Title: The 10 Best Hotels Near North Mississippi Medical Center, Tupelo from CA $77 | Expedia.ca [Tupelo Travel Guide](https://expedia.ca/Tupelo.dx6058686)[Vacation Rentals in Tupelo](https://expedia.ca/Tupelo-Vacation-Rentals.d6058686.Travel-Guide-VacationRentals)[Flights to Tupelo](https://expedia.ca/Cheap-Flights-To-Tupelo.d6058686.Travel-Guide-Flights)[North Mississippi Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-North-Mississippi-Medical-Center.d6140198.Car-Rental-Guide)[North Mississippi Medical Center Vacations](https://expedia.ca/North-Mississippi-Medical-Center-Tupelo.d6140198.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near North Mississippi Medical Center, Tupelo from CA $77 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 12 - Dec 13](https://www.expedia.ca/Hotel-Search?regionId=6140198&startDate=2025-12-12&endDate=2025-12-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6140198&startDate=2025-12-13&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6140198&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6140198&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for North Mississippi Medical Center hotels ![Restaurant](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/2dd2ec4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/058dab58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/5e403676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/564eab06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Tupelo, a Wyndham Hotel [](https://www.expedia.ca/Tupelo-Hotels-Hotel-Tupelo.h73081348.Hotel-Information) 2.2 km from North Mississippi Medical Center 9.6/10 Exceptional (580) "Very nice property with friendly, helpful staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $247 CA $270 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Tupelo-Hotels-Hotel-Tupelo.h73081348.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/c2002907.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/8d0dca5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/5cc46626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/0b405f3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Hotel & Suites Tupelo North by IHG [](https://www.expedia.ca/Tupelo-Hotels-Holiday-Inn-Hotel-Suites-Tupelo-North.h3885.Hotel-Information) 3 km from North Mississippi Medical Center 9.2/10 Wonderful (1001) "Room was great very nice hotel, restaurant fantastic!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hailie CA $154 CA $169 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Tupelo-Hotels-Holiday-Inn-Hotel-Suites-Tupelo-North.h3885.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513705/2ecf5fc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513705/38bad4d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513705/c9aef1ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513705/5607cbfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Hilton-Garden-Inn-Tupelo.h1513705.Hotel-Information) 2.3 km from North Mississippi Medical Center 8.2/10 Very good (1001) "Clean room, friendly staff. Breakfast was outstanding " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah CA $142 CA $155 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Tupelo-Hotels-Hilton-Garden-Inn-Tupelo.h1513705.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5970000/5966400/5966360/7e36aedb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/6000000/5970000/5966400/5966360/f994ff60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/6000000/5970000/5966400/5966360/3b120605.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom (1 King)](https://images.trvl-media.com/lodging/6000000/5970000/5966400/5966360/5fcd6a7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Tupelo North by IHG [](https://www.expedia.ca/Tupelo-Hotels-Candlewood-Suites-Tupelo-North.h5966360.Hotel-Information) 3 km from North Mississippi Medical Center 8.6/10 Excellent (435) "Excellent stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda CA $145 CA $158 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Tupelo-Hotels-Candlewood-Suites-Tupelo-North.h5966360.Hotel-Information) ![Premium bedding, laptop workspace, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/4000000/3880000/3874700/3874642/5526317f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3880000/3874700/3874642/71a98cb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/4000000/3880000/3874700/3874642/51df6656.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, laptop workspace, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/4000000/3880000/3874700/3874642/5808ace1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Tupelo North [](https://www.expedia.ca/Tupelo-Hotels-SureStay-Hotel-By-Best-Western-Tupelo-North.h3874642.Hotel-Information) 2.8 km from North Mississippi Medical Center 7.4/10 Good (243) "Property was clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $81 CA $88 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Tupelo-Hotels-SureStay-Hotel-By-Best-Western-Tupelo-North.h3874642.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/235e5b9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/ad450c51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/b9c3ac33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/a4d90b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 Suites Tupelo, MS - North [](https://www.expedia.ca/Tupelo-Hotels-Clarion-Inn-And-Summit-Center.h1765320.Hotel-Information) 3.1 km from North Mississippi Medical Center 7.4/10 Good (524) "Everything was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jakeeta CA $70 CA $77 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Tupelo-Hotels-Clarion-Inn-And-Summit-Center.h1765320.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1440000/1431700/1431624/4e2b5866.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1440000/1431700/1431624/93c395e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1440000/1431700/1431624/6de4497e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually furnished, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1440000/1431700/1431624/0f33b6c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Tupelo, MS - Downtown [](https://www.expedia.ca/Tupelo-Hotels-Motel-6-Tupelo.h1431624.Hotel-Information) 3 km from North Mississippi Medical Center 6.8/10 (265) "The " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tammy CA $83 CA $90 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Tupelo-Hotels-Motel-6-Tupelo.h1431624.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/910000/903500/903414/0a336343.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/903500/903414/284d5d0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/903500/903414/01226df3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/903500/903414/4cab39f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Scottish Inns [](https://www.expedia.ca/Tupelo-Hotels-Scottish-Inns.h903414.Hotel-Information) 2 km from North Mississippi Medical Center 5.6/10 (92) "Awesome beds and quite " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $83 CA $90 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Tupelo-Hotels-Scottish-Inns.h903414.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/f02717f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/6902bc3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/23557130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/5ba41635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Tupelo by IHG [](https://www.expedia.ca/Tupelo-Hotels-Holiday-Inn-Express-Hotel-Suites-Tupelo.h977294.Hotel-Information) 4.1 km from North Mississippi Medical Center 9.4/10 Exceptional (1001) "Great staff!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory CA $145 CA $158 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Tupelo-Hotels-Holiday-Inn-Express-Hotel-Suites-Tupelo.h977294.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/8419c524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/ceef32e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/b0ef1168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Hearing)](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/819e1941.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Tru-By-Hilton-Tupelo.h72278514.Hotel-Information) 4.4 km from North Mississippi Medical Center 9.2/10 Wonderful (635) "Very clean room and staff very attentive and friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emily CA $127 CA $138 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Tupelo-Hotels-Tru-By-Hilton-Tupelo.h72278514.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/5221b566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/95988947.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/3e72a44d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/ca43d022.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Red-Roof-Inn-Tupelo.h16073.Hotel-Information) 3.6 km from North Mississippi Medical Center 8.4/10 Very good (1000) "Older motel, but very clean and maintained. We were just there one night, but the bed was comfortable and the room was warm. Would certainly stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marvin Kelly [](https://www.expedia.ca/Tupelo-Hotels-Red-Roof-Inn-Tupelo.h16073.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/3bb6afaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/4c593757.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/5f491de5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/4e4a90da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Tupelo [](https://www.expedia.ca/Tupelo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tupelo.h3025105.Hotel-Information) 3.6 km from North Mississippi Medical Center 8.6/10 Excellent (1000) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Winston CA $121 CA $132 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Tupelo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tupelo.h3025105.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/71000000/70050000/70048200/70048190/c0a90d2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily local cuisine breakfast](https://images.trvl-media.com/lodging/71000000/70050000/70048200/70048190/10f31eb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bed sheets](https://images.trvl-media.com/lodging/71000000/70050000/70048200/70048190/57a53400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/71000000/70050000/70048200/70048190/9c44a4c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites By Hilton Tupelo, Ms [](https://www.expedia.ca/Tupelo-Hotels-Home2-Suites-By-Hilton-Tupelo.h70048190.Hotel-Information) 4.3 km from North Mississippi Medical Center 9.4/10 Exceptional (373) "Clean and stocked room, awesome breakfast, and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason CA $149 CA $163 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Tupelo-Hotels-Home2-Suites-By-Hilton-Tupelo.h70048190.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116523/0ca0a097.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/120000/116600/116523/5809c860.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/120000/116600/116523/e6fee54f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/120000/116600/116523/6fda8620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Tupelo Central [](https://www.expedia.ca/Tupelo-Hotels-Comfort-Inn.h116523.Hotel-Information) 3.6 km from North Mississippi Medical Center 8.2/10 Very good (1002) "It was close to the hospital " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mohammed CA $97 CA $106 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Tupelo-Hotels-Comfort-Inn.h116523.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/50000/42300/42285/dcc3bdc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/50000/42300/42285/fa554ca2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/50000/42300/42285/9b913320.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42300/42285/91ff0b45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard By Marriott Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Courtyard-By-Marriott-Tupelo.h42285.Hotel-Information) 3.9 km from North Mississippi Medical Center 8.4/10 Very good (311) "Good experience, will stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lamont CA $166 CA $182 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Tupelo-Hotels-Courtyard-By-Marriott-Tupelo.h42285.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/a4930614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/c3a3359c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/2660a6de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/e630b24b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Tupelo Central [](https://www.expedia.ca/Tupelo-Hotels-Quality-Inn.h21594.Hotel-Information) 4 km from North Mississippi Medical Center 7.8/10 Good (520) "The room was nice and the breakfast was outstanding!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terry CA $73 CA $79 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Tupelo-Hotels-Quality-Inn.h21594.Hotel-Information) ![Indoor pool, open 11:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/97b5a707.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 1 King Bed, Non Smoking, Pool View](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/w2999h2000x0y0-850de2b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/5320e349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/e8f7cbcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Baymont-By-Wyndham-Tupelo.h124475.Hotel-Information) 4.2 km from North Mississippi Medical Center 7.6/10 Good (1001) "Everything was great.. location was awesome as well " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Archie CA $81 CA $88 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Tupelo-Hotels-Baymont-By-Wyndham-Tupelo.h124475.Hotel-Information) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/30000/23300/23221/b694ac45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23300/23221/f6b80560.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23300/23221/329e3e8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/23300/23221/0a918b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Days-Inn-By-Wyndham-Tupelo.h23221.Hotel-Information) 3.6 km from North Mississippi Medical Center 6.8/10 (354) "Rooms were clean and customer service was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melinda CA $79 CA $86 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Tupelo-Hotels-Days-Inn-By-Wyndham-Tupelo.h23221.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/539500/539490/6524fbce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/539500/539490/27ebce81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/540000/539500/539490/93f281e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/540000/539500/539490/c535dc76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Tupelo Barnes Crossing [](https://www.expedia.ca/Tupelo-Hotels-Econolodge-Tupelo.h539490.Hotel-Information) 7 km from North Mississippi Medical Center 6.6/10 (387) "Clean room. Good stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $70 CA $77 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Tupelo-Hotels-Econolodge-Tupelo.h539490.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/2eb203b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/f27f3041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/b6f62c46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/e355fdf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Tupelo Inn & Suites [](https://www.expedia.ca/Tupelo-Hotels-Best-Western-Plus-Tupelo-Inn-Suites.h4537402.Hotel-Information) 6.3 km from North Mississippi Medical Center 8.6/10 Excellent (1001) "Great location next to shopping " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) roy CA $134 CA $146 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Tupelo-Hotels-Best-Western-Plus-Tupelo-Inn-Suites.h4537402.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-27®ionId=6140198&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top North Mississippi Medical Center Hotel Reviews ![Comfort Inn Tupelo Central](https://images.trvl-media.com/lodging/1000000/120000/116600/116523/0ca0a097_y.jpg) ### Comfort Inn Tupelo Central 10/10 Excellent "Excellent stay, friendly staff, clean room, great breakfast food." [](https://expedia.ca/Tupelo-Hotels-Comfort-Inn.h116523.Hotel-Information) ![Home2 Suites By Hilton Tupelo, Ms](https://images.trvl-media.com/lodging/71000000/70050000/70048200/70048190/c0a90d2b_y.jpg) ### Home2 Suites By Hilton Tupelo, Ms 10/10 Excellent "Clean and great breakfast!" [](https://expedia.ca/Tupelo-Hotels-Home2-Suites-By-Hilton-Tupelo.h70048190.Hotel-Information) ![Tru By Hilton Tupelo](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/8419c524_y.jpg) ### Tru By Hilton Tupelo 10/10 Excellent "Fun atmosphere, clean rooms, comfortable beds" [](https://expedia.ca/Tupelo-Hotels-Tru-By-Hilton-Tupelo.h72278514.Hotel-Information) ![Super 7 Inn Tupelo](https://images.trvl-media.com/lodging/1000000/30000/28300/28201/5d762157_y.jpg) ### Super 7 Inn Tupelo 10/10 Excellent "Nice" [](https://expedia.ca/Tupelo-Hotels-Super-7-Inn.h28201.Hotel-Information) ![Quality Inn Tupelo Central](https://images.trvl-media.com/lodging/1000000/30000/21600/21594/a4930614_y.jpg) ### Quality Inn Tupelo Central 10/10 Excellent "Good stay" [](https://expedia.ca/Tupelo-Hotels-Quality-Inn.h21594.Hotel-Information) ![Best Western Plus Tupelo Inn & Suites](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/2eb203b9_y.jpg) ### Best Western Plus Tupelo Inn & Suites 10/10 Excellent "front desk very nice clean room" [](https://expedia.ca/Tupelo-Hotels-Best-Western-Plus-Tupelo-Inn-Suites.h4537402.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Tupelo](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/3bb6afaf_y.jpg) ### La Quinta Inn & Suites by Wyndham Tupelo 10/10 Excellent "Friendly staff, clean room with comfortable bed" [](https://expedia.ca/Tupelo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tupelo.h3025105.Hotel-Information) ![Baymont by Wyndham Tupelo](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/97b5a707_y.jpg) ### Baymont by Wyndham Tupelo 10/10 Excellent "Everything was top notch!! Clean, friendly staff and breakfast was good " [](https://expedia.ca/Tupelo-Hotels-Baymont-By-Wyndham-Tupelo.h124475.Hotel-Information) ![Hotel Tupelo, a Wyndham Hotel](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/2dd2ec4e_y.jpg) ### Hotel Tupelo, a Wyndham Hotel 10/10 Excellent "Very nice property with friendly, helpful staff" [](https://expedia.ca/Tupelo-Hotels-Hotel-Tupelo.h73081348.Hotel-Information) ## Hotels near other North Mississippi Medical Center attractions ### Tupelo Buffalo Park 4.0/5 (71 reviews) Why not see the exotic and native animals who live at Tupelo Buffalo Park during your travels in Tupelo? Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655102) ### Tupelo National Battlefield 3.8/5 (66 reviews) Explore the great outdoors at Tupelo National Battlefield, a lovely green space in Tupelo. While you're in the area, find time to visit its shops. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6092633) ### BancorpSouth Arena 4.3/5 (151 reviews) Catch an event at BancorpSouth Arena during your trip to Tupelo. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6092629) ### Rob Leake City Park Tennis Center Catch an event at Rob Leake City Park Tennis Center during your trip to Tupelo. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=941624716639272960) ### Ballard Park 4.2/5 (110 reviews) Explore the great outdoors at Ballard Park, a lovely green space in Tupelo. While you're in the area, find time to visit its shops. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655097) ### Elvis Presley Center 4.2/5 (168 reviews) You can spend time studying the exhibits at Elvis Presley Center during your travels in Tupelo. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655101) ### Oren Dunn City Museum 3.7/5 (19 reviews) You can spend time studying the exhibits at Oren Dunn City Museum during your trip to Tupelo. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655096) ### Elvis Presley Lake and Campground 4.1/5 (51 reviews) Explore the great outdoors at Elvis Presley Lake and Campground, a lovely green space in Tupelo. While you're in the area, find time to visit its shops. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532655103) ## Frequently asked questions ### What's the area like around North Mississippi Medical Center? ### What's the best hotel to stay close to North Mississippi Medical Center? ### How many hotels are there near North Mississippi Medical Center? ### If I need to cancel the hotel reservation for my stay near North Mississippi Medical Center, will I receive a refund? ### What can I see and do near North Mississippi Medical Center? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Aberdeen Hotels ](https://www.expedia.ca/Aberdeen-Hotels.d10650.Travel-Guide-Hotels) - [Amory Hotels ](https://www.expedia.ca/Amory-Hotels.d183443.Travel-Guide-Hotels) - [Anchor Hotels ](https://www.expedia.ca/Anchor-Hotels.d553248635975848560.Travel-Guide-Hotels) - [Hotels near BancorpSouth Arena ](https://www.expedia.ca/BancorpSouth-Arena-Hotels.0-l6092629-0.Travel-Guide-Filter-Hotels) - 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