Title: Book The Best Hotels in Santa Isabel for 2026 from CA $57 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Santa Isabel](https://expedia.ca/Santa-Isabel-Vacation-Rentals.d553248635975869828.Travel-Guide-VacationRentals)[Santa Isabel Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Isabel.d553248635975869828.Car-Rental-Guide)[Santa Isabel Vacation Packages](https://expedia.ca/Santa-Isabel.d553248635975869828.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Isabel Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Mexicali%2C+Baja+California%2C+Mexico®ionId=553248635975869828&latLong=32.632687%2C-115.577461&adults=2&startDate=2026-03-02&d1=2026-03-02&endDate=2026-03-04&d2=2026-03-04&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Mexicali%2C+Baja+California%2C+Mexico®ionId=553248635975869828&latLong=32.632687%2C-115.577461&adults=2&startDate=2026-03-02&d1=2026-03-02&endDate=2026-03-04&d2=2026-03-04&amenities=POOL) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Mexicali%2C+Baja+California%2C+Mexico®ionId=553248635975869828&latLong=32.632687%2C-115.577461&adults=2&startDate=2026-03-02&d1=2026-03-02&endDate=2026-03-04&d2=2026-03-04&amenities=PETS) ## Check prices for these dates Tonight [Feb 16 - Feb 17](https://www.expedia.ca/Hotel-Search?regionId=553248635975869828&startDate=2026-02-16&endDate=2026-02-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 17 - Feb 18](https://www.expedia.ca/Hotel-Search?regionId=553248635975869828&startDate=2026-02-17&endDate=2026-02-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=553248635975869828&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=553248635975869828&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Isabel hotels ![Front of property](https://images.trvl-media.com/lodging/119000000/118100000/118098400/118098332/207aa423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/119000000/118100000/118098400/118098332/68ab4f9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/119000000/118100000/118098400/118098332/5f91ca4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room](https://images.trvl-media.com/lodging/119000000/118100000/118098400/118098332/5a5d49f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel Olimpo [](https://www.expedia.ca/Mexicali-Hotels-Motel-Olimpo.h118098332.Hotel-Information) Mexicali 7.2/10 Good (11 reviews) "Fit my expectations, great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yu CA $56 CA $64 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Mexicali-Hotels-Motel-Olimpo.h118098332.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/9000000/8750000/8747200/8747120/95c01e21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/9000000/8750000/8747200/8747120/eacc5dd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, Mexican cuisine](https://images.trvl-media.com/lodging/9000000/8750000/8747200/8747120/065d731c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Room, Non Smoking, City View](https://images.trvl-media.com/lodging/9000000/8750000/8747200/8747120/ad6c2bfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel del Norte [](https://www.expedia.ca/Mexicali-Hotels-Hotel-Del-Norte.h8747120.Hotel-Information) Mexicali Historic Center 8.2/10 Very good (1,004 reviews) "Manny is a great manager, the room was clean and the restaurant was good!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Crystal CA $73 CA $92 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/Mexicali-Hotels-Hotel-Del-Norte.h8747120.Hotel-Information) ![Double Room](https://images.trvl-media.com/lodging/118000000/117770000/117766600/117766546/9ba5b8f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/118000000/117770000/117766600/117766546/5f1e1f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/118000000/117770000/117766600/117766546/8ee9b5a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/118000000/117770000/117766600/117766546/0d752e56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel Diana [](https://www.expedia.ca/Mexicali-Hotels-Motel-Diana.h117766546.Hotel-Information) Mexicali 8.8/10 Excellent (9 reviews) "Very small room, location is good but everything in the area is narrow down including street width Ok for its value but i won't book here again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yu CA $49 CA $57 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Mexicali-Hotels-Motel-Diana.h117766546.Hotel-Information) ![Double Room, 1 Double Bed](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759923/2c4a970b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759923/20d370c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 1 Double Bed | Bathroom](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759923/ee17c01e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759923/9e8c57a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel Las Fuentes [](https://www.expedia.ca/Mexicali-Hotels-Motel-Las-Fuentes.h18759923.Hotel-Information) Mexicali 8.0/10 Very good (152 reviews) "Excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Cristofer CA $52 CA $63 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Mexicali-Hotels-Motel-Las-Fuentes.h18759923.Hotel-Information) ![Free self parking](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/1a5e5609.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/d431f14b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/68c76953.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/3af0c29f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hacienda del Indio [](https://www.expedia.ca/Mexicali-Hotels-Hotel-Hacienda-Del-Indio.h18759903.Hotel-Information) Mexicali 7.2/10 Good (137 reviews) "The room was clean and the parking was safe" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dulce CA $50 CA $61 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Mexicali-Hotels-Hotel-Hacienda-Del-Indio.h18759903.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/114000000/113170000/113166700/113166676/ecec9425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/114000000/113170000/113166700/113166676/w750h1125x0y104-f8100f1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/114000000/113170000/113166700/113166676/7ef26308.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/114000000/113170000/113166700/113166676/af19a542.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel Paraiso [](https://www.expedia.ca/Mexicali-Hotels-Motel-Paraiso.h113166676.Hotel-Information) Mexicali 9.0/10 Wonderful (2 reviews) "?" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) EMILIO CA $92 CA $114 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Mexicali-Hotels-Motel-Paraiso.h113166676.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/19000000/18310000/18300200/18300174/25e2656f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/19000000/18310000/18300200/18300174/88f0140c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18310000/18300200/18300174/94f4887b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Mexican cuisine ](https://images.trvl-media.com/lodging/19000000/18310000/18300200/18300174/3f92785c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Cosmos Don Carlos [](https://www.expedia.ca/Mexicali-Hotels-Hotel-Cosmos-Don-Carlos.h18300174.Hotel-Information) Mexicali 8.0/10 Very good (497 reviews) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gustavo Adolfo [](https://www.expedia.ca/Mexicali-Hotels-Hotel-Cosmos-Don-Carlos.h18300174.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/17000000/16500000/16490500/16490424/5c14c763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16500000/16490500/16490424/7ee22f2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16500000/16490500/16490424/0701066c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed](https://images.trvl-media.com/lodging/17000000/16500000/16490500/16490424/0e23354f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel Kiss [](https://www.expedia.ca/Mexicali-Hotels-Motel-Fronorte-Adults-Only.h16490424.Hotel-Information) Mexicali 7.8/10 Good (178 reviews) "Awesome Place highly recommend this place to everyone!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Manny [](https://www.expedia.ca/Mexicali-Hotels-Motel-Fronorte-Adults-Only.h16490424.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/35c16f11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Beds](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/e49e64aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/1f83fcf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/e9d53767.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Mexicali [](https://www.expedia.ca/Mexicali-Hotels-Courtyard-By-Marriott-Mexicali.h70919640.Hotel-Information) Mexicali 9.4/10 Exceptional (877 reviews) "The room was very clean,and the food was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cecilia CA $142 CA $160 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Mexicali-Hotels-Courtyard-By-Marriott-Mexicali.h70919640.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/70e7eb7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/87cba9ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/4a767773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/92dcdd98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### One Mexicali [](https://www.expedia.ca/Mexicali-Hotels-One-Mexicali.h17577142.Hotel-Information) Mexicali 7.8/10 Good (1,006 reviews) "Perfect location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Martin CA $90 CA $102 total includes taxes & fees Feb 19 - Feb 20 [](https://www.expedia.ca/Mexicali-Hotels-One-Mexicali.h17577142.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/d08d8cef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/w3995h2667x0y0-4074ca3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/62099386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/6d0d88b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express Plus by Marriott Mexicali [](https://www.expedia.ca/Mexicali-Hotels-City-Express-Plus-Mexicali.h44945342.Hotel-Information) Mexicali 8.6/10 Excellent (1,008 reviews) "Everything was good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose CA $117 CA $133 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Mexicali-Hotels-City-Express-Plus-Mexicali.h44945342.Hotel-Information) ![Deluxe Suite, Jetted Tub](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/6cf93e89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/11d3da4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Jetted Tub](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/0d0da065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/6dadaf5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel Cies [](https://www.expedia.ca/Mexicali-Hotels-Motel-Cies.h102634000.Hotel-Information) Mexicali 9.2/10 Wonderful (62 reviews) "Excellent place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra CA $92 CA $106 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Mexicali-Hotels-Motel-Cies.h102634000.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/fbfdde79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/df417812.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/3b84677b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/9d3ebf35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express Junior by Marriott Mexicali [](https://www.expedia.ca/Mexicali-Hotels-City-Express-Junior-Mexicali.h4610858.Hotel-Information) Mexicali 7.8/10 Good (1,003 reviews) "Room was very clean and the staff is very friendly!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Enrique CA $105 CA $118 total includes taxes & fees Feb 24 - Feb 25 [](https://www.expedia.ca/Mexicali-Hotels-City-Express-Junior-Mexicali.h4610858.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/a02730fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/586cc6c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/880c2ba5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/28a69af3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Mexicali [](https://www.expedia.ca/Mexicali-Hotels-Fairfield-Inn-Suites-By-Marriott-Mexicali.h33638137.Hotel-Information) Mexicali 9.6/10 Exceptional (1,008 reviews) "Excellent hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Orlando Alfonso CA $161 CA $182 total includes taxes & fees Mar 14 - Mar 15 [](https://www.expedia.ca/Mexicali-Hotels-Fairfield-Inn-Suites-By-Marriott-Mexicali.h33638137.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/8ab9b9fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Double Room](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/ecfa586d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/w2994h1998x6y0-159f4237.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/da930419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Calafia Hotel [](https://www.expedia.ca/Mexicali-Hotels-Calafia-Hotel.h22599.Hotel-Information) Mexicali 8.4/10 Very good (1,004 reviews) "Breakfast options are delicious, property location is centrally located, staff is friendly and responsive. The rooms are comfortable and a good size. Will be staying here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcela CA $118 CA $133 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Mexicali-Hotels-Calafia-Hotel.h22599.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/8ef53b31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bungalow, 1 King Bed](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/4fff491a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/4ee323df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/d0790816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Lucerna Mexicali [](https://www.expedia.ca/Mexicali-Hotels-Hotel-Lucerna-Mexicali.h437408.Hotel-Information) Mexicali 9.2/10 Wonderful (1,506 reviews) "Excellent location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey CA $145 CA $164 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Mexicali-Hotels-Hotel-Lucerna-Mexicali.h437408.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/a79edbbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/218fae64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/d67d6079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/1b3d0904.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express by Marriott Mexicali [](https://www.expedia.ca/Mexicali-Hotels-City-Express-Mexicali.h1661225.Hotel-Information) Mexicali 8.4/10 Very good (1,005 reviews) "Rooms were clean, staff was on point, thank you!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ernest CA $115 CA $130 total includes taxes & fees Feb 20 - Feb 21 [](https://www.expedia.ca/Mexicali-Hotels-City-Express-Mexicali.h1661225.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/c02f77f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/6bd2ca02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/3424fa53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/4380e4be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Araiza Mexicali [](https://www.expedia.ca/Mexicali-Hotels-Hotel-Araiza-Mexicali.h22592.Hotel-Information) Mexicali 8.6/10 Excellent (1,785 reviews) "Hotel staff was great, rooms were neat and clean, and the restaurant was delicious. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jorge CA $169 CA $191 total includes taxes & fees Feb 24 - Feb 25 [](https://www.expedia.ca/Mexicali-Hotels-Hotel-Araiza-Mexicali.h22592.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/107aba98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/7f649732.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/b6aa67b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed (Additional Living Area) | Living area](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/42c3081a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Mexicali by IHG [](https://www.expedia.ca/Mexicali-Hotels-Holiday-Inn-Express-Suites-Mexicali.h12506422.Hotel-Information) Mexicali 9.4/10 Exceptional (1,000 reviews) "Clean room, staff was polite and professional " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Irania CA $189 CA $214 total includes taxes & fees Feb 27 - Feb 28 [](https://www.expedia.ca/Mexicali-Hotels-Holiday-Inn-Express-Suites-Mexicali.h12506422.Hotel-Information) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/ab4e8dc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/90810982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/e0f97674.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/411fb8f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Mexicali [](https://www.expedia.ca/Mexicali-Hotels-Sleep-Inn-Mexicali.h24081334.Hotel-Information) Mexicali 8.2/10 Very good (1,004 reviews) "Clean beds, warm and good pressure water in the shower, free breakfast which was good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gema CA $101 CA $122 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Mexicali-Hotels-Sleep-Inn-Mexicali.h24081334.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-03&endDate=2026-03-04®ionId=553248635975869828&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=HTG_SPRING_PROMO_553248635975869828) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Hotels.d553248635975869828.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Hotels.d553248635975869828.Travel-Guide-Hotels) ## Top Santa Isabel Hotel Reviews ![Real Inn Mexicali](https://images.trvl-media.com/lodging/1000000/610000/600500/600405/928ca1d8_y.jpg) ### Real Inn Mexicali 10/10 Excellent "The staff was very helpful " [](https://expedia.ca/Mexicali-Hotels-Real-Inn-Mexicali.h600405.Hotel-Information) ![Courtyard by Marriott Mexicali](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/35c16f11_y.jpg) ### Courtyard by Marriott Mexicali 10/10 Excellent "Really enjoyed our stay , very clean , friendly staff , good parking. Really liked that there was a small shopping center next door and Starbucks! " [](https://expedia.ca/Mexicali-Hotels-Courtyard-By-Marriott-Mexicali.h70919640.Hotel-Information) ![Fairfield Inn & Suites by Marriott Mexicali](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/a02730fc_y.jpg) ### Fairfield Inn & Suites by Marriott Mexicali 10/10 Excellent "Good" [](https://expedia.ca/Mexicali-Hotels-Fairfield-Inn-Suites-By-Marriott-Mexicali.h33638137.Hotel-Information) ![Fiesta Inn Mexicali](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/48bb48a1_y.jpg) ### Fiesta Inn Mexicali 10/10 Excellent "Clean room" [](https://expedia.ca/Mexicali-Hotels-Fiesta-Inn-Mexicali.h1152269.Hotel-Information) ![Hotel Lucerna Mexicali](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/8ef53b31_y.jpg) ### Hotel Lucerna Mexicali 10/10 Excellent "Best lodging in the city. Excellent attentive staff." [](https://expedia.ca/Mexicali-Hotels-Hotel-Lucerna-Mexicali.h437408.Hotel-Information) ![Hotel Araiza Mexicali](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/185f4103_y.jpg) ### Hotel Araiza Mexicali 10/10 Excellent "Me gusto el hotel porque esta muy confortable y limpio. y la comida del restaurante muy buena." [](https://expedia.ca/Mexicali-Hotels-Hotel-Araiza-Mexicali.h22592.Hotel-Information) ![City Express Junior by Marriott Mexicali](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/fbfdde79_y.jpg) ### City Express Junior by Marriott Mexicali 10/10 Excellent "Room was very clean and the staff is very friendly!!!" [](https://expedia.ca/Mexicali-Hotels-City-Express-Junior-Mexicali.h4610858.Hotel-Information) ![Calafia Hotel](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/2e8db822_y.jpg) ### Calafia Hotel 10/10 Excellent "Yes." [](https://expedia.ca/Mexicali-Hotels-Calafia-Hotel.h22599.Hotel-Information) ![City Express by Marriott Mexicali](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/3b6504b5_y.jpg) ### City Express by Marriott Mexicali 10/10 Excellent "Fast check in and the staff is really attentive, clean room we had a good sleep after a tiring day " [](https://expedia.ca/Mexicali-Hotels-City-Express-Mexicali.h1661225.Hotel-Information) ## More cheap stays in Santa Isabel ![Motel Diana ](https://images.trvl-media.com/lodging/118000000/117770000/117766600/117766546/9ba5b8f3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel Diana 200 Av. Tabasco Loma Linda Mexicali BC CA $49 CA $57 total Mar 1 - Mar 2 includes taxes & fees 8.6/10 Excellent! (9 reviews) [](https://expedia.ca/Mexicali-Hotels-Motel-Diana.h117766546.Hotel-Information) ![Motel Las Fuentes](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759923/794b14f4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel Las Fuentes Blvd Lopez Mateos 1655 Mexicali BC CA $52 CA $63 total Feb 18 - Feb 19 includes taxes & fees 7.8/10 Good! (152 reviews) [](https://expedia.ca/Mexicali-Hotels-Motel-Las-Fuentes.h18759923.Hotel-Information) ![Motel Olimpo](https://images.trvl-media.com/lodging/119000000/118100000/118098400/118098332/e16a19c6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel Olimpo KM 11.5 San Luis Río Colorado Mexicali BC CA $56 CA $64 total Mar 1 - Mar 2 includes taxes & fees 7/10 Good! (11 reviews) [](https://expedia.ca/Mexicali-Hotels-Motel-Olimpo.h118098332.Hotel-Information) ![Fairfield Inn & Suites by Marriott Mexicali](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/a02730fc_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn & Suites by Marriott Mexicali Calzada Manuel Gomez Morin 856 Mexicali BC CA $161 CA $182 total Mar 14 - Mar 15 includes taxes & fees 9.4/10 Exceptional! (1,003 reviews) [](https://expedia.ca/Mexicali-Hotels-Fairfield-Inn-Suites-By-Marriott-Mexicali.h33638137.Hotel-Information) ![Hotel Misión Plaza Mexicali](https://images.trvl-media.com/lodging/102000000/101490000/101486400/101486351/17b18c98_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Misión Plaza Mexicali 366 Av. Francisco I. Madero Mexicali BC [Get rates](https://expedia.ca/Hotel-Search?startDate=03%2F03%2F2026&endDate=04%2F03%2F2026&selected=101486351&PinnedHotelID=101486351&HadPinnedHotel=true®ionId=553248635975869828) 7/10 Good! (53 reviews) [](https://expedia.ca/Tijuana-Hotels-Hotel-Mision-Plaza-Mexicali.h101486351.Hotel-Information) ![HOTEL DON QUIJOTE](https://images.trvl-media.com/lodging/112000000/111350000/111343500/111343437/6318d665_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOTEL DON QUIJOTE Calz Independencia Independencia Mexicali BC [Get rates](https://expedia.ca/Hotel-Search?startDate=03%2F03%2F2026&endDate=04%2F03%2F2026&selected=111343437&PinnedHotelID=111343437&HadPinnedHotel=true®ionId=553248635975869828) 6.8/10 (13 reviews) [](https://expedia.ca/Mexicali-Hotels-HOTEL-DON-QUIJOTE.h111343437.Hotel-Information) ## Frequently asked questions ### When is the best time to go to Santa Isabel? > These periods offer pleasant weather with comfortable temperatures, typically ranging from 20°C to 28°C, and less humidity compared to the summer. The skies are generally clear, making it ideal for enjoying the outdoor activities and natural beauty of the region. > > > For those looking to enjoy the coast, the spring and autumn months are superb for beach activities and exploring the Baja California coastline without the intense heat of summer or the cooler temperatures of winter. Couples seeking a relaxed getaway will find these seasons offer a peaceful experience, with fewer crowds than peak summer, allowing for more intimate experiences at local restaurants and attractions. > > > Solo travellers who appreciate exploring at their own pace will also find these times ideal. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa Isabel hotel booking with Expedia? ### How much is the nightly rate at a Santa Isabel hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Hotels near Adobe Guadalupe Vineyard ](https://www.expedia.ca/Adobe-Guadalupe-Vineyard-Hotels.0-l553248634214867984-0.Travel-Guide-Filter-Hotels) - [Civic Center Hotels ](https://www.expedia.ca/Civic-Center-Mexicali-Hotels.0-n6336107-0.Travel-Guide-Filter-Hotels) - [Mexicali Hotels ](https://www.expedia.ca/Destinations-In-Mexicali.d553248635640641487.Hotel-Destinations) - [Tecate Municipality Hotels ](https://www.expedia.ca/Destinations-In-Tecate-Municipality.d553248635975752024.Hotel-Destinations) - [Ejido Colima Hotels ](https://www.expedia.ca/Ejido-Colima-Hotels.d6294452.Travel-Guide-Hotels) - [Ejido Cucapah Mayor Hotels ](https://www.expedia.ca/Ejido-Cucapah-Mayor-Hotels.d553248635954882537.Travel-Guide-Hotels) - [Hotels near General Rodolfo Sanchez Taboada Intl. ](https://www.expedia.ca/General-Rodolfo-Sanchez-Taboada-Intl-Airport-Hotels.0-aMXL-0.Travel-Guide-Filter-Hotels) - [Guadalupe Victoria Hotels ](https://www.expedia.ca/Guadalupe-Victoria-Hotels.d620211026788466688.Travel-Guide-Hotels) - [Hotels near Hospital de la Familia ](https://www.expedia.ca/Hospital-De-La-Familia-Hotels.0-l553248635977407856-0.Travel-Guide-Filter-Hotels) - [La Rumorosa Hotels ](https://www.expedia.ca/La-Rumorosa-Hotels.d553248635823471502.Travel-Guide-Hotels) - [Cheap Hotels in Los Algodones ](https://www.expedia.ca/Los-Algodones-Hotels-Cheap-Hotels.0-0-d6158212-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Los Algodones ](https://www.expedia.ca/Los-Algodones-Hotels-Luxury-Hotel.0-0-d6158212-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Los Algodones ](https://www.expedia.ca/Los-Algodones-Hotels-Pet-Friendly-Hotel.0-0-d6158212-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Los Algodones ](https://www.expedia.ca/Los-Algodones-Hotels-Spa-Hotel.0-0-d6158212-tSpaHotel.Travel-Guide-Filter-Hotels) - [Los Algodones Hotels ](https://www.expedia.ca/Los-Algodones-Hotels.d6158212.Travel-Guide-Hotels) - [Luis Echeverria Alvarez Hotels ](https://www.expedia.ca/Luis-Echeverria-Alvarez-Hotels.d6347195.Travel-Guide-Hotels) - [Lgbt Friendly Hotels in Mediterráneo ](https://www.expedia.ca/Mediterraneo-Mexicali-Hotels-LGBT-Friendly-Hotel.0-n553248635921598967-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Accor Hotels in Mexicali ](https://www.expedia.ca/Mexicali-Hotels-Accor-Hotels.0-0-d2478--bAccorHotels.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Mexicali ](https://www.expedia.ca/Mexicali-Hotels-Cheap-Hotels.0-0-d2478-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Mexicali ](https://www.expedia.ca/Mexicali-Hotels-Hotels-With-Kitchenettes.0-0-d2478-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in Mexicali ](https://www.expedia.ca/Mexicali-Hotels-LGBT-Friendly-Hotel.0-0-d2478-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Mexicali ](https://www.expedia.ca/Mexicali-Hotels-Luxury-Hotel.0-0-d2478-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Mexicali ](https://www.expedia.ca/Mexicali-Hotels-Pet-Friendly-Hotel.0-0-d2478-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Mexicali ](https://www.expedia.ca/Mexicali-Hotels-Romantic-Hotel.0-0-d2478-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Mexicali ](https://www.expedia.ca/Mexicali-Hotels-Spa-Hotel.0-0-d2478-tSpaHotel.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Mexicali ](https://www.expedia.ca/Mexicali-Hotels-Wedding-Hotels.0-0-d2478-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Mexicali Hotels ](https://www.expedia.ca/Mexicali-Hotels.d2478.Travel-Guide-Hotels) - [Motels in Mexicali ](https://www.expedia.ca/Mexicali-Motels.d2478-aaMotels.Travel-Guide-Accommodation) - [Vacation Homes in Mexicali ](https://www.expedia.ca/Mexicali-Private-Vacation-Homes.d2478-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Morelos Hotels ](https://www.expedia.ca/Morelos-Hotels.d553248635822985053.Travel-Guide-Hotels) - [Nuevo Leon Hotels ](https://www.expedia.ca/Nuevo-Leon-Hotels.d6321455.Travel-Guide-Hotels) - [Spa Hotels in Santa Veronica ](https://www.expedia.ca/Santa-Veronica-Hotels-Spa-Hotel.0-0-d6347107-tSpaHotel.Travel-Guide-Filter-Hotels) - [Santa Veronica Hotels ](https://www.expedia.ca/Santa-Veronica-Hotels.d6347107.Travel-Guide-Hotels) - [Tecate Hotels ](https://www.expedia.ca/Tecate-Hotels.d179908.Travel-Guide-Hotels) - [Hotels near Trevista Vineyards ](https://www.expedia.ca/Trevista-Vineyards-Hotels.0-l553248621532630585-0.Travel-Guide-Filter-Hotels) - [Flights to Guadalupe Victoria ](https://www.expedia.ca/Cheap-Flights-To-Guadalupe-Victoria.d620211026788466688.Travel-Guide-Flights) - [Flights to Los Algodones ](https://www.expedia.ca/Cheap-Flights-To-Los-Algodones.d6158212.Travel-Guide-Flights) - [Flights to Mexicali ](https://www.expedia.ca/Cheap-Flights-To-Mexicali.d2478.Travel-Guide-Flights) - [Flights to Santa Veronica ](https://www.expedia.ca/Cheap-Flights-To-Santa-Veronica.d6347107.Travel-Guide-Flights) - [Flights from General Rodolfo Sanchez Taboada Intl. ](https://www.expedia.ca/lp/airports/mxl/flights-from-general-rodolfo-sanchez-taboada-intl-airport) - [Flights from Mexicali ](https://www.expedia.ca/lp/flights/2478/flights-from-mexicali) - [Flights from Los Algodones ](https://www.expedia.ca/lp/flights/6158212/flights-from-los-algodones) - [Flights from Addis Ababa (ADD) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/add/mxl/addis-ababa-to-mexicali) - [Flights from Bellingham (BLI) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/bli/mxl/bellingham-to-mexicali) - [Flights from Cancun (CUN) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/cun/mxl/cancun-to-mexicali) - [Flights from Calexico (CXL) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/cxl/mxl/calexico-to-mexicali) - [Flights from Guadalajara (GDL) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/gdl/mxl/guadalajara-to-mexicali) - [Flights from Hamburg (HAM) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/ham/mxl/hamburg-to-mexicali) - [Flights from El Centro (IPL) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/ipl/mxl/el-centro-to-mexicali) - [Flights from La Paz (LAP) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/lap/mxl/la-paz-to-mexicali) - [Flights from Las Vegas (LAS) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/las/mxl/las-vegas-to-mexicali) - [Flights from Los Angeles (LAX) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/lax/mxl/los-angeles-to-mexicali) - [Flights from Milan (LIN) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/lin/mxl/milan-to-mexicali) - [Flights from Mexico City (MEX) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/mex/mxl/mexico-city-to-mexicali) - [Flights from Monterrey (MTY) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/mty/mxl/monterrey-to-mexicali) - [Flights from Mazatlan (MZT) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/mzt/mxl/mazatlan-to-mexicali) - [Flights from Nairobi (NBO) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/nbo/mxl/nairobi-to-mexicali) - [Flights from Phoenix (PHX) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/phx/mxl/phoenix-to-mexicali) - [Flights from Pittsburgh (PIT) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/pit/mxl/pittsburgh-to-mexicali) - [Flights from Phnom Penh (PNH) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/pnh/mxl/phnom-penh-to-mexicali) - [Flights from Palm Springs (PSP) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/psp/mxl/palm-springs-to-mexicali) - [Flights from Panama City (PTY) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/pty/mxl/panama-city-to-mexicali) - [Flights from Puerto Vallarta (PVR) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/pvr/mxl/puerto-vallarta-to-mexicali) - [Flights from Puerto Escondido (PXM) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/pxm/mxl/puerto-escondido-to-mexicali) - [Flights from San Diego (SAN) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/san/mxl/san-diego-to-mexicali) - [Flights from Seattle (SEA) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/sea/mxl/seattle-to-mexicali) - [Flights from San José del Cabo (SJD) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/sjd/mxl/san-jose-del-cabo-to-mexicali) - [Flights from Santa Cruz (SRZ) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/srz/mxl/santa-cruz-to-mexicali) - [Flights from Edmonton (YEG) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/yeg/mxl/edmonton-to-mexicali) - [Flights from Halifax (YHZ) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/yhz/mxl/halifax-to-mexicali) - [Flights from Kelowna (YLW) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/ylw/mxl/kelowna-to-mexicali) - [Flights from Ottawa (YOW) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/yow/mxl/ottawa-to-mexicali) - [Flights from Regina (YQR) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/yqr/mxl/regina-to-mexicali) - [Flights from Montreal (YUL) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/yul/mxl/montreal-to-mexicali) - [Flights from Yuma (YUM) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/yum/mxl/yuma-to-mexicali) - [Flights from Vancouver (YVR) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/yvr/mxl/vancouver-to-mexicali) - [Flights from Winnipeg (YWG) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/ywg/mxl/winnipeg-to-mexicali) - [Flights from Saskatoon (YXE) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/yxe/mxl/saskatoon-to-mexicali) - [Flights from Calgary (YYC) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/yyc/mxl/calgary-to-mexicali) - [Flights from Victoria (YYJ) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/yyj/mxl/victoria-to-mexicali) - [Flights from Toronto (YYZ) to Mexicali (MXL) ](https://www.expedia.ca/lp/flights/yyz/mxl/toronto-to-mexicali) - [Hospital Almater SA de CV ](https://www.expedia.ca/Hospital-Almater-SA-De-CV-Mexicali.d553248635998002058.Vacation-Attraction) - [Juventud 2000 Sport Center ](https://www.expedia.ca/Juventud-2000-Sport-Center-Mexicali.d553248621551385142.Vacation-Attraction) - [La Rumorosa Vacations ](https://www.expedia.ca/La-Rumorosa.d553248635823471502.Destination-Travel-Guides) - [Visit La Rumorosa ](https://www.expedia.ca/La-Rumorosa.dx553248635823471502) - [Los Algodones Vacations ](https://www.expedia.ca/Los-Algodones.d6158212.Destination-Travel-Guides) - [Visit Los Algodones ](https://www.expedia.ca/Los-Algodones.dx6158212) - [Visit Civic Center ](https://www.expedia.ca/Mexicali-Civic-Center.dx6336107) - [Visit Zona Industrial ](https://www.expedia.ca/Mexicali-Zona-Industrial.dx553248635976399090) - [Mexicali Vacations ](https://www.expedia.ca/Mexicali.d2478.Destination-Travel-Guides) - [Visit Mexicali ](https://www.expedia.ca/Mexicali.dx2478) - [Santa Veronica Vacations ](https://www.expedia.ca/Santa-Veronica.d6347107.Destination-Travel-Guides) - [Car rental Los Algodones ](https://www.expedia.ca/Car-Rentals-In-Los-Algodones.d6158212.Car-Rental-Guide) - [Car rentals near Mexicali Border Port I ](https://www.expedia.ca/Car-Rentals-In-Mexicali-Border-Port-I.d553248635998150182.Car-Rental-Guide) - [Car rental Mexicali ](https://www.expedia.ca/Car-Rentals-In-Mexicali.d2478.Car-Rental-Guide) - [Pickup Car Rentals in Mexicali ](https://www.expedia.ca/Pickup-Car-Rentals-In-Mexicali.d2478-tPickup.Car-Rental-Guide-Class) - [Sixt Rental Cars in Mexicali ](https://www.expedia.ca/Sixt-Car-Rentals-In-Mexicali.d2478-c35.Car-Rental-Guide-Suppliers) - [Thrifty Car Rental Rental Cars in Los Algodones ](https://www.expedia.ca/Thrifty-Car-Rental-Car-Rentals-In-Los-Algodones.d6158212-c45.Car-Rental-Guide-Suppliers) - [Los Algodones Vacation Rentals ](https://www.expedia.ca/Los-Algodones-Vacation-Rentals.d6158212.Travel-Guide-VacationRentals) - [Mexicali Vacation Rentals ](https://www.expedia.ca/Mexicali-Vacation-Rentals.d2478.Travel-Guide-VacationRentals) - [Book Hotels in Santa Isabel on Expedia.mx ](https://www.expedia.mx/Santa-Isabel-Hoteles.d553248635975869828.Guia-Viajes-Hoteles) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app