Title: Book The Best Hotels in Isola, MS for 2026 from CA $98 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Isola](https://expedia.ca/Isola-Vacation-Rentals.d553248635975852319.Travel-Guide-VacationRentals)[Isola Car Rentals](https://expedia.ca/Car-Rentals-In-Isola.d553248635975852319.Car-Rental-Guide)[Isola Vacation Packages](https://expedia.ca/Isola.d553248635975852319.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Isola, MS from CA $98 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Isola Resort [](https://www.expedia.ca/Hotel-Search?destination=Isola%2C+Mississippi%2C+United+States+of+America®ionId=553248635975852319&latLong=33.262066%2C-90.592314&adults=2&startDate=2025-12-24&d1=2025-12-24&endDate=2025-12-26&d2=2025-12-26&lodging=HOTEL_RESORT) Spa [](https://www.expedia.ca/Hotel-Search?destination=Isola%2C+Mississippi%2C+United+States+of+America®ionId=553248635975852319&latLong=33.262066%2C-90.592314&adults=2&startDate=2025-12-24&d1=2025-12-24&endDate=2025-12-26&d2=2025-12-26&amenities=SPA_ON_SITE) Apart hotel [](https://www.expedia.ca/Hotel-Search?destination=Isola%2C+Mississippi%2C+United+States+of+America®ionId=553248635975852319&latLong=33.262066%2C-90.592314&adults=2&startDate=2025-12-24&d1=2025-12-24&endDate=2025-12-26&d2=2025-12-26&lodging=APART_HOTEL) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Isola%2C+Mississippi%2C+United+States+of+America®ionId=553248635975852319&latLong=33.262066%2C-90.592314&adults=2&startDate=2025-12-24&d1=2025-12-24&endDate=2025-12-26&d2=2025-12-26&travelerType=family_friendly) Ryokan [](https://www.expedia.ca/Hotel-Search?destination=Isola%2C+Mississippi%2C+United+States+of+America®ionId=553248635975852319&latLong=33.262066%2C-90.592314&adults=2&startDate=2025-12-24&d1=2025-12-24&endDate=2025-12-26&d2=2025-12-26&lodging=RYOKAN) Ocean view [](https://www.expedia.ca/Hotel-Search?destination=Isola%2C+Mississippi%2C+United+States+of+America®ionId=553248635975852319&latLong=33.262066%2C-90.592314&adults=2&startDate=2025-12-24&d1=2025-12-24&endDate=2025-12-26&d2=2025-12-26&amenities=OCEAN_VIEW) Cabin [](https://www.expedia.ca/Hotel-Search?destination=Isola%2C+Mississippi%2C+United+States+of+America®ionId=553248635975852319&latLong=33.262066%2C-90.592314&adults=2&startDate=2025-12-24&d1=2025-12-24&endDate=2025-12-26&d2=2025-12-26&lodging=CABIN) Farm [](https://www.expedia.ca/Hotel-Search?destination=Isola%2C+Mississippi%2C+United+States+of+America®ionId=553248635975852319&latLong=33.262066%2C-90.592314&adults=2&startDate=2025-12-24&d1=2025-12-24&endDate=2025-12-26&d2=2025-12-26&lodging=AGRITOURISM) Capsule hotel [](https://www.expedia.ca/Hotel-Search?destination=Isola%2C+Mississippi%2C+United+States+of+America®ionId=553248635975852319&latLong=33.262066%2C-90.592314&adults=2&startDate=2025-12-24&d1=2025-12-24&endDate=2025-12-26&d2=2025-12-26&lodging=CAPSULE_HOTEL) Pool [](https://www.expedia.ca/Hotel-Search?destination=Isola%2C+Mississippi%2C+United+States+of+America®ionId=553248635975852319&latLong=33.262066%2C-90.592314&adults=2&startDate=2025-12-24&d1=2025-12-24&endDate=2025-12-26&d2=2025-12-26&amenities=POOL) Castle [](https://www.expedia.ca/Hotel-Search?destination=Isola%2C+Mississippi%2C+United+States+of+America®ionId=553248635975852319&latLong=33.262066%2C-90.592314&adults=2&startDate=2025-12-24&d1=2025-12-24&endDate=2025-12-26&d2=2025-12-26&lodging=CASTLE) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Isola%2C+Mississippi%2C+United+States+of+America®ionId=553248635975852319&latLong=33.262066%2C-90.592314&adults=2&startDate=2025-12-24&d1=2025-12-24&endDate=2025-12-26&d2=2025-12-26&amenities=HOT_TUB) ## Check prices for these dates Tonight [Dec 10 - Dec 11](https://www.expedia.ca/Hotel-Search?regionId=553248635975852319&startDate=2025-12-10&endDate=2025-12-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 11 - Dec 12](https://www.expedia.ca/Hotel-Search?regionId=553248635975852319&startDate=2025-12-11&endDate=2025-12-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635975852319&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635975852319&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Isola hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/220000/214900/214874/612835dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/220000/214900/214874/85ea5324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/220000/214900/214874/4fc87000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/220000/214900/214874/d0861369.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Indianola [](https://www.expedia.ca/Greenville-Hotels-Super-8-By-Wyndham-Indianola.h214874.Hotel-Information) Indianola 7.2/10 Good (375) "Room was clean and comfortable" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Michael Traveling solo CA $125 CA $136 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Greenville-Hotels-Super-8-By-Wyndham-Indianola.h214874.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4155/06b27a0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/4200/4155/3c152f39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/10000/4200/4155/837d71c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4155/f7185eca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Indianola [](https://www.expedia.ca/Greenville-Hotels-Quality-Inn.h4155.Hotel-Information) Indianola 7.2/10 Good (122) "Worst hotel I ever stayed in, tub was black as the ground, we could not take a shower, the carpet reeked of mildew, your hotel should be shut down and closed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charlotte CA $100 CA $109 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/Greenville-Hotels-Quality-Inn.h4155.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/10000/10000/9942/c3551096.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, towels](https://images.trvl-media.com/lodging/1000000/10000/10000/9942/35cd0489.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/10000/10000/9942/b87296b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/10000/9942/f628a77d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Indianola [](https://www.expedia.ca/Greenville-Hotels-Americas-Best-Value-Inn-Indianola.h9942.Hotel-Information) Indianola 7.4/10 Good (201) "Very clean room and bathroom." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dean Traveling for leisure CA $90 CA $98 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Greenville-Hotels-Americas-Best-Value-Inn-Indianola.h9942.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-24&endDate=2025-12-25®ionId=553248635975852319&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FIsola-Hotels.d553248635975852319.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FIsola-Hotels.d553248635975852319.Travel-Guide-Hotels) ## More cheap stays in Isola ![Americas Best Value Inn Indianola](https://images.trvl-media.com/lodging/1000000/10000/10000/9942/c3551096_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Americas Best Value Inn Indianola 1015 Highway 82 E Indianola MS CA $90 CA $98 total Dec 11 - Dec 12 includes taxes & fees 7.4/10 Good! (201 reviews) [](https://expedia.ca/Greenville-Hotels-Americas-Best-Value-Inn-Indianola.h9942.Hotel-Information) ![Quality Inn Indianola](https://images.trvl-media.com/lodging/1000000/10000/4200/4155/06b27a0b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Indianola 910 Highway 82 E Indianola MS CA $100 CA $109 total Dec 24 - Dec 25 includes taxes & fees 7/10 Good! (122 reviews) [](https://expedia.ca/Greenville-Hotels-Quality-Inn.h4155.Hotel-Information) ![Super 8 by Wyndham Indianola](https://images.trvl-media.com/lodging/1000000/220000/214900/214874/612835dd_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Indianola 601 Highway 82 W Indianola MS CA $125 CA $136 total Dec 11 - Dec 12 includes taxes & fees 7.2/10 Good! (375 reviews) [](https://expedia.ca/Greenville-Hotels-Super-8-By-Wyndham-Indianola.h214874.Hotel-Information) ![Hampton Inn Indianola MS](https://images.trvl-media.com/lodging/14000000/13150000/13144800/13144705/997f0516_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Indianola MS 913 Highway 82 West Indianola MS [Get rates](https://expedia.ca/Hotel-Search?startDate=24%2F12%2F2025&endDate=25%2F12%2F2025&selected=13144705&PinnedHotelID=13144705&HadPinnedHotel=true®ionId=553248635975852319) [](https://expedia.ca/Indianola-Hotels-Hampton-Inn-Indianola-MS.h13144705.Hotel-Information) ## Hotels in Isola with star-rating ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 4 properties [](https://expedia.ca/2Star-Isola-Hotels.s20-0-d553248635975852319.Travel-Guide-Filter-Hotels) ## Recent reviews of Isola hotels ![Super 8 by Wyndham Indianola](https://images.trvl-media.com/lodging/1000000/220000/214900/214874/612835dd_y.jpg) ### Super 8 by Wyndham Indianola 5/5 Excellent "Courtasy of staff" A verified traveller stayed at Super 8 by Wyndham Indianola Posted 8 days ago [](https://expedia.ca/Greenville-Hotels-Super-8-By-Wyndham-Indianola.h214874.Hotel-Information) ![Americas Best Value Inn Indianola](https://images.trvl-media.com/lodging/1000000/10000/10000/9942/c3551096_y.jpg) ### Americas Best Value Inn Indianola 5/5 Excellent "Very clean room and bathroom. Very comfortable bed. My travel plans changed by a day, and although Expedia wouldn’t let me change the day, the hotel changed it when I called them a couple days early. I travelled by motorcycle and they also changed my room to the ground floor when I arrived so I could park my motorcycle right outside my door." A verified traveller stayed at Americas Best Value Inn Indianola Posted 1 month ago [](https://expedia.ca/Greenville-Hotels-Americas-Best-Value-Inn-Indianola.h9942.Hotel-Information) ![Quality Inn Indianola](https://images.trvl-media.com/lodging/1000000/10000/4200/4155/06b27a0b_y.jpg) ### Quality Inn Indianola 4/5 Good "The ladies at the front desk were very nice and welcoming." A verified traveller stayed at Quality Inn Indianola Posted 2 months ago [](https://expedia.ca/Greenville-Hotels-Quality-Inn.h4155.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Isola? > This neighbourhood is the primary spot for visitors. It's quite walkable and features the majority of Isola's local businesses, including shops and eateries. The general layout is straightforward, with attractions typically found along or just off Main Street. > > > For solo travellers or couples, this area is ideal for experiencing the local community. You'll find it convenient for accessing local events and getting a feel for the town's character. > > > Travellers looking for a quiet stay will appreciate the relaxed pace of Isola. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Isola hotel booking with Expedia? ### How much is the nightly rate at a Isola hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Luxury Hotels in Anguilla ](https://www.expedia.ca/Anguilla-Hotels-Luxury-Hotel.0-0-d553248635125972568-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Anguilla Hotels ](https://www.expedia.ca/Anguilla-Hotels.d553248635125972568.Travel-Guide-Hotels) - [Cheap Hotels in Belzoni ](https://www.expedia.ca/Belzoni-Hotels-Cheap-Hotels.0-0-d3000444033-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Belzoni ](https://www.expedia.ca/Belzoni-Hotels-Luxury-Hotel.0-0-d3000444033-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Belzoni Hotels ](https://www.expedia.ca/Belzoni-Hotels.d3000444033.Travel-Guide-Hotels) - 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