Title: Lewis and Clark Trail Trailhead in St. Louis - Tours and Activities | Expedia.ca [Lewis and Clark Trail Trailhead Hotels](https://expedia.ca/Lewis-And-Clark-Trail-Trailhead-Hotels.0-l641530008594042880-0.Travel-Guide-Filter-Hotels)[Flights to St. Louis](https://expedia.ca/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.ca/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[Lewis and Clark Trail Trailhead Car Rentals](https://expedia.ca/Car-Rentals-In-Lewis-And-Clark-Trail-Trailhead.d641530008594042880.Car-Rental-Guide)[St. Louis Vacation Packages](https://expedia.ca/St-Louis.d178309.Destination-Travel-Guides) # Lewis and Clark Trail Trailhead Tours and Activities ## Visit Lewis and Clark Trail Trailhead Activities [St. Louis travel guide](https://expedia.ca/St-Louis.dx178309) --- --- ## Plan a trip to see Lewis and Clark Trail Trailhead Price found within the past 48 hours. Click for updated prices. ![Sonesta ES Suites St. Louis - Chesterfield](https://images.trvl-media.com/lodging/1000000/10000/500/422/a42ce99e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Sonesta ES Suites St. Louis - Chesterfield CA $1,317 per person Mar 20 - Mar 22 found 1 day ago Roundtrip flight included Saskatoon (YXE) to St. Louis (STL) 8/10 Very Good! (1,018 reviews) There are many dogs at the property and unfortunately most people do not pick up the excrement of their animal which is disturbing. The property is not kept clean enough. The rooms have very old furniture and carpeting that needs a refresh. I had them come and reclean the room and it was better. Reviewed on Jan 2, 2026 ![DoubleTree by Hilton Hotel St. Louis - Chesterfield](https://images.trvl-media.com/lodging/1000000/10000/3300/3258/47e1344b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### DoubleTree by Hilton Hotel St. Louis - Chesterfield CA $1,427 per person Mar 20 - Mar 22 found 1 day ago Roundtrip flight included Saskatoon (YXE) to St. Louis (STL) 8.6/10 Excellent! (1,001 reviews) Clean rooms, comfortable beds, kind and helpful staff such as Kim, Brandon at the front desk, Michelle our house keeper were all fantastic. Reviewed on Nov 26, 2025 ![Angad Arts Hotel St. Louis, Tapestry Collection by Hilton](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton Grand Center CA $1,529 per person Mar 20 - Mar 22 found 1 day ago Roundtrip flight included Saskatoon (YXE) to St. Louis (STL) 8.8/10 Excellent! (1,022 reviews) It was good and beautiful on the inside. Loved all the art. The bed was comfy and the room was like an apartment .The only thing that stunk is that there wasn't a microwave in the room. But there was one on the floor so it worked out. Reviewed on Feb 3, 2026 ### Popular places to visit ![Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri](https://images.trvl-media.com/place/6160337/5138d652-49fb-41de-8fd4-a7bb27471f3e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### August A. Busch Memorial Conservation Area Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savor the top-notch restaurants. [](https://expedia.ca/August-A-Busch-Memorial-Conservation-Area-St-Louis.d6160337.Vacation-Attraction) ![9-11 memorial in New York ](https://images.trvl-media.com/place/6268196/1e2df18b-5a0c-4e2a-9bc0-6956a83c47d9.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 9-11 Memorial Learn about the local history of O'Fallon when you spend time at 9-11 Memorial. While in this family-friendly area, you can savor the top-notch restaurants. [](https://expedia.ca/9-11-Memorial-St-Louis.d6268196.Vacation-Attraction) ![Missouri wineries have some of the most superb wine we've ever tasted! We recommend sipping on some chambourcin while basking in the sunshine. ](https://images.trvl-media.com/place/553248621532648567/f82f9409-75a2-47f3-a8fc-2d7c278cc07c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Chandler Hill Vineyards You can enjoy a tasting or tour at Chandler Hill Vineyards during your travels to Defiance. While in this romantic area, you can savor the top-notch restaurants. [](https://expedia.ca/Chandler-Hill-Vineyards-Defiance.d553248621532648567.Vacation-Attraction) #### Weldon Spring Site Interpretive Center You can spend time browsing the exhibits at Weldon Spring Site Interpretive Center during your trip to Weldon Spring Heights. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants. [](https://expedia.ca/Weldon-Spring-Site-Interpretive-Center-St-Louis.d553248621532648611.Vacation-Attraction) #### Hamburg Trail Trailhead You can take time to visit Hamburg Trail Trailhead during your travels to Hamburg. [](https://expedia.ca/Hamburg-Trail-Trailhead-St-Louis.d641529175733194752.Vacation-Attraction) #### Missouri Bluffs Golf Course Enjoy a round of golf in Weldon Spring Heights at Missouri Bluffs Golf Course. Experience the great live music or attend a sporting event in this family-friendly area. [](https://expedia.ca/Missouri-Bluffs-Golf-Course-St-Louis.d553248621532648614.Vacation-Attraction) --- ## Best Lodging Options Near Lewis and Clark Trail Trailhead ## Check availability on hotels close to Lewis and Clark Trail Trailhead [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=641530008594042880&startDate=2026-02-08&endDate=2026-02-09)[Feb 8 - Feb 9](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=641530008594042880&startDate=2026-02-08&endDate=2026-02-09) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=641530008594042880&startDate=2026-02-09&endDate=2026-02-10)[Feb 9 - Feb 10](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=641530008594042880&startDate=2026-02-09&endDate=2026-02-10) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=641530008594042880&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026)[Feb 13 - Feb 15](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=641530008594042880&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026) ![Holiday Inn Express & Suites St. Louis - Chesterfield by IHG](https://images.trvl-media.com/lodging/24000000/23060000/23052900/23052829/c359eef2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Express & Suites St. Louis - Chesterfield by IHG 11 Arnage Boulevard Chesterfield MO [](https://expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-Suites-St-Louis-Chesterfield.h23052829.Hotel-Information) ![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Wildwood Hotel 2801 Fountain Pl Wildwood MO [](https://expedia.ca/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) ![Comfort Inn & Suites St. Louis - O'Fallon](https://images.trvl-media.com/lodging/1000000/930000/922100/922031/7c698b9f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfort Inn & Suites St. Louis - O'Fallon 100 Comfort Inn Ct O'Fallon MO [](https://expedia.ca/St-Louis-Hotels-Comfort-Inn-Suites-St-Louis-OFallon.h922031.Hotel-Information) ![Hilton Garden Inn Chesterfield](https://images.trvl-media.com/lodging/1000000/300000/297100/297075/c23cebe0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Garden Inn Chesterfield 16631 Chesterfield Grove Ct Chesterfield MO [](https://expedia.ca/St-Louis-Hotels-Hilton-Garden-Inn-Chesterfield.h297075.Hotel-Information) ![Drury Plaza Hotel St. Louis Chesterfield](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/c1fcfc39_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Plaza Hotel St. Louis Chesterfield 355 Chesterfield Ctr Chesterfield MO [](https://expedia.ca/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information) ![Fairfield Inn & Suites by Marriott St. Louis Chesterfield](https://images.trvl-media.com/lodging/1000000/130000/126800/126794/b774ae26_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Fairfield Inn & Suites by Marriott St. Louis Chesterfield 1065 Chesterfield Pkwy E Chesterfield MO [](https://expedia.ca/St-Louis-Hotels-SpringHill-Suites-By-Marriott-St-Louis-Chesterfield.h126794.Hotel-Information) ![Extended Stay America Suites St Louis St Peters](https://images.trvl-media.com/lodging/1000000/70000/66100/66038/w2993h2000x0y0-d823c428_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Extended Stay America Suites St Louis St Peters 5555 Veterans Memorial Pkwy St. Peters MO [](https://expedia.ca/St-Louis-Hotels-Extended-Stay-America-Suites-St-Louis-St-Peters.h66038.Hotel-Information) ![Hampton Inn St. Charles St. Peters](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/8c366380_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn St. Charles St. Peters 3720 W Clay St St. Charles MO [](https://expedia.ca/St-Louis-Hotels-Hampton-Inn-St-LouisSt-Charles.h20181.Hotel-Information) ![Hollywood Casino & Hotel St. Louis](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hollywood Casino & Hotel St. Louis 777 Casino Center Drive Maryland Heights MO [](https://expedia.ca/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information) [See all 2,346 properties in Lewis and Clark Trail Trailhead](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=641530008594042880) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.