Title: Book The Best Hotels in Melrose, FL for 2026 from CA $92 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Melrose](https://expedia.ca/Melrose-Vacation-Rentals.d3000431362.Travel-Guide-VacationRentals)[Melrose Car Rentals](https://expedia.ca/Car-Rentals-In-Melrose.d3000431362.Car-Rental-Guide)[Melrose Vacation Packages](https://expedia.ca/Melrose.d3000431362.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/3000431362/0b90ed1d-67eb-4497-a9f6-f9ac696978e8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Matt Mateo ![](https://images.trvl-media.com/place/3000431362/0b90ed1d-67eb-4497-a9f6-f9ac696978e8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Melrose Pool [](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-19&d2=2026-04-19&amenities=POOL) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-19&d2=2026-04-19&travelerType=family_friendly) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-19&d2=2026-04-19&amenities=PETS) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-19&d2=2026-04-19&amenities=HOT_TUB) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-19&d2=2026-04-19&lodging=APARTMENT) Cabin [](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-19&d2=2026-04-19&lodging=CABIN) Condo [](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-19&d2=2026-04-19&lodging=CONDO) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Melrose%2C+Florida%2C+United+States+of+America®ionId=3000431362&latLong=29.70941%2C-82.04982&adults=2&startDate=2026-04-17&d1=2026-04-17&endDate=2026-04-19&d2=2026-04-19&lodging=COTTAGE) ## Check prices for these dates Tonight [Apr 3 - Apr 4](https://www.expedia.ca/Hotel-Search?regionId=3000431362&startDate=2026-04-03&endDate=2026-04-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 4 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=3000431362&startDate=2026-04-04&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=3000431362&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=3000431362&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Melrose hotels ![Luxury Apartment, 2 Bedrooms, Lanai, Courtyard View | Private kitchen](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/02abb060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Studio, 1 Queen Bed, Kitchen, City View | Living area](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/e1175056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Studio Suite, 1 Queen Bed, Patio, Courtyard Area | Bathroom](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/39089dc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/w997h664x0y3-a53eaa50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Depot Village [](https://www.expedia.ca/Gainesville-Hotels-Depot-Village.h92535326.Hotel-Information) Gainesville 9.6/10 Exceptional (111 reviews) "My fav spot to stay in town 💚" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda CA $46 CA $145 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Gainesville-Hotels-Depot-Village.h92535326.Hotel-Information) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/125000000/124180000/124177600/124177577/697ed988.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/125000000/124180000/124177600/124177577/f3e3dc51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/125000000/124180000/124177600/124177577/07a081fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/125000000/124180000/124177600/124177577/b4b21f2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hawthorne Angler's Cabin w/ Lake + Dock Access! [](https://www.expedia.ca/Hawthorne-Hotels-Hawthorne-Anglers-Cabin-W-Lake-Dock-Access.h124177577.Hotel-Information) Hawthorne CA $229 CA $487 total includes taxes & fees Apr 11 - Apr 12 [](https://www.expedia.ca/Hawthorne-Hotels-Hawthorne-Anglers-Cabin-W-Lake-Dock-Access.h124177577.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/f683dfb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/eb8d0761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/44ce7551.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/e8a54c34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Palatka Riverfront [](https://www.expedia.ca/St-Augustine-Hotels-Quality-Inn-And-Suites-Riverfront.h7983.Hotel-Information) Palatka 8.2/10 Very good (1,000 reviews) "Great room and good breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janae CA $143 CA $159 total includes taxes & fees Apr 14 - Apr 15 [](https://www.expedia.ca/St-Augustine-Hotels-Quality-Inn-And-Suites-Riverfront.h7983.Hotel-Information) ![Deluxe Double Room](https://images.trvl-media.com/lodging/10000000/9730000/9724900/9724836/63544d46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/10000000/9730000/9724900/9724836/5f96d719.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Single Room, 1 King Bed](https://images.trvl-media.com/lodging/10000000/9730000/9724900/9724836/77400e0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9730000/9724900/9724836/cc24bcdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gainesville Lodge [](https://www.expedia.ca/Gainesville-Hotels-Gainesville-Lodge.h9724836.Hotel-Information) Gainesville 7.4/10 Good (10 reviews) "Thank for a great stay. So much better than the usual corporate hotels. Staff were very helpful. Room was very nice." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Maxwell John CA $117 CA $132 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Gainesville-Hotels-Gainesville-Lodge.h9724836.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/920000/910300/910208/08745267.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/920000/910300/910208/155de35d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Double Bed, Non Smoking | Television](https://images.trvl-media.com/lodging/1000000/920000/910300/910208/cc36dca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Bathroom sink](https://images.trvl-media.com/lodging/1000000/920000/910300/910208/79c67c68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gator Town Inn [](https://www.expedia.ca/Gainesville-Hotels-Gator-Town-Inn.h910208.Hotel-Information) Gainesville 7.6/10 Good (860 reviews) "The room was clean and the beds were comfortable. For the quality price, I would recommend this hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $82 CA $92 total includes taxes & fees May 4 - May 5 [](https://www.expedia.ca/Gainesville-Hotels-Gator-Town-Inn.h910208.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/26000000/25010000/25007300/25007284/eace601f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cabin, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/26000000/25010000/25007300/25007284/da811b1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cabin, 2 Single Beds, Non Smoking](https://images.trvl-media.com/lodging/26000000/25010000/25007300/25007284/61f2cfbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cabin, 2 Single Beds, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/26000000/25010000/25007300/25007284/edf12f39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yearling Restaurant and Cabins [](https://www.expedia.ca/Gainesville-Hotels-Yearling-Restaurant-And-Cabins.h25007284.Hotel-Information) Hawthorne 9.2/10 Wonderful (206 reviews) "The Yearling Cabins are somewhat remote. I planned my stay around a guided tour at the Marjorie Kinnan Rawlings State park and dining at the Yearling Restaurant." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarah CA $193 CA $217 total includes taxes & fees Apr 18 - Apr 19 [](https://www.expedia.ca/Gainesville-Hotels-Yearling-Restaurant-And-Cabins.h25007284.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/910000/903300/903290/253a1423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/903300/903290/151eb783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/903300/903290/9640a44e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/903300/903290/3b6e1844.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Carpet Inn [](https://www.expedia.ca/Gainesville-Hotels-Red-Carpet-Inn.h903290.Hotel-Information) Starke 8.6/10 Excellent (640 reviews) "Clean, inexpensive with a courteous staff. Will stay there again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $96 CA $107 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Gainesville-Hotels-Red-Carpet-Inn.h903290.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/087f9766.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only)](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/5e1b0ca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/aca6a7a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17300/17274/51675133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Starke [](https://www.expedia.ca/Gainesville-Hotels-Best-Western-Starke.h17274.Hotel-Information) Starke 8.6/10 Excellent (695 reviews) "Very pleasant and helpful staff, clean quiet, comfortable room, easy room access to handicapped room from parking. Good proximity to restaurants and shopping." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marie CA $149 CA $165 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Gainesville-Hotels-Best-Western-Starke.h17274.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/8a6fa57c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/4d594d6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/2f0849f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking (Larger Room)](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/f246ff96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOM Hotel Gainesville, SureStay Collection by Best Western [](https://www.expedia.ca/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information) Gainesville 8.4/10 Very good (1,864 reviews) "Overall a great stay ! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angi CA $107 CA $121 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/7000000/6660000/6655300/6655254/8969646a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/7000000/6660000/6655300/6655254/264fb72f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/7000000/6660000/6655300/6655254/af8a5e8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6660000/6655300/6655254/282217f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crystal Cove Hotel [](https://www.expedia.ca/St-Augustine-Hotels-Crystal-Cove-Hotel.h6655254.Hotel-Information) Palatka 7.4/10 Good (705 reviews) "Just a nice comfortable spot to stay in nice and quiet all around good place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $123 CA $136 total includes taxes & fees Apr 10 - Apr 11 [](https://www.expedia.ca/St-Augustine-Hotels-Crystal-Cove-Hotel.h6655254.Hotel-Information) ![Deluxe Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/22300/22209/e789f119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22300/22209/63d489bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/22300/22209/b035390e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/22300/22209/0eff6394.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Gainesville [](https://www.expedia.ca/Gainesville-Hotels-Regency-Inn.h22209.Hotel-Information) Gainesville 7.2/10 Good (198 reviews) "We had good staying in this hotel, it is very comfortable and clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexander CA $82 CA $92 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Gainesville-Hotels-Regency-Inn.h22209.Hotel-Information) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98549900/98549817/6285009b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98549900/98549817/633fad00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98549900/98549817/ee947295.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/99000000/98550000/98549900/98549817/b390c59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3 Mi to UF: Townhome w/ Patio in Gainesville! [](https://www.expedia.ca/Gainesville-Hotels-Gainesville-Townhome-Vacation-Rental-3-Mi-To-UF.h98549817.Hotel-Information) Gainesville CA $129 CA $422 total includes taxes & fees Apr 9 - Apr 10 [](https://www.expedia.ca/Gainesville-Hotels-Gainesville-Townhome-Vacation-Rental-3-Mi-To-UF.h98549817.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/0dff4e4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/57b6c63d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/19713bd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/93f8f773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Gainesville [](https://www.expedia.ca/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information) Gainesville 9.6/10 Exceptional (1,413 reviews) "Great place to stay! Would recommend. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $157 CA $177 total includes taxes & fees Apr 21 - Apr 22 [](https://www.expedia.ca/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/537800/537785/296e0837.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/540000/537800/537785/577d50e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/540000/537800/537785/d2f8f8b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/540000/537800/537785/dccaee1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Gainesville I-75 [](https://www.expedia.ca/Gainesville-Hotels-Quality-Inn-Gainesville-I-75.h537785.Hotel-Information) Gainesville 7.6/10 Good (942 reviews) "The room was lovely and the bedding was very cozy." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra CA $106 CA $120 total includes taxes & fees Apr 14 - Apr 15 [](https://www.expedia.ca/Gainesville-Hotels-Quality-Inn-Gainesville-I-75.h537785.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/baab3408.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/8ccd2f93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/098782ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/eea1d68b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Starke by IHG [](https://www.expedia.ca/Starke-Hotels-Holiday-Inn-Express-Starke.h90143200.Hotel-Information) Starke 9.6/10 Exceptional (517 reviews) "Facility was very clean and breakfast was very good. Would definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sheila CA $164 CA $182 total includes taxes & fees Apr 19 - Apr 20 [](https://www.expedia.ca/Starke-Hotels-Holiday-Inn-Express-Starke.h90143200.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/e387508a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/w2878h1920x0y0-ae7e9910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/f5784012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/9c03edaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Gainesville, FL [](https://www.expedia.ca/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information) Gainesville 9.2/10 Wonderful (1,741 reviews) "Great hotel to stay!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew S. Higgins CA $123 CA $139 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information) ![Desk, iron/ironing board, free cribs/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/70ccd44a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/d8c6de93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/cba0289f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/f7f29b03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites University/Shands [](https://www.expedia.ca/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) Gainesville 8.8/10 Excellent (1,156 reviews) "Breakfast was good , staff was friendly, parking was always available, the room was spacious and clean ." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $118 CA $140 total includes taxes & fees Apr 7 - Apr 8 [](https://www.expedia.ca/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/a1a33286.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/b54c320d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/5ca419d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/894b95a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Waldo Inn and Suites [](https://www.expedia.ca/Gainesville-Hotels-Best-Western-Waldo-Inn-And-Suites.h2384393.Hotel-Information) Waldo 8.8/10 Excellent (982 reviews) "Was good … Breakfast was suprising good .. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bill CA $142 CA $160 total includes taxes & fees Apr 14 - Apr 15 [](https://www.expedia.ca/Gainesville-Hotels-Best-Western-Waldo-Inn-And-Suites.h2384393.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1201500/1201421/c2f8fb6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/2000000/1210000/1201500/1201421/80ba97e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/2000000/1210000/1201500/1201421/b7bef0c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1210000/1201500/1201421/b36d5429.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sweetwater Branch Inn [](https://www.expedia.ca/Gainesville-Hotels-Sweetwater-Branch-Inn.h1201421.Hotel-Information) Gainesville 9.6/10 Exceptional (1,000 reviews) "I loved this place! It was a perfect location and charming vibe. The breakfast was amazing." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jaramee CA $134 CA $151 total includes taxes & fees Apr 26 - Apr 27 [](https://www.expedia.ca/Gainesville-Hotels-Sweetwater-Branch-Inn.h1201421.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2420000/2413900/2413834/3517b621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/3000000/2420000/2413900/2413834/ad551cb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2420000/2413900/2413834/83cba0dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2420000/2413900/2413834/7e6ff378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Starke [](https://www.expedia.ca/Gainesville-Hotels-Americas-Best-Value-Inn-Starke.h2413834.Hotel-Information) Starke 7.4/10 Good (553 reviews) "Quiet, cozy, convenient and affordable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathryn CA $118 CA $131 total includes taxes & fees Apr 21 - Apr 22 [](https://www.expedia.ca/Gainesville-Hotels-Americas-Best-Value-Inn-Starke.h2413834.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-17&endDate=2026-04-18®ionId=3000431362&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMelrose-Hotels.d3000431362.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMelrose-Hotels.d3000431362.Travel-Guide-Hotels) ## Learn more about Melrose Nestled along Lake Santa Fe, this charming town offers peaceful kayaking and fishing at Melrose Bay Park. Art lovers can browse local galleries and studios, then enjoy fresh farm-to-table dining at the weekend farmers' market. [See all hotels in Melrose](https://www.expedia.ca/Hotel-Search?startDate=2026-04-17&endDate=2026-04-18&adults=2®ionId=3000431362) ![](https://images.trvl-media.com/place/3000431362/0b90ed1d-67eb-4497-a9f6-f9ac696978e8.jpg?impolicy=fcrop&w=899&h=675&p=1&q=high) Photo by Matt Mateo ## Top Melrose Hotel Reviews ## Recent Reviews in Melrose ![Hotel Indigo Gainesville-Celebration Pointe by IHG](https://images.trvl-media.com/lodging/27000000/26950000/26940800/26940780/dfb2f417_y.jpg) ### Hotel Indigo Gainesville-Celebration Pointe by IHG 6/10 Okay "No Coffee available after " [](https://expedia.ca/Gainesville-Hotels-Hotel-Indigo-Gainesville-Celebration-Pointe.h26940780.Hotel-Information) ![Hyatt Place Gainesville Downtown](https://images.trvl-media.com/lodging/79000000/78550000/78547700/78547624/0d00e88d_y.jpg) ### Hyatt Place Gainesville Downtown 8/10 Good "Hotel was great, good breakfast. Parking situation is aggravating as there is no hotel parking. I can see that in busy times that could be a huge problem. Otherwise everything was good." [](https://expedia.ca/Gainesville-Hotels-Hyatt-Place-Gainesville-Downtown.h78547624.Hotel-Information) ![Country Inn & Suites by Radisson, Gainesville, FL](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/e387508a_y.jpg) ### Country Inn & Suites by Radisson, Gainesville, FL 10/10 Excellent "We had a great overnight family of 4 stay. The breakfast buffet was surprisingly very good! The beds as well as the pillows were very comfortable. The only negative was the bathroom sink drained a little slow so I only gave it four stars under the cleanliness rating." [](https://expedia.ca/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information) ![Travelodge by Wyndham Gainesville](https://images.trvl-media.com/lodging/1000000/30000/22300/22209/e789f119_y.jpg) ### Travelodge by Wyndham Gainesville 6/10 Okay "Saying I had to pay an additional deposit for a room I already paid for" [](https://expedia.ca/Gainesville-Hotels-Regency-Inn.h22209.Hotel-Information) ![Quality Inn Gainesville near University](https://images.trvl-media.com/lodging/1000000/10000/1300/1220/a7376ef0_y.jpg) ### Quality Inn Gainesville near University 10/10 Excellent "None " [](https://expedia.ca/Gainesville-Hotels-Quality-Inn-University.h1220.Hotel-Information) ![Hilton University of Florida Conference Center Gainesville](https://images.trvl-media.com/lodging/1000000/480000/475300/475205/50a7bef2_y.jpg) ### Hilton University of Florida Conference Center Gainesville 10/10 Excellent "The bed was cozy, the pillows were great. The room was quiet, and the air conditioner kept the room cool." [](https://expedia.ca/Gainesville-Hotels-Hilton-University-Of-Florida-Conference-Center-Gainesville.h475205.Hotel-Information) ![Drury Inn & Suites Gainesville](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/0dff4e4a_y.jpg) ### Drury Inn & Suites Gainesville 10/10 Excellent "Clean and friendly environment " [](https://expedia.ca/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information) ![Sleep Inn & Suites University/Shands](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/70ccd44a_y.jpg) ### Sleep Inn & Suites University/Shands 8/10 Good "The breakfast was very good, but the woman that was in the breakfast room arranging the food was extremely rude. She treated my 80 year old mother very bad. I complained to the front desk and they said many people have complained about her. I don't understand why the manager does not do anything about it. " [](https://expedia.ca/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) ![Comfort Suites Gainesville near University](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/95cd6e6a_y.jpg) ### Comfort Suites Gainesville near University 6/10 Okay "Asked to clean the room the day before and day of to three different people including the general manager. Room wasn’t cleaned. Tease you about Otis Spunkenmeyer cookies but never gave it. Get rid of the oven. Breakfast items run out and they don’t replenish." [](https://expedia.ca/Gainesville-Hotels-Comfort-Suites-Gainesville.h54138132.Hotel-Information) ## More cheap stays in Melrose ![Red Roof Inn PLUS+ Gainesville](https://images.trvl-media.com/lodging/1000000/90000/82700/82677/5b4e3b0e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Red Roof Inn PLUS+ Gainesville 3500 Southwest 42nd St Gainesville FL CA $88 CA $99 total Apr 8 - Apr 9 includes taxes & fees 7.4/10 Good! (1,253 reviews) [](https://expedia.ca/Gainesville-Hotels-Red-Roof-Inn-PLUS-Gainesville.h82677.Hotel-Information) ![HOM Hotel Gainesville, SureStay Collection by Best Western](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/8a6fa57c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOM Hotel Gainesville, SureStay Collection by Best Western 3905 Sw 43Rd St Gainesville FL CA $107 CA $121 total Apr 12 - Apr 13 includes taxes & fees 8.4/10 Very Good! (1,864 reviews) [](https://expedia.ca/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information) ![Quality Inn Gainesville near University](https://images.trvl-media.com/lodging/1000000/10000/1300/1220/a7376ef0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Gainesville near University 2435 Sw 13th Street Gainesville FL CA $106 CA $124 total Apr 19 - Apr 20 includes taxes & fees 7/10 Good! (1,001 reviews) [](https://expedia.ca/Gainesville-Hotels-Quality-Inn-University.h1220.Hotel-Information) ![Sleep Inn & Suites University/Shands](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/70ccd44a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sleep Inn & Suites University/Shands 4110 SW 40th Boulevard Gainesville FL CA $118 CA $140 total Apr 7 - Apr 8 includes taxes & fees 8.8/10 Excellent! (1,156 reviews) [](https://expedia.ca/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) ![Comfort Suites Gainesville near University](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/95cd6e6a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Suites Gainesville near University 2603 SW 13TH STREET Gainesville FL CA $136 CA $153 total Apr 20 - Apr 21 includes taxes & fees 9.2/10 Wonderful! (1,286 reviews) [](https://expedia.ca/Gainesville-Hotels-Comfort-Suites-Gainesville.h54138132.Hotel-Information) ![Quality Inn & Suites Palatka Riverfront](https://images.trvl-media.com/lodging/1000000/10000/8000/7983/f683dfb7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn & Suites Palatka Riverfront 201 N 1st Street Palatka FL CA $143 CA $159 total Apr 14 - Apr 15 includes taxes & fees 8.2/10 Very Good! (1,000 reviews) [](https://expedia.ca/St-Augustine-Hotels-Quality-Inn-And-Suites-Riverfront.h7983.Hotel-Information) ## Hotels in Melrose with star rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 5 properties [](https://expedia.ca/4Star-Melrose-Hotels.s40-0-d3000431362.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 82 properties [](https://expedia.ca/3Star-Melrose-Hotels.s30-0-d3000431362.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 46 properties [](https://expedia.ca/2Star-Melrose-Hotels.s20-0-d3000431362.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### What is the best area to stay in Melrose? > This area provides direct access to the lake, which is the heart of Melrose's recreational activities. Properties here often feature private docks, offering convenience for those who enjoy boating, fishing, or simply relaxing by the water. The main roads like State Road 21 run nearby, providing easy access to local shops and eateries while still maintaining a peaceful, residential feel. > > > Families often find this area ideal due to the focus on outdoor activities. Children can enjoy swimming, kayaking, or paddleboarding directly from their accommodation, and the open spaces around the lake are great for playing. The proximity to nature trails also offers opportunities for family walks and exploring the local wildlife. > > > Couples looking for a peaceful retreat will appreciate the quiet surroundings and scenic views of the lake. Many accommodations in this area offer private settings, great for romantic evenings watching the sunset over the water or enjoying a quiet morning coffee on a lakeside porch. ### When is the best time to go to Melrose? > During these periods, the weather is pleasantly warm with lower humidity, making it ideal for enjoying outdoor activities. Average temperatures range from 20-28°C (68-82°F), great for exploring the natural beauty of the area, like kayaking on Lake Santa Fe or hiking in the nearby state parks. These seasons also avoid the peak summer heat and the higher risk of hurricanes. > > > Couples looking for a peaceful escape will appreciate the quieter atmosphere during these shoulder seasons. You can enjoy strolls through the small town centre, visit local antique shops, or have a relaxed meal at one of the lakeside restaurants without the larger crowds of peak tourist times. > > > Families will find these times suitable for outdoor adventures. The comfortable temperatures mean children can comfortably explore the parks and enjoy water activities without the intensity of summer heat. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Melrose hotel booking with Expedia? ### How much is the nightly rate at a Melrose hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [3 Star Hotels in Grandin ](https://www.expedia.ca/3Star-Grandin-Hotels.s30-0-d553248635975871409.Travel-Guide-Filter-Hotels) - [Hotels near Ben Hill Griffin Stadium ](https://www.expedia.ca/Ben-Hill-Griffin-Stadium-Hotels.0-l6068633-0.Travel-Guide-Filter-Hotels) - [Brooker Hotels ](https://www.expedia.ca/Brooker-Hotels.d6352173.Travel-Guide-Hotels) - [Citra Hotels ](https://www.expedia.ca/Citra-Hotels.d6317344.Travel-Guide-Hotels) - [Cross Creek Hotels ](https://www.expedia.ca/Cross-Creek-Hotels.d553248635975848431.Travel-Guide-Hotels) - [Alachua County Hotels ](https://www.expedia.ca/Destinations-In-Alachua-County.d553248635976432190.Hotel-Destinations) - 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