Book The Best Hotels in Lupus, MO for 2026 from CA $84 - Fully Refundable Options

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Our top choices for Lupus hotels

A hotel lobby with a reception desk, seating area, and a reception counter.

A dining area with tables and chairs, a kitchen in the background, and a patterned carpet.

A compact hotel room with a flat-screen TV, a microwave, a refrigerator, a bench, and a small table.

A gym with a treadmill, exercise bike, and weight machine.

1. Baymont by Wyndham Columbia, MO

Columbia

Susan

CA $87

CA $98 total

includes taxes & fees

Oct 25 - Oct 26

A modern office space with a meeting area featuring a large table and chairs, a purple accent wall, and a view through large windows.

A modern office space with a desk area, seating, and a hanging chair.

2. Tru By Hilton Columbia South

Columbia

Kevin M.

CA $127

CA $145 total

includes taxes & fees

Oct 27 - Oct 28

A patio area with a fire pit, outdoor seating, and a grill.

A modern kitchen with built-in appliances, a wooden countertop, and a seating area with a chair.

A modern dining area with a long wooden table, multiple chairs, a flat-screen TV mounted on a stone wall, and a fireplace.

A modern building with a 'park' sign, stone facade, and outdoor seating area.

3. TownePlace Suites by Marriott Columbia

Columbia

Barb

CA $168

CA $191 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a dining area, a sofa, a TV, and a view of the city.

A hotel room with a large bed, two bedside tables with lamps, a desk with a computer, and a large window offering a view of the city.

A Wyndham hotel with a prominent illuminated sign, a covered entrance, and a parking area.

A banquet hall with round tables set for a formal event, featuring a patterned carpet and a high ceiling with chandeliers.

4. Wyndham Executive Center Columbia

Columbia

Shara

CA $135

CA $153 total

includes taxes & fees

Oct 30 - Oct 31

A modern interior with round tables and chairs, a bar area, and a large window offering a view of the outside.

A modern lounge area with a sofa, round tables, and chairs, a kitchen area, and large windows.

A modern lobby with a sofa, chairs, a table, a TV, and a reception desk.

A multi-story hotel with a covered entrance and a stone facade.

5. Best Western Plus Columbia Inn

Columbia

Shawn

CA $110

CA $124 total

includes taxes & fees

Oct 19 - Oct 20

A modern living room with grey sofas, a coffee table, and a fireplace. There are framed pictures on the wall and a floor lamp.

A hotel room with a large bed, a desk with a lamp, a kitchenette, and a bathroom.

A reception desk with a wooden finish, three pendant lights, framed artwork on the wall, and a small display case with pastries.

A large indoor swimming pool with a tiled edge, a metal ladder, and lounge chairs around the perimeter.

6. Country Inn & Suites by Radisson, Columbia, MO

Columbia

Nadine

CA $119

CA $135 total

includes taxes & fees

Nov 15 - Nov 16

A modern lobby with a sectional sofa, a flat-screen TV, and a glass wall offering a view of the city.

A gym with treadmills, elliptical machines, and a bench.

A restaurant interior with booths and tables, blue cushioned chairs, and framed pictures on the walls.

A hotel room with a large bed, a sofa, a desk, and a television.

7. Drury Inn & Suites Columbia Stadium Boulevard

Columbia

Joseph

CA $142

CA $160 total

includes taxes & fees

Oct 25 - Oct 26

A lobby with a reception desk, two sofas, a coffee table, and a patterned rug.

A hotel room with a large bed, a desk with a flat-screen TV, a chair, a desk lamp, and a nightstand with a lamp.

A hotel room with a bed, a dining table with chairs, a sofa set, a small table, and a kitchenette.

A modern restaurant with high tables and booths, large windows, and a patterned carpet.

8. Wingate by Wyndham - Columbia

Columbia

Carlos

CA $122

CA $138 total

includes taxes & fees

Oct 25 - Oct 26

An indoor swimming pool with clear signage indicating no lifeguard on duty and no diving.

A Hampton Inn & Suites hotel with a brick facade, a covered entrance, and a parking lot.

A reception desk with a wooden finish and granite counter, a framed welcome sign, and a lamp.

A wedding reception table with a tiered white cake, floral decorations, and a menu stand.

9. Hampton Inn & Suites Columbia at University

Columbia

Jamie

CA $167

CA $189 total

includes taxes & fees

Nov 1 - Nov 2

A covered outdoor seating area with wooden beams and a lantern, overlooking a brick building and greenery.

A modern interior with a seating area, wooden partitions, and large windows.

A hotel room with a bed, a chair, a floor lamp, and a painting on the wall.

A modern gym with treadmills, weight machines, and free weights.

10. Courtyard by Marriott Columbia Missouri

Columbia

Jeremy

CA $162

CA $183 total

includes taxes & fees

Oct 25 - Oct 26

A hotel entrance with a covered walkway, a brick facade, and a well-lit exterior.

A buffet with labeled containers of omelets and other food items.

A large indoor swimming pool with multiple lanes, surrounded by lounge chairs and tables.

A lobby with four armchairs, a coffee table, and a floor lamp. There are two wall-mounted light fixtures and a decorative wall piece.

11. Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Columbia

Jennifer

CA $163

CA $185 total

includes taxes & fees

Nov 15 - Nov 16

An indoor swimming pool with wooden beams, stone walls, and artificial trees.

A rustic interior with wooden tables and chairs, a fireplace, and a stone wall.

A log cabin-style room with a bed, a fireplace, a stone wall, a TV, and a large window.

A spacious lobby with a wooden staircase and a second-floor balcony.

12. Stoney Creek Hotel Columbia

Columbia

Brett

CA $153

CA $172 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a large bed, a separate sitting area, a bathroom with a bathtub, and a large mirror.

A gym with treadmills, elliptical machines, and a stationary bike.

A self-service breakfast bar with coffee machines, a microwave, and various food options.

A hotel room with a red accent wall, a framed world map, a white sofa, a desk with a lamp, and a door leading to another room.

13. Ramada by Wyndham Columbia

Columbia

Andrew

CA $90

CA $102 total

includes taxes & fees

Oct 25 - Oct 26

A spacious living area with a blue sofa, leather armchairs, and a flat-screen TV mounted on a wooden cabinet. Large windows provide a view of parked cars outside.

A hotel lobby with a reception desk, a blue sofa, and a patterned rug.

A hotel room with a large bed, a desk, a chair, a lamp, and a window with curtains.

A hotel room with a large flat-screen TV, two beds, a sofa, and a desk.

14. Comfort Suites Columbia - University Area

Columbia

Lisa

CA $152

CA $172 total

includes taxes & fees

Oct 25 - Oct 26

A spacious indoor area with multiple seating arrangements, including tables and chairs, a television, and a fireplace.

A corner sofa with two patterned pillows, a flat-screen TV on a wooden stand, and a window with curtains.

A hotel reception area with a wooden reception desk, a clock on the wall, and a sign indicating 'Quality by Choice Hotels'.

A hotel room with two beds, a desk, a TV, and a window with curtains.

15. Quality Inn & Suites Columbia I-70

Columbia

Nathan

CA $96

CA $108 total

includes taxes & fees

Nov 10 - Nov 11

A hotel room with a bed, two bedside lamps, a nightstand, a TV, a mirror, a bathroom with a bathtub, and a large painting on the wall.

A spacious living room with a stone fireplace, a large window, and a high ceiling.

A modern living room with a sofa, chairs, and a dining area with tables and chairs.

A lobby with a reception desk, leather sofa, armchair, wooden side table, and a small rug.

16. Super 8 by Wyndham Columbia East

Columbia

Roy

CA $75

CA $85 total

includes taxes & fees

Nov 10 - Nov 11

A spacious bar area with high tables and chairs, a large flat-screen TV mounted on the wall, and a bar stocked with bottles.

An indoor swimming pool with a tiled floor, a glass barrier, and a lifeguard chair.

A modern bar area with a long counter, bar stools, and a fireplace.

A hotel room with two beds, a large window with curtains, and a carpeted floor.

17. Drury Plaza Hotel Columbia East

Columbia

Kevin

CA $145

CA $164 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a bed, a desk, a kitchenette, and a bathroom.

A modern kitchen with wooden cabinets, stainless steel appliances, and a white countertop.

A modern dining area with multiple tables and chairs, a kitchen in the background, and a television mounted on the wall.

A modern hotel room with a kitchen area, a dining table, a sofa, and a TV.

18. Staybridge Suites Columbia by IHG

Columbia

Isabelle

CA $141

CA $159 total

includes taxes & fees

Oct 25 - Oct 26

A hotel lobby with a reception desk, a coffee machine, a small table with a lamp, and framed artwork on the walls.

A hotel room with two beds, each with a patterned quilt, a nightstand, and a wall-mounted lamp.

A Budget Inn with a prominent sign, a covered entrance, and a small garden area with potted plants.

19. Midway Budget Inn

Columbia

HEATH

CA $122

CA $129 total

includes taxes & fees

Oct 17 - Oct 18

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving allowed.

A hotel room with a sofa, armchair, and a small table. There is a lamp, a bed, and a kitchenette with a sink and a microwave.

A hotel room with a large bed, a desk with a television, a chair, a lamp, and a window with curtains.

A restaurant with booths and tables, a curved ceiling, and a slogan on the wall.

20. Holiday Inn Columbia East by IHG

Columbia

Tracy

CA $177

CA $206 total

includes taxes & fees

Oct 22 - Oct 23

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Stay near popular Lupus attractions

Lupus Park

After visiting Lupus Park, make a plan to see the other sights and activities in Lupus.

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Top Lupus Hotel Reviews

Stoney Creek Hotel Columbia

10/10 Excellent

"Room was clean and uncluttered. Parking was close to the elevator hallway. Bar is open at 4pm, closes late and has an outdoor seating area. Breakfast area is large enough to handle a crowd without being tight and the food is above average for breakfast. There is a Waffle House down the street for more options."

Drury Plaza Hotel Columbia East

8/10 Good

"Dirty/full trash can in the bathroom"

Wingate by Wyndham - Columbia

10/10 Excellent

"We stayed one night traveling through. The staff was very friendly. The room was clean and very nice. Breakfast was hot food and prepared well. Lots os space in the dining area."

Isle of Capri Casino Hotel Boonville & Casino - A Caesars Rewards Destination

8/10 Good

"We were on the Katy Trail then our bikes were accommodated, the beds were comfortable no issues there. Our biggest complaints were staff inside the casino and the restaurant. Never being in a casino before I didn't know how to go about anything. And where you get your players card lets just say after multiple visits to the counter we finally got it figured out. Bar staff and floor staff were great. At the restaurant we ordered at 9:20pm for a 10pm close. The waitress didn't check on us after our food was delivered until 10pm and then I tried to order a 2nd sandwich to go because it was so good. She tried to inform me it was to late to order. I stated if she had come to check on us in the last 20 minutes it wouldn't be to late. She reluctantly put it in and informed us she was doing her closing stuff. We never got offered desserts either I'm sure because getting out was more important than costumer service. Funny thing is if she had touched our table more we would have been able to have dessert and not have to go to the bar for drinks refills. So the restaurant was they least favorite part, and it didn't have to be."

Days Inn by Wyndham Boonville

10/10 Excellent

"Wonderful staff"

Ramada by Wyndham Columbia

8/10 Good

"Clean room, quick check in"

The Broadway Columbia - a DoubleTree by Hilton

10/10 Excellent

"Perfect place to stay if you are going to a Missouri football game. It is close to everything. The staff was very friendly and helpful when needed. The rooftop bar was amazing."

Drury Inn & Suites Columbia Stadium Boulevard

10/10 Excellent

"All of the staff was excellant. Went out of their way to welcome us."

Step Back in Time Near The Missouri River

10/10 Excellent

"Very clean, awesome decor. We loved the peace and quiet, the house was clean, plenty of room, and the host, Andrew was friendly and easy to work with!"

More cheap stays in Lupus

Hotel Blu

3402 Interstate 70 Dr SE Columbia MO

CA $75

CA $84 total

Oct 20 - Oct 21

includes taxes & fees

Baymont by Wyndham Columbia, MO

2500 I 70 Dr Sw Columbia MO

CA $87

CA $98 total

Oct 25 - Oct 26

includes taxes & fees

Ramada by Wyndham Columbia

901 Conley Rd Columbia MO

CA $90

CA $102 total

Oct 25 - Oct 26

includes taxes & fees

7.4/10 Good! (1,003 reviews)

Best Western Plus Columbia Inn

2904 Clark Lane Columbia MO

CA $110

CA $124 total

Oct 19 - Oct 20

includes taxes & fees

Country Inn & Suites by Radisson, Columbia, MO

817 N Keene St Columbia MO

CA $119

CA $135 total

Nov 15 - Nov 16

includes taxes & fees

Stoney Creek Hotel Columbia

2601 S Providence Rd Columbia MO

CA $153

CA $172 total

Oct 25 - Oct 26

includes taxes & fees

8.6/10 Excellent! (1,417 reviews)

Hotels in Lupus with star rating

Frequently asked questions

When is the best time to go to Lupus?

The best time to visit Lupus, Missouri, is during the spring (April to May) and autumn (September to October) months.These seasons offer pleasant weather, with mild temperatures and lower humidity, making outdoor activities and exploring the scenic Missouri River bluffs more enjoyable. Spring brings blooming wildflowers, while autumn showcases beautiful fall foliage, adding to the area's natural beauty.For those looking to participate in local agricultural events or enjoy the outdoors without the intense summer heat, these periods are ideal.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lupus.

How much is the nightly rate at a Lupus hotel?

Prices for hotels in Lupus often vary, but you can find a great deal from CA $84 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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Missouri Vacation Rentals

Book Hotels in Lupus on Expedia.com

Find hotels in Lupus, MO from CA $84

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Lupus

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lupus hotels

1. Baymont by Wyndham Columbia, MO

2. Tru By Hilton Columbia South

3. TownePlace Suites by Marriott Columbia

4. Wyndham Executive Center Columbia

5. Best Western Plus Columbia Inn

6. Country Inn & Suites by Radisson, Columbia, MO

7. Drury Inn & Suites Columbia Stadium Boulevard

8. Wingate by Wyndham - Columbia

9. Hampton Inn & Suites Columbia at University

10. Courtyard by Marriott Columbia Missouri

11. Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

12. Stoney Creek Hotel Columbia

13. Ramada by Wyndham Columbia

14. Comfort Suites Columbia - University Area

15. Quality Inn & Suites Columbia I-70

16. Super 8 by Wyndham Columbia East

17. Drury Plaza Hotel Columbia East

18. Staybridge Suites Columbia by IHG

19. Midway Budget Inn

20. Holiday Inn Columbia East by IHG

Stay near popular Lupus attractions

Lupus Park

Top Lupus Hotel Reviews

Stoney Creek Hotel Columbia

Drury Plaza Hotel Columbia East

Wingate by Wyndham - Columbia

Isle of Capri Casino Hotel Boonville & Casino - A Caesars Rewards Destination

Days Inn by Wyndham Boonville

Ramada by Wyndham Columbia

The Broadway Columbia - a DoubleTree by Hilton

Drury Inn & Suites Columbia Stadium Boulevard

Step Back in Time Near The Missouri River

More cheap stays in Lupus

Hotel Blu

Baymont by Wyndham Columbia, MO

Ramada by Wyndham Columbia

Best Western Plus Columbia Inn

Country Inn & Suites by Radisson, Columbia, MO

Stoney Creek Hotel Columbia

Hotels in Lupus with star rating

Frequently asked questions

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