Title: Best Hotels Near Greenville Hospital System, Simpsonville from CA $85 | Expedia.ca

[Simpsonville Travel Guide](https://expedia.ca/Simpsonville.dx6239)[Vacation Rentals in Simpsonville](https://expedia.ca/Simpsonville-Vacation-Rentals.d6239.Travel-Guide-VacationRentals)[Flights to Simpsonville](https://expedia.ca/Cheap-Flights-To-Simpsonville.d6239.Travel-Guide-Flights)[Greenville Hospital System Car Rentals](https://expedia.ca/Car-Rentals-In-Greenville-Hospital-System.d911211487220301824.Car-Rental-Guide)[Greenville Hospital System Vacations](https://expedia.ca/Greenville-Hospital-System-Simpsonville.d911211487220301824.Vacation-Attraction)

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## Check prices for these dates

Tonight

[Feb 11 - Feb 12](https://www.expedia.ca/Hotel-Search?regionId=911211487220301824&startDate=2026-02-11&endDate=2026-02-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 12 - Feb 13](https://www.expedia.ca/Hotel-Search?regionId=911211487220301824&startDate=2026-02-12&endDate=2026-02-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=911211487220301824&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=911211487220301824&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Greenville Hospital System hotels

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/5cc3b6ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/51a7c4d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/95c63f23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/42b56840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Greenville Simpsonville

[](https://www.expedia.ca/Simpsonville-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville-Simpsonville.h119074.Hotel-Information)

0.9 km from Greenville Hospital System

9.2/10

Wonderful

(679 reviews)

"Quick check in, and the rooms were clean!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

DENNIS

CA $137

CA $151 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Simpsonville-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville-Simpsonville.h119074.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/130000/120500/120431/a7e2d124.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/1000000/130000/120500/120431/39e12856.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/1000000/130000/120500/120431/a826354f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Minibar](https://images.trvl-media.com/lodging/1000000/130000/120500/120431/1c93baf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Simpsonville

[](https://www.expedia.ca/Simpsonville-Hotels-Hampton-Inn-Simpsonville.h120431.Hotel-Information)

0.7 km from Greenville Hospital System

8.8/10

Excellent

(608 reviews)

"Everything was good"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Courtney

CA $145

CA $170 total

includes taxes & fees

Feb 26 - Feb 27

[](https://www.expedia.ca/Simpsonville-Hotels-Hampton-Inn-Simpsonville.h120431.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/19000000/18990000/18989600/18989520/18e8e500.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/19000000/18990000/18989600/18989520/b9fd26fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/19000000/18990000/18989600/18989520/c06326d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18990000/18989600/18989520/64221897.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG

[](https://www.expedia.ca/Simpsonville-Hotels-Holiday-Inn-Express-Suites-Greenville-SE-Simpsonville.h18989520.Hotel-Information)

1.3 km from Greenville Hospital System

9.4/10

Exceptional

(517 reviews)

"Friendly staff and everything was well kept."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ronny

CA $173

CA $191 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Simpsonville-Hotels-Holiday-Inn-Express-Suites-Greenville-SE-Simpsonville.h18989520.Hotel-Information)

![Suite, Non Smoking](https://images.trvl-media.com/lodging/3000000/2990000/2986100/2986074/a3ff3e5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2990000/2986100/2986074/ee72685c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2990000/2986100/2986074/b0c859da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/3000000/2990000/2986100/2986074/772de931.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Suites Simpsonville - Greenville

[](https://www.expedia.ca/Simpsonville-Hotels-Comfort-Suites-Simpsonville.h2986074.Hotel-Information)

1.5 km from Greenville Hospital System

8.2/10

Very good

(789 reviews)

"Wonderful stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Barrie

CA $110

CA $121 total

includes taxes & fees

Feb 20 - Feb 21

[](https://www.expedia.ca/Simpsonville-Hotels-Comfort-Suites-Simpsonville.h2986074.Hotel-Information)

![Room, 2 Queen Beds, Non Smoking (Upgrade)](https://images.trvl-media.com/lodging/1000000/30000/24900/24842/8683611a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Non Smoking (Upgrade)](https://images.trvl-media.com/lodging/1000000/30000/24900/24842/96d12f53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Non Smoking (Upgrade)](https://images.trvl-media.com/lodging/1000000/30000/24900/24842/w2868h1920x0y0-e40e27dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Non Smoking (Upgrade)](https://images.trvl-media.com/lodging/1000000/30000/24900/24842/9ddc6b2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Simpsonville - Greenville

[](https://www.expedia.ca/Simpsonville-Hotels-Quality-Inn-Simpsonville-Greenville.h24842.Hotel-Information)

0.8 km from Greenville Hospital System

7.4/10

Good

(170 reviews)

"Clean, quiet very comfortable "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Kathryn

CA $84

CA $97 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Simpsonville-Hotels-Quality-Inn-Simpsonville-Greenville.h24842.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/1000000/330000/328900/328810/d48e45aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/1000000/330000/328900/328810/0200d1b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/330000/328900/328810/8695f35e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/1000000/330000/328900/328810/4f8ad01e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 Simpsonville, SC - Greenville

[](https://www.expedia.ca/Simpsonville-Hotels-Motel-6-Simpsonville.h328810.Hotel-Information)

0.9 km from Greenville Hospital System

7.4/10

Good

(361 reviews)

"Very clean and nice staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

CA $95

CA $104 total

includes taxes & fees

Feb 12 - Feb 13

[](https://www.expedia.ca/Simpsonville-Hotels-Motel-6-Simpsonville.h328810.Hotel-Information)

![Desk, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/540000/533900/533881/0570b9fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/540000/533900/533881/136fac21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/540000/533900/533881/e4cbaa99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/540000/533900/533881/d8c4bcc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham Simpsonville

[](https://www.expedia.ca/Simpsonville-Hotels-Days-Inn-By-Wyndham-Simpsonville.h533881.Hotel-Information)

0.8 km from Greenville Hospital System

7.0/10

Good

(426 reviews)

"Breakfast was limited, rooms were ok, staff okay and nice. Bed had a smoke hole in the sheets. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rudes

CA $99

CA $109 total

includes taxes & fees

Feb 13 - Feb 14

[](https://www.expedia.ca/Simpsonville-Hotels-Days-Inn-By-Wyndham-Simpsonville.h533881.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/3000000/2430000/2429100/2429082/d1678ae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Vending machine](https://images.trvl-media.com/lodging/3000000/2430000/2429100/2429082/719100f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2430000/2429100/2429082/e4c62306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/3000000/2430000/2429100/2429082/57fd9745.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### WoodSpring Suites Greenville Simpsonville

[](https://www.expedia.ca/Simpsonville-Hotels-WoodSpring-Suites-Greenville-Simpsonville.h2429082.Hotel-Information)

2.8 km from Greenville Hospital System

6.8/10

(171 reviews)

"Staff is friendly but they have roaches and the whole place smells of marijuana and people are making noise all day and night. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jason

CA $84

CA $92 total

includes taxes & fees

Feb 12 - Feb 13

[](https://www.expedia.ca/Simpsonville-Hotels-WoodSpring-Suites-Greenville-Simpsonville.h2429082.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1640000/1635900/1635865/06cd3bc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed, Non Smoking | Private kitchen](https://images.trvl-media.com/lodging/2000000/1640000/1635900/1635865/913258c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/2000000/1640000/1635900/1635865/827bbd42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/2000000/1640000/1635900/1635865/64d0967f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### WoodSpring Suites Greenville Central I-85

[](https://www.expedia.ca/Greenville-Hotels-WoodSpring-Suites-Greenville-Central-I-85.h1635865.Hotel-Information)

14.4 km from Greenville Hospital System

6.6/10

(165 reviews)

"Kitchen is perfect"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

lenard

CA $88

CA $97 total

includes taxes & fees

Feb 12 - Feb 13

[](https://www.expedia.ca/Greenville-Hotels-WoodSpring-Suites-Greenville-Central-I-85.h1635865.Hotel-Information)

![Studio, 2 Double Beds, Non Smoking | View from room](https://images.trvl-media.com/lodging/105000000/104030000/104026100/104026045/a1bafc10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/105000000/104030000/104026100/104026045/w8234h5504x0y0-b7cca183.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/105000000/104030000/104026100/104026045/5b5763de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/105000000/104030000/104026100/104026045/ed90bd89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hometowne Studios Greenville

[](https://www.expedia.ca/Greenville-Hotels-Hometowne-Studios-Greenville.h104026045.Hotel-Information)

12.9 km from Greenville Hospital System

6.0/10

(5 reviews)

"Clean room, quiet"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Owen

CA $82

CA $91 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Greenville-Hotels-Hometowne-Studios-Greenville.h104026045.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/1000000/10000/3500/3451/8fa1c9bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Vending machine](https://images.trvl-media.com/lodging/1000000/10000/3500/3451/d8c48855.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3500/3451/d189e27b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/3500/3451/7c797e5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Red Roof Inn Greenville

[](https://www.expedia.ca/Greenville-Hotels-Red-Roof-Inn-Greenville.h3451.Hotel-Information)

13 km from Greenville Hospital System

6.0/10

(999 reviews)

"Decent room. Staff was great. Thanks"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Randal

CA $80

CA $88 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Greenville-Hotels-Red-Roof-Inn-Greenville.h3451.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/96000000/95670000/95668200/95668169/a8a1fed9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/96000000/95670000/95668200/95668169/8de073a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exercise/lap pool](https://images.trvl-media.com/lodging/96000000/95670000/95668200/95668169/86c1e212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed](https://images.trvl-media.com/lodging/96000000/95670000/95668200/95668169/402009cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Greenville Inn and Suites

[](https://www.expedia.ca/Greenville-Hotels-1314-S-Pleasantburg-Dr.h95668169.Hotel-Information)

14.9 km from Greenville Hospital System

6.2/10

(186 reviews)

"It was a good stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Owen

[](https://www.expedia.ca/Greenville-Hotels-1314-S-Pleasantburg-Dr.h95668169.Hotel-Information)

![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1430000/1424600/1424543/15fdc684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/2000000/1430000/1424600/1424543/83c209be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/2000000/1430000/1424600/1424543/a01b711e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1430000/1424600/1424543/b52ddfee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Studio 6 Greenville, SC - I-85 Near Downtown

[](https://www.expedia.ca/Greenville-Hotels-Studio-6-Greenville.h1424543.Hotel-Information)

14.2 km from Greenville Hospital System

5.8/10

(85 reviews)

"Great customer service support "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Steven

CA $80

CA $88 total

includes taxes & fees

Feb 16 - Feb 17

[](https://www.expedia.ca/Greenville-Hotels-Studio-6-Greenville.h1424543.Hotel-Information)

![Room, 2 Queen Beds, Non Smoking (Third Floor)](https://images.trvl-media.com/lodging/1000000/30000/22300/22276/c4198629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/22300/22276/74b617df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/30000/22300/22276/f001df1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22300/22276/18799fc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham Greenville

[](https://www.expedia.ca/Greenville-Hotels-Days-Inn-By-Wyndham-Greenville.h22276.Hotel-Information)

14.4 km from Greenville Hospital System

5.6/10

(1,000 reviews)

"clean room great staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shelby

CA $83

CA $91 total

includes taxes & fees

Mar 3 - Mar 4

[](https://www.expedia.ca/Greenville-Hotels-Days-Inn-By-Wyndham-Greenville.h22276.Hotel-Information)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1040000/1037800/1037778/8c2e58f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Vending machine](https://images.trvl-media.com/lodging/2000000/1040000/1037800/1037778/w3456h2298x0y66-334bc378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1040000/1037800/1037778/5e1ca991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1040000/1037800/1037778/56c39c13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Budget Inn Greenville By Hotel O I-85 

[](https://www.expedia.ca/Greenville-Hotels-Econo-Lodge.h1037778.Hotel-Information)

14.9 km from Greenville Hospital System

5.0/10

(419 reviews)

"Good stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Victor

CA $73

CA $85 total

includes taxes & fees

Feb 16 - Feb 17

[](https://www.expedia.ca/Greenville-Hotels-Econo-Lodge.h1037778.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/59000000/58950000/58945900/58945857/3ff858d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/59000000/58950000/58945900/58945857/015cc42b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/59000000/58950000/58945900/58945857/561d946e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/59000000/58950000/58945900/58945857/5af30e15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Greenville Mauldin

[](https://www.expedia.ca/Greenville-Hotels-Courtyard-By-Marriott-Greenville-Mauldin.h58945857.Hotel-Information)

10 km from Greenville Hospital System

9.0/10

Wonderful

(314 reviews)

"The room was extremely clean, very spacious and the shower had amazing water pressure!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Manny

CA $148

CA $163 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Greenville-Hotels-Courtyard-By-Marriott-Greenville-Mauldin.h58945857.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/67700/67687/c970850a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/70000/67700/67687/fcb3419e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/70000/67700/67687/da866fd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/70000/67700/67687/ada26199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Greenville I-385 - Woodruff Rd.

[](https://www.expedia.ca/Greenville-Hotels-Hampton-Inn-Greenville-I-385-Woodruff-Rd.h67687.Hotel-Information)

12.1 km from Greenville Hospital System

8.8/10

Excellent

(797 reviews)

"Clean bathroom, spacious room."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gavin

CA $127

CA $144 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Greenville-Hotels-Hampton-Inn-Greenville-I-385-Woodruff-Rd.h67687.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/0007de95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/w1021h678x3y4-70d9704c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/f59bfe6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/074f4a70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DoubleTree by Hilton Greenville Woodruff Road

[](https://www.expedia.ca/Greenville-Hotels-DoubleTree-By-Hilton-Greenville-Woodruff-Road.h50828647.Hotel-Information)

12.6 km from Greenville Hospital System

9.4/10

Exceptional

(1,005 reviews)

"Room for was super clean! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kristina

CA $160

CA $176 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Greenville-Hotels-DoubleTree-By-Hilton-Greenville-Woodruff-Road.h50828647.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/2000000/1700000/1696000/1695973/511019a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/2000000/1700000/1696000/1695973/4f5de5d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1700000/1696000/1695973/4dcdf2be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1700000/1696000/1695973/84877501.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Staybridge Suites Greenville I-85 Woodruff Road by IHG

[](https://www.expedia.ca/Greenville-Hotels-Staybridge-Suites-Greenville-I-85-Woodruff-Road.h1695973.Hotel-Information)

12.3 km from Greenville Hospital System

9.2/10

Wonderful

(318 reviews)

"Wonderful hotel would definitely recommend. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

laura nejude

CA $222

CA $245 total

includes taxes & fees

Mar 8 - Mar 9

[](https://www.expedia.ca/Greenville-Hotels-Staybridge-Suites-Greenville-I-85-Woodruff-Road.h1695973.Hotel-Information)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/164da543.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/d205b99b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/5e60bd70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Greenville

[](https://www.expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information)

12.9 km from Greenville Hospital System

9.4/10

Exceptional

(1,000 reviews)

"Very clean, great breakfast, helpful staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mike

CA $150

CA $165 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-25&endDate=2026-02-26&regionId=911211487220301824&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Compare popular hotels close to Greenville Hospital System

| Property                                                                                                                                                                                                    | Star rating       | Guest rating              | Breakfast included | Pool | Spa | Pet-friendly | WiFi included |  |
| ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- |  |
| ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/5cc3b6ae.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Fairfield Inn & Suites by Marriott Greenville Simpsonville          | 3.0 star property | 9.2Wonderful679 reviews   | View               |      |     |              |               |  |
| ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/130000/120500/120431/a7e2d124.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hampton Inn Simpsonville                        | 2.5 star property | 8.8Excellent608 reviews   | View               |      |     |              |               |  |
| ![Exterior](https://images.trvl-media.com/lodging/19000000/18990000/18989600/18989520/18e8e500.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG | 2.5 star property | 9.4Exceptional517 reviews | View               |      |     |              |               |  |
| ![Suite, Non Smoking](https://images.trvl-media.com/lodging/3000000/2990000/2986100/2986074/a3ff3e5d.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Comfort Suites Simpsonville - Greenville                   | 2.5 star property | 8.2Very good789 reviews   | View               |      |     |              |               |  |
| ![Room, 2 Queen Beds, Non Smoking (Upgrade)](https://images.trvl-media.com/lodging/1000000/30000/24900/24842/8683611a.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Quality Inn Simpsonville - Greenville     | 2.5 star property | 7.4Good170 reviews        | View               |      |     |              |               |  |

## Top Greenville Hospital System Hotel Reviews

![Days Inn by Wyndham Simpsonville](https://images.trvl-media.com/lodging/1000000/540000/533900/533881/136fac21_y.jpg)

### Days Inn by Wyndham Simpsonville

8/10 Good

"My room was very clean. Staff courteous "

[](https://expedia.ca/Simpsonville-Hotels-Days-Inn-By-Wyndham-Simpsonville.h533881.Hotel-Information)

![Hampton Inn Simpsonville](https://images.trvl-media.com/lodging/1000000/130000/120500/120431/91f2c765_y.jpg)

### Hampton Inn Simpsonville

10/10 Excellent

"Everything was good"

[](https://expedia.ca/Simpsonville-Hotels-Hampton-Inn-Simpsonville.h120431.Hotel-Information)

![WoodSpring Suites Greenville Simpsonville](https://images.trvl-media.com/lodging/3000000/2430000/2429100/2429082/1a20d17a_y.jpg)

### WoodSpring Suites Greenville Simpsonville

10/10 Excellent

"All of the above stood out and more! Like being a part of family away from family. I'm so happy to be here, especially the way security is top priority! I feel secure with no worries about harm coming to me. My thanks to the staff for great teamwork! I appreciate you so much! 💖💯"

[](https://expedia.ca/Simpsonville-Hotels-WoodSpring-Suites-Greenville-Simpsonville.h2429082.Hotel-Information)

![Motel 6 Simpsonville, SC - Greenville](https://images.trvl-media.com/lodging/1000000/330000/328900/328810/085635e5_y.jpg)

### Motel 6 Simpsonville, SC - Greenville

10/10 Excellent

"Yes"

[](https://expedia.ca/Simpsonville-Hotels-Motel-6-Simpsonville.h328810.Hotel-Information)

![Private Suite in Downtown Simpsonville](https://images.trvl-media.com/lodging/30000000/29490000/29483500/29483484/1672b9e2_y.jpg)

### Private Suite in Downtown Simpsonville

10/10 Excellent

"Great little apartment on Main St. Clean, comfortable, and conveniently located. "

[](https://expedia.ca/Simpsonville-Hotels-Private-Suite-In-Downtown-Simpsonville.h29483484.Hotel-Information)

![Quality Inn Simpsonville - Greenville](https://images.trvl-media.com/lodging/1000000/30000/24900/24842/40d1bdf8_y.jpg)

### Quality Inn Simpsonville - Greenville

10/10 Excellent

"Clean room. Newly renovated. Great location "

[](https://expedia.ca/Simpsonville-Hotels-Quality-Inn-Simpsonville-Greenville.h24842.Hotel-Information)

![Fairfield Inn & Suites by Marriott Greenville Simpsonville](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/089fe955_y.jpg)

### Fairfield Inn & Suites by Marriott Greenville Simpsonville

10/10 Excellent

"Quick check in, and the rooms were clean!"

[](https://expedia.ca/Simpsonville-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville-Simpsonville.h119074.Hotel-Information)

![4 bedroom, family-friendly, Simpsonville

](https://images.trvl-media.com/lodging/101000000/100800000/100796400/100796347/f5ab3035_y.jpg)

### 4 bedroom, family-friendly, Simpsonville 

10/10 Excellent

"Very nice! Clean and welcoming!"

[](https://expedia.ca/Simpsonville-Hotels-4-Bedroom.h100796347.Hotel-Information)

![Comfort Suites Simpsonville - Greenville](https://images.trvl-media.com/lodging/3000000/2990000/2986100/2986074/4f89980b_y.jpg)

### Comfort Suites Simpsonville - Greenville

10/10 Excellent

"Clean room !"

[](https://expedia.ca/Simpsonville-Hotels-Comfort-Suites-Simpsonville.h2986074.Hotel-Information)

## Hotels near other Greenville Hospital System attractions

### Fairview Station

You can browse for the perfect souvenirs at Fairview Station during your trip to Simpsonville. Take in the live music and sunrises in the area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=911208591535742976)

### Piedmont Plaza

You can browse for the perfect souvenirs at Piedmont Plaza during your visit to Simpsonville. Experience the area's live music and theater scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=911208428182269952)

### Simpsonville Commons

You can do some window-shopping at Simpsonville Commons during your trip to Simpsonville. Take in the live music and sunrises in the area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=911208336660467712)

### Chancellor's The Commons

You can enjoy retail therapy at Chancellor's The Commons during your trip to Simpsonville. Experience the area's live music and theater scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=911210573312925696)

### Hillcrest Pointe

You can search for that perfect souvenir at Hillcrest Pointe during your trip to Simpsonville. Experience the area's live music and theater scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=911208564442636288)

### Regal Simpsonville

You can take time to visit Regal Simpsonville during your travels to Simpsonville. Experience the area's live music and theater scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=941654557782884352)

### Foxwood Recreation Area

Foxwood Recreation Area is just one of the places to see in Simpsonville, so why not enjoy the other things to explore during your travels? Experience the area's live music and theater scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=911209012786454528)

### Fairview Commons

You can search for that perfect souvenir at Fairview Commons during your trip to Simpsonville. Experience the area's live music and theater scene. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=911208609919361024)

## Frequently asked questions

### What's the area like around Greenville Hospital System?

### What's the best hotel to stay close to Greenville Hospital System?

### How many hotels will I be able to find near Greenville Hospital System?

### If I need to cancel the hotel reservation for my stay near Greenville Hospital System, will I receive a refund?

### What can I see and do near Greenville Hospital System?