Title: Book The Best Hotels in Santa Cruz for 2026 from CA $40 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Santa Cruz](https://expedia.ca/Santa-Cruz-Vacation-Rentals.d553248635973463921.Travel-Guide-VacationRentals)[Santa Cruz Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Cruz.d553248635973463921.Car-Rental-Guide)[Santa Cruz Vacation Packages](https://expedia.ca/Santa-Cruz.d553248635973463921.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 29 - Jan 30](https://www.expedia.ca/Hotel-Search?regionId=553248635973463921&startDate=2026-01-29&endDate=2026-01-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 30 - Jan 31](https://www.expedia.ca/Hotel-Search?regionId=553248635973463921&startDate=2026-01-30&endDate=2026-01-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248635973463921&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248635973463921&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Hotels.d553248635973463921.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Hotels.d553248635973463921.Travel-Guide-Hotels) ## Top Santa Cruz Hotel Reviews ## More cheap stays in Santa Cruz ![Alojamiento Casa Luna](https://images.trvl-media.com/lodging/118000000/117890000/117880200/117880171/21bff649_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Alojamiento Casa Luna 727 Jirón Rufino Echenique Iquitos Loreto CA $40 CA $40 total Jan 30 - Jan 31 [](https://expedia.ca/Iquitos-Hotels-Alojamiento-Casa-Luna.h117880171.Hotel-Information) ![Hotel Fenix](https://images.trvl-media.com/lodging/25000000/24240000/24237200/24237156/12990525_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Fenix Pasaje Angel Brusco 172-174 Iquitos Loreto CA $55 CA $55 total Jan 30 - Jan 31 9.8/10 Exceptional! (12 reviews) [](https://expedia.ca/Iquitos-Hotels-Hotel-Fenix.h24237156.Hotel-Information) ![Hotel La Casona](https://images.trvl-media.com/lodging/6000000/5320000/5318500/5318433/1d2d18a0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel La Casona Avenida Fitzcarrald 147 Iquitos Loreto CA $61 CA $61 total Jan 30 - Jan 31 8.4/10 Very Good! (129 reviews) [](https://expedia.ca/Iquitos-Hotels-Hotel-La-Casona.h5318433.Hotel-Information) ![Country Club Eco - Casa Jardín](https://images.trvl-media.com/lodging/35000000/34090000/34086300/34086221/f1671dd3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Country Club Eco - Casa Jardín Jr Manuel del Aguila 667 Moyobamba San Martin [Get rates](https://expedia.ca/Hotel-Search?startDate=12%2F02%2F2026&endDate=13%2F02%2F2026&selected=34086221&PinnedHotelID=34086221&HadPinnedHotel=true®ionId=553248635973463921) 8.2/10 Very Good! (10 reviews) [](https://expedia.ca/Tarapoto-Hotels-Country-Club-Eco-Casa-Jardin.h34086221.Hotel-Information) ![Studio 69](https://images.trvl-media.com/lodging/40000000/39020000/39016900/39016898/a84b49e8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Studio 69 Jr. Pevas 669 Iquitos Loreto [Get rates](https://expedia.ca/Hotel-Search?startDate=12%2F02%2F2026&endDate=13%2F02%2F2026&selected=39016898&PinnedHotelID=39016898&HadPinnedHotel=true®ionId=553248635973463921) 8.8/10 Excellent! (67 reviews) [](https://expedia.ca/Iquitos-Hotels-Studio-69.h39016898.Hotel-Information) ![ Hotel Laguna Azul](https://images.trvl-media.com/lodging/34000000/33620000/33617000/33616965/2634b5f2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Laguna Azul Jr.huallaga S/n Sauce San Martín [Get rates](https://expedia.ca/Hotel-Search?startDate=12%2F02%2F2026&endDate=13%2F02%2F2026&selected=33616965&PinnedHotelID=33616965&HadPinnedHotel=true®ionId=553248635973463921) 9/10 Wonderful! (15 reviews) [](https://expedia.ca/Tarapoto-Hotels-Laguna-Azul.h33616965.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Santa Cruz? > This central area is the heart of Santa Cruz, offering a convenient and accessible base for exploring. It's characterised by its historic architecture, pedestrian-friendly streets, and a pleasant overall feel. The Plaza de Armas itself is a focal point, surrounded by significant buildings like the Cathedral Basilica of Santa Cruz and the Casa de la Cultura. You'll find a concentration of shops, restaurants, and cafes within a few blocks of the plaza. > > > For couples, staying in this central district provides easy access to evening strolls, dining experiences, and cultural sites. Many hotels here offer a blend of traditional charm and modern comforts, making it simple to enjoy the city's offerings without extensive travel. The proximity to various eateries means a relaxed evening is always on the cards. > > > Solo travellers will also find the city centre an excellent option. Its central location means most attractions are within walking distance or a short taxi ride, and there's always something happening around the main square. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa Cruz hotel booking with Expedia? ### How much is the nightly rate at a Santa Cruz hotel? ## Explore a world of travel with Expedia - Lodging - [Jeberos Hotels ](https://www.expedia.ca/Jeberos-Hotels.d553248635973464457.Travel-Guide-Hotels) - [Lagunas Hotels ](https://www.expedia.ca/Lagunas-Hotels.d553248635973463236.Travel-Guide-Hotels) - [Teniente César López Rojas Hotels ](https://www.expedia.ca/Teniente-Cesar-Lopez-Rojas-Hotels.d553248635973462892.Travel-Guide-Hotels) - [Yurimaguas Hotels ](https://www.expedia.ca/Yurimaguas-Hotels.d4006.Travel-Guide-Hotels) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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