Santee Vacation Packages

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  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

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Santee Hotel Deals

Lewis and Clark Resort

Lewis and Clark Resort

2.5 out of 5
43496 Shore Drive Yankton SD
The price is CA $144 per night from Aug 10 to Aug 11
CA $144
CA $152 total
Aug 10 - Aug 11
includes taxes & fees
8.8/10 Excellent! (325 reviews)
"Fishing trip for three adult men. Good for what we was after. Good place for family stay. Only the one bathroom would be the only complaint if more people were along. Great view of lake."

Reviewed on Jul 8, 2026

Lewis and Clark Resort
Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

Crofton NE
The price is CA $883 per night from Jul 16 to Jul 17
CA $883
CA $1,647 total
Jul 16 - Jul 17
includes taxes & fees
10/10 Exceptional! (7 reviews)
"Lots of room! Friendly Host!"

Reviewed on Jul 7, 2026

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!
Fully furnished lake house with cozy spaces, full kitchen, and lake views.

Fully furnished lake house with cozy spaces, full kitchen, and lake views.

Crofton NE
10/10 Exceptional! (2 reviews)
"We enjoyed our stay."

Reviewed on Jun 28, 2026

Get rates
Fully furnished lake house with cozy spaces, full kitchen, and lake views.
See all 67 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does a Santee vacation package cost?
Offering excellent value package deals on Expedia, you'll be pleasantly surprised at how much a vacation to Santee costs! Expedia's packages make travel planning easier and your savings go further.
What are the cheapest months to go to Santee?
January, February and November are the best times to look for cheap Santee vacation packages. Travelling in less busy months means you'll typically find better prices on accommodations and flights.
How many days is enough for Santee?
With a well-planned schedule, you can easily visit the main Santee attractions in a handful of days. But if you want to explore off the beaten track or go on day trips, consider booking your Santee vacation for longer.
How to find the best Santee package deals?
Start your search for a Santee package deal by entering your preferred trip dates and destination under our "Packages" tab. Then apply a few filters, like "Property type" and "Amenities," to tailor the results to your exact style. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the ideal Santee package deal straight away, simply switch up your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Santee adventure underway.
Is it cheaper to book a Santee vacation as a package?
You can enjoy significant savings on your next Santee escape by booking a tailored vacation package. Check the "Package" heading, then select your travel dates and destination to view some great hotel prices and airfares. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Santee?
If you have your Santee travel dates finalized, book as soon as you can to score some fantastic deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spontaneous trips? Our last-minute deals are great for quick escapes.
How to plan a trip to Santee?

  1. Choose the ideal time to travel: Your schedule, favourite season and the type of weather you enjoy can all impact your decision on when to travel to Santee.
  2. Budget wisely: As well as the price of your stay, you should factor in other expenses. These include transportation, food and flights. Also, put aside a little extra for unexpected costs that may crop up during your trip to Santee.
  3. Decide how long to go for: Now that you're more familiar with Santee, you can work out the right length of your vacation. Create a draft itinerary and give yourself enough time to cover everything you want to see.
  4. Bundle your bookings: With your travel dates in order, you can combine your flights, car rental, hotels and more into a personalized Santee vacation package.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.