Book The Best Hotels in Santa Ana for 2026 from CA $27 - Fully Refundable Options

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Our top choices for Santa Ana hotels

1. Hotel Gran Colombia

Cuenca Historic Center

"Pues primero la reservacion no estaba al valor en la q salia en la aplicación, la habitación sonaba mucho el piso al caminar también sali del hotel a caminar por la noche y al regresar no habia quien nos apertura la puerta en la recepción, adicional cuando baje por el desayuno a las 8 y 45 me supieron decir q el hotel solo servía el desayuno hasta las 8 y 30 de la mañana pues para mi fue una pésima experiencia en el hotel por eso decidí retirarme al siguiente día"

Danny Daniel

CA $45

CA $45 total

Aug 17 - Aug 18

2. CASA TOMEBAMBA HOTEL & CONFORT

Huayna-Cápac

CA $49

CA $49 total

Aug 24 - Aug 25

3. Hotel NASS Continental

Downtown Cuenca

Donald

CA $45

CA $45 total

Aug 16 - Aug 17

42-inch Smart TV with digital channels, Netflix, first-run movies

Shower, rainfall showerhead, hair dryer (on request), towels

Deluxe Apartment, City View | Private kitchen

4. Hotel Apartment Cuenca

San Sebastián

CA $47

CA $47 total

Aug 16 - Aug 17

Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe

5. Arhaná Hostería Resort

Gualaceo

Juan

CA $97

CA $97 total

Aug 16 - Aug 17

6. Uzhupud Garden Hotel & lodge

Paute

Sonia

CA $183

CA $201 total

Aug 16 - Aug 17

42-inch Smart TV with cable channels, Netflix, streaming services

7. QUINTA MARIA ISABEL

Gualaceo

CA $67

CA $67 total

Aug 16 - Aug 17

8. Four Points By Sheraton Cuenca

Cuenca

Gisella

CA $144

CA $159 total

Aug 16 - Aug 17

Egyptian cotton sheets, premium bedding, in-room safe, desk

32-inch LED TV with premium channels, TV

9. TRYP by Wyndham Cuenca Zahir

Downtown Cuenca

Edison

CA $130

CA $143 total

Aug 21 - Aug 22

Outdoor pool, pool umbrellas, sun loungers

10. Oro Verde Cuenca

San Sebastián

Hector Alfredo

CA $139

CA $153 total

Aug 16 - Aug 17

11. Santa Lucia House - Forum

Downtown Cuenca

Marcela

CA $58

CA $64 total

Sep 14 - Sep 15

12. Naturhotel

Turi

Michelle Priscila

CA $82

CA $82 total

Sep 13 - Sep 14

13. Villa Ana Maria Cuenca

Cuenca

JUAN CARLOS

CA $150

CA $150 total

Aug 27 - Aug 28

14. Killary Lodge

Solano

maria elena

CA $161

CA $161 total

Aug 18 - Aug 19

Hot tub, steam room, hot springs, mud baths

15. Hosteria Durán

Banos

Alexandra

CA $167

CA $167 total

Aug 16 - Aug 17

16. Mansión Alcázar Boutique Hotel

Downtown Cuenca

Carlos

CA $111

CA $122 total

Sep 7 - Sep 8

17. El Dorado Hotel

Downtown Cuenca

Maria Fabiola

CA $111

CA $122 total

Aug 16 - Aug 17

2 restaurants; breakfast, lunch, and dinner served

18. Hotel Boutique Santa Lucia

Downtown Cuenca

Carla

CA $155

CA $170 total

Aug 16 - Aug 17

19. Rioné Hotel Boutique

Huayna-Cápac

Margot

CA $114

CA $128 total

Sep 15 - Sep 16

20. Vaway Hotel

Downtown Cuenca

David

CA $78

CA $78 total

Sep 15 - Sep 16

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Top Santa Ana Hotel Reviews

Santa Lucia Suites - Barranco

8/10 Good

"We liked the location of the property along the river; the bedroom was quiet and dark for a good night's sleep"

Vaway Hotel

10/10 Excellent

"Better than what I expected! So clean, so centrical, very good breakfast, spectacular view!! LOVE LOVE LOVE it!"

Hotel Italia Cuenca - Tranvía Centro y Aeropuerto

10/10 Excellent

"Close to the airport and bud terminal"

Casa Firenza

10/10 Excellent

"Loved our stayed at this hotel, highly recommended it if you’re traveling to Cuenca, Ecuador"

Hotel Boutique Santa Lucia

10/10 Excellent

"El personal muy atento y cordial. El hotel está muy bien situado en el centro de la ciudad."

Oro Verde Cuenca

8/10 Good

"The legendary Ecuadorian hospitality is fully alive at Hotel Oro Verde. Every single staff member was incredibly polite and prompt, but Edison truly stood out as a highlight of the trip. He was extraordinarily attentive and anticipated our needs before we even had to ask. Thank you, Edison, for your outstanding care and for making our stay feel seamless."

El Dorado Hotel

10/10 Excellent

"Buena ubicación y parqueadero conveniente, el personal atento y supo resolver problemas. Solo tomar en cuenta que el precio marcado en la plataforma no incluye el IVA del 15% si eres Ecuatoriano."

Santa Lucia House - Forum

10/10 Excellent

"A wonderful little hotel in the heart of Cuenca. The great staff, always welcoming and helpful makes us feel like family. The free breakfast never disappoints and free parking make the Forum a good value. This is our go to place when visiting Cuenca."

Mansión Alcázar Boutique Hotel

10/10 Excellent

"El hotel muy lindo y su encanto especial, lo único un poco incomodo la cama muy pequena"

More cheap stays in Santa Ana

Check Inn B&B - Hostel

General Torres 8-82 y Simon Bolivar Cuenca Azuay

CA $27

CA $27 total

Aug 16 - Aug 17

Hotel Apartment Cuenca

mariscal lamar 2550 y americas Cuenca Azuay

CA $47

CA $47 total

Aug 16 - Aug 17

Casa Sierra

Av. Manuel J Calle 2-100 Cuenca Azuay

CA $69

CA $69 total

Sep 15 - Sep 16

Saya Hotel & Suites

SAYAUSI AV ORDOÑEZ LASSO Sayausi Azuay

CA $81

CA $81 total

Sep 13 - Sep 14

Casa 11-24 by Casa Bolivar

Estévez de Toral Cuenca Azuay

CA $81

CA $81 total

Aug 22 - Aug 23

Miraflores Hotel Casa Blanca Cuenca

010150 Cuenca Azuay

Get rates

8/10 Very good! (1 review)

Frequently asked questions

What's the best place for a stay in Santa Ana?

Located 8.4 mi (13.5 km) from the heart of Santa Ana, Oro Verde Cuenca is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Four Points By Sheraton Cuenca and Vaway Hotel. See all available top hotels, or vacation rentals in Santa Ana.

What are some of the best vacation home rentals that Santa Ana has to offer?

Casa de lujo moderna y amplia: This vacation home rental near Santa Ana is equipped with a garden, laundry facilities, and free WiFi to help you feel comfortable during your stay. This vacation rental also comes with free parking to give you added peace of mind. See all vacation rentals in Santa Ana.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes, most room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Ana.

What is staying in Santa Ana like?

Visitors to Santa Ana are sure to find plenty to explore and enjoy. There are 427 hotels and other accommodations in the surrounding area. Find out more about Santa Ana.

What should I do while I'm visiting Santa Ana?

Places to visit in the wider area include Mirador de Turi, Puente Roto, and Alejandro Serrano Aguilar Stadium. You'll also find Río Tomebamba & Calle Larga and Plaza Rotary Market in the area. Check out what more to see and do in Expedia's Santa Ana guide.

What's the weather like in Santa Ana?

The hottest months are usually November and October with an average temp of 55°F, while the coldest months are July and August with an average of 52°F. The rainiest months in Santa Ana are April, March, February, and January, with each month seeing an average of 13 inches of rainfall.

Find hotels in Santa Ana from CA $27

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Santa Ana

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santa Ana hotels

1. Hotel Gran Colombia

2. CASA TOMEBAMBA HOTEL & CONFORT

3. Hotel NASS Continental

4. Hotel Apartment Cuenca

5. Arhaná Hostería Resort

6. Uzhupud Garden Hotel & lodge

7. QUINTA MARIA ISABEL

8. Four Points By Sheraton Cuenca

9. TRYP by Wyndham Cuenca Zahir

10. Oro Verde Cuenca

11. Santa Lucia House - Forum

12. Naturhotel

13. Villa Ana Maria Cuenca

14. Killary Lodge

15. Hosteria Durán

16. Mansión Alcázar Boutique Hotel

17. El Dorado Hotel

18. Hotel Boutique Santa Lucia

19. Rioné Hotel Boutique

20. Vaway Hotel

Top Santa Ana Hotel Reviews

Santa Lucia Suites - Barranco

Vaway Hotel

Hotel Italia Cuenca - Tranvía Centro y Aeropuerto

Casa Firenza

Hotel Boutique Santa Lucia

Oro Verde Cuenca

El Dorado Hotel

Santa Lucia House - Forum

Mansión Alcázar Boutique Hotel

More cheap stays in Santa Ana

Check Inn B&B - Hostel

Hotel Apartment Cuenca

Casa Sierra

Saya Hotel & Suites

Casa 11-24 by Casa Bolivar

Miraflores Hotel Casa Blanca Cuenca

Frequently asked questions

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