Title: Visit Santa Cruz: Best of Santa Cruz Tourism | Expedia Travel Guide - Expedia.ca [Hotels in Santa Cruz](https://expedia.ca/Santa-Cruz-Hotels.d553248635973463921.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz](https://expedia.ca/Santa-Cruz-Vacation-Rentals.d553248635973463921.Travel-Guide-VacationRentals)[Santa Cruz Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Cruz.d553248635973463921.Car-Rental-Guide)[Santa Cruz Vacation Packages](https://expedia.ca/Santa-Cruz.d553248635973463921.Destination-Travel-Guides) # Santa Cruz ## Travel Guide ## Visit Santa Cruz - Santa Cruz Hotel Deals - Vacation Rentals in Santa Cruz ![Victoria Regia Hotel](https://images.trvl-media.com/lodging/2000000/1080000/1072100/1072075/5015dbeb_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Victoria Regia Hotel Ricardo Palma 252 Iquitos Loreto CA $114 CA $114 total Dec 17 - Dec 18 Book a stay at this business-friendly hotel in Iquitos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Tapiche Reserve and Plaza 28 de ... 8.4/10 Very Good! (253 reviews) Great, but the AC was a little noisy for my liking. Loved the breakfast. Reviewed on Nov 20, 2025 [](https://expedia.ca/Hotel-Search?startDate=17%2F12%2F2025&endDate=18%2F12%2F2025&selected=1072075&PinnedHotelID=1072075&HadPinnedHotel=true®ionId=553248635973463921) ![DoubleTree by Hilton Iquitos](https://images.trvl-media.com/lodging/4000000/3120000/3117500/3117426/01698dbb_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### DoubleTree by Hilton Iquitos Napo 258 Iquitos CA $167 CA $187 total Dec 24 - Dec 25 Book a stay at this luxury hotel in Iquitos. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our reviews. ... 8.6/10 Excellent! (358 reviews) Everything is excellent Reviewed on Dec 8, 2025 [](https://expedia.ca/Hotel-Search?startDate=24%2F12%2F2025&endDate=25%2F12%2F2025&selected=3117426&PinnedHotelID=3117426&HadPinnedHotel=true®ionId=553248635973463921) ![El Dorado Classic Hotel](https://images.trvl-media.com/lodging/4000000/3120000/3117500/3117457/106b105b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### El Dorado Classic Hotel Napo 362 Iquitos Loreto CA $67 CA $77 total Jan 3 - Jan 4, 2026 Stay at this hotel in Iquitos. Enjoy free breakfast, free WiFi, and room service. Popular attractions Plaza de Armas and The Iron House are located nearby. 8/10 Very Good! (122 reviews) This is a great stay that is in the center of Iquitos. I will gladly stay here the next time I travel back to the Jungle. Usually hotels in paces like Iquitos can be loud but this is a great hotel. Reviewed on Nov 2, 2025 [](https://expedia.ca/Hotel-Search?startDate=03%2F01%2F2026&endDate=04%2F01%2F2026&selected=3117457&PinnedHotelID=3117457&HadPinnedHotel=true®ionId=553248635973463921) [See all 211 properties in Loreto Region](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=17%2F12%2F2025&endDate=18%2F12%2F2025®ionId=6235145) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![City House](https://images.trvl-media.com/lodging/103000000/102680000/102670700/102670662/8bdf19b7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### City House Arica Iquitos Loreto Stay at this condo in Iquitos. Enjoy free WiFi, a rooftop terrace, and cable TV channels. Popular attractions Allpahuayo Mishana Bed & Trees and Amazon Golf ... [](https://expedia.ca/Iquitos-Hotels-City-House.h102670662.Hotel-Information) ![Apart hotel Emanuel & Cavita ](https://images.trvl-media.com/lodging/113000000/112880000/112876900/112876871/c442eb3b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Apart hotel Emanuel & Cavita 876 Av. Mariscal Caceres Iquitos Loreto Stay at this aparthotel in Iquitos. Enjoy free WiFi, a rooftop terrace, and daily housekeeping. Popular attractions Allpahuayo Mishana Bed & Trees and Plaza ... 10/10 Exceptional! (2 reviews) Itself a small apartment siited for purpose. Close to main square. Friendly accomodating team. If I'm back in Iquitos this will be my choice Reviewed on May 9, 2025 [](https://expedia.ca/Iquitos-Hotels-Apart-Hotel-Emanuel-Cavita.h112876871.Hotel-Information) ![La Quinta Loft Apartments](https://images.trvl-media.com/lodging/100000000/99250000/99245200/99245192/f8101ba9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Quinta Loft Apartments Huallaga Iquitos Loreto Stay at this aparthotel in Iquitos. Enjoy free WiFi, a 24-hour front desk, and concierge services. Popular attractions Tapiche Reserve and Plaza 28 de Julio ... 8/10 Very Good! (5 reviews) We had dead mosquitoes in the bed sheets. However, the receptionist was always friendly and helpful. Also, the water isn’t clean, it’s slightly brown. But this is because Iquitos is in the Amazon jungle. Reviewed on May 5, 2025 [](https://expedia.ca/Iquitos-Hotels-La-Quinta-Loft-Apartments.h99245192.Hotel-Information) [See all 211 properties in Loreto Region](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6235145&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santa Cruz hotel availability [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635973463921&startDate=2025-12-16&endDate=2025-12-17)[Dec 16 - Dec 17](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635973463921&startDate=2025-12-16&endDate=2025-12-17) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635973463921&startDate=2025-12-17&endDate=2025-12-18)[Dec 17 - Dec 18](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635973463921&startDate=2025-12-17&endDate=2025-12-18) [This weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635973463921&startDate=19%2F12%2F2025&endDate=21%2F12%2F2025)[Dec 19 - Dec 21](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635973463921&startDate=19%2F12%2F2025&endDate=21%2F12%2F2025) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635973463921&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025)[Dec 26 - Dec 28](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635973463921&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025) - Cities near Santa Cruz ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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