An ancient stone corridor with arches, potted plants, and a dome structure in the background.

Find Spa Hotels in Mission, TX from CA $261

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Check availability on Mission Spa Hotels

Next weekend
Nov 6 - Nov 8
In two weeks
Nov 13 - Nov 15

Our top choices for Mission hotels with a spa

A modern dining area with white tables and purple chairs, a kitchen in the background, and a patterned rug on the floor.

1. La Quinta Inn & Suites by Wyndham Mission at West McAllen

La Quinta Inn & Suites by Wyndham Mission at West McAllen
3.0 star property
Mission
8.6 out of 10, Excellent, (1,047 reviews)
"Had a great stay, will be booking again if in the area."
United States
James
The price is CA $112
CA $126 total
includes taxes & fees
Nov 13 - Nov 14
La Quinta Inn & Suites by Wyndham Mission at West McAllen
A swimming pool with a covered area, a fence, and a building with a sign in the background.

2. SureStay Hotel By Best Western Mission

SureStay Hotel By Best Western Mission
2.5 star property
Mission
8.2 out of 10, Very good, (901 reviews)
"Great stay"
United States
Angelica
The price is CA $63
CA $71 total
includes taxes & fees
Nov 8 - Nov 9
SureStay Hotel By Best Western Mission
A compact hotel room with a dark wood desk, a chair, a large mirror, a flat-screen TV mounted on the wall, and a door leading to another room.

3. Motel 6 Mission, TX

Motel 6 Mission, TX
2.0 star property
Mission
8.8 out of 10, Excellent, (1,274 reviews)
"Excelente"
Mexico
Carlos
The price is CA $70
CA $80 total
includes taxes & fees
Nov 3 - Nov 4
Motel 6 Mission, TX
A hotel lobby with a reception desk, a dining area, and a seating area with a green chair.

4. Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG

Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG
2.5 star property
Mission
9.2 out of 10, Wonderful, (1,004 reviews)
"Clean, quiet rooms and friendly staff"
United States
Mekila
The price is CA $109
CA $123 total
includes taxes & fees
Nov 5 - Nov 6
Holiday Inn Express Hotel & Suites Mission-McAllen Area by IHG
A hotel reception area with a counter, a wall sign reading 'Welcome to Hampton,' and a sign for 'Treats' with snacks and sundries.

5. Hampton Inn & Suites Mission

Hampton Inn & Suites Mission
3.0 star property
Mission
9.4 out of 10, Exceptional, (61 reviews)
"Liked the location, rooms were clean and very friendly service."
United States
Ruben
The price is CA $125
CA $142 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn & Suites Mission
A modern living room with a beige sofa, two armchairs, and a wooden coffee table.

6. The Bungalows on Shary, Mission-McAllen

The Bungalows on Shary, Mission-McAllen
2.5 star property
Mission
9.0 out of 10, Wonderful, (1,003 reviews)
"Such a beautiful location"
United States
anna
The price is CA $138
CA $156 total
includes taxes & fees
Nov 4 - Nov 5
The Bungalows on Shary, Mission-McAllen
An outdoor seating area with wicker furniture, a fire feature, and a covered patio.

7. avid hotel Mission East - McAllen Area by IHG

avid hotel Mission East - McAllen Area by IHG
2.0 star property
Mission
9.0 out of 10, Wonderful, (114 reviews)
"The room was very spacious and clean. The staff were extremely friendly. Lots of restaurants and shops nearby. The only downside was I had no chair in my room to sit on, only the bed. Very pleasant stay and affordable price. Would definitely recommend a stay at this hotel."
United States
Robert
The price is CA $98
CA $111 total
includes taxes & fees
Nov 8 - Nov 9
avid hotel Mission East - McAllen Area by IHG
A spacious hotel lobby with a high ceiling, a staircase, and a seating area with a blue sofa and a coffee table.

8. Comfort Inn Mission - McAllen West

Comfort Inn Mission - McAllen West
2.5 star property
Mission
8.6 out of 10, Excellent, (416 reviews)
"Everything was great, couldn't have asked for better"
United States
GLORIA
The price is CA $100
CA $113 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn Mission - McAllen West
An outdoor seating area with wicker furniture, a fire feature, and a covered patio.

9. Candlewood Suites Mission East Mcallen Area by IHG

Candlewood Suites Mission East Mcallen Area by IHG
2.5 star property
Mission
9.0 out of 10, Wonderful, (34 reviews)
"The rooms were a great size with a small kitchenette and small refrigerator. The hotel was immaculate, the beds were very comfortable, and the water pressure was great with plenty of hotel water. The hotel is a little pricey since it is right next to the Mission Event Center but the location was great"
United States
Thomas
The price is CA $177
CA $201 total
includes taxes & fees
Nov 15 - Nov 16
Candlewood Suites Mission East Mcallen Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Mission

Pool
Breakfast included

Top Mission Hotel Reviews

Frequently asked questions

How much does a spa hotel in Mission cost?
Enjoy staying in a spa hotel in Mission, with plenty of hotels from CA $261 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, and may vary depending on the location, season, and hotel amenities. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during the weekend or around public holidays.
Is it cheaper to book a spa hotel in Mission with flights as part of a package deal?
Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package.
Are there any unique spa experiences available in Mission?
Yes, Mission, Texas offers several unique spa experiences, particularly through specialized and holistic services.

Mission Day Spa provides oncology-trained spa treatments specifically designed for solo travellers undergoing or recovering from cancer treatments. Their offerings include oncology facials, gentle therapeutic massages, lymphatic support, and Ayurvedic holistic care, all aimed at safe, healing, and restorative wellness in a calm, supportive environment.

Additionally, other spas in Mission, such as Mio Momento Dermatology Spa, Zuluxury Spa, NDO Spa, Twinkle Toes Nails & Spa, and Sugaring NYC, offer a variety of massage and beauty treatments.
Can I cancel my spa hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right spa hotel in Mission for you.
How can I save on a spa hotel in Mission with Expedia?
Find Mission spa hotel deals by joining One Key™, Expedia's free travel rewards program. As a member, you can unlock instant savings with Member Prices when you're logged in. For a quick weekend retreat, discover last-minute offers.

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