West Main Historic District

Louisville

Louisville Science Center which includes outdoor art
Louisville Science Center which includes outdoor art
Kentucky Center for the Performing Arts featuring modern architecture
Louisville Science Center showing signage
Belle of Louisville featuring a bay or harbor and a ferry

Popular places to visit

Things to do


West Main Historic District Hotel Deals

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
The price is CA $173 per night from Mar 22 to Mar 23
CA $173
CA $203 total
Mar 22 - Mar 23
includes taxes & fees
Book a stay at this spa hotel in Louisville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the restaurant and the helpful staff ...
9/10 Wonderful! (4,091 reviews)
No microwave, pullout sofa, trash bags for cans or extra sheets. Just a one night stay but these are basic things.

Reviewed on Mar 2, 2026

Galt House Hotel Trademark Collection by Wyndham
Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street Louisville KY
The price is CA $250 per night from Mar 29 to Mar 30
CA $250
CA $294 total
Mar 29 - Mar 30
includes taxes & fees
Book a stay at this spa hotel in Louisville. Enjoy a full-service spa, 3 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,784 reviews)
The staff at the Omni provided outstanding customer service that exceeded our expectations. They were quick to provide solutions and answer our questions. Terrence and Amanda went out of their way to make sure our stay was top notch. They were kind, polite and provided excellent, charismastic, customer ...

Reviewed on Mar 2, 2026

Omni Louisville Hotel
Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown

3.5 out of 5
350 West Chestnut Street Louisville KY
The price is CA $133 per night from Apr 5 to Apr 6
CA $133
CA $157 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8.4/10 Very Good! (1,002 reviews)
Comfortable

Reviewed on Mar 2, 2026

Hilton Garden Inn Louisville Downtown
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4 out of 5
501 South Fourth Street Louisville KY
The price is CA $157 per night from Mar 15 to Mar 16
CA $157
CA $185 total
Mar 15 - Mar 16
includes taxes & fees
Stay at this hotel in Louisville. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in ...
9/10 Wonderful! (1,159 reviews)
Clean. Great lobby and location with friendly staff!

Reviewed on Mar 4, 2026

Embassy Suites Louisville Downtown
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

2.5 out of 5
800 W Market St Louisville KY
The price is CA $121 per night from Mar 8 to Mar 9
CA $121
CA $143 total
Mar 8 - Mar 9
includes taxes & fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,714 reviews)
Clean, quiet, very comfortable

Reviewed on Mar 4, 2026

Holiday Inn Express & Suites Louisville Downtown by IHG
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 out of 5
700 W Main Street Louisville KY
Fully refundableReserve now, pay when you stay
The price is CA $244 per night from Mar 19 to Mar 20
CA $244
CA $294 total
Mar 19 - Mar 20
includes taxes & fees
Book a stay at this luxury hotel in Louisville. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
9.4/10 Exceptional! (1,007 reviews)
Lovely hotel. Would stay there again.

Reviewed on Mar 5, 2026

21c Museum Hotel Louisville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

Other neighbourhoods around West Main Historic District

Landscape of Louisville

Downtown Louisville

4/5(37 area reviews)

Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk.

Downtown Louisville
What's in a name?

Well, oddly enough, at Cave Hill Cemetery, there's a hill, with a cave.

A natural spring spills forth from this 246 ft deep cave. Standing upright, the cave could be explored for about 100ft. No, it's not allowed... There is a colony of bats that inhabit the cave. Bats pouring from a cave at dusk in a cemetery would be quite a visual.

Phoenix Hill

While Phoenix Hill isn't home to many top sights, Nulu Market Place and Thomas Edison House are some notable places to visit nearby.

Phoenix Hill
Big Four Bridge across Ohio River between Louisville, Kentucky and Jeffersonville, Indiana

East Market District

While there might not be top attractions in East Market District, you can explore the larger area and discover places like Nulu Market Place and Thomas Edison House.

East Market District
Old Louisville Home

Old Louisville

2.5/5(11 area reviews)

Boasting Victorian architecture and the highest concentration of stained glass windows in residential homes, Old Louisville offers a walkable neighborhood with pedestrian-only streets, diverse dining options, and attractions like Central Park and the Conrad-Caldwell House.

Old Louisville
View of  Skyline downtown Louisville

Smoketown Jackson

While there might not be top attractions in Smoketown Jackson, you can explore the larger area and discover places like Louisville Palace and Nulu Market Place.

Smoketown Jackson
Default Image

Shelby Park

If you're looking for some top things to see and do in Shelby Park and surrounding area, you can visit Conrad-Caldwell House Museum and Landward House.

Shelby Park


West Main Historic District

Choose two or more items and save on your trip: