Lewis and Clark Trail Trailhead Tours and Activities

Plan a trip to see Lewis and Clark Trail Trailhead

Price found within the past 48 hours. Click for updated prices.
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

2.5 out of 5
per person
Sep 11 - Sep 15
found 7 hours ago
Roundtrip non-stop flight included
Buffalo (BUF) to St. Louis (STL)
9.4/10 Exceptional! (1,353 reviews)
I had scheduled my stay for the wrong date and Mona who was behind the desk was amazing! She talked to Expedia and arranged my stay with no extra fees! She Provided Over and above service. Thank you Mona

Reviewed on Jul. 31, 2025

The Cheshire

The Cheshire

4 out of 5
per person
Sep 11 - Sep 15
found 7 hours ago
Roundtrip non-stop flight included
Buffalo (BUF) to St. Louis (STL)
8.6/10 Excellent! (1,000 reviews)
This is definitely a unique hotel. The book/author themes is kind of cool, but overall it felt very outdated. The giant bear in the lounge area looks like it's been there for 100 years...missing fingers and toes...very dusty. Pool area could be really great if they had less metal tables and more loungers. Breakfast was a bonus.

Reviewed on Aug. 1, 2025

DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield

4 out of 5
per person
Sep 11 - Sep 15
found 7 hours ago
Roundtrip non-stop flight included
Buffalo (BUF) to St. Louis (STL)
8.6/10 Excellent! (1,000 reviews)
Beautiful property, pleasant and responsive staff, delicious warm cookies! And convenient location near city hall and police department.

Reviewed on Jul. 27, 2025

Popular places to visit

August A. Busch Memorial Conservation Area

August A. Busch Memorial Conservation Area

Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savor the top-notch restaurants.

August A. Busch Memorial Conservation Area
Broemmelsiek Park

Broemmelsiek Park

Broemmelsiek Park is just one of the places to see in Defiance, so why not enjoy the other things to explore during your travels? Amble around this family-friendly area's gardens or experience its festivals.

Broemmelsiek Park

Weldon Spring Site Interpretive Center

You can spend time browsing the exhibits at Weldon Spring Site Interpretive Center during your trip to Weldon Spring Heights. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants.

Weldon Spring Site Interpretive Center

Hamburg Trail Trailhead

You can take time to visit Hamburg Trail Trailhead during your travels to Defiance. While you're in the area, wander around the parks.

Hamburg Trail Trailhead

Missouri Bluffs Golf Course

Enjoy a round of golf in Weldon Spring Heights at Missouri Bluffs Golf Course. Experience the great live music or attend a sporting event in this family-friendly area.

Missouri Bluffs Golf Course

St. Louis Premium Outlets

You can enjoy retail therapy at St. Louis Premium Outlets during your stay in Chesterfield. Discover the top-notch restaurants and great live music in this family-friendly area.

St. Louis Premium Outlets

Best Lodging Options Near Lewis and Clark Trail Trailhead

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
2801 Fountain Pl, Wildwood, MO
The Wildwood Hotel
Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield

3 out of 5
333 Chesterfield Center East, Chesterfield, MO
Hyatt Place St. Louis/Chesterfield
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

3 out of 5
15431 Conway Rd, Chesterfield, MO
Sonesta ES Suites St. Louis - Chesterfield
Relax Inn Saint Charles

Relax Inn Saint Charles

2 out of 5
3800 Harry S Truman Blvd, St. Charles, MO
Relax Inn Saint Charles
Country Inn & Suites by Radisson, St. Peters, MO

Country Inn & Suites by Radisson, St. Peters, MO

2.5 out of 5
3877 Veterans Memorial Pkwy, St. Charles, MO
Country Inn & Suites by Radisson, St. Peters, MO
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Hollywood Casino & Hotel St. Louis
Marriott St. Louis West

Marriott St. Louis West

3.5 out of 5
660 Maryville Centre Dr, St. Louis, MO
Marriott St. Louis West
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd, St. Charles, MO
Ameristar Casino Resort and Spa
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

2.5 out of 5
1400 S 5th St, St. Charles, MO
Comfort Suites St Charles - St Louis
See all 2,270 properties in Lewis and Clark Trail Trailhead
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.