A river with boats, a tower, and a sunset sky.

Hotels in Santa Clara, Seville

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Santa Clara hotels

1. Only YOU Hotel Sevilla

Only YOU Hotel Sevilla
5.0 star property
2.1 km from Santa Clara
9.8 out of 10, Exceptional, (995 reviews)
"Great breakfast, rooms and service"
United Kingdom
jonathan
The price is CA $219
CA $241 total
includes taxes & fees
Nov 30 - Dec 1
Only YOU Hotel Sevilla

2. Hotel Sevilla Center

Hotel Sevilla Center
4.0 star property
La Buhaira, 2.9 km from Santa Clara
9.2 out of 10, Wonderful, (1,292 reviews)
"Great place to stay"
United States
Dianela
The price is CA $105
CA $115 total
includes taxes & fees
Nov 30 - Dec 1
Hotel Sevilla Center

3. Eurostars Al-Ándalus Palace

Eurostars Al-Ándalus Palace
4.0 star property
5.1 km from Santa Clara
8.6 out of 10, Excellent, (1,296 reviews)
"Extremely pleased. Would come again!"
United States
manuel
The price is CA $112
CA $124 total
includes taxes & fees
Nov 8 - Nov 9
Eurostars Al-Ándalus Palace

4. Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center
4.0 star property
San Bartolomé, 3.2 km from Santa Clara
9.2 out of 10, Wonderful, (1,027 reviews)
"great location and everythikng else"
United States
reda
The price is CA $147
CA $162 total
includes taxes & fees
Dec 2 - Dec 3
Las Casas de la Judería, Sevilla Historic City Center

5. Adriano Hotel Boutique Sevilla

Adriano Hotel Boutique Sevilla
3.0 star property
El Arenal, 4.1 km from Santa Clara
9.4 out of 10, Exceptional, (1,647 reviews)
"Best place to stay!! Perfect location and the staff is amazing!!"
United States
Thomas
The price is CA $137
CA $151 total
includes taxes & fees
Nov 30 - Dec 1
Adriano Hotel Boutique Sevilla

6. Hotel Amadeus Sevilla

Hotel Amadeus Sevilla
4.0 star property
San Bartolomé, 3.3 km from Santa Clara
9.6 out of 10, Exceptional, (1,301 reviews)
"Beautiful hotel in great location."
United States
Kathie
The price is CA $183
CA $202 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Amadeus Sevilla

7. Hotel América Sevilla

Hotel América Sevilla
4.0 star property
Encarnación-Regina, 3.9 km from Santa Clara
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean comfortable room with excellent breakfast options."
United States
HANH
The price is CA $135
CA $149 total
includes taxes & fees
Nov 29 - Nov 30
Hotel América Sevilla

8. Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
5.0 star property
Santa Cruz, 3.9 km from Santa Clara
9.4 out of 10, Exceptional, (1,001 reviews)
"Beautiful hotel with classic features."
United States
Tomomi
The price is CA $676
CA $744 total
includes taxes & fees
Dec 2 - Dec 3
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

9. Hotel Giralda Center

Hotel Giralda Center
4.0 star property
San Bernardo, 3.2 km from Santa Clara
9.6 out of 10, Exceptional, (1,372 reviews)
"Nice hotel, close to tram snd Spanish Plaza. Lovely pool are"
Australia
Catherine
The price is CA $152
CA $167 total
includes taxes & fees
Dec 1 - Dec 2
Hotel Giralda Center

10. Hotel Murillo

Hotel Murillo
2.0 star property
Santa Cruz, 3.5 km from Santa Clara
9.0 out of 10, Wonderful, (1,109 reviews)
"Nice staff Very good breakfast Excellent location"
United States
Lucia
The price is CA $117
CA $129 total
includes taxes & fees
Nov 30 - Dec 1
Hotel Murillo

11. Becquer Hotel, Historic City Center

Becquer Hotel, Historic City Center
4.0 star property
Museo, 4.3 km from Santa Clara
9.8 out of 10, Exceptional, (1,017 reviews)
"Clean Great interaction with staff Polite and very helpful Great location Excellent breakfast Good quality WiFi"
Canada
Subash
The price is CA $161
CA $177 total
includes taxes & fees
Dec 2 - Dec 3
Becquer Hotel, Historic City Center

12. Hotel Gravina 51

Hotel Gravina 51
4.0 star property
Museo, 4.3 km from Santa Clara
9.8 out of 10, Exceptional, (1,003 reviews)
"Excellent beautiful hotel with great staff."
United States
Mandana
The price is CA $250
CA $275 total
includes taxes & fees
Dec 2 - Dec 3
Hotel Gravina 51

13. Hotel Fernando III

Hotel Fernando III
4.0 star property
San Bartolomé, 3.3 km from Santa Clara
9.6 out of 10, Exceptional, (1,385 reviews)
"Great location, friendly, relaxed and we would recommend this hotel for comfort and location."
United Kingdom
David
The price is CA $171
CA $188 total
includes taxes & fees
Dec 3 - Dec 4
Hotel Fernando III

14. Hesperia Sevilla

Hesperia Sevilla
4.0 star property
2.4 km from Santa Clara
9.4 out of 10, Exceptional, (759 reviews)
"Great location!"
United Kingdom
Mohammad
The price is CA $105
CA $115 total
includes taxes & fees
Nov 30 - Dec 1
Hesperia Sevilla

15. Melia Sevilla

Melia Sevilla
4.0 star property
3.3 km from Santa Clara
8.8 out of 10, Excellent, (1,000 reviews)
"Breakfast was amazing, friendly staff, great accommodations"
Canada
Dean
The price is CA $157
CA $173 total
includes taxes & fees
Nov 22 - Nov 23
Melia Sevilla

16. Ibis Styles Sevilla Santa Justa

Ibis Styles Sevilla Santa Justa
3.0 star property
2.5 km from Santa Clara
9.2 out of 10, Wonderful, (1,004 reviews)
"Good location, easy walking to famous places, helpful staff, clean room, excellent facilities, great food breakfast, recommend"
Canada
Judy
The price is CA $109
CA $120 total
includes taxes & fees
Nov 30 - Dec 1
Ibis Styles Sevilla Santa Justa

17. Hotel Rey Alfonso X

Hotel Rey Alfonso X
4.0 star property
San Bartolomé, 3.3 km from Santa Clara
9.4 out of 10, Exceptional, (1,214 reviews)
"Great location, walkable to all attractions, staff very receptive and helpful. Clean, functional rooms, breakfast with excellent selection. Very pleased, would stay again."
United States
Vitaliy
The price is CA $167
CA $183 total
includes taxes & fees
Dec 1 - Dec 2
Hotel Rey Alfonso X

18. Sercotel Sevilla Don Luciano

Sercotel Sevilla Don Luciano
3.5 star property
Historical Center, 3.9 km from Santa Clara
9.6 out of 10, Exceptional, (131 reviews)
"Beautiful hotel… great location … delicious breakfast"
Australia
Stacey
The price is CA $138
CA $152 total
includes taxes & fees
Nov 30 - Dec 1
Sercotel Sevilla Don Luciano

19. NH Collection Sevilla

NH Collection Sevilla
4.0 star property
3.1 km from Santa Clara
9.0 out of 10, Wonderful, (1,000 reviews)
"Great location, excellent breakfast buffet"
United States
Jose
The price is CA $121
CA $133 total
includes taxes & fees
Nov 30 - Dec 1
NH Collection Sevilla

20. Melia Lebreros

Melia Lebreros
4.0 star property
La Buhaira, 2 km from Santa Clara
9.0 out of 10, Wonderful, (1,001 reviews)
"Excellent hotel, everything was as good as I hoped for."
United Kingdom
John
The price is CA $131
CA $144 total
includes taxes & fees
Nov 30 - Dec 1
Melia Lebreros
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Clara

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A swimming pool with lounge chairs and umbrellas, surrounded by greenery and a wooden deck.
Catalonia Híspalis
3.0 star property
7.6
Good
369 reviews
View
A spacious lobby with a central seating area, large windows, and a high ceiling.
Only YOU Hotel Sevilla
5.0 star property
9.8
Exceptional
995 reviews
View
A spacious dining area with a large wooden table, wicker chairs, and pendant lighting.
Hesperia Sevilla
4.0 star property
9.4
Exceptional
759 reviews
View
A swimming pool with lounge chairs and umbrellas, surrounded by trees and buildings.
Melia Lebreros
4.0 star property
9.0
Wonderful
1,001 reviews
View
A modern indoor dining area with a pool view, clear glass chairs, and a bar with various bottles.
Hotel AACR Monteolivos
3.0 star property
8.6
Excellent
452 reviews
View

Where to stay in Santa Clara

Find the best Santa Clara areas and neighborhoods for the activities you enjoy most.

Historical Center

Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.

Santa Cruz

Explore Seville's historic heart with its labyrinth of narrow streets, plazas like Plaza de Santa Cruz, and iconic landmarks such as the Giralda. Enjoy walkability and shade during hot summers, while discovering bars and terraces at Plaza de los Venerables.

El Arenal

Located in Seville's historical center, El Arenal boasts the 13th-century Torre del Oro, Royal Shipyards, and La Real Maestranza bullring. Explore this vibrant area on the Guadalquivir river's east bank.

Alfalfa

Unique features of Alfalfa include the bars and historic sites. Make a stop by Calle Sierpes or Casa de la Memoria Cultural Center while you're exploring the area.

Triana

Discover traditional pottery and vibrant flamenco culture in this lively area. Shop at Triana Market for local crafts and tapas, or explore Calle Betis for popular restaurants, bars, and nightclubs.

Top Santa Clara Hotel Reviews

Frequently asked questions

What other neighbourhoods are similar to Santa Clara?
While Santa Clara is quite unique in its offering of a tranquil, residential feel within Seville, the closest neighbourhoods that share some similar characteristics are Los Remedios and Nervión.

Los Remedios, located south of the historic centre across the Guadalquivir River, offers a refined, residential experience without the constant bustle of the more tourist-heavy areas. It's known for its wide, tree-lined avenues, elegant apartment buildings, and a good selection of high-end shops and restaurants, particularly along Calle Asunción. It also has easy access to Parque de los Príncipes, a large urban park.

This neighbourhood is an excellent choice for couples looking for a relaxed yet sophisticated stay. You'll find a good balance of local life and convenience, with plenty of opportunities for leisurely strolls and enjoying high-quality dining without the crowds. It's also well-connected to the city centre by public transport.

Nervión, to the east of the historic centre, is another area that blends residential comfort with commercial amenities. It's a more modern district compared to Los Remedios, characterised by contemporary architecture, large department stores, and a wide array of eateries. The district is home to the Ramón Sánchez Pizjuán Stadium and the bustling shopping area around Avenida Luis de Morales.

For travellers who appreciate modern conveniences and a lively, local atmosphere, Nervión is a good option.
When is the best time to go to Santa Clara?
The best time to visit Santa Clara, Andalusia, is during the spring (April to June) and autumn (September to October) months.

During spring, the weather is pleasantly warm, typically ranging from 20°C to 28°C, making it ideal for exploring the city's outdoor attractions without the intense heat of summer. You'll find the parks and gardens, such as the Jardines de Murillo, in full bloom, offering a beautiful backdrop for strolls. This period is particularly good for couples looking for a romantic getaway, as the city is alive with a gentle energy and outdoor dining becomes very inviting.

Autumn offers similarly agreeable temperatures, usually between 20°C and 27°C, and the city is less crowded than in the peak summer months. This season is great for those who enjoy cultural exploration, as many local festivals and events take place. Families might find this a great time to visit, as the milder weather is comfortable for children to explore historical sites like the Royal Alcázar and enjoy the open-air markets without discomfort.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Santa Clara hotel for you.
How much is the nightly rate at a Santa Clara hotel?
Hotel prices in Santa Clara often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia