A waterfront with Spanish moss-covered trees, a wooden dock, and a distant shoreline.

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Our top choices for Melrose hotels

A swimming pool with a metal ladder, surrounded by a white fence and green chairs.
A refrigerated display case with beverages and snacks, and a shelf with bottled water and other beverages.
A living room with a curved sofa, a wooden cabinet, and a fish tank.
A hotel room with a bed, a sofa, a coffee table, and a small table with a lamp.

1. Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
Waldo
United States
Ana Laura
CA $133
CA $150 total
includes taxes & fees
Oct 11 - Oct 12
Best Western Waldo Inn and Suites
A modern breakfast area with labeled dispensers for yogurt, eggs, and milk, a coffee machine, and a chalkboard menu.
A modern reception desk area with a blue geometric wall design, wooden accents, and a visible reception counter.
An outdoor patio with tables and chairs, a stone wall, and a view of a street with trees and buildings.
A hotel room with two beds, a TV, a desk, and a chair.

2. Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
Starke
United States
Judy
CA $157
CA $174 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Express Starke by IHG
A room with two beds, a TV, and a door.
A bathroom with a toilet, sink, and mirror.
A covered corridor with a row of parked cars on one side and a building with blue trim on the other.
A hotel room with a bed, a TV mounted on the wall, a remote control on a table, and a door leading to another room.

3. Soho Inn Waldo

Soho Inn Waldo
Waldo
United States
Keith
CA $77
CA $87 total
includes taxes & fees
Oct 5 - Oct 6
Soho Inn Waldo
A modern interior with a staircase, a seating area, and a colorful abstract wall design.
A rooftop pool area with lounge chairs, a small table, and a fire pit.
A spacious lobby with modern furniture, large windows, and a colorful abstract wall.
A modern hotel lobby with a round table featuring two drinks, a sofa, and a colorful wall art piece.

4. Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown
Downtown Gainesville
United States
Claire
CA $140
CA $157 total
includes taxes & fees
Oct 11 - Oct 12
Hyatt Place Gainesville Downtown
A modern living room with a fireplace, comfortable seating, a flat-screen TV, and a large window.
A modern hotel lobby with a long dining table, multiple seating areas, and a large window with curtains.
A modern hotel lobby with a reception desk, seating area with chairs and ottomans, a large artwork, and a corridor leading to other rooms.
A hotel room with a bed, a desk, a chair, a sofa, and a window.

5. Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
Gainesville
United States
thomas
CA $118
CA $137 total
includes taxes & fees
Oct 11 - Oct 12
Comfort Suites Gainesville near University
A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.
A modern kitchen with wooden cabinets, a granite countertop, and pendant lighting.
A hotel lobby with a stone wall, a flat-screen TV, orange upholstered seating, and a lamp.
A hotel room with two beds, a large headboard, bedside lamps, and a view of the outdoors through sheer curtains.

6. Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
Gainesville
United States
Adam
CA $150
CA $168 total
includes taxes & fees
Oct 11 - Oct 12
Drury Inn & Suites Gainesville
A kitchen with a sink, a microwave, and cabinets.
A bedroom with a bed, curtains, a painting, and a lamp.
A room with a patterned sofa, a green door with a decorative glass panel, and a framed picture on the wall.
A small building with a yellow door, surrounded by trees and parked cars.

7. The Humming Bird Suite - Affordable Lakefront Fun

The Humming Bird Suite - Affordable Lakefront Fun
Keystone Heights
CA $114
CA $175 total
includes taxes & fees
Oct 5 - Oct 6
The Humming Bird Suite - Affordable Lakefront Fun
A large, two-story house with a porch, multiple windows, and a chimney.
A garden with a stone fountain, a gazebo, and a winding brick path.
A grand staircase with ornate carpet, a cozy sitting area with a sofa and chairs, and a large window with a view.
A cozy living room with a Christmas tree, a fireplace with stockings, and a view through a window.

8. Sweetwater Branch Inn

Sweetwater Branch Inn
Gainesville
United States
Jose
CA $161
CA $182 total
includes taxes & fees
Oct 6 - Oct 7
Sweetwater Branch Inn
A multi-story hotel with a central entrance, palm trees, and a clear sky.
A spacious hotel lobby with a modern staircase, a seating area with a sofa and chairs, and a dining area in the background.
A hotel room with a wooden floor, a red armchair, a beige sofa, a TV, and framed artwork on the wall.
A modern living room with a green sofa, a round coffee table, and a fireplace.

9. Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
Gainesville
United States
sherry
CA $126
CA $142 total
includes taxes & fees
Oct 12 - Oct 13
Country Inn & Suites by Radisson, Gainesville, FL
A hotel room with a bed, two bedside tables with lamps, a large bathtub, and green walls.
A Sleep Inn & Suites building with a clear entrance, a covered waiting area, and a parking lot.
A hotel room with two beige armchairs, a small side table, a glass display cabinet with sports memorabilia, a mounted flat-screen TV, and a door with a wooden frame.
Outdoor lounge chairs with metal frames and fabric seats, arranged in rows.

10. Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
Gainesville
United States
prakasa Babu
CA $108
CA $129 total
includes taxes & fees
Oct 26 - Oct 27
Sleep Inn & Suites University/Shands
A gazebo with a tiled roof, surrounded by stone pillars and palm trees.
A modern hotel room with a large bed, bedside tables, a desk, and a mirror.
A reception area with a modern design, featuring a reception desk, a blue patterned wall, and a glass door leading outside.
A modern restaurant with a blue wave-patterned wall, a self-service beverage station, and a variety of food items displayed.

11. Best Western Starke

Best Western Starke
Starke
United States
Christopher
CA $148
CA $165 total
includes taxes & fees
Oct 5 - Oct 6
Best Western Starke
A hotel lobby with a seating area, a sofa, a table, and a lamp.
A multi-story hotel with a brick facade, a prominent signage for Hampton Inn & Suites, and a parking area with several cars.
A hotel lobby with multiple seating areas, including tables and booths, a coffee station, and a reception desk.
A snack and treat display area with refrigerated sections and shelves stocked with various snacks.

12. Hampton Inn & Suites Gainesville Downtown University

Hampton Inn & Suites Gainesville Downtown University
Downtown Gainesville
United States
Graziella
CA $133
CA $150 total
includes taxes & fees
Oct 11 - Oct 12
Hampton Inn & Suites Gainesville Downtown University
A swimming pool with lounge chairs and a gazebo, surrounded by palm trees and a building with a stone facade.
A coffee station with two coffee machines, a sign above stating "MUST HAVE COFFEE EXPRESS", and various coffee-related items on shelves.
A reception desk with a computer, a framed picture, and a sign indicating a storage room.
A coffee station with two coffee machines, a coffee press, and various coffee pods and cups.

13. Holiday Inn Express & Suites Gainesville I-75 by IHG

Holiday Inn Express & Suites Gainesville I-75 by IHG
Gainesville
United States
Meredith
CA $152
CA $172 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express & Suites Gainesville I-75 by IHG
A clear blue swimming pool with a metal safety fence, surrounded by a building with multiple windows and balconies.
A hotel room with two beds, each with a patterned bedspread. There are two wall-mounted lamps on the nightstand between the beds.
A hotel room with a wooden headboard, a colorful striped bedspread, two bedside lamps, a framed picture on the wall, and a small bedside table with a phone.
A single-story motel with a red roof and beige walls. It features a covered front porch and a small parking area.

14. Red Carpet Inn

Red Carpet Inn
Starke
United States
Mark
CA $98
CA $109 total
includes taxes & fees
Oct 5 - Oct 6
Red Carpet Inn
A modern hotel lobby with a curved ceiling, a central seating area with a sofa and ottoman, a bar area, and a dining space with chairs and tables.
A hotel entrance with a sign reading "Springhill Suites by Marriott" and a modern building in the background.
A spacious lobby with a modern design, featuring a large seating area with sofas and chairs, a patterned carpet, and large windows offering views of the outside.
A modern hotel lobby with a breakfast bar, seating area, and a large window.

15. SpringHill Suites by Marriott Gainesville

SpringHill Suites by Marriott Gainesville
Gainesville
United States
Robert
CA $127
CA $143 total
includes taxes & fees
Oct 12 - Oct 13
SpringHill Suites by Marriott Gainesville
A spacious living area with a curved ceiling, a large flat-screen TV, and a modern sofa.
A modern kitchen with a curved island, pendant lighting, and a map of Gainesville on the wall.
A modern interior with a seating area, large windows, and a stone wall with a menu.
A modern lounge area with seating arrangements, a flat-screen TV, and artwork on the walls.

16. Holiday Inn Gainesville - University Center by IHG

Holiday Inn Gainesville - University Center by IHG
University Heights
United States
Joseph
CA $150
CA $168 total
includes taxes & fees
Oct 7 - Oct 8
Holiday Inn Gainesville - University Center by IHG
An outdoor kitchen with a grill, a table, and chairs.
A modern kitchen with wooden cabinets, a dishwasher, and a microwave. There is a dining area with a table and chairs, and a living room with a sofa and a TV.
A hotel room with a bed, a sofa, a desk, and a painting on the wall.
A compact hotel room with a kitchenette, a sofa, a dining table, and a small office area.

17. Home2 Suites by Hilton Gainesville Medical Center

Home2 Suites by Hilton Gainesville Medical Center
Gainesville
United States
Karri
CA $156
CA $176 total
includes taxes & fees
Oct 11 - Oct 12
Home2 Suites by Hilton Gainesville Medical Center
A modern bar area with a long counter, green bar stools, and a television displaying a golf game.
A modern hotel room with a large bed, a desk, a chair, and a TV mounted on the wall.
A Fairfield Inn & Suites Marriott hotel with a modern entrance, multiple floors, and a parking lot.
A modern kitchen with a central island, bar stools, pendant lighting, and a dining area with a sofa and chairs.

18. Fairfield Inn & Suites by Marriott Gainesville I-75

Fairfield Inn & Suites by Marriott Gainesville I-75
Gainesville
United States
Robert
CA $170
CA $191 total
includes taxes & fees
Oct 11 - Oct 12
Fairfield Inn & Suites by Marriott Gainesville I-75
A modern hotel with a flat roof, multiple floors, and a prominent 'aloft' sign.
A modern lounge area with sofas, round tables, and a neon sign.
A modern outdoor seating area with multiple sofas and chairs, a covered section with umbrellas, and a view of a building with large windows.
A modern dining area with a pool table, chairs, and a colorful rug.

19. Aloft by Marriott Gainesville University Area

Aloft by Marriott Gainesville University Area
Gainesville
United States
Elizabeth H
CA $140
CA $157 total
includes taxes & fees
Oct 12 - Oct 13
Aloft by Marriott Gainesville University Area
A person pouring a drink into a glass.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A conference room with rows of green chairs, a large screen, and two chandeliers.
A landscaped courtyard with palm trees, a well-maintained lawn, and a building with multiple windows and balconies.

20. Hotel Indigo Gainesville-Celebration Pointe by IHG

Hotel Indigo Gainesville-Celebration Pointe by IHG
Gainesville
United States
Arleana
CA $151
CA $172 total
includes taxes & fees
Oct 11 - Oct 12
Hotel Indigo Gainesville-Celebration Pointe by IHG
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Learn more about Melrose

Nestled along Lake Santa Fe, this charming town offers peaceful kayaking and fishing at Melrose Bay Park. Art lovers can browse local galleries and studios, then enjoy fresh farm-to-table dining at the weekend farmers' market.

See all hotels in Melrose
A waterfront with Spanish moss-covered trees, a wooden dock, and a distant shoreline.
Photo by Matt Mateo

Top Melrose Hotel Reviews

3 Bedroom House on Private Scenic Lake Mable

3 Bedroom House on Private Scenic Lake Mable

10/10 Excellent
"We stayed at this cute place for 2 nights and loved it! Definitely plan to be back."
Alicia C. 2-night trip
Posted 4 hours ago
3 Bedroom House on Private Scenic Lake Mable
Gainesville Lodge

Gainesville Lodge

10/10 Excellent
"Will be booking here again and again whenever needing a place to stay in Gainesville. The rooms are clean, comfortable, and there's not enough love in the world to give to the staff."
Evangeline 2-night trip
Posted 1 day ago
Gainesville Lodge
Days Inn by Wyndham Gainesville Hospital/University Area

Days Inn by Wyndham Gainesville Hospital/University Area

10/10 Excellent
"The room was smoke free and very clean. I wish all properties could that clean and smoke free place. Also the bed,cabinets were made of good and strong materials"
ABDUL-HANAN 1-night trip
Posted 1 day ago
Days Inn by Wyndham Gainesville Hospital/University Area
Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL

10/10 Excellent
"The housekeepers should have checked behind the furniture prior to clearing it for the next occupants. The windows are not noise-quiet; we heard police sirens; motorists doing wheelies, and etc., during the nights. The parking was great. I Unable to eat breakfast due to a medical procedure next morning."
William 1-night trip
Posted 3 days ago
Country Inn & Suites by Radisson, Gainesville, FL
Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville

8/10 Good
"Everything was great!"
MARIA 3-night trip
Posted 6 days ago
Red Roof Inn PLUS+ Gainesville

More cheap stays in Melrose

Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville

3500 Southwest 42nd St Gainesville FL
CA $77
CA $87 total
Oct 7 - Oct 8
includes taxes & fees
Red Roof Inn PLUS+ Gainesville
HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western

3905 Sw 43Rd St Gainesville FL
CA $110
CA $123 total
Oct 11 - Oct 12
includes taxes & fees
8.6/10 Excellent! (2,150 reviews)
HOM Hotel Gainesville, SureStay Collection by Best Western
Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands

4110 SW 40th Boulevard Gainesville FL
CA $108
CA $129 total
Oct 26 - Oct 27
includes taxes & fees
Sleep Inn & Suites University/Shands
Comfort Inn Gainesville - University Area

Comfort Inn Gainesville - University Area

3440 SW 40th Blvd Gainesville FL
CA $114
CA $136 total
Oct 15 - Oct 16
includes taxes & fees
Comfort Inn Gainesville - University Area
Comfort Suites Gainesville near University

Comfort Suites Gainesville near University

2603 SW 13TH STREET Gainesville FL
CA $118
CA $137 total
Oct 11 - Oct 12
includes taxes & fees
Comfort Suites Gainesville near University
Quality Inn & Suites Palatka Riverfront

Quality Inn & Suites Palatka Riverfront

201 N 1st Street Palatka FL
CA $125
CA $139 total
Nov 1 - Nov 2
includes taxes & fees
Quality Inn & Suites Palatka Riverfront

Hotels in Melrose with star rating

Frequently asked questions

What is the best area to stay in Melrose?
The best area to stay in Melrose is typically around the shores of Lake Melrose, particularly on the northern and western sides.This area provides direct access to the lake, which is the heart of Melrose's recreational activities. Properties here often feature private docks, offering convenience for those who enjoy boating, fishing, or simply relaxing by the water. The main roads like State Road 21 run nearby, providing easy access to local shops and eateries while still maintaining a peaceful, residential feel.Families often find this area ideal due to the focus on outdoor activities. Children can enjoy swimming, kayaking, or paddleboarding directly from their accommodation, and the open spaces around the lake are great for playing. The proximity to nature trails also offers opportunities for family walks and exploring the local wildlife.Couples looking for a peaceful retreat will appreciate the quiet surroundings and scenic views of the lake. Many accommodations in this area offer private settings, great for romantic evenings watching the sunset over the water or enjoying a quiet morning coffee on a lakeside porch.
When is the best time to go to Melrose?
The best time to go to Melrose, Florida, is during the spring (March to May) and autumn (September to November) months.During these periods, the weather is pleasantly warm with lower humidity, making it ideal for enjoying outdoor activities. Average temperatures range from 20-28°C (68-82°F), great for exploring the natural beauty of the area, like kayaking on Lake Santa Fe or hiking in the nearby state parks. These seasons also avoid the peak summer heat and the higher risk of hurricanes.Couples looking for a peaceful escape will appreciate the quieter atmosphere during these shoulder seasons. You can enjoy strolls through the small town centre, visit local antique shops, or have a relaxed meal at one of the lakeside restaurants without the larger crowds of peak tourist times.Families will find these times suitable for outdoor adventures. The comfortable temperatures mean children can comfortably explore the parks and enjoy water activities without the intensity of summer heat.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Melrose.
How much is the nightly rate at a Melrose hotel?
Prices for hotels in Melrose often vary, but you can find a great deal from CA $72 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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