Title: The 10 Best Hotels Near Mercy Hospital Jefferson, from CA $111 | Expedia.ca [Missouri Travel Guide](https://expedia.ca/Missouri.dx227)[Vacation Rentals in Missouri](https://expedia.ca/Destinations-In-Missouri.d227.Vacation-Rental-Destinations)[Flights to Missouri](https://expedia.ca/Destinations-In-Missouri.d227.Flight-Destinations)[Things to do in Missouri](https://expedia.ca/Things-To-Do-In-Missouri.d227.Travel-Guide-Activities)[Mercy Hospital Jefferson Car Rentals](https://expedia.ca/Car-Rentals-In-Mercy-Hospital-Jefferson.d624556129857114112.Car-Rental-Guide)[Mercy Hospital Jefferson Vacations](https://expedia.ca/Mercy-Hospital-Jefferson-Missouri.d624556129857114112.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Apr 8 - Apr 9](https://www.expedia.ca/Hotel-Search?regionId=624556129857114112&startDate=2026-04-08&endDate=2026-04-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 9 - Apr 10](https://www.expedia.ca/Hotel-Search?regionId=624556129857114112&startDate=2026-04-09&endDate=2026-04-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=624556129857114112&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=624556129857114112&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Mercy Hospital Jefferson hotels ![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/4e70ae9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed (Wet Bar)](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/ef5769f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/w7137h4758x0y0-7ae60078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/d2d65c58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG [](https://www.expedia.ca/Farmington-Hotels-Holiday-Inn-Express-Hotel-Suites-FESTUS-SOUTH-ST-LOUIS.h2699317.Hotel-Information) 2 km from Mercy Hospital Jefferson 9.4/10 Exceptional (720 reviews) "We have stayed at this location a few times and definitely will be back" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $200 CA $228 total includes taxes & fees Apr 19 - Apr 20 [](https://www.expedia.ca/Farmington-Hotels-Holiday-Inn-Express-Hotel-Suites-FESTUS-SOUTH-ST-LOUIS.h2699317.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/6e70629c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/e9e97147.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/1887aa70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/a1c40704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Festus - St. Louis South [](https://www.expedia.ca/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information) 2.1 km from Mercy Hospital Jefferson 8.0/10 Very good (951 reviews) "All was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laureen CA $140 CA $160 total includes taxes & fees Apr 19 - Apr 20 [](https://www.expedia.ca/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/26be907b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/fc42ec39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![6 bedrooms, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/5e88cbc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/2ffc9c16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Festus - St Louis South [](https://www.expedia.ca/Farmington-Hotels-Comfort-Inn-Festus-St-Louis-South.h40138.Hotel-Information) 2.3 km from Mercy Hospital Jefferson 7.8/10 Good (929 reviews) "Staff was very friendly and the room was very comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lanae CA $110 CA $128 total includes taxes & fees Apr 30 - May 1 [](https://www.expedia.ca/Farmington-Hotels-Comfort-Inn-Festus-St-Louis-South.h40138.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/b5436bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Festus [](https://www.expedia.ca/Festus-Hotels-Baymont-By-Wyndham-Festus.h5523.Hotel-Information) 1.7 km from Mercy Hospital Jefferson 6.8/10 (952 reviews) "Love this place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monica CA $97 CA $111 total includes taxes & fees Apr 19 - Apr 20 [](https://www.expedia.ca/Festus-Hotels-Baymont-By-Wyndham-Festus.h5523.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/126000000/125890000/125884400/125884343/2b0fdc16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast](https://images.trvl-media.com/lodging/126000000/125890000/125884400/125884343/9db689f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/126000000/125890000/125884400/125884343/3ff3ca9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/126000000/125890000/125884400/125884343/f0c18168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites By Wyndham Festus [](https://www.expedia.ca/Festus-Hotels-Days-Inn-Suites-By-Wyndham-Festus.h125884343.Hotel-Information) 1.6 km from Mercy Hospital Jefferson 3.6/10 (5 reviews) "This hotel is in the middle of a remodel. The front desk staff was very helpful and expedient. We stayed on the 4th floor and entered through a side door. The hallway was recently painted but the new floor was filthy. Our room was recently remodeled. The floor was very dirty And the bathroom floor was so bad I put towels down as I didn't want to walk on it in my bare feet. I would avoid this hotel until the remodel is finished. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah CA $112 CA $128 total includes taxes & fees Apr 9 - Apr 10 [](https://www.expedia.ca/Festus-Hotels-Days-Inn-Suites-By-Wyndham-Festus.h125884343.Hotel-Information) ![Desk, laptop workspace, blackout drapes, rollaway beds](https://images.trvl-media.com/lodging/1000000/860000/856200/856190/c6ce0eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 10:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/860000/856200/856190/31887483.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/860000/856200/856190/966cfbcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856200/856190/e41ca8e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Pevely [](https://www.expedia.ca/Farmington-Hotels-Super-8-By-Wyndham-Pevely.h856190.Hotel-Information) 10.1 km from Mercy Hospital Jefferson 5.6/10 (843 reviews) "Mold in room, hole in wall, dirty sheets, smelt musty. Breakfast server cold biscuits and watered down meatless gravy, warm milk and a broken juice machine. Save the suffering and sleep in you car or keep driving" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ryan CA $109 CA $126 total includes taxes & fees Apr 16 - Apr 17 [](https://www.expedia.ca/Farmington-Hotels-Super-8-By-Wyndham-Pevely.h856190.Hotel-Information) ![Dave & Mayme's Whirlpool Suite](https://images.trvl-media.com/lodging/7000000/6060000/6058000/6057984/5d468a79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/7000000/6060000/6058000/6057984/e5e9cafa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![McRoberts Room](https://images.trvl-media.com/lodging/7000000/6060000/6058000/6057984/f44f88b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Summer Kitchen](https://images.trvl-media.com/lodging/7000000/6060000/6058000/6057984/2e949a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Corner George Inn Bed & Breakfast [](https://www.expedia.ca/Maeystown-Hotels-Corner-George-Inn-Bed-Breakfast.h6057984.Hotel-Information) 14.3 km from Mercy Hospital Jefferson 9.0/10 Wonderful (154 reviews) "Hosts were excellent, very quiet and the breakfast was wonderful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $164 CA $182 total includes taxes & fees Apr 11 - Apr 12 [](https://www.expedia.ca/Maeystown-Hotels-Corner-George-Inn-Bed-Breakfast.h6057984.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-22&endDate=2026-04-23®ionId=624556129857114112&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Mercy Hospital Jefferson | Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/4e70ae9a.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG | 2.5 star property | 9.4Exceptional720 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/6e70629c.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)La Quinta Inn & Suites by Wyndham Festus - St. Louis South | 3.0 star property | 8.0Very good951 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/26be907b.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Comfort Inn Festus - St Louis South | 2.5 star property | 7.8Good929 reviews | View | | | | | | | ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/b5436bf6.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Baymont by Wyndham Festus | 3.0 star property | 6.8952 reviews | View | | | | | | | ![Reception](https://images.trvl-media.com/lodging/126000000/125890000/125884400/125884343/2b0fdc16.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Days Inn & Suites By Wyndham Festus | 2.0 star property | 3.65 reviews | View | | | | | | ## Top Mercy Hospital Jefferson Hotel Reviews ![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/b53f4594_y.jpg) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham 10/10 Excellent "Nice room, comfortable bed, good breakfast." [](https://expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) ![Baymont by Wyndham Festus](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/b5436bf6_y.jpg) ### Baymont by Wyndham Festus 6/10 Okay "Room was clean enough, but bed was too hard. Rooms are old and in need updates. Changed rooms two times due to broken lock and then non stop barking dogs in room next to us. Last room had no hanging bar in closet so no way to keep clothes hung. Parking lot covered with litter. During the early morning, workers making a lot of noise overhead. Overall, okay for the price, but won't stay there again. " [](https://expedia.ca/Festus-Hotels-Baymont-By-Wyndham-Festus.h5523.Hotel-Information) ![Pear Tree Inn St. Louis Arnold](https://images.trvl-media.com/lodging/1000000/50000/40200/40112/d33a8d98_y.jpg) ### Pear Tree Inn St. Louis Arnold 8/10 Good "Nice and clean close to a lot of businesses" [](https://expedia.ca/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Arnold.h40112.Hotel-Information) ![River City Casino & Hotel](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/71580e9e_y.jpg) ### River City Casino & Hotel 10/10 Excellent "Water pressure was amazing " [](https://expedia.ca/St-Louis-Hotels-River-City-Casino-Hotel.h6456459.Hotel-Information) ![Best Western St. Louis Inn](https://images.trvl-media.com/lodging/1000000/70000/63700/63684/6581bcc5_y.jpg) ### Best Western St. Louis Inn 10/10 Excellent "Friendly staff " [](https://expedia.ca/St-Louis-Hotels-Best-Western-St-Louis-Inn.h63684.Hotel-Information) ![Comfort Inn Festus - St Louis South](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/26be907b_y.jpg) ### Comfort Inn Festus - St Louis South 10/10 Excellent "Very adequate. Room was very clean and breakfast beans good." [](https://expedia.ca/Farmington-Hotels-Comfort-Inn-Festus-St-Louis-South.h40138.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Festus - St. Louis South](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/6e70629c_y.jpg) ### La Quinta Inn & Suites by Wyndham Festus - St. Louis South 6/10 Okay "The room was just okay. Breakfast was decent if you want a waffle or snacks (only had water and coffee for drinks). They allowed some sketchy people to hang outside in the parking lot. I don’t even think they were guests, so we worried about leaving anything in the car. " [](https://expedia.ca/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information) ![Hampton Inn & Suites St. Louis/South I-55](https://images.trvl-media.com/lodging/4000000/3790000/3787100/3787094/cb2ee9ab_y.jpg) ### Hampton Inn & Suites St. Louis/South I-55 10/10 Excellent "We stay here all the time. Never had a problem from anything!" [](https://expedia.ca/St-Louis-Hotels-Hampton-Inn-Suites-StLouis-South-At-I-55.h3787094.Hotel-Information) ![The Principal Hotel](https://images.trvl-media.com/lodging/107000000/106860000/106856200/106856168/b212e706_y.jpg) ### The Principal Hotel 10/10 Excellent "Location is great.Beds were very comfortable." [](https://expedia.ca/Columbia-Hotels-The-Principal-Hotel.h106856168.Hotel-Information) ## Hotels near other Mercy Hospital Jefferson attractions ![Tranquil autumn landscape along the Osage River and Lake Ozarks in Missouri, United States](https://images.trvl-media.com/place/911402948989657088/da2e0baa-7d3b-41e2-bd97-504356e69714.jpg) ### Sunset Park After visiting Sunset Park, make a plan to see the other sights and activities in Festus. While in this family-friendly area, you can enjoy the restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911402948989657088) ![Flowering Red Bud tree, with purple buds, sidewalk, and historic black iron fence at Lafayette Park in St. Louis, Missouri.](https://images.trvl-media.com/place/911402538379870208/631685a1-7aba-4817-8bd2-518e6161a296.jpg) ### West City Park After visiting West City Park, make a plan to see the other sights and activities in Festus. While in this family-friendly area, you can enjoy the restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911402538379870208) ### Jorkerst Memorial Park After visiting Jorkerst Memorial Park, make a plan to see the other sights and activities in Festus. While in this family-friendly area, you can enjoy the restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911403959691083776) ### Lake Ladona Commune with nature and explore the great outdoors at Lake Ladona during your travels in Festus. While in this family-friendly area, you can enjoy the restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911401464604491776) ### Festus Public Library After visiting Festus Public Library, make a plan to see the other sights and activities in Festus. While in this family-friendly area, you can enjoy the restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911403170438422528) ### Crystal Park Crystal Park is just one of the places to see in Crystal City, so why not enjoy the other things to explore during your travels? Make some time to visit the churches while you're in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911404792881192960) ### Ogles Lake Commune with nature and explore the great outdoors at Ogles Lake during your travels in Festus. While in this family-friendly area, you can enjoy the restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911400282905464832) ### Williams Lake Commune with nature and explore the great outdoors at Williams Lake during your travels in Festus. While in this family-friendly area, you can enjoy the restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911400908492214272) ## Frequently asked questions ### What's the area like around Mercy Hospital Jefferson? ### What's the best hotel to stay close to Mercy Hospital Jefferson? ### How many hotels can I expect to find near Mercy Hospital Jefferson? ### If I need to cancel the hotel reservation for my stay near Mercy Hospital Jefferson, will I receive a refund?