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Our top choices for South Central Houston hotels

1. The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum DistrictSouth Central Houston
9.2 out of 10, Wonderful, (1,285 reviews)
The price is CA $161
CA $200 total
includes taxes & fees
Nov 21 - Nov 22

2. Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical CenterSouth Central Houston
8.6 out of 10, Excellent, (2,254 reviews)
The price is CA $140
CA $165 total
includes taxes & fees
Nov 29 - Nov 30

3. Downtowner Inns - Houston Downtown
Downtowner Inns - Houston DowntownSouth Central Houston
9.2 out of 10, Wonderful, (280 reviews)
The price is CA $130
CA $152 total
includes taxes & fees
Nov 16 - Nov 17

4. InterContinental Houston by IHG
InterContinental Houston by IHGSouth Central Houston
9.4 out of 10, Exceptional, (1,008 reviews)
The price is CA $217
CA $282 total
includes taxes & fees
Nov 26 - Nov 27

5. DoubleTree by Hilton Houston Medical Center Hotel & Suites
DoubleTree by Hilton Houston Medical Center Hotel & SuitesSouth Central Houston
8.4 out of 10, Very good, (724 reviews)
The price is CA $163
CA $190 total
includes taxes & fees
Nov 24 - Nov 25

6. Houston Marriott Medical Center/Museum District
Houston Marriott Medical Center/Museum DistrictSouth Central Houston
9.0 out of 10, Wonderful, (1,000 reviews)
The price is CA $217
CA $300 total
includes taxes & fees
Nov 22 - Nov 23

7. Americas Best Value Inn Medical Center Downtown
Americas Best Value Inn Medical Center DowntownSouth Central Houston
8.0 out of 10, Very good, (1,001 reviews)
The price is CA $124
CA $145 total
includes taxes & fees
Nov 15 - Nov 16

8. 2824 Aeon Living
2824 Aeon LivingSouth Central Houston
The price is CA $212
CA $248 total
includes taxes & fees
Nov 22 - Nov 23

9. Hotel Zaza Houston Museum District
Hotel Zaza Houston Museum DistrictSouth Central Houston
9.2 out of 10, Wonderful, (1,017 reviews)
The price is CA $275
CA $390 total
includes taxes & fees
Nov 24 - Nov 25

10. La Maison in Midtown an urban B&B
La Maison in Midtown an urban B&BSouth Central Houston
9.8 out of 10, Exceptional, (612 reviews)
The price is CA $248
CA $290 total
includes taxes & fees
Dec 2 - Dec 3

11. Wanderstay Boutique Hotel
Wanderstay Boutique HotelSouth Central Houston
9.6 out of 10, Exceptional, (84 reviews)
The price is CA $187
CA $219 total
includes taxes & fees
Nov 16 - Nov 17

12. Hilton University of Houston
Hilton University of HoustonSouth Central Houston
9.0 out of 10, Wonderful, (1,001 reviews)
The price is CA $209
CA $245 total
includes taxes & fees
Nov 24 - Nov 25

13. Scott Inn Suites - Downtown Houston
Scott Inn Suites - Downtown HoustonSouth Central Houston
8.4 out of 10, Very good, (50 reviews)
The price is CA $90
CA $105 total
includes taxes & fees
Nov 18 - Nov 19

14. Sentral Forme Houston
Sentral Forme HoustonSouth Central Houston
9.2 out of 10, Wonderful, (102 reviews)
The price is CA $270
CA $357 total
includes taxes & fees
Dec 13 - Dec 14

15. Southmore Boulevard Motel
Southmore Boulevard MotelSouth Central Houston
5.8 out of 10, (245 reviews)
The price is CA $83
CA $98 total
includes taxes & fees
Nov 16 - Nov 17

16. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults OnlySouth Central Houston
9.6 out of 10, Exceptional, (222 reviews)
The price is CA $295
CA $367 total
includes taxes & fees
Nov 16 - Nov 17

17. Extended Stay America Suites Houston Med Ctr Braeswood Bl
Extended Stay America Suites Houston Med Ctr Braeswood BlSouth Central Houston
6.2 out of 10, (1,004 reviews)
The price is CA $96
CA $113 total
includes taxes & fees
Dec 13 - Dec 14

18. 2820 Blodgett St
2820 Blodgett StSouth Central Houston
The price is CA $387
CA $452 total
includes taxes & fees
Nov 18 - Nov 19

19. Historic Loft - 2 I NRG Medcenter Dtown Fifa
Historic Loft - 2 I NRG Medcenter Dtown FifaSouth Central Houston

20. Wanderstay Houston Hostel
Wanderstay Houston HostelSouth Central Houston
8.2 out of 10, Very good, (222 reviews)
The price is CA $69
CA $81 total
includes taxes & fees
Nov 16 - Nov 17
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare top hotels in South Central Houston
![]() The Westin Houston Medical Center/Museum DistrictSouth Central Houston | ![]() Hilton Houston Plaza/Medical CenterSouth Central Houston | ![]() Downtowner Inns - Houston DowntownSouth Central Houston | ![]() InterContinental Houston by IHGSouth Central Houston | ![]() DoubleTree by Hilton Houston Medical Center Hotel & SuitesSouth Central Houston |
|---|---|---|---|---|
9.2 Wonderful 1,285 reviews | 8.6 Excellent 2,254 reviews | 9.2 Wonderful 280 reviews | 9.4 Exceptional 1,008 reviews | 8.4 Very good 724 reviews |
The price is CA $161 CA $200 total includes taxes & fees Nov 21 - Nov 22 | The price is CA $140 CA $165 total includes taxes & fees Nov 29 - Nov 30 | The price is CA $130 CA $152 total includes taxes & fees Nov 16 - Nov 17 | The price is CA $217 CA $282 total includes taxes & fees Nov 26 - Nov 27 | The price is CA $163 CA $190 total includes taxes & fees Nov 24 - Nov 25 |
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Where to stay in South Central Houston
Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston

Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Texas Medical Center
Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.
Top South Central Houston Hotel Reviews

La Maison in Midtown an urban B&B
La Maison in Midtown an urban B&BSouth Central Houston











































































































