Title: Book the Best Clarksville SPA Resorts from CA $122 - Spa Hotels in Clarksville, IN | Expedia.ca [Hotels in Clarksville](https://expedia.ca/Clarksville-Hotels.d9727.Travel-Guide-Hotels)[Vacation Rentals in Clarksville](https://expedia.ca/Clarksville-Vacation-Rentals.d9727.Travel-Guide-VacationRentals)[Flights to Clarksville](https://expedia.ca/Cheap-Flights-To-Clarksville.d9727.Travel-Guide-Flights)[Clarksville Car Rentals](https://expedia.ca/Car-Rentals-In-Clarksville.d9727.Car-Rental-Guide)[Clarksville Vacation Packages](https://expedia.ca/Clarksville.d9727.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/0c863246a008e16466acfd80fe55a9ec.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Clarksville, IN from CA $122 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Clarksville Spa Hotels Tonight [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=9727&startDate=2025-10-24&endDate=2025-10-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=9727&startDate=2025-10-25&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=9727&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=9727&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Clarksville Spa Hotels ![Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/90ea7f39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/00e4c915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/eb0ea4ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/2ec829de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Reserve on Main Downtown Louisville [](https://www.expedia.ca/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information) ![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/ab0af7cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9c82234b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/594caae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Galt House Hotel Trademark Collection by Wyndham Downtown Louisville 9.0/10 Wonderful (3696) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tia CA $182 CA $215 total includes taxes & fees Nov 22 - Nov 23 [](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/80fbdedc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/2339d325.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/54f0e03a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/bea44cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Caesars Southern Indiana - A Caesars Rewards Destination Elizabeth 8.2/10 Very good (1020) "Easy parking, Very friendly/helpful staff, easy check in/out, Nice casino, Good food options" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie CA $85 CA $122 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information) ![Sauna, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/e108d0ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/w5757h3840x3y0-b0a2f211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/9798709f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Louisville Hotel Downtown Louisville 9.2/10 Wonderful (1646) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Abby CA $279 CA $328 total includes taxes & fees Nov 15 - Nov 16 [](https://www.expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/cef338e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Louisville Downtown Louisville 9.2/10 Wonderful (1001) "Great stay overall. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeannette CA $225 CA $272 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-07&endDate=2025-11-08®ionId=9727&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Clarksville Hotel Reviews ![Courtyard by Marriott Louisville Airport](//images.trvl-media.com/lodging/1000000/880000/874400/874388/9148c40a_y.jpg) ### Courtyard by Marriott Louisville Airport 10/10 Excellent "Great" [](https://expedia.ca/Louisville-Hotels-Courtyard-By-Marriott-Louisville-Airport.h874388.Hotel-Information) ![Galt House Hotel Trademark Collection by Wyndham](//images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg) ### Galt House Hotel Trademark Collection by Wyndham 10/10 Excellent "Amazing hotel " [](https://expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Clarksville? > Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the gourmet restaurants in Clarksville. Enjoy the shopping and waterfalls during your vacation. Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your vacation. ### What's there to see and do in Clarksville? > When you're in Clarksville, enjoy exploring the sights and attractions here including Ohio River Valley, Derby Dinner Playhouse, and Falls of the Ohio State Park. If you have a little extra time during your trip, you might want to check out Atlantis Waterpark and Silver Lakes. ### What is a Clarksville spa hotel? > Spa hotels in Clarksville provide lodging and have a full on-site spa which offers services such as couples massages as well as body treatments. Some also offer in-room treatments. 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