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Our top choices for Key West National Wildlife Refuge hotels

A wooden archway leading to a pool area surrounded by lush tropical vegetation.
A beach with palm trees, a sandy shore, and a calm sea under a clear sky.
A tall palm tree with a white building in the background.
A large, two-story building with a symmetrical facade, a central entrance with a double door, and a balcony on the upper floor.

1. Parrot Key Hotel & Villas

Parrot Key Hotel & Villas
Northside Resort, 14.4 km from Key West National Wildlife Refuge
United States
Anthony
CA $203
CA $309 total
includes taxes & fees
Oct 28 - Oct 29
Parrot Key Hotel & Villas
A wooden deck with wicker furniture and a glass balustrade overlooking a beach.
A resort with a pool leading to a beach, surrounded by palm trees and white buildings.
A beach with white lounge chairs and umbrellas, a sandy shore, and a calm sea under a partly cloudy sky.
A spacious lobby with green sofas, a coffee table, and a dining area.

2. Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton
Casa Marina, 12.7 km from Key West National Wildlife Refuge
United States
Charlene
CA $305
CA $439 total
includes taxes & fees
Nov 1 - Nov 2
Casa Marina Key West, Curio Collection by Hilton
A tropical outdoor area with palm trees, hanging plants, and string lights.
A large, two-story building with a balcony, surrounded by dense tropical foliage.
A hotel room with a bed, a wooden floor, a seating area with a table and chairs, and a view of greenery outside.
An outdoor patio with a table and chairs, surrounded by lush greenery and string lights.

3. Douglas House - Adults Only

Douglas House - Adults Only
Uptown - Upper Duval, 11.8 km from Key West National Wildlife Refuge
United States
Maricela
CA $223
CA $275 total
includes taxes & fees
Oct 27 - Oct 28
Douglas House - Adults Only
A large, ornate hotel with a pool, palm trees, and a view of the ocean.
A grand staircase with ornate railings and a chandelier.
A gated entrance with a blue metal gate, palm trees, and a building with a red roof in the background.
A balcony with white railings and a table, overlooking a beach with palm trees and a clear blue sky.

4. Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
Uptown - Upper Duval, 12.1 km from Key West National Wildlife Refuge
United States
Amy
CA $253
CA $464 total
includes taxes & fees
Oct 25 - Oct 26
Southernmost House - Adult Exclusive
A pool area with lounge chairs and palm trees.
A neatly made bed with patterned pillows, a bedside table with a bottle and glasses, and a window with orchids.
A sign for Santa Maria Resort surrounded by lush greenery and palm trees.
A modern outdoor seating area with a sofa, chairs, and a small table, surrounded by glass doors and a view of greenery.

5. Santa Maria Suites

Santa Maria Suites
Uptown - Upper Duval, 12.2 km from Key West National Wildlife Refuge
United States
Anthony
CA $423
CA $571 total
includes taxes & fees
Oct 26 - Oct 27
Santa Maria Suites
A beach with a wooden pier, palm trees, and beach umbrellas.
An outdoor dining area with tables and chairs, overlooking the ocean.
A resort with a pool, lounge chairs, umbrellas, palm trees, and a view of the ocean.
A modern bar area with a central island, white bar stools, and a view of the ocean.

6. The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
Uptown - Upper Duval, 12.3 km from Key West National Wildlife Refuge
United States
Brett
CA $225
CA $348 total
includes taxes & fees
Oct 28 - Oct 29
The Reach Key West, Curio Collection by Hilton
A covered porch with wicker furniture, potted plants, and a sign for the "Office" at the Palm Hotel.
A compact kitchen with white cabinets, a microwave, and a small dining area with two wicker chairs.
A pink building with a white door, a balcony with a white railing, and a view of a pool area.
A row of bicycles parked in front of a building with a white balcony and a palm tree.

7. The Palms Hotel

The Palms Hotel
The Meadows, 12.5 km from Key West National Wildlife Refuge
United States
Jerry
CA $227
CA $287 total
includes taxes & fees
Oct 25 - Oct 26
The Palms Hotel
A modern outdoor area with a pool, lounge chairs, and a bar area.
An outdoor seating area with a modern fire feature, surrounded by lush greenery and palm trees.
A bar area with a modern design, featuring a flat-screen TV mounted on a textured wall, two stools, and a bar stocked with various bottles.
A modern hotel with a prominent glass facade, palm trees, and a clear sky.

8. H2O Suites - Adults Only

H2O Suites - Adults Only
Uptown - Upper Duval, 12.1 km from Key West National Wildlife Refuge
United States
Carmen
CA $443
CA $593 total
includes taxes & fees
Oct 28 - Oct 29
H2O Suites - Adults Only
A swimming pool with water splashing, surrounded by palm trees and a building in the background.
The exterior of the Silver Palms Inn with a two-story structure, a green awning over the entrance, and a palm tree to the right.
The entrance to Silver Palms Inn with a reception desk, a seating area, and a glass door.
A two-story yellow house with a porch, white railings, and green shutters.

9. Silver Palms Inn & Historic Homes

Silver Palms Inn & Historic Homes
Old Town Key West, 12.2 km from Key West National Wildlife Refuge
United States
sam
CA $126
CA $237 total
includes taxes & fees
Oct 25 - Oct 26
Silver Palms Inn & Historic Homes
A modern hotel room with a large bed, a nightstand, a bedside table, and a bathroom visible through an open door.
A building with a sign reading "ALMOND Frog & Toad Inn" and a "VACANCY" sign below it.
A swimming pool with lounge chairs, surrounded by palm trees and greenery.
A reception area with a wooden herringbone wall, teal chairs, a wooden bench, and two framed sunset paintings.

10. Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
Downtown Key West, 11.8 km from Key West National Wildlife Refuge
United States
Teresa
CA $369
CA $415 total
includes taxes & fees
Oct 26 - Oct 27
Almond Tree Inn Hotel - Adults Only
A wooden deck with white railings, surrounded by lush greenery and a staircase leading to a building.
A swimming pool with a mural of a dolphin and a butterfly, surrounded by lounge chairs and palm trees.
A hallway with a white door, a wooden bench, a blue sofa, and a staircase with a white railing.
A lush garden with a variety of tropical plants and a paved walkway.

11. Duval House

Duval House
Downtown Key West, 11.7 km from Key West National Wildlife Refuge
United States
Cathrine
CA $225
CA $283 total
includes taxes & fees
Oct 26 - Oct 27
Duval House
A room with a door featuring horizontal blinds, a visible outdoor view through the window, and a patterned carpet.
A garden with a stone pathway, a wooden fence, and various tropical plants.
A pool area with a circular pool, lounge chairs, and a gazebo.
A room with a bed, a desk, a chair, a lamp, a painting of a boat on water, and a view of the sea.

12. Alexander Palms Court

Alexander Palms Court
Casa Marina, 12.4 km from Key West National Wildlife Refuge
United States
Brenda
CA $291
CA $328 total
includes taxes & fees
Oct 20 - Oct 21
Alexander Palms Court
A two-story building with a covered entrance, palm trees, and a bench outside.
A white picket fence, a wooden bench with cushions, and a concrete pathway surrounded by lush greenery.
A bright room with a staircase, two windows overlooking a pool area, and two wicker chairs with cushions.
A poolside area with lounge chairs, umbrellas, and a covered seating area with hanging lights.

13. Winslow's Bungalows - Key West Historic Inns

Winslow's Bungalows - Key West Historic Inns
Old Town Key West, 12.1 km from Key West National Wildlife Refuge
United States
Elizabeth
CA $283
CA $390 total
includes taxes & fees
Oct 25 - Oct 26
Winslow's Bungalows - Key West Historic Inns
A pool area with lounge chairs and a table, surrounded by palm trees.
A hotel room with a large bed, a nightstand, a desk, a bathroom with a shower, and a painting of a pier over water on the wall.
A building with a neon sign that reads "Orchid Key Inn."
A patio with a white wicker lounge chair, a wooden table with a book and a potted plant, surrounded by lush tropical foliage and palm trees.

14. Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
Uptown - Upper Duval, 11.8 km from Key West National Wildlife Refuge
United States
ben
CA $349
CA $392 total
includes taxes & fees
Oct 26 - Oct 27
Orchid Key Inn - Adults Only
A deck with sun loungers and a railing overlooking the sea.
A poolside area with lounge chairs and umbrellas, palm trees, and a view of the sea.
A beach scene with two people relaxing under a white umbrella, a palm tree, and a clear blue sky.
A beachside hotel with rows of blue lounge chairs and white umbrellas, palm trees, and a clear blue sky.

15. Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
Uptown - Upper Duval, 12.1 km from Key West National Wildlife Refuge
United States
Jacob Stuart
CA $246
CA $381 total
includes taxes & fees
Oct 25 - Oct 26
Southernmost Beach Resort and Guesthouses
A wooden deck with a hammock, pool, and lounge chairs overlooking a tropical garden.
A pool area with lounge chairs and a wooden building with balconies.
A garden with a pond, rocks, and various plants.
A compact kitchen with wooden cabinets, a microwave, stove, and refrigerator. There is a dining area with a table and chairs, and a sofa.

16. Island City House Hotel

Island City House Hotel
Historic Seaport, 11.7 km from Key West National Wildlife Refuge
United States
Elise
CA $266
CA $299 total
includes taxes & fees
Oct 27 - Oct 28
Island City House Hotel
Lobby
Room
A two-story building with a balcony, a flag, and a palm tree.
A covered outdoor area with a pool, wicker furniture, and a red umbrella.

17. The Independent Inn-Adults only

The Independent Inn-Adults only
Historic Seaport, 12.1 km from Key West National Wildlife Refuge
United States
Michael
CA $207
CA $281 total
includes taxes & fees
Oct 28 - Oct 29
The Independent Inn-Adults only
A bedroom with a bed, bedside table, lamp, and a small kitchenette. There is a balcony with wicker chairs and a glass table.
A pool area with lounge chairs and umbrellas, surrounded by buildings with balconies and a clear blue sky.
A spacious living area with a gray sofa, wooden staircase, and a kitchen in the background.
A cozy cabin with a wooden interior, a bed, a TV, and a kitchenette.

18. Eden House

Eden House
Historic Seaport, 12 km from Key West National Wildlife Refuge
United States
Michelle
CA $216
CA $272 total
includes taxes & fees
Oct 28 - Oct 29
Eden House
A modern hotel room with a white sofa, a zebra-patterned rug, and a large mirror above the sofa.
A pool area with lounge chairs, a pool, and a building with a balcony and outdoor seating.
A spacious living room with a sofa, chairs, and a dining table. There are large windows with blinds, a door leading to a patio, and a ceiling with exposed beams.
A narrow room with a bed, a potted plant, and a window with blinds.

19. Alexander's Guesthouse - Adult Exclusive

Alexander's Guesthouse - Adult Exclusive
Old Town Key West, 12.2 km from Key West National Wildlife Refuge
United States
Nestor
CA $228
CA $312 total
includes taxes & fees
Oct 20 - Oct 21
Alexander's Guesthouse - Adult Exclusive
A bottle of Marc's Reserve 12 FL. OZ. on a coaster with a metal table.
A pool with a lion head sculpture in the center.
A patio area with white metal tables and chairs, surrounded by potted plants and palm trees.
A front door with purple shutters, a small porch, and a doormat with 'The Artist House Circa 1890' text.

20. Artist House Key West

Artist House Key West
Historic Seaport, 11.4 km from Key West National Wildlife Refuge
United States
Debbie
CA $281
CA $316 total
includes taxes & fees
Oct 29 - Oct 30
Artist House Key West
View all properties

Compare popular hotels close to Key West National Wildlife Refuge

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A wooden archway leading to a pool area surrounded by lush tropical vegetation.
Parrot Key Hotel & Villas
9.0
Wonderful
1,481 reviews
View
A wooden deck with wicker furniture and a glass balustrade overlooking a beach.
Casa Marina Key West, Curio Collection by Hilton
8.4
Very good
979 reviews
View
A tropical outdoor area with palm trees, hanging plants, and string lights.
Douglas House - Adults Only
9.8
Exceptional
560 reviews
View
A large, ornate hotel with a pool, palm trees, and a view of the ocean.
Southernmost House - Adult Exclusive
9.4
Exceptional
1,002 reviews
View
A pool area with lounge chairs and palm trees.
Santa Maria Suites
9.6
Exceptional
1,003 reviews
View

Hotels recommended for families near Key West National Wildlife Refuge

A pool area with lounge chairs and a cabana.
A balcony with a table set for breakfast, overlooking the sea.
A dining area with a glass table, clear glass bottles, a bowl of fruit, and a wicker chair.
A hotel room with a bed, a sofa, a desk with a computer, a chair, and a view of the sea through large windows.

Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
Key West Historic District
CA $423
CA $590 total
includes taxes & fees
Oct 20 - Oct 21
Ocean Key Resort - A Noble House Resort
A beachfront hotel with a covered patio, palm trees, and a boat on the sand.
A resort with a beach, a dock, and a water view.
A view through a white-framed window with a decorative white fence, leading to a tiled patio area with a round table.
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a building with balconies.

Pier House Resort & Spa

Pier House Resort & Spa
Key West Historic District
CA $379
CA $525 total
includes taxes & fees
Nov 18 - Nov 19
Pier House Resort & Spa
A hotel with a swimming pool, balconies, and a view of the sea.
A spacious bar area with a wooden counter and green bar stools, a seating area with a sofa and chairs, and a dining area with a table set for two.
A marina with jet skis docked in front of a hotel with a dock and a boat in the background.
A balcony with a view of the ocean, a table, chairs, and a railing.

Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
Key West Historic District
CA $355
CA $498 total
includes taxes & fees
Oct 26 - Oct 27
Hyatt Centric Key West Resort and Spa
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a building with a white facade.
A bedroom with a sloped ceiling, a bed, two chairs, a hanging light fixture, and a window with a view of greenery.
A modern kitchen with a wooden counter, two stools, a wicker chair, and a hanging light fixture.
A pathway leading to a white gazebo with a view of a lighthouse in the distance.

Lighthouse Hotel - Key West Historic Inns

Lighthouse Hotel - Key West Historic Inns
Old Town Key West
CA $283
CA $390 total
includes taxes & fees
Oct 20 - Oct 21
Lighthouse Hotel - Key West Historic Inns
A white building with green shutters and a white picket fence.
A brick pathway leading to a green door, surrounded by lush tropical plants and a white fence.
A hotel room with a large bed, a sitting area, and multiple bookshelves filled with books.
A modern kitchen with white cabinetry, a central island, and a view of the outdoors.

Ridley House - Key West Historic Inns

Ridley House - Key West Historic Inns
Key West Historic District
CA $283
CA $390 total
includes taxes & fees
Oct 25 - Oct 26
Ridley House - Key West Historic Inns
A poolside area with lounge chairs, umbrellas, and a pergola.
A wooden bench with a cushion and a small table, surrounded by bamboo plants and a wooden deck.
A bright kitchen with white cabinetry, a white island, wicker pendant lights, and geometric patterned backsplash.
A living room with a spiral staircase, a sofa, a chair, a coffee table, and a view of an outdoor seating area.

Ella's Cottages - Key West Historic Inns

Ella's Cottages - Key West Historic Inns
Old Town Key West
CA $325
CA $437 total
includes taxes & fees
Oct 28 - Oct 29
Ella's Cottages - Key West Historic Inns
A large, white, two-story building with a balcony and a sign reading "The Marker Resort."
A covered outdoor area with a pool, palm trees, and lounge chairs.
A resort with a swimming pool, lounge chairs, umbrellas, and palm trees.
A marina with various boats docked, including a green and white boat named 'Jolly Roger'.

The Marker Key West Harbor Resort

The Marker Key West Harbor Resort
Key West Historic District
CA $266
CA $389 total
includes taxes & fees
Oct 25 - Oct 26
The Marker Key West Harbor Resort
A two-story building with a covered entrance, palm trees, and a bench outside.
A white picket fence, a wooden bench with cushions, and a concrete pathway surrounded by lush greenery.
A bright room with a staircase, two windows overlooking a pool area, and two wicker chairs with cushions.
A poolside area with lounge chairs, umbrellas, and a covered seating area with hanging lights.

Winslow's Bungalows - Key West Historic Inns

Winslow's Bungalows - Key West Historic Inns
Old Town Key West
CA $283
CA $390 total
includes taxes & fees
Oct 25 - Oct 26
Winslow's Bungalows - Key West Historic Inns

Top Key West National Wildlife Refuge Hotel Reviews

Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

10/10 Excellent
"Excellent all around."
Harvey 3-night trip
Posted 1 hour ago
Hyatt Centric Key West Resort and Spa
The Marker Key West Harbor Resort

The Marker Key West Harbor Resort

10/10 Excellent
"The Marker Resort. This place is one of the best places to stay in Key West! Great Location to everything we like to do. One of the swimming pools were closed for the week but highly recommend this resort."
Bob 4-night trip
Posted 7 hours ago
The Marker Key West Harbor Resort
The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

10/10 Excellent
"Booked here last minute due to our Vrbo being canceled - Can't say enough nice things about it! - Yes, the rooms are very small and the hallways are a bit older but this place is gorgeous! Pools are excellent and the staff is too. Only thing is if you like breakfast, go out. It's bland and boring at best."
Timothy 2-night trip
Posted 9 hours ago
The Southernmost Inn - Adults Only
Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West

10/10 Excellent
"Great hotel will definitely stay again"
Ann 2-night trip
Posted 11 hours ago
Opal Key Resort & Marina, Key West
Tranquility Guest House

Tranquility Guest House

10/10 Excellent
"Tranquility is just that. Quiet except for local roosters, safe, peaceful and private. There’s no front desk but the manager was in touch and checked in frequently. Great neighborhood nestled between Duval and the state park with fabulous beach."
Carol 4-night trip
Posted 21 hours ago
Tranquility Guest House
Pier House Resort & Spa

Pier House Resort & Spa

10/10 Excellent
"Everything was exceptional at Pier House. Breakfast by the water every morning great music and drinks from the bar, well maintained property and beach! Staff went out of their way and were very kimd. Our room with lanai was fantastic! Thank you Pier House!"
Steven 3-night trip
Posted 1 day ago
Pier House Resort & Spa
Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort

10/10 Excellent
"We had a great time! Location is great! Staff were wonderful!"
Jeremy 4-night trip
Posted 1 day ago
Ocean Key Resort - A Noble House Resort
Weatherstation Inn

Weatherstation Inn

10/10 Excellent
"Our stay was for two nights in October 2026. This is a beautiful property in a wonderful neighborhood, the Truman Annex section of Key West. The hotel is historic, quite classic, with property filled with tropical plantings, all well maintained. The staff was so friendly, professional, polite and very helpful. Our room was spotless and nicely appointed, with extra thoughtful touches...cozy terry robes, and slippers. Bathroom was lovely, large and cheery. Additional cotton blankets and beach towels were so nice to have on hand. The self-serve breakfast included an assortment of croissant pastries and doughnuts, yogurt, fresh fruit and of course coffee, including hot chocolate and various teas. So delicious! The pool area is charming. Bicycles for rent were just inside the gate. The location couldn't be better. Quiet yet so close to everything. We love staying at historic properties. The Weatherstation Inn did not disappoint! We will definitely be back again. One more thing! Parking is included on property."
Cheryl 1-night trip
Posted 2 days ago
Weatherstation Inn
La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection

10/10 Excellent
"Loved our stay at La Concha. Staff was excellent and constantly focused on our comfort and enjoyment. Upon arrival (kind of late), we were unsure if the bar was still serving food. Once staff became aware that we wanted food, they did everything they could think of to ensure we got what we needed. Top-notch customer service! The location of the hotel could not be beat, for our purposes. Easy to explore many different areas that we wanted to see…particularly Old Town and the seaport district. Everything is very walkable; however, if you have people in your party who cannot walk much distance, it is very easy to rent a golf cart to haul them around. An extremely enjoyable trip, made all the better by the staff and quality of La Concha."
LEE 7-night trip
Posted 3 days ago
La Concha Key West, Autograph Collection

Other attractions near Key West National Wildlife Refuge

A wooden signpost with directional arrows pointing to various cities and their distances.
Photo by Martin Pettersson

Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.
See properties
A coastal fortification with a staircase leading to a higher platform, overlooking the sea.

Fort Zachary Taylor Historic State Park

9.0/10 (4,544 reviews)
The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.
See properties
A sign reading "Welcome to Mallory Square" with an American flag, a red and white striped awning, and a statue of a man in a blue shirt and straw hat.

Mallory Square

9.2/10 (15,939 reviews)
Arrive at this square at day’s end to find street performers, food carts and one of the most beautiful sunsets in the United States.
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A historic building with a tall tower, palm trees, and a vintage trolley.

Key West Shipwreck Museum

8.6/10 (361 reviews)
This interactive museum is home to unbelievable relics pulled from the bottom of the sea and a watchtower with views across the Gulf of Mexico.
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Coffee Butler Amphitheater

You can enjoy a show at Coffee Butler Amphitheater during your trip to Key West. Discover the area's lively bars and its entertainment choices.
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USCGC Ingham Maritime Museum

You can spend an afternoon exploring the galleries in USCGC Ingham Maritime Museum during your trip to Key West.
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Florida Keys National Marine Sanctuary

9.0/10 (112 reviews)
Enjoy a trip to Florida Keys National Marine Sanctuary and popular activities like boating in Key West. In the area, take in the lively festivals and beautiful sunsets.
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Waterfront Playhouse

8.4/10 (7 reviews)
You can enjoy a show at Waterfront Playhouse during your trip to Key West. Wander the seaside and beautiful beaches in the area.
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Frequently asked questions

What's the area like around Key West National Wildlife Refuge?
Key West National Wildlife Refuge is located in an area of Key West known for its bar scene, biking, and lively festivals. Key West is home to 2618 hotels and other accommodations, so you can find something that's perfect for your stay.
What's the best place to stay close to Key West National Wildlife Refuge?
Pier House Resort & Spa is one of the top choices for your stay based on our traveler data, and this resort offers a full-service spa and a private beach. You'll find it 6.9 mi (11 km) from Key West National Wildlife Refuge. Other good options around the area include Hyatt Centric Key West Resort and Spa and La Concha Key West, Autograph Collection.
If I need to cancel the hotel reservation for my stay near Key West National Wildlife Refuge, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best options available near Key West National Wildlife Refuge.

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