Title: Hotels by America's Best Inns in Clemson | Expedia.ca [Clemson Travel Guide](https://expedia.ca/Clemson.dx6594)[Hotels in Clemson](https://expedia.ca/Clemson-Hotels.d6594.Travel-Guide-Hotels)[Vacation Rentals in Clemson](https://expedia.ca/Clemson-Vacation-Rentals.d6594.Travel-Guide-VacationRentals)[Flights to Clemson](https://expedia.ca/Cheap-Flights-To-Clemson.d6594.Travel-Guide-Flights)[Clemson Car Rentals](https://expedia.ca/Car-Rentals-In-Clemson.d6594.Car-Rental-Guide)[Clemson Vacation Packages](https://expedia.ca/Clemson.d6594.Destination-Travel-Guides) ![Sunset on the Docks in Clemson, South Carolina; Shutterstock ID 1068665087; purchase_order: SP-1269 HA 2018 Batch 1; Order: ; client: ; other:](https://images.trvl-media.com/place/6594/3559af33-8fc4-4b07-8fe6-f8db466d3d41.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6594/3559af33-8fc4-4b07-8fe6-f8db466d3d41.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 2 - Mar 3](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2026-03-02&endDate=2026-03-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 3 - Mar 4](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2026-03-03&endDate=2026-03-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FClemson-Hotels-Americas-Best-Inns.0-0-d6594--bAmericasBestInns.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FClemson-Hotels-Americas-Best-Inns.0-0-d6594--bAmericasBestInns.Travel-Guide-Filter-Hotels) ## Top Clemson Hotel Reviews ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "N/a" [](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Hampton Inn & Suites Seneca-Clemson Area](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9_y.jpg) ### Hampton Inn & Suites Seneca-Clemson Area 10/10 Excellent "Great having a washer and dry available and the breakfast staff was amazing and very nice." [](https://expedia.ca/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) ![Days Inn by Wyndham Anderson](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24_y.jpg) ### Days Inn by Wyndham Anderson 10/10 Excellent "Great place to stay. Very quiet and well kept. Employees are super nice!" [](https://expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Lakeside Lodge Clemson](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/db449d90_y.jpg) ### Lakeside Lodge Clemson 10/10 Excellent "Clean room, great service!" [](https://expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "All was excellent" [](https://expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Inn @ Clemson](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d_y.jpg) ### Inn @ Clemson 10/10 Excellent "great place to stay very clean looks just like the pictures they displayed " [](https://expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Clemson University's James F. Martin Inn](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/ad943919_y.jpg) ### Clemson University's James F. Martin Inn 10/10 Excellent "Great!" [](https://expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ![Quality Inn Seneca Clemson Area US-123](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2_y.jpg) ### Quality Inn Seneca Clemson Area US-123 10/10 Excellent "All great" [](https://expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![The Inn at Patrick Square](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/4d00561c_y.jpg) ### The Inn at Patrick Square 10/10 Excellent "Always classy" [](https://expedia.ca/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Best Western Hotels in Aiken ](https://www.expedia.ca/Aiken-Hotels-Best-Western.0-0-d6058112--bBestWestern.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Beech Island ](https://www.expedia.ca/Beech-Island-Hotels-Hilton-Hotels.0-0-d3000353088--bHiltonHotels.Travel-Guide-Filter-Hotels) - 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