
Antioquia Vacation Packages
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Your Antioquia Vacation
Leave all the planning up to us with an Antioquia vacation package. With everything arranged before you jet off, the only thing you'll need to do is relax and experience this destination's culture and charm. With so many things to explore on a trip to Antioquia, it can be tricky to know where to begin. Kick off your travels in Medellin at Santafé Mall and Lleras Park — two much-loved attractions here. Another city worth adding to your itinerary is Guatapé. Be sure not to miss Peñol-Guatapé Reservoir and Parque Comfama. From the instant you book your Antioquia vacation to when you return home, Expedia has your back each step of the way.
Top vacation destinations in Antioquia

Medellín
Top Antioquia Vacation Deals
Price found within the past 48 hours. Click for updated prices.

Blues Suites Medellin
El Poblado
Price was CA $1,907, price is now CA $1,371 per person
CA $1,371
per person
Jan 2 - Jan 8
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Medellín (MDE)
9/10 Wonderful! (1,337 reviews)
Great place, location, and warm, helpful staff!
Reviewed on Oct 26, 2026




Calle Flora Hotel by Jalo
El Poblado
Price was CA $2,069, price is now CA $1,451 per person
CA $1,451
per person
Jan 2 - Jan 8
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Medellín (MDE)
9/10 Wonderful! (1,540 reviews)
My stay at Calle Flora was great, but it was made even more amazing by a staff member by the name of Angelica. Angelica made sure to accommodate my request. She pointed out great restaurants and attractions in the area and region. She is bilingual, which was a huge plus for me given that I am English-speaking. When you visit, make sure to ask for Angelica!
Beyond the exceptional hospitality, the hotel itself is top-tier. Located right in the heart of El Poblado, the modern design, comfortable accommodations, and overall security made it the ideal base for my time in Medellín. The high-speed Wi-Fi and quiet atmosphere made working remotely seamless, while the surrounding neighborhood offered incredible dining and vibrant nightlife just steps away.
From seamless service to an unbeatable location, Calle Flora exceeded my expectations. I will definitely be staying here again on my next trip to Medellín!
Reviewed on Oct 27, 2026
Where to stay in Antioquia
Find the best Antioquia areas and neighborhoods for the activities you enjoy most.

El Poblado
Golden Blocks brimming with commercial activity, El Poblado offers vibrant nightlife at Lleras Park, cultural attractions like El Castillo Museum, and ample shopping options with multiple malls. Accessible via Medellín Metro and bus lines.

Laureles
Laureles is known for its ample dining options, and you can make a stop by Unicentro Shopping Center and Belén Andrés Escobar Sports Complex while in the area.

Provenza
If you're spending some time in Provenza, Galería Duque Arango and Lokkus Contemporary Art are top sights worth seeing.

Laureles - Estadio
While you're in Laureles - Estadio, take in top sights like Atanasio Giradot Stadium or Unicentro Shopping Center, and hop on the metro to see more the city at Estadio Station or Suramericana Station.

Zona Rosa
While Zona Rosa isn't home to many top sights, Golden Mile and Oviedo Shopping Center are some notable places to visit nearby.
Antioquia Hotel Deals

Hashtag 98 Hotel By Jalo
Carrera 41 # 10 - 37 Medellín Medellín
Fully refundableReserve now, pay when you stay
The price is CA $100 per night from Nov 2 to Nov 3
CA $100
CA $100 total
Nov 2 - Nov 3

Calle Flora Hotel by Jalo
# 37-40 Calle 9A Medellín
Fully refundableReserve now, pay when you stay
The price is CA $102 per night from Nov 10 to Nov 11
CA $102
CA $102 total
Nov 10 - Nov 11
9/10 Wonderful! (1,578 reviews)
"My stay at Calle Flora was great, but it was made even more amazing by a staff member by the name of Angelica. Angelica made sure to accommodate my request. She pointed out great restaurants and attractions in the area and region. She is bilingual, which was a huge plus for me given that I am English-speaking. ..."
Reviewed on Oct 27, 2026

Heiss Hotel By Jalo
1460 Cra. 43F Medellín Antioquia
Fully refundableReserve now, pay when you stay
The price is CA $88 per night from Nov 23 to Nov 24
CA $88
CA $88 total
Nov 23 - Nov 24
9.2/10 Wonderful! (2,043 reviews)
"Hotel esta muy limpio bonito y excelente staff muy atentos y seguro, tiene cerca muchos restaurantes en fin me volveria a quedar definitivamente"
Reviewed on Oct 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
What to do in Antioquia

PREMIUM Guatapé Tour: Rock, Luxury boat ride, Meals & Llamas
CA $62
per adult
98% of travellers recommend

Explore Guatapé and El Peñol from Medellín
CA $58
per adult
98% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
































