Title: Book the Best Piedmont SPA Resorts from CA $293 - Spa Hotels in Piedmont, SC | Expedia.ca [Hotels in Piedmont](https://expedia.ca/Piedmont-Hotels.d181440.Travel-Guide-Hotels)[Vacation Rentals in Piedmont](https://expedia.ca/Piedmont-Vacation-Rentals.d181440.Travel-Guide-VacationRentals)[Piedmont Car Rentals](https://expedia.ca/Car-Rentals-In-Piedmont.d181440.Car-Rental-Guide)[Piedmont Vacation Packages](https://expedia.ca/Piedmont.d181440.Destination-Travel-Guides) ![sunrise over the river](https://images.trvl-media.com/place/181440/8ffdff64-bee2-4dcb-bbeb-e453eb4216ae.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/181440/8ffdff64-bee2-4dcb-bbeb-e453eb4216ae.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Piedmont Spa Hotels Tonight [Apr 5 - Apr 6](https://www.expedia.ca/Hotel-Search?regionId=181440&startDate=2026-04-05&endDate=2026-04-06&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 6 - Apr 7](https://www.expedia.ca/Hotel-Search?regionId=181440&startDate=2026-04-06&endDate=2026-04-07&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=181440&startDate=2026-04-10&endDate=2026-04-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=181440&startDate=2026-04-17&endDate=2026-04-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Piedmont hotels with a spa ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-72054b06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6f048029.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/75814e45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection [](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) Greenville Downtown 9.6/10 Exceptional (470 reviews) - Escape to a Tudor retreat with a full-service spa and rooftop garden overlooking the scenic river in Greenville. CA $445 CA $503 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Couples treatment rooms, body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/0d84d9ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/4bf90c6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/32050804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d2844575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness [](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) Greenville 9.8/10 Exceptional (690 reviews) - Indulge in rejuvenating treatments at this upscale hotel with six couples spa rooms and scenic hiking trails for a peaceful escape. CA $224 CA $293 total includes taxes & fees Apr 26 - Apr 27 [](https://www.expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-20&endDate=2026-04-21®ionId=181440&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Choose what matters most at spa hotels in Piedmont Pool Breakfast included Hot tub 4 stars 5 stars ## Top Piedmont Hotel Reviews ![Drury Inn & Suites Greenville](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Hot tub was nice and beds were comfy " [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b0e15e12_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Clean and nice. " [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Comfort Suites Piedmont - Greenville South](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269961/3ff1bced_y.jpg) ### Comfort Suites Piedmont - Greenville South 8/10 Good "This is the second time we have stayed at this hotel. The first time we couldn’t get a handicap room because they said that they were working on the room and they had a water leak this time they give me a hearing accessible room but online I had ordered a handicap room then they told us that they only had one handicap room and that it was not available and we got aggravated and talked to them again and they said they didn’t have anything and we actually had a handicap room, even though it was just hearing accessible. so my husband told them we wouldn’t stay there anymore. Well, about 15 minutes later they come and knocked on our door and they had a handicap room for us right down the hall that was available the whole time but we were thankful the staff did accommodate us being that my mom is on a walker. The room was nice. The only complaint that I have was the bathtub which had rails was very slick. There was no way I would’ve put my mother in that tub. Other than that the room was great. " [](https://expedia.ca/Piedmont-Hotels-Comfort-Suites-Greenville-South.h17269961.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/8017eeff_y.jpg) ### Hilton Greenville 10/10 Excellent "Everything went smooth and the rooms were clean and spacious. The $10/night parking is a bit steep but what are you going to do " [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Piedmont? ### What's there to see and do in Piedmont? ### What is a Piedmont spa hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Hotels with a Pool in South Carolina ](https://www.expedia.ca/Destinations-In-South-Carolina-Hotel-With-Pool.0-0-d242-tHotelwithPool.Hotel-Filter-Destinations) - [Hotels with Balconies in South Carolina ](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Balconies.0-0-d242-tHotelswithBalconies.Hotel-Filter-Destinations) - [Hotels with Free Airport Shuttle in South Carolina ](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Free-Airport-Shuttle.0-0-d242-tHotelswithFreeAirportShuttle.Hotel-Filter-Destinations) - [Hotels with Free Breakfast in South Carolina ](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Free-Breakfast.0-0-d242-tHotelswithFreeBreakfast.Hotel-Filter-Destinations) - 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