Title: Book The Best Hotels in Santa Isabel for 2025 from CA $50 - Competitive Prices - Expedia.ca

 

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# Find hotels in Santa Isabel from CA $50

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## Go beyond your typical stay in Santa Isabel

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Mexicali%2C+Baja+California%2C+Mexico&regionId=553248635975869828&latLong=32.632687%2C-115.577461&adults=2&startDate=2025-11-25&d1=2025-11-25&endDate=2025-11-27&d2=2025-11-27&travelerType=family_friendly)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Mexicali%2C+Baja+California%2C+Mexico&regionId=553248635975869828&latLong=32.632687%2C-115.577461&adults=2&startDate=2025-11-25&d1=2025-11-25&endDate=2025-11-27&d2=2025-11-27&amenities=POOL)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Mexicali%2C+Baja+California%2C+Mexico&regionId=553248635975869828&latLong=32.632687%2C-115.577461&adults=2&startDate=2025-11-25&d1=2025-11-25&endDate=2025-11-27&d2=2025-11-27&amenities=PETS)

## Check prices for these dates

Tonight

[Nov 11 - Nov 12](https://www.expedia.ca/Hotel-Search?regionId=553248635975869828&startDate=2025-11-11&endDate=2025-11-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Nov 12 - Nov 13](https://www.expedia.ca/Hotel-Search?regionId=553248635975869828&startDate=2025-11-12&endDate=2025-11-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635975869828&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248635975869828&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Compare 70 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/185f4103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 outdoor pools, open 10:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/883c858a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/a39bc3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/2d1b8a75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Araiza Mexicali

Mexicali

8.6/10

Excellent

(1669)

"Great hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Miguel

CA $125

CA $144 total

includes taxes & fees

Dec 2 - Dec 3

[](https://www.expedia.ca/Mexicali-Hotels-Hotel-Araiza-Mexicali.h22592.Hotel-Information)

![Daily cooked-to-order breakfast (MXN 290 per person)](https://images.trvl-media.com/lodging/1000000/610000/600500/600405/928ca1d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/610000/600500/600405/8e09f6a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/610000/600500/600405/b6948469.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite Ejecutiva King | Living area](https://images.trvl-media.com/lodging/1000000/610000/600500/600405/a09279f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Real Inn Mexicali

Civic Center

8.2/10

Very good

(1506)

"The staff was amazing, Rooms were super clean 5 star's..."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gilbert

CA $98

CA $111 total

includes taxes & fees

Dec 8 - Dec 9

[](https://www.expedia.ca/Mexicali-Hotels-Real-Inn-Mexicali.h600405.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/4d789164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/e8a107f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/50e75016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/70e7eb7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### One Mexicali

Mexicali

7.8/10

Good

(1000)

"Breakfast was delicious and it had several choices to pick."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Abraham

CA $94

CA $108 total

includes taxes & fees

Dec 6 - Dec 7

[](https://www.expedia.ca/Mexicali-Hotels-One-Mexicali.h17577142.Hotel-Information)

![Interior entrance](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/9bc6d08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/119b35fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/90810982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/677d7bf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sleep Inn Mexicali

Mexicali

8.2/10

Very good

(1009)

"Clean friendly staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jose

CA $94

CA $114 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Mexicali-Hotels-Sleep-Inn-Mexicali.h24081334.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/9be1b557.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/3c27d24e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/6e6f2982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 8:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/0cad0e57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### City Express Plus by Marriott Mexicali

Mexicali

8.6/10

Excellent

(947)

"Property was very clean and the staff was very nice! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Susana

CA $106

CA $119 total

includes taxes & fees

Dec 7 - Dec 8

[](https://www.expedia.ca/Mexicali-Hotels-City-Express-Plus-Mexicali.h44945342.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/fc9185d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/1b6e837a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/d5c9e706.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/b6aa67b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Mexicali by IHG

Mexicali

9.4/10

Exceptional

(1000)

"Staff members were awesome and the complementary breakfast was delicious."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Samuel

CA $156

CA $176 total

includes taxes & fees

Dec 7 - Dec 8

[](https://www.expedia.ca/Mexicali-Hotels-Holiday-Inn-Express-Suites-Mexicali.h12506422.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/19000000/18310000/18301100/18301092/e443b787.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Habitacion ejecutiva, dos camas](https://images.trvl-media.com/lodging/19000000/18310000/18301100/18301092/179fc335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Arcade](https://images.trvl-media.com/lodging/19000000/18310000/18301100/18301092/383d12a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/19000000/18310000/18301100/18301092/100934ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Siesta Real

Mexicali

8.2/10

Very good

(871)

"Everything went fine, the hotel is located in an area That is easy to walk to many good restaurants "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hugo

CA $104

CA $118 total

includes taxes & fees

Nov 13 - Nov 14

[](https://www.expedia.ca/Mexicali-Hotels-Hotel-Siesta-Real.h18301092.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/11000000/10080000/10071600/10071570/edfeecd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room | Bathroom](https://images.trvl-media.com/lodging/11000000/10080000/10071600/10071570/54625619.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Room](https://images.trvl-media.com/lodging/11000000/10080000/10071600/10071570/f5fe57d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily cooked-to-order breakfast](https://images.trvl-media.com/lodging/11000000/10080000/10071600/10071570/0e23dca5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Azteca de Oro Mexicali

Mexicali

7.6/10

Good

(424)

"Exelente"

![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg)

ALFREDO

CA $49

CA $55 total

includes taxes & fees

Nov 17 - Nov 18

[](https://www.expedia.ca/Mexicali-Hotels-Azteca-De-Oro-Mexicali.h10071570.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/8ef53b31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/d0790816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/5a6c7074.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bungalow, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/76d898ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Lucerna Mexicali

Mexicali

9.2/10

Wonderful

(1407)

"Very nice place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jorge

CA $150

CA $170 total

includes taxes & fees

Nov 24 - Nov 25

[](https://www.expedia.ca/Mexicali-Hotels-Hotel-Lucerna-Mexicali.h437408.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/a02730fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/28a69af3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, Multiple Beds](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/e6ace82e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/586cc6c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Mexicali

Mexicali

9.6/10

Exceptional

(1003)

"Great stay would go again"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hugo

CA $142

CA $160 total

includes taxes & fees

Nov 28 - Nov 29

[](https://www.expedia.ca/Mexicali-Hotels-Fairfield-Inn-Suites-By-Marriott-Mexicali.h33638137.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/18000000/17970000/17969200/17969178/5a8679ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed](https://images.trvl-media.com/lodging/18000000/17970000/17969200/17969178/fd4f05d0_edited_7172.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/18000000/17970000/17969200/17969178/8413905f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed | View from room](https://images.trvl-media.com/lodging/18000000/17970000/17969200/17969178/67882e84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Extended Suites Mexicali Cataviña

Mexicali

8.0/10

Very good

(2147)

"Excelent location and friendly staff!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jesus

[](https://www.expedia.ca/Mexicali-Hotels-Extended-Suites-Mexicali-Catavina.h17969178.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/2e8db822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/58d45afc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Double Room](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/f23e4d26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food and drink](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/da930419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Calafia Hotel

Eguía

8.2/10

Very good

(1003)

"Love this place."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eduardo

CA $105

CA $119 total

includes taxes & fees

Dec 7 - Dec 8

[](https://www.expedia.ca/Mexicali-Hotels-Calafia-Hotel.h22599.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/3b6504b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/218fae64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/a79edbbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/e439c29a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### City Express by Marriott Mexicali

Mexicali

8.2/10

Very good

(1001)

"Room spotless, staff Great."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Oscar

CA $114

CA $129 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Mexicali-Hotels-City-Express-Mexicali.h1661225.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/fbfdde79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/w4000h2662x0y0-04bf55ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/3b84677b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/1ad6da57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### City Express Junior by Marriott Mexicali

Mexicali

7.8/10

Good

(1002)

"Excellent location and great price. Will definitely stay here again"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Luis

CA $93

CA $105 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/Mexicali-Hotels-City-Express-Junior-Mexicali.h4610858.Hotel-Information)

![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/48bb48a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/3134e983.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/d9075b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room, 2 Double Beds](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/7d528f06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fiesta Inn Mexicali

Civic Center

8.2/10

Very good

(1000)

"The place is clean and close to main shoping center"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alejandro

CA $104

CA $118 total

includes taxes & fees

Dec 7 - Dec 8

[](https://www.expedia.ca/Mexicali-Hotels-Fiesta-Inn-Mexicali.h1152269.Hotel-Information)

![Deluxe Suite, Jetted Tub](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/c266de1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/0d3659aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Jetted Tub](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/0d0da065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/11d3da4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel Cies

Mexicali

9.2/10

Wonderful

(50)

"Excellent place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sandra

CA $71

CA $83 total

includes taxes & fees

Nov 13 - Nov 14

[](https://www.expedia.ca/Mexicali-Hotels-Motel-Cies.h102634000.Hotel-Information)

![Garden](https://images.trvl-media.com/lodging/1000000/920000/916300/916204/4796b47e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/920000/916300/916204/d898e4f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/920000/916300/916204/21f7b42d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/920000/916300/916204/f2c1f75c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Colonial Mexicali

Civic Center

8.0/10

Very good

(1006)

"Clean room, staff was great,working air conditioning."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Angelica

CA $136

CA $154 total

includes taxes & fees

Nov 14 - Nov 15

[](https://www.expedia.ca/Mexicali-Hotels-Hotel-Colonial-Mexicali.h916204.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/35c16f11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/c2ed0c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/c64aab50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/2ef4393d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Mexicali

Mexicali

9.4/10

Exceptional

(784)

"Great location, clean hotel rooms, friendly staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elizabeth

CA $146

CA $165 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Mexicali-Hotels-Courtyard-By-Marriott-Mexicali.h70919640.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/b9040e72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/92a837f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/a66b0fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Triple Room](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/0624ab03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Hacienda del Indio

Mexicali

7.2/10

Good

(130)

"It was a good stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveller

CA $45

CA $55 total

includes taxes & fees

Nov 13 - Nov 14

[](https://www.expedia.ca/Mexicali-Hotels-Hotel-Hacienda-Del-Indio.h18759903.Hotel-Information)

![Breakfast, lunch, dinner served; Mexican cuisine ](https://images.trvl-media.com/lodging/13000000/12630000/12628100/12628065/2bb3460a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Double Room](https://images.trvl-media.com/lodging/13000000/12630000/12628100/12628065/67a0ba31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/13000000/12630000/12628100/12628065/7954ee87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/13000000/12630000/12628100/12628065/4e6d9289.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Regis

Mexicali

7.2/10

Good

(114)

"Room was clean but too small it made me feel claustrophobic along with the parking lot"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karen

[](https://www.expedia.ca/Mexicali-Hotels-Hotel-Regis.h12628065.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-26&endDate=2025-11-27&regionId=553248635975869828&adults=2&sort=RECOMMENDED&openPlayBack=true)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Hotels.d553248635975869828.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Hotels.d553248635975869828.Travel-Guide-Hotels)

### Stay near popular Santa Isabel attractions

[](https://expedia.ca/Hospital-De-La-Familia-Hotels.0-l553248635977407856-0.Travel-Guide-Filter-Hotels)

#### Hospital de la Familia

Though Hospital de la Familia might be what brings you to town, perhaps you'll have a chance to explore more of Mexicali while you are here.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248635977407856)

[](https://expedia.ca/Hospital-Almater-SA-De-CV-Hotels.0-l553248635998002058-0.Travel-Guide-Filter-Hotels)

#### Hospital Almater SA de CV

Though Hospital Almater SA de CV might be what brings you to town, perhaps you'll have a chance to explore more of Mexicali while you are here.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248635998002058)

## More cheap stays in Santa Isabel

![Fairfield Inn & Suites by Marriott Mexicali](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/a02730fc_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Fairfield Inn & Suites by Marriott Mexicali

Calzada Manuel Gomez Morin 856, Colonia Rivera, Mexicali, BC

CA $142

CA $160 total

Nov 28 - Nov 29

includes taxes & fees

9.4/10 Exceptional! (1,001 reviews)

[](https://expedia.ca/Mexicali-Hotels-Fairfield-Inn-Suites-By-Marriott-Mexicali.h33638137.Hotel-Information)

![Motel Las Fuentes](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759923/794b14f4_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Motel Las Fuentes

Blvd Lopez Mateos 1655, Colonia Zacatecas, Mexicali, BC

CA $47

CA $58 total

Nov 13 - Nov 14

includes taxes & fees

7.8/10 Good! (146 reviews)

[](https://expedia.ca/Mexicali-Hotels-Motel-Las-Fuentes.h18759923.Hotel-Information)

![Motel Diana ](https://images.trvl-media.com/lodging/118000000/117770000/117766600/117766546/9ba5b8f3_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Motel Diana

200 Av. Tabasco Loma Linda, Mexicali, BC

CA $43

CA $50 total

Nov 13 - Nov 14

includes taxes & fees

9.6/10 Exceptional! (5 reviews)

[](https://expedia.ca/Mexicali-Hotels-Motel-Diana.h117766546.Hotel-Information)

![Hotel Misión Plaza Mexicali](https://images.trvl-media.com/lodging/102000000/101490000/101486400/101486351/17b18c98_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hotel Misión Plaza Mexicali

366 Av. Francisco I. Madero, Mexicali, BC

CA $51

CA $62 total

Nov 13 - Nov 14

includes taxes & fees

7.2/10 Good! (48 reviews)

[](https://expedia.ca/Tijuana-Hotels-Hotel-Mision-Plaza-Mexicali.h101486351.Hotel-Information)

![HOTEL DON QUIJOTE](https://images.trvl-media.com/lodging/112000000/111350000/111343500/111343437/6318d665_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### HOTEL DON QUIJOTE

Calz Independencia Independencia, 1782, Mexicali, BC

[Get rates](https://expedia.ca/Hotel-Search?startDate=26%2F11%2F2025&endDate=27%2F11%2F2025&selected=111343437&PinnedHotelID=111343437&HadPinnedHotel=true&regionId=553248635975869828)

6.8/10 (13 reviews)

[](https://expedia.ca/Mexicali-Hotels-HOTEL-DON-QUIJOTE.h111343437.Hotel-Information)

![Motel Olimpo](https://images.trvl-media.com/lodging/119000000/118100000/118098400/118098332/e16a19c6_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Motel Olimpo

KM 11.5 San Luis Río Colorado, Mexicali, BC

CA $50

CA $57 total

Nov 13 - Nov 14

includes taxes & fees

[](https://expedia.ca/Mexicali-Hotels-Motel-Olimpo.h118098332.Hotel-Information)

## Recent reviews of Santa Isabel hotels

![Real Inn Mexicali](//images.trvl-media.com/lodging/1000000/610000/600500/600405/928ca1d8_y.jpg)

### Real Inn Mexicali

5/5 Excellent

"I love it I will recommend to all my family and friends "

A verified traveller stayed at Real Inn Mexicali

Posted 3 days ago

[](https://expedia.ca/Mexicali-Hotels-Real-Inn-Mexicali.h600405.Hotel-Information)

![City Express by Marriott Mexicali](//images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/3b6504b5_y.jpg)

### City Express by Marriott Mexicali

5/5 Excellent

"Room spotless, staff Great."

A verified traveller stayed at City Express by Marriott Mexicali

Posted 4 days ago

[](https://expedia.ca/Mexicali-Hotels-City-Express-Mexicali.h1661225.Hotel-Information)

![Hotel del Norte](//images.trvl-media.com/lodging/9000000/8750000/8747200/8747120/744c9a61_y.jpg)

### Hotel del Norte

5/5 Excellent

"Room was very clean. Carpet is dated and worn. It is time to replace it. Staff is incredibly friendly and courteous. "

A verified traveller stayed at Hotel del Norte

Posted 5 days ago

[](https://expedia.ca/Mexicali-Hotels-Hotel-Del-Norte.h8747120.Hotel-Information)

![Hotel Lucerna Mexicali](//images.trvl-media.com/lodging/1000000/440000/437500/437408/8ef53b31_y.jpg)

### Hotel Lucerna Mexicali

5/5 Excellent

"Yes Staff is amazing Grounds are amazing and clean Definitely recommend the resort "

A verified traveller stayed at Hotel Lucerna Mexicali

Posted 5 days ago

[](https://expedia.ca/Mexicali-Hotels-Hotel-Lucerna-Mexicali.h437408.Hotel-Information)

![City Express Junior by Marriott Mexicali](//images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/fbfdde79_y.jpg)

### City Express Junior by Marriott Mexicali

5/5 Excellent

"Spotless room and very kind staff with nice breakfast. Secure parking"

A verified traveller stayed at City Express Junior by Marriott Mexicali

Posted 5 days ago

[](https://expedia.ca/Mexicali-Hotels-City-Express-Junior-Mexicali.h4610858.Hotel-Information)

![Sleep Inn Mexicali](//images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/9bc6d08f_y.jpg)

### Sleep Inn Mexicali

5/5 Excellent

"People are nice , not to clean , "

A verified traveller stayed at Sleep Inn Mexicali

Posted 5 days ago

[](https://expedia.ca/Mexicali-Hotels-Sleep-Inn-Mexicali.h24081334.Hotel-Information)

![Courtyard by Marriott Mexicali](//images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/35c16f11_y.jpg)

### Courtyard by Marriott Mexicali

5/5 Excellent

"Great location, clean hotel rooms, friendly staff. "

A verified traveller stayed at Courtyard by Marriott Mexicali

Posted 5 days ago

[](https://expedia.ca/Mexicali-Hotels-Courtyard-By-Marriott-Mexicali.h70919640.Hotel-Information)

![City Express Plus by Marriott Mexicali](//images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/9be1b557_y.jpg)

### City Express Plus by Marriott Mexicali

5/5 Excellent

"Excellent "

A verified traveller stayed at City Express Plus by Marriott Mexicali

Posted 6 days ago

[](https://expedia.ca/Mexicali-Hotels-City-Express-Plus-Mexicali.h44945342.Hotel-Information)

![Hotel Araiza Mexicali](//images.trvl-media.com/lodging/1000000/30000/22600/22592/185f4103_y.jpg)

### Hotel Araiza Mexicali

5/5 Excellent

"Excellent"

A verified traveller from Coquitlam stayed at Hotel Araiza Mexicali

Posted 7 days ago

[](https://expedia.ca/Mexicali-Hotels-Hotel-Araiza-Mexicali.h22592.Hotel-Information)

## Frequently asked questions

### Can I cancel my hotel reservation on Expedia?

> Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Santa Isabel hotel for you.

### How can I save on a Santa Isabel hotel booking with Expedia?

> Members always get our best prices. Find our best Santa Isabel hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.

### How much is the nightly rate at a Santa Isabel hotel?

> Prices for hotels in Santa Isabel often vary, but you can find a great deal from CA $50 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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