Osco Vacation Rentals

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Vacation Rentals in Osco

Minutes from anywhere
10.0 out of 10, Exceptional, 67 reviews
"Grandsons high school graduation party. Worked out great. Very clean."
The price is CA $67
CA $117 total
includes taxes & fees
Jun 24 - Jun 25
Minutes from anywhere
Renwick Mansion Guest House
9.4 out of 10, Exceptional, 49 reviews
"The property fit our needs perfectly and allowed family to have room. The host was great."
Renwick Mansion Guest House
Island House On Mississippi River
8.2 out of 10, Very good, 23 reviews
"Nice location, nothing fancy, met our needs"
The price is CA $158
CA $285 total
includes taxes & fees
Jun 25 - Jun 26
Island House On Mississippi River
Lucy’s House Single Family Bungalow
9.8 out of 10, Exceptional, 26 reviews
"A quick stop while visiting my daughter’s future college. Loved Lucy’s place. So cozy, comfortable and clean. It was everything plus more that I could have asked for. Definitely will be staying again."
The price is CA $151
CA $151 total
includes taxes & fees
Jun 23 - Jun 24
Lucy’s House Single Family Bungalow
Quiet neighborhood surrounded by parks near multipurpose trail through QC
10.0 out of 10, Exceptional, 17 reviews
"Loved the property, felt like home to us and was super convenient for our family visit!"
Quiet neighborhood surrounded by parks near multipurpose trail through QC
Enjoy Florida in Illinois; House on Island with Pool
9.2 out of 10, Wonderful, 16 reviews
"We enjoyed our stay at this property. The house was spacious, the owner was responsive to our questions and it was a wonderful experience."
Enjoy Florida in Illinois; House on Island with Pool
Historic building on the Mississippi River
10.0 out of 10, Exceptional, 116 reviews
"We were looking for a calm and quite respite, and this checked the boxes! Property and furniture were clean and comfortable. And despite the heat, we were able to spend time on the shaded deck. We found ourselves choosing to stay in and enjoy the river, adding a cold drink and a good book, and we were set. 10 out of 10! Its not often mentioned in reviews, but we appreciated that the rental fees charged were not exorbitant. Its a beautifully preserved historical landmark, and we appreciate that...
Historic building on the Mississippi River
River Front House
8.2 out of 10, Very good, 10 reviews
"This property was a nice surprise. Especially the master bathroom. The view of the water and convenient location close to the bike trail was a great plus. Hope to stay again in the near future."
River Front House
Rustic and Secluded 1 Bedroom Cabin Retreat. Located on Private Stocked Pond.
10.0 out of 10, Exceptional, 10 reviews
"This property was amazing for my dogs and I! The property was well maintained with mowed walking trails that we took full advantage of! The pond was great for my puppy. All the swimming she did helped wear her out. I really appreciated the hose outside to spray her down after. The inside of the house was clean and cozy. It was well furnished with zero clutter. The shower head was amazing! I loved everything about this property! It was secluded and beautiful. I will definitely stay here...
Rustic and Secluded 1 Bedroom Cabin Retreat. Located on Private Stocked Pond.
River Front Views
10.0 out of 10, Exceptional, 9 reviews
"Fishing was the Best"
River Front Views
Scenic 1 Bedroom
9.8 out of 10, Exceptional, 35 reviews
"It was very nice and clean."
Scenic 1 Bedroom
🏡 Cottage in historic LeClaire. Dogs welcome + Fee 🐶 1 mi to downtown LeClaire
10.0 out of 10, Exceptional, 51 reviews
"Everything you could want - beautiful setting and great decks to sit out on! Two friendly black squirrels to watch even! Lol. Loved the place!"
The price is CA $259
CA $473 total
includes taxes & fees
Jun 24 - Jun 25
🏡 Cottage in historic LeClaire. Dogs welcome + Fee 🐶 1 mi to downtown LeClaire
Relaxing home to unwind
Relaxing home to unwind
Little Cabin on the Rock River - All your own!
9.6 out of 10, Exceptional, 8 reviews
"We loved it, the cabin is cute and cozy, the view of the river is so nice. We found a forest preserve close by and hiked, and just relaxed. It was much needed and we will be back!"
Little Cabin on the Rock River - All your own!
River Hideaway
9.8 out of 10, Exceptional, 7 reviews
"Everything was great. Will stay again!"
The price is CA $274
CA $527 total
includes taxes & fees
Jul 7 - Jul 8
River Hideaway
Riverview Hideaway/Downtown/East Village
Riverview Hideaway/Downtown/East Village
Le Claire Condo
10.0 out of 10, Exceptional, 11 reviews
"This property was everything and more that was listed on verbo. 2 blocks on the main street in Le Clare.If you don't mind walking the downtown area is about 1/2 mile walk.Weather was great we walked downtown twice."
Le Claire Condo
Hot Tub River Views
10.0 out of 10, Exceptional, 22 reviews
"Location, location, location. Bike trail by the front door and boat ramp (kayaking, fishing) in the back yard. Too fun. Super quiet as well."
Hot Tub River Views
Charming 1920s, pet friendly home, centrally located!
10.0 out of 10, Exceptional, 5 reviews
"We only spent 1 night but it suited our needs for the night and was nice. We have two teens that enjoyed having their own space with separate beds upstairs. It was a nice area and close to many things."
The price is CA $171
CA $320 total
includes taxes & fees
Jun 24 - Jun 25
Charming 1920s, pet friendly home, centrally located!
The river's edge on the Mississippi
10.0 out of 10, Exceptional, 106 reviews
"Perfect “school’s out for summer celebration” . Thanks again!"
The river's edge on the Mississippi
Don't see what you're looking for?
See all available properties in Osco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other types of properties in Osco you may be interested in

Stoney Creek Hotel Quad Cities - Moline
2.5 star property
8.4 out of 10, Very good, 1,003 reviews
"."
The price is CA $146
CA $167 total
includes taxes & fees
Jun 23 - Jun 24
Stoney Creek Hotel Quad Cities - Moline
Wyndham Moline on John Deere Commons
3.5 star property
9.0 out of 10, Wonderful, 1,001 reviews
"We used this property for a 3 day convention. It was a perfect location next to the convention center. We were able to catch a water taxi next to the property and for $8 was able to ride all day long. We stopped in Davenport for dinner. We were looking forward to using the hot tub, but was disappointed that it was mot working."
The price is CA $127
CA $144 total
includes taxes & fees
Jun 23 - Jun 24
Wyndham Moline on John Deere Commons
Isle Casino Hotel - Bettendorf
3.0 star property
8.2 out of 10, Very good, 1,001 reviews
"A stay! "
The price is CA $139
CA $175 total
includes taxes & fees
Jul 1 - Jul 2
Isle Casino Hotel - Bettendorf
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Everything you need to know about Osco vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Osco vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Osco vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Osco vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Osco. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Osco vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Osco vacation rentals we have selected for you start as low as per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Osco rentals

At Expedia, we put the best Osco vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Osco rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Osco vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Osco. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Can I find a vacation rental in Osco?

Yes, you can find vacation rentals near popular local attractions in Osco, or you can select a secluded option if you'd like a relaxing place to stay.

What are some of the best vacation home rentals in Osco?

Renwick Mansion Guest House: Visitors like this Osco vacation home rental. It offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

What’s there to see and do in Osco?

Explore the area and family-friendly sights such as Niabi Zoo, or get out into nature at a spot like Geneseo City Park. TPC Deere Run Golf Course and Deere and Company World Headquarters are a couple of places you'll find in the larger area.

What’s a vacation rental in Osco like?

Vacation rentals are privately owned properties you can stay in for short or long periods in Osco. Vacation rentals offer extras such as hot tubs, fire pits, and patios so you'll have a home away from home. If you're concerned about a sanitized environment, vacation rentals can provide a sense of safety away from public hotel elevators and busy concierge desks while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular choice for families.

Recent reviews of Osco properties
Expedia verified reviews