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Find hotels near North Mississippi Medical Center, Tupelo from CA $82

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    • Check prices for these dates

    Check prices for these dates, December 15–16, 2026

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    Our top choices for North Mississippi Medical Center hotels

    1. Baymont by Wyndham Tupelo

    A hotel room with a large bed, a wooden ceiling, a TV, a desk, and a bathroom visible in the background.

    2. La Quinta Inn & Suites by Wyndham Tupelo

    A spacious lobby with patterned seating, a stone accent wall, a flat-screen TV, and a snack bar.

    3. Red Roof Inn Tupelo

    A modern hotel lobby with a reception desk, an ATM, a dining area with chairs, and a kitchen area with a refrigerator.

    4. Hotel Tupelo, a Wyndham Hotel

    A modern lounge area with a neon sign, large windows, and a pool table.

    5. Holiday Inn Hotel & Suites Tupelo North by IHG

    A multi-level atrium with a central circular seating area, multiple dining tables, and a variety of seating options.

    6. Best Western Plus Tupelo Inn & Suites

    A hotel lobby with a reception desk, seating area with ottomans, and a patterned carpet.

    7. Tru By Hilton Tupelo

    A modern hotel lobby with a reception desk, seating area, and unique lighting fixtures.

    8. Holiday Inn Express Hotel & Suites Tupelo by IHG

    A Holiday Inn Express & Suites building with a prominent entrance, columns, and a clear sky.

    9. Comfort Inn Tupelo Central

    A hotel lobby with a reception desk, a small kitchenette, and a seating area with a coffee machine.

    10. Hilton Garden Inn Tupelo

    A hotel lobby with a reception desk, seating area, and a view of the outdoors.

    11. Home2 Suites By Hilton Tupelo, Ms

    An outdoor seating area with chairs and a fire pit, a brick building, and a clear sky.

    12. Studio 6 Suites Tupelo, MS - North

    A hotel entrance with a covered waiting area, a bench, and a car parking lot.

    13. Courtyard By Marriott Tupelo

    A Courtyard Marriott hotel entrance at night with a well-lit facade, a covered parking area, and a landscaped garden.

    14. Motel 6 Tupelo, MS - Downtown

    A hotel room with a bed, a desk with a flat-screen TV, a microwave, a sink, and a mirror.

    15. Quality Inn Tupelo Central

    A buffet area with various food options, a coffee machine, and a refrigerator.

    16. Candlewood Suites Tupelo North by IHG

    A multi-story hotel with a stone facade and a flat roof.

    17. Spark by Hilton Tupelo

    A modern, well-lit office space with multiple tables and chairs, a reception area, and large windows offering a view of greenery.

    18. Super 7 Inn Tupelo

    A room with a large window, a flat-screen TV, a table with chairs, and a potted plant.

    19. Hampton Inn & Suites Tupelo/Barnes Crossing

    A large indoor swimming pool with multiple seating areas and large windows.

    20. SureStay Hotel by Best Western Tupelo North

    A reception area with a wooden desk, a reception counter, a waiting area with brown upholstered chairs, a large window with a view of buildings, and a door marked "EXIT".

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Compare popular hotels close to North Mississippi Medical Center

    PropertyStar ratingGuest ratingBreakfast includedPoolSpaPet-friendlyWiFi included
    A modern lounge area with a neon sign, large windows, and a pool table.
    Hotel Tupelo, a Wyndham Hotel    		9.6Exceptional722 reviewsView
    A multi-level atrium with a central circular seating area, multiple dining tables, and a variety of seating options.
    Holiday Inn Hotel & Suites Tupelo North by IHG    		9.2Wonderful1,001 reviewsView
    A multi-story hotel with a stone facade and a flat roof.
    Candlewood Suites Tupelo North by IHG    		8.6Excellent479 reviewsView
    A hotel lobby with a reception desk, seating area, and a view of the outdoors.
    Hilton Garden Inn Tupelo    		8.0Very good1,001 reviewsView
    A hotel entrance with a covered waiting area, a bench, and a car parking lot.
    Studio 6 Suites Tupelo, MS - North    		7.2Good637 reviewsView

    Top North Mississippi Medical Center Hotel Reviews

    Holiday Inn Express Hotel & Suites Tupelo by IHG

    A Holiday Inn Express & Suites building with a prominent entrance, columns, and a clear sky.

    Holiday Inn Hotel & Suites Tupelo North by IHG

    A multi-level atrium with a central circular seating area, multiple dining tables, and a variety of seating options.

    Tru By Hilton Tupelo

    A modern hotel lobby with a reception desk, seating area, and unique lighting fixtures.

    La Quinta Inn & Suites by Wyndham Tupelo

    A spacious lobby with patterned seating, a stone accent wall, a flat-screen TV, and a snack bar.

    Hampton Inn & Suites Tupelo/Barnes Crossing

    A large indoor swimming pool with multiple seating areas and large windows.

    Best Western Plus Tupelo Inn & Suites

    A hotel lobby with a reception desk, seating area with ottomans, and a patterned carpet.

    Courtyard By Marriott Tupelo

    A Courtyard Marriott hotel entrance at night with a well-lit facade, a covered parking area, and a landscaped garden.

    Red Roof Inn Tupelo

    A modern hotel lobby with a reception desk, an ATM, a dining area with chairs, and a kitchen area with a refrigerator.

    Hilton Garden Inn Tupelo

    A hotel lobby with a reception desk, seating area, and a view of the outdoors.

    Spark by Hilton Tupelo

    A modern, well-lit office space with multiple tables and chairs, a reception area, and large windows offering a view of greenery.

    Comfort Inn Tupelo Central

    A hotel lobby with a reception desk, a small kitchenette, and a seating area with a coffee machine.

    Quality Inn Tupelo Central

    A buffet area with various food options, a coffee machine, and a refrigerator.

    Baymont by Wyndham Tupelo

    A hotel room with a large bed, a wooden ceiling, a TV, a desk, and a bathroom visible in the background.

    SureStay Hotel by Best Western Tupelo North

    A reception area with a wooden desk, a reception counter, a waiting area with brown upholstered chairs, a large window with a view of buildings, and a door marked "EXIT".

    Frequently Asked Questions

    What's the area like around North Mississippi Medical Center?

    North Mississippi Medical Center is located in a welcoming area of Tupelo known for its major shopping area. If you're looking for a convenient place to stay, check out the 7 hotels and other accommodations you'll find within a mile.

    What's the best hotel to stay close to North Mississippi Medical Center?

    Best Western Plus Tupelo Inn & Suites is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 3.9 mi (6.3 km) from North Mississippi Medical Center. Other good options within a few miles include Red Roof Inn Tupelo and Holiday Inn Hotel & Suites Tupelo North by IHG.

    How many hotels are there near North Mississippi Medical Center?

    Expedia has 7 hotels and other accommodations within a mile from North Mississippi Medical Center.

    If I need to cancel the hotel reservation for my stay near North Mississippi Medical Center, will I receive a refund?

    Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best options available near North Mississippi Medical Center.

    Where can I learn more about changing or cancelling my trip in the area near North Mississippi Medical Center?

    For more information about rescheduling or cancelling your stay near North Mississippi Medical Center, click here.

    What can I see and do near North Mississippi Medical Center?

    You'll want to browse the exhibits at Elvis Presley Center and Oren Dunn City Museum. You might spend a leisurely day outdoors at Ballard Park and Elvis Presley Lake and Campground. Stopping by Cadence Bank Arena, Rob Leake City Park Tennis Center, or Cinemark Tupelo Movies 8 is a fun way to see all the area has to offer.

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