Book the Best Clarksville SPA Resorts from CA $122 - Spa Hotels in Clarksville, IN

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Our top choices for Clarksville hotels with a spa

4 restaurants; breakfast, lunch, and dinner served

In-room safe, desk, laptop workspace, iron/ironing board

1. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville

Riverside sanctuary offers rejuvenating spa treatments, panoramic fitness views, and river-facing balconies for a relaxing urban retreat.

CA $227

CA $267 total

includes taxes & fees

Oct 4 - Oct 5

2. 21c Museum Hotel Louisville

Downtown Louisville

Experience a rejuvenating spa escape at this luxury boutique hotel with massage rooms and 24-hour fitness centre in downtown Louisville.

CA $272

CA $327 total

includes taxes & fees

Oct 11 - Oct 12

3 bars/lounges, cocktail bar, lobby lounge

Outdoor pool, open 6:00 AM to 10:00 PM, cabanas (surcharge)

3. Omni Louisville Hotel

Downtown Louisville

Immerse in spa bliss at this Louisville hotel where Mokara Spa offers therapeutic treatments and rooftop relaxation awaits.

CA $391

CA $460 total

includes taxes & fees

Sep 30 - Oct 1

3 restaurants; breakfast, lunch, and dinner served

4. Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination

Elizabeth

Refresh your spirit at this riverfront hotel with daily spa treatments and couples rooms, where aromatherapy and Ayurvedic therapies await.

CA $85

CA $122 total

includes taxes & fees

Oct 18 - Oct 19

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Choose what matters most at spa hotels in Clarksville

Pool

Hot tub

Breakfast included

4 stars

5 stars

Top Clarksville Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Clarksville?

Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the gourmet restaurants in Clarksville. Enjoy the shopping and waterfalls during your vacation. Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your vacation.

What's there to see and do in Clarksville?

When you're in Clarksville, enjoy exploring the sights and attractions here including Derby Dinner Playhouse, Falls of the Ohio State Park, and Ohio River Valley. If you have a little extra time during your trip, you might want to check out Atlantis Waterpark and Old Clarksville Site.

What is a Clarksville spa hotel?

Spa hotels in Clarksville provide lodging and have a full on-site spa which offers services such as couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.