Title: Hotels by America's Best Inns in Clemson | Expedia.ca [Clemson Travel Guide](https://expedia.ca/Clemson.dx6594)[Hotels in Clemson](https://expedia.ca/Clemson-Hotels.d6594.Travel-Guide-Hotels)[Vacation Rentals in Clemson](https://expedia.ca/Clemson-Vacation-Rentals.d6594.Travel-Guide-VacationRentals)[Flights to Clemson](https://expedia.ca/Cheap-Flights-To-Clemson.d6594.Travel-Guide-Flights)[Things to do in Clemson](https://expedia.ca/Things-To-Do-In-Clemson.d6594.Travel-Guide-Activities)[Clemson Car Rentals](https://expedia.ca/Car-Rentals-In-Clemson.d6594.Car-Rental-Guide)[Clemson Vacation Packages](https://expedia.ca/Clemson.d6594.Destination-Travel-Guides) ![Sunset on the Docks in Clemson, South Carolina; Shutterstock ID 1068665087; purchase_order: SP-1269 HA 2018 Batch 1; Order: ; client: ; other:](https://images.trvl-media.com/place/6594/3559af33-8fc4-4b07-8fe6-f8db466d3d41.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6594/3559af33-8fc4-4b07-8fe6-f8db466d3d41.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 13 - Jan 14](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2026-01-13&endDate=2026-01-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 14 - Jan 15](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2026-01-14&endDate=2026-01-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FClemson-Hotels-Americas-Best-Inns.0-0-d6594--bAmericasBestInns.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FClemson-Hotels-Americas-Best-Inns.0-0-d6594--bAmericasBestInns.Travel-Guide-Filter-Hotels) ## Top Clemson Hotel Reviews ![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "Beautiful hotel. Great service. Delicious food. " [](https://expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Holiday Inn Express & Suites Clemson by IHG](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558616/ff716430_y.jpg) ### Holiday Inn Express & Suites Clemson by IHG 10/10 Excellent "I just wanted to take this opportunity to acknowledge Tara, who was so helpful in helping me check out and providing overall great customer service, especially locating my customer rewards #. The staff is always great here and I appreciate the investment being made in the property to make it look so nice. Keep up the good work! I will continue to stay here whenever I need to visit my daughter in Clemson. " [](https://expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Suites-Clemson.h2558616.Hotel-Information) ![Comfort Inn & Suites Clemson - University Area](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/e51fff20_y.jpg) ### Comfort Inn & Suites Clemson - University Area 10/10 Excellent "Clean and convenient " [](https://expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Days Inn by Wyndham Anderson](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24_y.jpg) ### Days Inn by Wyndham Anderson 10/10 Excellent "Nice for price. Nice staff. " [](https://expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![The Inn at Patrick Square](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/959a330b_y.jpg) ### The Inn at Patrick Square 10/10 Excellent "Parking was easy and abundant. The hotel is located in a cute market square, with a pub, restaurant, pharmacy, and cryo iv center all within a block. The staff were very friendly, and happy to assist with our needs. Our only problem was the lack of microwave in room, and the limited choices in their snack area. There is a cafe attached to the hotel. The staff were friendly, but it did not offer simple black tea, everything was herbal organic, and their hours were very limited." [](https://expedia.ca/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information) ![Inn @ Clemson](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d_y.jpg) ### Inn @ Clemson 10/10 Excellent "Clean Easy access Friendly staff helpful Been here before will use again " [](https://expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "The staff especially stood out. The online check in and the front desk was an absolute breeze! I am pleased as all heck. The room was clean and is well laid out for me to work. I greatly appreciate it." [](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Tru by Hilton Seneca Clemson](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/10f1fcf8_y.jpg) ### Tru by Hilton Seneca Clemson 10/10 Excellent "Perfect stay for a weekend. Lots of shopping and restaurants nearby. Clean safe area annd the staff was wonderful!" [](https://expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Hilton Garden Inn Anderson](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/78e2a715_y.jpg) ### Hilton Garden Inn Anderson 10/10 Excellent "Clean room. Indoor pool. Great place to stay" [](https://expedia.ca/Anderson-Hotels-Hilton-Garden-Inn-Anderson.h1340606.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Best Western Hotels in Aiken ](https://www.expedia.ca/Aiken-Hotels-Best-Western.0-0-d6058112--bBestWestern.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Beech Island ](https://www.expedia.ca/Beech-Island-Hotels-Hilton-Hotels.0-0-d3000353088--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Brookhaven ](https://www.expedia.ca/Brookhaven-Hotels-Motel-6.0-0-d553248635975852330--bMotel6.Travel-Guide-Filter-Hotels) - [Aparthotels in Central ](https://www.expedia.ca/Central-Apart-Hotels.d10503-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Central ](https://www.expedia.ca/Central-Bed-And-Breakfast.d10503-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Boutique Hotels in Central ](https://www.expedia.ca/Central-Hotels-Boutique-Hotel.0-0-d10503-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - 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