On-The-Santa-Fe-River-At-The-Hideaway-Cottage.h27580433.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/32000000/31100000/31097300/31097239/0e7fdf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books, stereo](https://images.trvl-media.com/lodging/32000000/31100000/31097300/31097239/76e358ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books, stereo](https://images.trvl-media.com/lodging/32000000/31100000/31097300/31097239/a2c75b03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/32000000/31100000/31097300/31097239/64f43a62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private 12 acre Ranch sleeps up to 8 on The Santa Fe River. [](https://www.expedia.ca/Lake-City-Hotels-Private-12-Acre-Ranch-Sleeps-Up-To-10-On-The-Santa-Fe-River.h31097239.Hotel-Information) high springs 9.8/10 Exceptional (85 reviews) "We had a great time and the hosts were so accommodating. Will definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carla W. [](https://www.expedia.ca/Lake-City-Hotels-Private-12-Acre-Ranch-Sleeps-Up-To-10-On-The-Santa-Fe-River.h31097239.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/112000000/111750000/111746300/111746216/abd63915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/112000000/111750000/111746300/111746216/e258a121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi](https://images.trvl-media.com/lodging/112000000/111750000/111746300/111746216/3aaba3cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111750000/111746300/111746216/f080c4db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Chalet On the Suwannee River [](https://www.expedia.ca/Mayo-Hotels-The-Chalet-On-The-Suwannee-River.h111746216.Hotel-Information) Mayo 10/10 Exceptional (1 review) "We were in the area to check out some local spring and loved the accessibility of this VRBO’s location. This property was amazing and super fun. Can’t wait to go back." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mandy B. CA $313 CA $378 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Mayo-Hotels-The-Chalet-On-The-Suwannee-River.h111746216.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/39000000/38540000/38534600/38534547/2af59b5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/39000000/38540000/38534600/38534547/c31a5b43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, DVD player, books](https://images.trvl-media.com/lodging/39000000/38540000/38534600/38534547/8a4a2129.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/39000000/38540000/38534600/38534547/034e5e10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Escape to Serenity at Suwannee River Rest – Pet-Friendly Lodge in North Florida [](https://www.expedia.ca/Branford-Hotels-Rest-Of-The-Suwannee-River.h38534547.Hotel-Information) Branford 10/10 Exceptional (68 reviews) "Host very helpful Very nice kitchen well stockedBeautiful river" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) joyce n. [](https://www.expedia.ca/Branford-Hotels-Rest-Of-The-Suwannee-River.h38534547.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/112000000/111720000/111715100/111715052/38d76379.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/112000000/111720000/111715100/111715052/bb56ff47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Soap, toilet paper](https://images.trvl-media.com/lodging/112000000/111720000/111715100/111715052/9978eab6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi](https://images.trvl-media.com/lodging/112000000/111720000/111715100/111715052/56e94fb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Treehouse on the Suwannee River [](https://www.expedia.ca/Mayo-Hotels-Treehouse-On-The-Suwannee-River.h111715052.Hotel-Information) Mayo 8.0/10 Very good (1 review) "Yeah, accommodations weren’t too bad. I mean for staying on the river and stuff that it wasn’t bad at all. The location was The only problem was is we were not informed that we had to bring our own bedsheets and pillows and cases and blankets and towels until the day of like the day we were getting ready to leave to head towards the VRBO that was a little much, especially when we were only staying for one night and it was very nice. I mean it’s very spacious. The furniture was a little outdated... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) samantha h. CA $327 CA $396 total includes taxes & fees Apr 2 - Apr 3 [](https://www.expedia.ca/Mayo-Hotels-Treehouse-On-The-Suwannee-River.h111715052.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/113000000/112710000/112700700/112700665/66b25564.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/113000000/112710000/112700700/112700665/87e071b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112710000/112700700/112700665/93e20e42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112710000/112700700/112700665/892e9d51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Hill Top Room 16 with WiFi, AC in tranquil Mayo [](https://www.expedia.ca/Mayo-Hotels-Cozy-Hill-Top-Room-16-With-WiFi.h112700665.Hotel-Information) Mayo CA $139 CA $177 total includes taxes & fees Apr 2 - Apr 3 [](https://www.expedia.ca/Mayo-Hotels-Cozy-Hill-Top-Room-16-With-WiFi.h112700665.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/91000000/90840000/90833100/90833008/df894617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90840000/90833100/90833008/66964a23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/91000000/90840000/90833100/90833008/a321f173_edited_f9aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/91000000/90840000/90833100/90833008/5ec6bd50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Butterfly Crossing peaceful getaway on the historic Suwannee. Fish, Boat, Relax [](https://www.expedia.ca/Branford-Hotels-Butterfly-Crossing-Peaceful-Getaway-On-The-Historic-Suwannee-Fish.h90833008.Hotel-Information) Branford 9.8/10 Exceptional (18 reviews) "The butterfly crossing was tries to its name. A peaceful getaway that my family needed. It was truly cozy, away from the city life and we enjoying doing campfires and taking the canoe out! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) J C. [](https://www.expedia.ca/Branford-Hotels-Butterfly-Crossing-Peaceful-Getaway-On-The-Historic-Suwannee-Fish.h90833008.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/112000000/111750000/111746100/111746080/f074de55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/112000000/111750000/111746100/111746080/326ae9b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Soap](https://images.trvl-media.com/lodging/112000000/111750000/111746100/111746080/c1a38396.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111750000/111746100/111746080/ba1ef966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHouse at Convict Springs [](https://www.expedia.ca/Mayo-Hotels-SpringHouse-At-Convict-Springs.h111746080.Hotel-Information) Mayo CA $153 CA $192 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Mayo-Hotels-SpringHouse-At-Convict-Springs.h111746080.Hotel-Information) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/109000000/108340000/108331900/108331858/b1809c66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/109000000/108340000/108331900/108331858/c5150eb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/109000000/108340000/108331900/108331858/152dbc3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/109000000/108340000/108331900/108331858/cd67c31e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Cottage at the Oasis near the Santa Fe River [](https://www.expedia.ca/Branford-Hotels-The-Cottage-At-The-Oasis-Near-The-Santa-Fe-River.h108331858.Hotel-Information) Branford 10/10 Exceptional (1 review) "Beautiful clean home in a beautiful area. Stayed here to go kayaking on the Ichtucknee and had a great time visiting the closest town, Fort White. Would definitely recommend this property!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alana S. [](https://www.expedia.ca/Branford-Hotels-The-Cottage-At-The-Oasis-Near-The-Santa-Fe-River.h108331858.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-15&endDate=2026-04-16®ionId=553248635976430567&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Great weekend hotel deals in Lafayette County, FL ### Showing deals for:**Apr 10 - Apr 12** ### Image gallery for Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi, ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/118000000/117030000/117028300/117028207/b939a190.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi, Mayo **9.8/10**Exceptional (6 reviews) 20% off CA $61 CA $159 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-04-10&endDate=2026-04-12&selected=117028207&adults=2) ### Image gallery for Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping ![Outdoor dining](https://images.trvl-media.com/lodging/116000000/115960000/115956900/115956827/a05c6668.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping Mayo **9.8/10**Exceptional (9 reviews) 20% off CA $67 CA $201 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-04-10&endDate=2026-04-12&selected=115956827&adults=2) ### Image gallery for The Best memories are made on the Suwannee River ![Property grounds](https://images.trvl-media.com/lodging/26000000/25140000/25134300/25134239/b4bbfe36.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### The Best memories are made on the Suwannee River Mayo **9.8/10**Exceptional (57 reviews) 10% off CA $170 CA $575 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-04-10&endDate=2026-04-12&selected=25134239&adults=2) ### Image gallery for Suwannee River Retreat with Private Dock, Free Kayaks, and Fire pit ![Exterior](https://images.trvl-media.com/lodging/61000000/60340000/60338600/60338546/9fae31c0.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Suwannee River Retreat with Private Dock, Free Kayaks, and Fire pit Mayo **10/10**Exceptional (73 reviews) 10% off CA $213 CA $725 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-04-10&endDate=2026-04-12&selected=60338546&adults=2) ### Image gallery for Suwannee River Rendezvous ![3 outdoor pools, open 10:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/112000000/111770000/111760600/111760596/994169e1.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Suwannee River Rendezvous Mayo **8.8/10**Excellent (26 reviews) 10% off CA $38 CA $100 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-04-10&endDate=2026-04-12&selected=111760596&adults=2) ### Image gallery for Cindys Motel ![BBQ/picnic area](https://images.trvl-media.com/lodging/40000000/39450000/39448900/39448879/b31dcd5e.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Cindys Motel Mayo **8.8/10**Excellent (130 reviews) 19% off CA $127 CA $275 total includes taxes & fees [](https://www.expedia.ca/Hotel-Search?startDate=2026-04-10&endDate=2026-04-12&selected=39448879&adults=2) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Lafayette-County.d553248635976430567.Hotel-Destinations)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Lafayette-County.d553248635976430567.Hotel-Destinations) ## Top Lafayette County Hotel Reviews ![Holiday Inn Express Hotel & Suites PERRY by IHG](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654331/137a1e6f_y.jpg) ### Holiday Inn Express Hotel & Suites PERRY by IHG 6/10 Okay "Everything at this location was great except for the smell when we entered the room and the very loud jet sound of the AC " [](https://expedia.ca/Tallahassee-Hotels-Holiday-Inn-Express-Hotel-Suites-PERRY.h2654331.Hotel-Information) ![Quality Inn & Suites Live Oak I-10 Exit 283](https://images.trvl-media.com/lodging/1000000/10000/3900/3861/b3ea89b2_y.jpg) ### Quality Inn & Suites Live Oak I-10 Exit 283 6/10 Okay "The Live Oak location is actually a little better than most" [](https://expedia.ca/Lake-City-Hotels-Quality-Inn-Suites.h3861.Hotel-Information) ![Days Inn by Wyndham Madison](https://images.trvl-media.com/lodging/1000000/30000/20400/20390/b4832d0c_y.jpg) ### Days Inn by Wyndham Madison 6/10 Okay "The room was nice and clean, the bed most comfortable, but no hot water in the morning for showers." [](https://expedia.ca/Tallahassee-Hotels-Days-Inn-By-Wyndham-Madison.h20390.Hotel-Information) ![Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy](https://images.trvl-media.com/lodging/111000000/110500000/110494400/110494372/5b1d647e_y.jpg) ### Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy 10/10 Excellent "all good" [](https://expedia.ca/High-Springs-Hotels-Postcard-Cabins-Gilchrist-Springs.h110494372.Hotel-Information) ![Super 8 by Wyndham Madison](https://images.trvl-media.com/lodging/1000000/870000/861700/861606/68cea7b0_y.jpg) ### Super 8 by Wyndham Madison 8/10 Good "It was what you expect for the price point and being the chain that it is. Staff were very nice. Room was clean. The room could use a good scrub on the baseboards and first impressions would go a long way if bayhroom water damage was fixed. Bathroom is incredibly tiny so to use it with the door shut it drove home the water damage behind the toilet, dirt in corners, and the shower curtain rod pulling from the wall. Coffee was available in the lobby in the morning, juice machine was broken, no food items. But gas stations and other quick eats nearby. It worked fine for our quick one night in late, out early just stop to sleep needs." [](https://expedia.ca/Tallahassee-Hotels-Super-8-By-Wyndham-Madison.h861606.Hotel-Information) ![Suwannee River Rendezvous](https://images.trvl-media.com/lodging/112000000/111770000/111760600/111760596/994169e1_y.jpg) ### Suwannee River Rendezvous 10/10 Excellent "We had a good family getaway and was impressed how the camping experience was . Me and my family had an awesome outdoor experience and we will return again . The people their welcomed you like family and mad the trip and safe " [](https://expedia.ca/Mayo-Hotels-Suwannee-River-Rendezvous.h111760596.Hotel-Information) ![Fiddler's Restaurant and Resort](https://images.trvl-media.com/lodging/89000000/88360000/88355400/88355341/50c270d8_y.jpg) ### Fiddler's Restaurant and Resort 6/10 Okay "?" [](https://expedia.ca/Steinhatchee-Hotels-Fiddlers-Restaurant-And-Resort.h88355341.Hotel-Information) ![Holiday Inn Express & Suites Live Oak by IHG](https://images.trvl-media.com/lodging/1000000/800000/798800/798756/ddd17ce3_y.jpg) ### Holiday Inn Express & Suites Live Oak by IHG 6/10 Okay "Breakfast and pool were fine. Shower in room 108 nedswork. " [](https://expedia.ca/Lake-City-Hotels-Holiday-Inn-Express-Hotel-Suites-LIVE-OAK.h798756.Hotel-Information) ![Steinhatchee River Inn](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880437/b7714606_y.jpg) ### Steinhatchee River Inn 8/10 Good "Spacious room" [](https://expedia.ca/Chiefland-Hotels-Steinhatchee-River-Inn.h4880437.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Lafayette County - [Mayo Hotels ](https://expedia.ca/Mayo-Hotels.d6286979.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Suwannee River ](https://expedia.ca/Suwannee-River-Hotels.0-l553248635976197691-0.Travel-Guide-Filter-Hotels) - [Hotels near Lafayette Blue Springs State Park ](https://expedia.ca/Lafayette-Blue-Springs-State-Park-Hotels.0-l553248621532654049-0.Travel-Guide-Filter-Hotels) - [Hotels near Troy Spring State Park ](https://expedia.ca/Troy-Spring-State-Park-Hotels.0-l6285999-0.Travel-Guide-Filter-Hotels) - [Hotels near Ginnie Spring ](https://expedia.ca/Ginnie-Spring-Hotels.0-l684510600363450368-0.Travel-Guide-Filter-Hotels) - [Hotels near Ichetucknee Springs State Park ](https://expedia.ca/Ichetucknee-Springs-State-Park-Hotels.0-l6285986-0.Travel-Guide-Filter-Hotels) - [Hotels near Madison Blue Springs State Park ](https://expedia.ca/Madison-Blue-Springs-State-Park-Hotels.0-l553248621561885532-0.Travel-Guide-Filter-Hotels) - [Hotels near Ruth B. Kirby Gilchrist Blue Springs State Park ](https://expedia.ca/Ruth-B-Kirby-Gilchrist-Blue-Springs-State-Park-Hotels.0-l553248621532654125-0.Travel-Guide-Filter-Hotels) - [Hotels near Suwannee River State Park ](https://expedia.ca/Suwannee-River-State-Park-Hotels.0-l6128386-0.Travel-Guide-Filter-Hotels) - [Hotels near Santa Fe River ](https://expedia.ca/Santa-Fe-River-Hotels.0-l684510373599707136-0.Travel-Guide-Filter-Hotels) - [Hotels near Sea Hag Marina ](https://expedia.ca/Sea-Hag-Marina-Hotels.0-l6184506-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Lafayette County - [Vacation Homes in Lafayette County ](https://expedia.ca/Lafayette-County-Private-Vacation-Homes.d553248635976430567-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Cottages in Lafayette County ](https://expedia.ca/Lafayette-County-Cottages.d553248635976430567-aaCottages.Travel-Guide-Accommodation) - [Cabin Rentals in Lafayette County ](https://expedia.ca/Lafayette-County-Cabins.d553248635976430567-aaCabins.Travel-Guide-Accommodation) - [Condo Rentals in Lafayette County ](https://expedia.ca/Lafayette-County-Condos.d553248635976430567-aaCondos.Travel-Guide-Accommodation) - [Resorts in Lafayette County ](https://expedia.ca/Lafayette-County-Resort-Hotels.d553248635976430567-aaResortHotels.Travel-Guide-Accommodation) - [Apartments in Lafayette County ](https://expedia.ca/Lafayette-County-Apartments.d553248635976430567-aaApartments.Travel-Guide-Accommodation) - [Motels in Lafayette County ](https://expedia.ca/Lafayette-County-Motels.d553248635976430567-aaMotels.Travel-Guide-Accommodation) - [RV Parks in Lafayette County ](https://expedia.ca/Lafayette-County-RV-Parks.d553248635976430567-aaRVParks.Travel-Guide-Accommodation) - [Villas in Lafayette County ](https://expedia.ca/Lafayette-County-Villas.d553248635976430567-aaVillas.Travel-Guide-Accommodation) - [Farmstay in Lafayette County ](https://expedia.ca/Lafayette-County-Agritourism.d553248635976430567-aaAgritourism.Travel-Guide-Accommodation) - [B&B in Lafayette County ](https://expedia.ca/Lafayette-County-Bed-And-Breakfast.d553248635976430567-aaBedAndBreakfast.Travel-Guide-Accommodation) ### Explore more hotels - [Suwannee River Rendezvous ](https://expedia.ca/Mayo-Hotels-Suwannee-River-Rendezvous.h111760596.Hotel-Information) - [Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi, ](https://expedia.ca/Mayo-Hotels-Friendlys-River-Retreat-1-Cozy-Couples-Cabin-In-Awesome-Mayo-With-WiFi.h117028207.Hotel-Information) - [Holiday Inn Express & Suites Live Oak by IHG ](https://expedia.ca/Lake-City-Hotels-Holiday-Inn-Express-Hotel-Suites-LIVE-OAK.h798756.Hotel-Information) - [Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy ](https://expedia.ca/High-Springs-Hotels-Postcard-Cabins-Gilchrist-Springs.h110494372.Hotel-Information) - [Good Times Motel and Marina ](https://expedia.ca/Steinhatchee-Hotels-Good-Times-Motel-And-Marina.h101945120.Hotel-Information) - [BlueGem Motel ](https://expedia.ca/High-Springs-Hotels-BlueGem-Motel.h87671816.Hotel-Information) - [Best Western Plus Madison ](https://expedia.ca/Tallahassee-Hotels-Best-Western-Plus-Madison-Inn.h59566.Hotel-Information) - [Holiday Inn Express Hotel & Suites PERRY by IHG ](https://expedia.ca/Tallahassee-Hotels-Holiday-Inn-Express-Hotel-Suites-PERRY.h2654331.Hotel-Information) - [Quality Inn & Suites Live Oak I-10 Exit 283 ](https://expedia.ca/Lake-City-Hotels-Quality-Inn-Suites.h3861.Hotel-Information) - [Days Inn by Wyndham Madison ](https://expedia.ca/Tallahassee-Hotels-Days-Inn-By-Wyndham-Madison.h20390.Hotel-Information) [See a list of all hotels in Lafayette County](https://expedia.ca/All-Lafayette-County-Hotels.d553248635976430567.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Lafayette County on Expedia.com ](https://www.expedia.com/Destinations-In-Lafayette-County.d553248635976430567.Hotel-Destinations) ### Expedia's Latest Trends Hotels - [Hotels in Collier County](https://expedia.ca/Destinations-In-Collier-County.d553248635976432392.Hotel-Destinations) - [Best Hotels in Kissimmee](https://expedia.ca/Kissimmee-Hotels.d7927.Travel-Guide-Hotels) - [Port of Miami hotels](https://expedia.ca/Port-Of-Miami-Hotels.0-l6125791-0.Travel-Guide-Filter-Hotels) - 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