Hotel Milano Navigli is located in the heart of Milano, and perfect for accessing all the major parts of the city. The Duomo is a short walk away, and the robust transit system means you can get anywhere you need to be efficiently. The Front Desk staff are friendly and attentive, and if you expect to be doing a lot of sightseeing or conference work, this is the place for you.
A major downside to the property is sound proofing, in particular the interior sound proofing. While the room was extremely quiet in the evenings, with only the occasional hum of a nearby tram, your experience may differ depending on the scheduling of staff or other guests. I was awoken nearly every morning to a din of cleaning staff going about their business, often starting at 6:00 and running until 14:00. While I do not fault the cleaning staff for doing their work, it was more than disruptive, and I found myself unable to get a good night's rest if I had a late night.
When we arrived there were clearly some surfaces that were not cleaned or dusted, but nothing seriously outstanding. A big plus was the care package in the bathroom, containing basically any toiletry you'd require. While we brought our own, it was extremely well stocked and worthy of note.
If you are okay with some noisiness within the hotel's interior, you'll be hard pressed to beat the sheer convenience of the hotel's location for a similar price, and I'd likely return in the future all things considered.