Title: Book The Best Hotels in Melrose, FL for 2026 from CA $83 - Fully Refundable Options - Expedia.ca

[Vacation Rentals in Melrose](https://expedia.ca/Melrose-Vacation-Rentals.d3000431362.Travel-Guide-VacationRentals)[Melrose Car Rentals](https://expedia.ca/Car-Rentals-In-Melrose.d3000431362.Car-Rental-Guide)[Melrose Vacation Packages](https://expedia.ca/Melrose.d3000431362.Destination-Travel-Guides)

![Melrose, FL
Lake Santa Fe 
](https://images.trvl-media.com/place/3000431362/0b90ed1d-67eb-4497-a9f6-f9ac696978e8.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Matt Mateo

![](https://images.trvl-media.com/place/3000431362/0b90ed1d-67eb-4497-a9f6-f9ac696978e8.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Go beyond your typical stay in Melrose

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America&regionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-03-02&d1=2026-03-02&endDate=2026-03-04&d2=2026-03-04&travelerType=family_friendly)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America&regionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-03-02&d1=2026-03-02&endDate=2026-03-04&d2=2026-03-04&amenities=POOL)

Apart hotel

[](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America&regionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-03-02&d1=2026-03-02&endDate=2026-03-04&d2=2026-03-04&lodging=APART_HOTEL)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America&regionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-03-02&d1=2026-03-02&endDate=2026-03-04&d2=2026-03-04&amenities=HOT_TUB)

Cabin

[](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America&regionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-03-02&d1=2026-03-02&endDate=2026-03-04&d2=2026-03-04&lodging=CABIN)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America&regionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-03-02&d1=2026-03-02&endDate=2026-03-04&d2=2026-03-04&amenities=PETS)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America&regionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-03-02&d1=2026-03-02&endDate=2026-03-04&d2=2026-03-04&lodging=APARTMENT)

Cottage

[](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America&regionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-03-02&d1=2026-03-02&endDate=2026-03-04&d2=2026-03-04&lodging=COTTAGE)

Condo

[](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America&regionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-03-02&d1=2026-03-02&endDate=2026-03-04&d2=2026-03-04&lodging=CONDO)

## Check prices for these dates

Tonight

[Feb 16 - Feb 17](https://www.expedia.ca/Hotel-Search?regionId=3000431362&startDate=2026-02-16&endDate=2026-02-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 17 - Feb 18](https://www.expedia.ca/Hotel-Search?regionId=3000431362&startDate=2026-02-17&endDate=2026-02-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=3000431362&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=3000431362&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Melrose hotels

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/125000000/124180000/124177600/124177577/697ed988.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/125000000/124180000/124177600/124177577/07a081fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/125000000/124180000/124177600/124177577/f3e3dc51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/125000000/124180000/124177600/124177577/b4b21f2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hawthorne Angler's Cabin w/ Lake + Dock Access!

[](https://www.expedia.ca/Hawthorne-Hotels-Hawthorne-Anglers-Cabin-W-Lake-Dock-Access.h124177577.Hotel-Information)

Hawthorne

CA $233

CA $487 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Hawthorne-Hotels-Hawthorne-Anglers-Cabin-W-Lake-Dock-Access.h124177577.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/f683dfb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/e8a54c34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/3a3a359e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/44ce7551.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn & Suites Palatka Riverfront

[](https://www.expedia.ca/St-Augustine-Hotels-Quality-Inn-And-Suites-Riverfront.h7983.Hotel-Information)

Palatka

8.2/10

Very good

(1,002 reviews)

"Yes, great view, clean room, fabulous breakfast, helpful staff. Will use again"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Josephine

CA $126

CA $140 total

includes taxes & fees

Mar 8 - Mar 9

[](https://www.expedia.ca/St-Augustine-Hotels-Quality-Inn-And-Suites-Riverfront.h7983.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/087f9766.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only)](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/5e1b0ca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/aca6a7a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/51675133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Starke

[](https://www.expedia.ca/Gainesville-Hotels-Best-Western-Starke.h17274.Hotel-Information)

Starke

8.6/10

Excellent

(676 reviews)

"Quiet place, no issues checking in Or out."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cynthia

CA $135

CA $150 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Gainesville-Hotels-Best-Western-Starke.h17274.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/baab3408.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/eea1d68b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/098782ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/8ccd2f93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Starke by IHG

[](https://www.expedia.ca/Starke-Hotels-Holiday-Inn-Express-Starke.h90143200.Hotel-Information)

Starke

9.6/10

Exceptional

(483 reviews)

"Fantastic place! Staff is outstanding, the rooms are super clean, and breakfast is great. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kim

CA $146

CA $162 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Starke-Hotels-Holiday-Inn-Express-Starke.h90143200.Hotel-Information)

![Deluxe Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/22300/22209/e789f119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22300/22209/63d489bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/22300/22209/0eff6394.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/22300/22209/b035390e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Travelodge by Wyndham Gainesville

[](https://www.expedia.ca/Gainesville-Hotels-Regency-Inn.h22209.Hotel-Information)

Gainesville

7.0/10

Good

(177 reviews)

"We had good staying in this hotel, it is very comfortable and clean."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alexander

CA $75

CA $84 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Gainesville-Hotels-Regency-Inn.h22209.Hotel-Information)

![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2420000/2413900/2413834/3517b621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2420000/2413900/2413834/83cba0dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2420000/2413900/2413834/7e6ff378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2420000/2413900/2413834/9a502df8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Americas Best Value Inn Starke

[](https://www.expedia.ca/Gainesville-Hotels-Americas-Best-Value-Inn-Starke.h2413834.Hotel-Information)

Starke

7.4/10

Good

(545 reviews)

"Quiet, cozy, convenient and affordable "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kathryn

CA $87

CA $96 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Gainesville-Hotels-Americas-Best-Value-Inn-Starke.h2413834.Hotel-Information)

![Standard Double Room](https://images.trvl-media.com/lodging/124000000/123750000/123741900/123741815/ab06a2ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Single Room](https://images.trvl-media.com/lodging/124000000/123750000/123741900/123741815/f4ca4c49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/124000000/123750000/123741900/123741815/70c2cd09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/124000000/123750000/123741900/123741815/ebc25a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Soho Inn Waldo

[](https://www.expedia.ca/Waldo-Hotels-Soho-Inn-Waldo.h123741815.Hotel-Information)

Waldo

6.4/10

(7 reviews)

"Clean rooms ,checking in and out was a breeze,24 hour check in and on site Property manager.Simple Clean updated rooms with comfortable mattresses Great for a overnight stay or a weekend visit Rick the PM is a great guy and will ensure you are well situated "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Glenn

CA $95

CA $107 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Waldo-Hotels-Soho-Inn-Waldo.h123741815.Hotel-Information)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/910000/903300/903290/253a1423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/903300/903290/151eb783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/903300/903290/w851h683x1y0-6723da78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/910000/903300/903290/3b6e1844.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Red Carpet Inn

[](https://www.expedia.ca/Gainesville-Hotels-Red-Carpet-Inn.h903290.Hotel-Information)

Starke

8.6/10

Excellent

(628 reviews)

"Stayed here once before, would absolutely stay again. This hotel has excellent service and very clean, newly renovated rooms. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jessica

CA $89

CA $98 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Gainesville-Hotels-Red-Carpet-Inn.h903290.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/8a6fa57c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds, Non Smoking (Larger Room)](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/f246ff96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/4e0d3764.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/4d594d6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### HOM Hotel Gainesville, SureStay Collection by Best Western

[](https://www.expedia.ca/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information)

Gainesville

8.4/10

Very good

(1,824 reviews)

"Awesome place to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aristeo

CA $87

CA $98 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/920000/910300/910208/08745267.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/920000/910300/910208/155de35d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Non Smoking | Bathroom sink](https://images.trvl-media.com/lodging/1000000/920000/910300/910208/79c67c68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/920000/910300/910208/fc83fe5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Gator Town Inn

[](https://www.expedia.ca/Gainesville-Hotels-Gator-Town-Inn.h910208.Hotel-Information)

Gainesville

7.6/10

Good

(837 reviews)

"Can’t beat it for the price "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Drew

CA $79

CA $89 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Gainesville-Hotels-Gator-Town-Inn.h910208.Hotel-Information)

![Sports facility](https://images.trvl-media.com/lodging/16000000/15150000/15144900/15144895/188cda5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Minibar, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/16000000/15150000/15144900/15144895/376490ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/16000000/15150000/15144900/15144895/008ccc17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/16000000/15150000/15144900/15144895/45886083.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Palatka

[](https://www.expedia.ca/St-Augustine-Hotels-Hampton-Inn-Palatka.h15144895.Hotel-Information)

Palatka

9.2/10

Wonderful

(644 reviews)

"Our stay was excellent."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Noelia

CA $224

CA $249 total

includes taxes & fees

Feb 19 - Feb 20

[](https://www.expedia.ca/St-Augustine-Hotels-Hampton-Inn-Palatka.h15144895.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/c37dfd5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/5c4d5825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/1c3421f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/1210da70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Gainesville I-75 Hospital University Area

[](https://www.expedia.ca/Gainesville-Hotels-Super-8-By-Wyndham-Gainesville.h439799.Hotel-Information)

Gainesville

7.6/10

Good

(1,007 reviews)

"Good: Staff was very pleasant. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Marianna

CA $68

CA $77 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Gainesville-Hotels-Super-8-By-Wyndham-Gainesville.h439799.Hotel-Information)

![Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/894b95a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/5ca419d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/b54c320d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/9c79e172.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Waldo Inn and Suites

[](https://www.expedia.ca/Gainesville-Hotels-Best-Western-Waldo-Inn-And-Suites.h2384393.Hotel-Information)

Waldo

8.8/10

Excellent

(964 reviews)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cathy

CA $139

CA $156 total

includes taxes & fees

Feb 24 - Feb 25

[](https://www.expedia.ca/Gainesville-Hotels-Best-Western-Waldo-Inn-And-Suites.h2384393.Hotel-Information)

![Luxury Apartment, 2 Bedrooms, Lanai, Courtyard View | Private kitchen](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/02abb060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Studio, 1 Queen Bed, Kitchen, City View | Street view](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/72ee051a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Design Studio Suite, 1 Queen Bed, Patio, Courtyard Area | Bathroom](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/39089dc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/w997h664x0y3-a53eaa50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Depot Village

[](https://www.expedia.ca/Gainesville-Hotels-Depot-Village.h92535326.Hotel-Information)

Gainesville

9.6/10

Exceptional

(93 reviews)

"The cleanest room I have seen in years an amazing place to stay amazing people coffee shop on site perfect for a little getaway with downtown close by."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Megan

CA $48

CA $146 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/Gainesville-Hotels-Depot-Village.h92535326.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/0dff4e4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/57b6c63d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/19713bd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/93f8f773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Gainesville

[](https://www.expedia.ca/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information)

Gainesville

9.6/10

Exceptional

(1,384 reviews)

"Great place to stay. Would stay again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Leo

CA $143

CA $161 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/26000000/25010000/25007300/25007284/eace601f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/26000000/25010000/25007300/25007284/7a1f25d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Cabin, 2 Single Beds, Non Smoking](https://images.trvl-media.com/lodging/26000000/25010000/25007300/25007284/61f2cfbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Cabin, 2 Single Beds, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/26000000/25010000/25007300/25007284/edf12f39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Yearling Restaurant and Cabins

[](https://www.expedia.ca/Gainesville-Hotels-Yearling-Restaurant-And-Cabins.h25007284.Hotel-Information)

Hawthorne

9.2/10

Wonderful

(201 reviews)

"I stayed for one night and was happy with my cabin. It was clean and comfortable. The staff was friendly and welcoming, the check in process uncomplicated."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gabriele

CA $189

CA $213 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Gainesville-Hotels-Yearling-Restaurant-And-Cabins.h25007284.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/4000000/3080000/3071700/3071695/63174733.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3080000/3071700/3071695/11a97479.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3080000/3071700/3071695/a2aa59b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free buffet breakfast on weekdays](https://images.trvl-media.com/lodging/4000000/3080000/3071700/3071695/7e5fcb6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Palatka Northwest by IHG

[](https://www.expedia.ca/St-Augustine-Hotels-Holiday-Inn-Express-Palatka-Northwest.h3071695.Hotel-Information)

Palatka

9.2/10

Wonderful

(577 reviews)

"Good location, cleanroom, good breakfast."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nora

CA $219

CA $243 total

includes taxes & fees

Mar 15 - Mar 16

[](https://www.expedia.ca/St-Augustine-Hotels-Holiday-Inn-Express-Palatka-Northwest.h3071695.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/2000000/1640000/1631400/1631322/6e6778e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1640000/1631400/1631322/f7e7d47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1640000/1631400/1631322/fb54565b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1640000/1631400/1631322/7d49c4d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Gainesville

[](https://www.expedia.ca/Gainesville-Hotels-Hilton-Garden-Inn-Gainesville.h1631322.Hotel-Information)

Gainesville

8.8/10

Excellent

(1,008 reviews)

"Great stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Adriana

CA $116

CA $131 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Gainesville-Hotels-Hilton-Garden-Inn-Gainesville.h1631322.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/e387508a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/w2878h1920x0y0-ae7e9910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/9c03edaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/f5784012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Inn & Suites by Radisson, Gainesville, FL

[](https://www.expedia.ca/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information)

Gainesville

9.2/10

Wonderful

(1,685 reviews)

"Yes all very nice accommodations "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Louis

CA $120

CA $135 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/90000/82700/82677/5b4e3b0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/90000/82700/82677/0a8e44cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 King Bed, Accessible (Roll-In Shower, Smoke Free)](https://images.trvl-media.com/lodging/1000000/90000/82700/82677/16dba0bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Double Beds (2 Rooms, Smoke Free)](https://images.trvl-media.com/lodging/1000000/90000/82700/82677/89df9492.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Red Roof Inn PLUS+ Gainesville

[](https://www.expedia.ca/Gainesville-Hotels-Red-Roof-Inn-PLUS-Gainesville.h82677.Hotel-Information)

Gainesville

7.4/10

Good

(1,242 reviews)

"Would definitely stay there again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

William

CA $74

CA $83 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Gainesville-Hotels-Red-Roof-Inn-PLUS-Gainesville.h82677.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-02&endDate=2026-03-03&regionId=3000431362&adults=2&sort=RECOMMENDED&openPlayBack=true)

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## 

The Annual Vacation Sale 

Members save up to 40% on hotels and homes. Plan this year’s big trip and save. 

[Book now](https://expedia.ca/deals?rfrr=HTG_SPRING_PROMO_3000431362)

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[Sign in

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## Learn more about Melrose

Nestled along Lake Santa Fe, this charming town offers peaceful kayaking and fishing at Melrose Bay Park. Art lovers can browse local galleries and studios, then enjoy fresh farm-to-table dining at the weekend farmers' market.

[See all hotels in Melrose](https://www.expedia.ca/Hotel-Search?startDate=2026-03-02&endDate=2026-03-03&adults=2&regionId=3000431362)

![Melrose, FL
Lake Santa Fe 
](https://images.trvl-media.com/place/3000431362/0b90ed1d-67eb-4497-a9f6-f9ac696978e8.jpg?impolicy=fcrop&w=899&h=675&p=1&q=high)

Photo by Matt Mateo

## Top Melrose Hotel Reviews

![Drury Inn & Suites Gainesville](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/93f8f773_y.jpg)

### Drury Inn & Suites Gainesville

10/10 Excellent

"Clean rooms and courteous staff. Perfect location."

[](https://expedia.ca/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information)

![Sleep Inn & Suites University/Shands](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/3c8617a9_y.jpg)

### Sleep Inn & Suites University/Shands

10/10 Excellent

"Popcorn! They had fresh popcorn in the lobby. Quiet room. Good breakfast. Very friendly staff"

[](https://expedia.ca/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information)

![Hyatt Place Gainesville Downtown](https://images.trvl-media.com/lodging/79000000/78550000/78547700/78547624/894304b9_y.jpg)

### Hyatt Place Gainesville Downtown

10/10 Excellent

"Clean and modern. Staff attentive. "

[](https://expedia.ca/Gainesville-Hotels-Hyatt-Place-Gainesville-Downtown.h78547624.Hotel-Information)

![Comfort Inn University](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/78ca2e85_y.jpg)

### Comfort Inn University

10/10 Excellent

"The room while basic was comfortable and very clean. Just what we needed. We had a small glitch in extending our stay by one day but Barbara went above and beyond to fix the situation. She is one in a million and I can't thank her enough for her help."

[](https://expedia.ca/Gainesville-Hotels-Comfort-Inn-University.h793525.Hotel-Information)

![HOM Hotel Gainesville, SureStay Collection by Best Western](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/07c3ba53_y.jpg)

### HOM Hotel Gainesville, SureStay Collection by Best Western

10/10 Excellent

"No problem at all. Good breakfast and decent coffee."

[](https://expedia.ca/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information)

![Home2 Suites by Hilton Gainesville Medical Center](https://images.trvl-media.com/lodging/13000000/12790000/12786600/12786595/9c614776_y.jpg)

### Home2 Suites by Hilton Gainesville Medical Center

10/10 Excellent

"Perfect"

[](https://expedia.ca/Gainesville-Hotels-Home2-Suites-By-Hilton-Gainesville.h12786595.Hotel-Information)

![Hilton University of Florida Conference Center Gainesville](https://images.trvl-media.com/lodging/1000000/480000/475300/475205/7dbdcf15_y.jpg)

### Hilton University of Florida Conference Center Gainesville

10/10 Excellent

"The staff was very helpful specifically with help printing my boarding passes. The room was comfortable, and the entire vibe of the hotel was friendly. We will be staying there again on my next trip to Gainesville in May."

[](https://expedia.ca/Gainesville-Hotels-Hilton-University-Of-Florida-Conference-Center-Gainesville.h475205.Hotel-Information)

![Comfort Suites Gainesville near University](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/d62bb37b_y.jpg)

### Comfort Suites Gainesville near University

10/10 Excellent

"Friendly staff"

[](https://expedia.ca/Gainesville-Hotels-Comfort-Suites-Gainesville.h54138132.Hotel-Information)

![Country Inn & Suites by Radisson, Gainesville, FL](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/8584a629_y.jpg)

### Country Inn & Suites by Radisson, Gainesville, FL

10/10 Excellent

"Clean, quiet, reasonably priced."

[](https://expedia.ca/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information)

## More cheap stays in Melrose

![Red Roof Inn PLUS+ Gainesville](https://images.trvl-media.com/lodging/1000000/90000/82700/82677/5b4e3b0e_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Red Roof Inn PLUS+ Gainesville

3500 Southwest 42nd St Gainesville FL

CA $74

CA $83 total

Feb 17 - Feb 18

includes taxes & fees

7.2/10 Good! (1,249 reviews)

[](https://expedia.ca/Gainesville-Hotels-Red-Roof-Inn-PLUS-Gainesville.h82677.Hotel-Information)

![HOM Hotel Gainesville, SureStay Collection by Best Western](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/07c3ba53_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### HOM Hotel Gainesville, SureStay Collection by Best Western

3905 Sw 43Rd St Gainesville FL

CA $87

CA $98 total

Feb 17 - Feb 18

includes taxes & fees

8.4/10 Very Good! (1,823 reviews)

[](https://expedia.ca/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information)

![Sleep Inn & Suites University/Shands](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/3c8617a9_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Sleep Inn & Suites University/Shands

4110 SW 40th Boulevard Gainesville FL

CA $107

CA $128 total

Feb 22 - Feb 23

includes taxes & fees

8.6/10 Excellent! (1,101 reviews)

[](https://expedia.ca/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information)

![Comfort Inn University](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/78ca2e85_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Comfort Inn University

3440 SW 40th Blvd Gainesville FL

CA $110

CA $131 total

Feb 22 - Feb 23

includes taxes & fees

8.2/10 Very Good! (1,028 reviews)

[](https://expedia.ca/Gainesville-Hotels-Comfort-Inn-University.h793525.Hotel-Information)

![Quality Inn & Suites Palatka Riverfront](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/eb8d0761_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Quality Inn & Suites Palatka Riverfront

201 N 1st Street Palatka FL

CA $126

CA $140 total

Mar 8 - Mar 9

includes taxes & fees

8.2/10 Very Good! (1,000 reviews)

[](https://expedia.ca/St-Augustine-Hotels-Quality-Inn-And-Suites-Riverfront.h7983.Hotel-Information)

![Comfort Suites Gainesville near University](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/d62bb37b_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Comfort Suites Gainesville near University

2603 SW 13TH STREET Gainesville FL

CA $142

CA $160 total

Feb 22 - Feb 23

includes taxes & fees

9/10 Wonderful! (1,227 reviews)

[](https://expedia.ca/Gainesville-Hotels-Comfort-Suites-Gainesville.h54138132.Hotel-Information)

## Hotels in Melrose with star rating

![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg)

4 Star Hotels

5 properties

[](https://expedia.ca/4Star-Melrose-Hotels.s40-0-d3000431362.Travel-Guide-Filter-Hotels)

![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg)

3 Star Hotels

77 properties

[](https://expedia.ca/3Star-Melrose-Hotels.s30-0-d3000431362.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

123 properties

[](https://expedia.ca/2Star-Melrose-Hotels.s20-0-d3000431362.Travel-Guide-Filter-Hotels)

## Frequently asked questions

### What is the best area to stay in Melrose?

> This area provides direct access to the lake, which is the heart of Melrose's recreational activities. Properties here often feature private docks, offering convenience for those who enjoy boating, fishing, or simply relaxing by the water. The main roads like State Road 21 run nearby, providing easy access to local shops and eateries while still maintaining a peaceful, residential feel.
> 
>   
> Families often find this area ideal due to the focus on outdoor activities. Children can enjoy swimming, kayaking, or paddleboarding directly from their accommodation, and the open spaces around the lake are great for playing. The proximity to nature trails also offers opportunities for family walks and exploring the local wildlife.
> 
>   
> Couples looking for a peaceful retreat will appreciate the quiet surroundings and scenic views of the lake. Many accommodations in this area offer private settings, great for romantic evenings watching the sunset over the water or enjoying a quiet morning coffee on a lakeside porch.

### When is the best time to go to Melrose?

> During these periods, the weather is pleasantly warm with lower humidity, making it ideal for enjoying outdoor activities. Average temperatures range from 20-28°C (68-82°F), great for exploring the natural beauty of the area, like kayaking on Lake Santa Fe or hiking in the nearby state parks. These seasons also avoid the peak summer heat and the higher risk of hurricanes.
> 
>   
> Couples looking for a peaceful escape will appreciate the quieter atmosphere during these shoulder seasons. You can enjoy strolls through the small town centre, visit local antique shops, or have a relaxed meal at one of the lakeside restaurants without the larger crowds of peak tourist times.
> 
>   
> Families will find these times suitable for outdoor adventures. The comfortable temperatures mean children can comfortably explore the parks and enjoy water activities without the intensity of summer heat.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Melrose hotel booking with Expedia?

### How much is the nightly rate at a Melrose hotel?

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