Zona Sur
Santa Cruz
Visit Zona Sur
Things to do
Santa Cruz and Porongo: History, Markets, River, and Culture
CA $138
per adult
4D/3N Expedition: Che Guevara Route - Disconnect from the World
CA $1,106
per adult
Samaipata Fort Tour: Ancient Ruins in 1 Full Day
CA $436
per adult
3D/2N Getaway on the Che Guevara Route Live the Adventure!
CA $968
per adult
Santa Cruz: 3-Day Expedition – Che Route, Trekking, and Wild Nature
CA $1,048
per adult
Santa Cruz: 2-day tour of the Che Guevara route in Bolivia
CA $967
per adult
Zona Sur Hotel Deals
Ibis Santa Cruz DE LA Sierra
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
The price is CA $60 per night from Sep 11 to Sep 12
CA $60
CA $60 total
Sep 11 - Sep 12
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (137 reviews)
"La ubicación es muy buena y puedes caminar por la zona"
Reviewed on Aug 31, 2026
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ave. San Martin, #455 Santa Cruz
The price is CA $199 per night from Sep 13 to Sep 14
CA $199
CA $199 total
Sep 13 - Sep 14
Book a stay at this spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (405 reviews)
"Breakfast is wonderful"
Reviewed on Sep 1, 2026
Marriott Santa Cruz de la Sierra Hotel
4to Anillo Entre Radial 23 Santa Cruz Santa Cruz
The price is CA $146 per night from Oct 2 to Oct 3
CA $146
CA $146 total
Oct 2 - Oct 3
Book a stay at this luxury hotel in Santa Cruz. Enjoy free parking, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (247 reviews)
"Staff was super as well as how clean the room was."
Reviewed on Aug 23, 2026
Camino Real Hotel
Av. San Martín y 4to. Anillo Santa Cruz
The price is CA $192 per night from Oct 7 to Oct 8
CA $192
CA $192 total
Oct 7 - Oct 8
Book a stay at this luxury hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and 2 bars/lounges. Popular attractions Ventura Mall and Centro Cultural ...
Sun Hotel
Av. Banzer Km 13 Santa Cruz Santa Cruz
The price is CA $151 per night from Oct 7 to Oct 8
CA $151
CA $151 total
Oct 7 - Oct 8
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Play Land Amusement Park is ...
8.2/10 Very good! (401 reviews)
"The staff was wonderful,airport shuttle was on time, the room was very clean!!"
Reviewed on Sep 5, 2026
Novotel Santa Cruz De La Sierra
AV ROCA CORONADO 901 Santa Cruz
The price is CA $171 per night from Oct 1 to Oct 2
CA $171
CA $171 total
Oct 1 - Oct 2
Book a stay at this luxury hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Ecológico and Patio Design LifeStyle ...
9/10 Wonderful! (129 reviews)
"All around good price and location"
Reviewed on Aug 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Zona Sur
Find the best Zona Sur areas and neighborhoods for the activities you enjoy most. Learn more about Zona Sur
Learn more about Zona Sur
Hamacas
While Hamacas isn't home to many top sights, Santa Cruz Zoo and Las Brisas Shopping Center are some notable places to visit nearby.
