Santa Cruz Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Ready to book your vacation to Santa Cruz?
Santa Cruz Hotel Deals
Hotel de Turistas Iquitos
Napo Iquitos Loreto
Fully refundableReserve now, pay when you stay
CA $79
CA $79 total
Oct 17 - Oct 18
El Dorado Classic Hotel
Napo 362 Iquitos Loreto
Fully refundableReserve now, pay when you stay
CA $55
CA $69 total
Oct 14 - Oct 15
8.2/10 Very good! (157 reviews)
"friendly staff clean room and the hotel close to the center very accessible"
Reviewed on Oct 4, 2026
DoubleTree by Hilton Iquitos
Napo 258 Iquitos
Fully refundableReserve now, pay when you stay
CA $173
CA $193 total
Oct 19 - Oct 20
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Santa Cruz vacation package cost?
You'll find cheap prices on Expedia for your Santa Cruz getaway. However, a range of factors like the length of stay, the season and your choice of hotel will influence how much your vacation to Santa Cruz costs.
What are the cheapest months to go to Santa Cruz?
January, February and April are great times to look for cheap Santa Cruz vacation packages. Choosing to travel in quieter periods means you can generally find better prices on flights and accommodations.
How many days is enough for Santa Cruz?
The ideal duration of your Santa Cruz vacation depends on what you'd like to do and see. Generally, a handful of days to a week will give you plenty of time to hit all the main sights and discover some hidden spots along the way.
How to find the best Santa Cruz package deals?
Start your search for a Santa Cruz package deal by entering your destination and travel dates under our "Packages" tab. Then apply a few filters, like "Property type" and "Amenities," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with unbeatable savings. If you don't find the perfect Santa Cruz package deal right away, simply switch up your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Santa Cruz escape underway.
Is it cheaper to book a Santa Cruz vacation as a package?
An Expedia vacation package could land you considerable savings when compared to arranging accommodations and flights individually. Better still, you can tailor your Santa Cruz getaway to fit your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Check out our great deals to see how much you can save.
When to book a vacation package to Santa Cruz?
Secure fantastic discounts by booking your flights early with Expedia. If being spontaneous is more your style, snap up one of our last-minute deals for an impromptu Santa Cruz trip.
How to plan a trip to Santa Cruz?
- Pick the ideal time to travel: Your schedule, favourite season and the type of weather you like can all impact your decision on when to go to Santa Cruz.
- Set your budget: Consider expenses like flights, meals and transportation when calculating how much to put aside for your trip to Santa Cruz. Then, choose a hotel that fits your budget, whether that's a wallet-friendly stay or a more upscale retreat.
- Determine how many days away: Start by making a list of all the activities and attractions you'd like to experience in Santa Cruz. Then, estimate how long you'll need at each, along with any travel time.
- Bundle your bookings: With your travel dates in place, you can combine your car rental, flights, hotels and more into a personalized Santa Cruz vacation package.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
