Title: Central Guest Houses from CA $93 | Expedia.ca [Hotels in Central](https://expedia.ca/Central-Hotels.d10503.Travel-Guide-Hotels)[Vacation Rentals in Central](https://expedia.ca/Central-Vacation-Rentals.d10503.Travel-Guide-VacationRentals)[Central Car Rentals](https://expedia.ca/Car-Rentals-In-Central.d10503.Car-Rental-Guide)[Central Vacation Packages](https://expedia.ca/Central.d10503.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/bf6bd00b15bd0fdc085d2f42cfcfc08c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Watts # Search Guest Houses in Central from CA $93 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=10503&startDate=2025-10-24&endDate=2025-10-26&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=10503&startDate=2025-10-31&endDate=2025-11-02&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=10503&startDate=2025-11-14&endDate=2025-11-16&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=10503&startDate=2025-12-12&endDate=2025-12-14&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Central Guest Houses We don't have any properties that match your exact search [See all properties in Central](https://expedia.ca/Hotel-Search?startDate=2025-11-02&endDate=2025-11-03®ionId=10503&adults=2) ## Recommended hotels in Central ![Private kitchen](https://images.trvl-media.com/lodging/90000000/89680000/89679000/89678964/3d15c989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/90000000/89680000/89679000/89678964/ba4722d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/90000000/89680000/89679000/89678964/f0cde57a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/90000000/89680000/89679000/89678964/4e5e97d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TigerTown Retreat - Comfort Minutes from Campus Central 10/10 Exceptional (10) "Property was as described and having an awesome Mexican Restaurant right next door was a definite plus! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet S. CA $191 CA $414 total includes taxes & fees Oct 22 - Oct 23 [](https://www.expedia.ca/Central-Hotels-3br-APT-Perfect-Location-Clemson-Games-Visits.h89678964.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/121000000/120090000/120081400/120081318/df9a5d9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/121000000/120090000/120081400/120081318/d8f20be3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120090000/120081400/120081318/b1b2282f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, toilet paper](https://images.trvl-media.com/lodging/121000000/120090000/120081400/120081318/20e4b7b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3BR Basement Apartment Close to CU Central CA $126 CA $336 total includes taxes & fees Oct 22 - Oct 23 [](https://www.expedia.ca/Central-Hotels-3BR-Basement-Apartment-Close-To-CU.h120081318.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/120000000/119930000/119922300/119922213/87b36a36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119930000/119922300/119922213/a87451e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119930000/119922300/119922213/d8cb60e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119930000/119922300/119922213/2d35a2f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Upscale Lodge Sleeps 9 Dog Friendly Near CU Central CA $259 CA $518 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Central-Hotels-Upscale-Lodge-Sleeps-9-Dog-Friendly-Near-CU.h119922213.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/114000000/113560000/113551300/113551290/1e700c27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/114000000/113560000/113551300/113551290/a2c4fa76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/114000000/113560000/113551300/113551290/204cfbcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed](https://images.trvl-media.com/lodging/114000000/113560000/113551300/113551290/5a26fb29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield By Marriott Inn & Suites Piedmont Greenville Piedmont CA $195 CA $216 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Piedmont-Hotels-Fairfield-By-Marriott-Inn-Suites-Piedmont-Greenville.h113551290.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/7cb8ae6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/7bc9a82a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/f49d90aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Anderson Anderson 7.6/10 Good (1032) "Rooms were clean, the property was well kept, complimentary breakfast and location is close to everything. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kayla CA $83 CA $93 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/f93d0c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/94f8bd4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/706f626f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/14e3230b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Anderson/Clemson Anderson 8.2/10 Very good (1002) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) lee CA $104 CA $115 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Resort Studio with Kitchen and Two Queen | Private kitchen](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/70e13494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/d191b963.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/01158bad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson Seneca 9.0/10 Wonderful (1023) "Very beautiful place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven CA $153 CA $190 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Two queen beds nonsmoking](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/65554714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/f21c3602.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/c7944b9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/c13da5b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Easley Easley 9.4/10 Exceptional (659) "Great room and friendly staff 🤘" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Benjamin CA $178 CA $197 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Easley-Hotels-Hampton-Inn-Easley.h1453465.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/282fab11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2557x3y4-050d425f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Clemson Hotel & Conference Center Clemson 8.2/10 Very good (1016) "Great value and great hotel. We would stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew CA $118 CA $131 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/eab53b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/347fe1fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/3c50d204.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Seneca Clemson Area US-123 Downtown 8.0/10 Very good (648) "Friendly check in, clean room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) connie CA $112 CA $132 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/f18cfd05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/acae25f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 1 Single Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/4ce574a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/2d87513f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Easley/Greenville Easley 7.4/10 Good (714) "It was ok" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arthur CA $95 CA $105 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Easley-Hotels-Baymont-By-Wyndham-EasleyGreenville.h569381.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/e51fff20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/76bc86a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/ca80b104.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/f179f4b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Clemson - University Area Clemson 8.2/10 Very good (1009) "I loved the quietness and the staff was great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chantel CA $131 CA $146 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/d223eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/65f927f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Microwave (with Sofabed)](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/188dc421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/83901eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Seneca-Clemson Seneca 8.4/10 Very good (622) "Convenient for Clemson visits." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathleen CA $119 CA $131 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/9fe06894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/cc35e730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/e45ab30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/a9307e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Seneca Clemson Univ Area Seneca 9.4/10 Exceptional (199) "Nice hotel by the lake" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $181 CA $199 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/8c11b789.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge, stovetop, cookware/dishes/utensils, paper towels](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/18a62d98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/f29b16c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/f5941a87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy Seneca 9.8/10 Exceptional (42) "The place was absolutely magnificent." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $181 CA $261 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/5000000/4590000/4584800/4584724/620a9c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4590000/4584800/4584724/aacced25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4590000/4584800/4584724/ebee5c42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4590000/4584800/4584724/87ef0209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn Anderson 7.8/10 Good (303) "Good size room and convenient " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rick CA $84 CA $93 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Anderson-Hotels-Rodeway-Inn.h4584724.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/78e2a715.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/dfa7a980.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/7711c34b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/d53ff29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Anderson Anderson 9.0/10 Wonderful (655) "Ez check in" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samuel CA $154 CA $171 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Anderson-Hotels-Hilton-Garden-Inn-Anderson.h1340606.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/60389240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/e417f297.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/70604dbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/a3e9e5b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Anderson/ Alliance Business Park Anderson 9.2/10 Wonderful (786) "Everything was awesome the Lady at the front desk super nice friendly with the kids when we did the Check in, clean room, smells nice and clean, comfortable beds, and good breakfasts." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yazareth CA $154 CA $171 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Anderson-North.h3629858.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2860000/2853900/2853804/a2907878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2860000/2853900/2853804/09f18b06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2860000/2853900/2853804/ff24e798.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2860000/2853900/2853804/4c22534f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Greenville South Piedmont 8.2/10 Very good (657) "We have stayed here a few times and always are pleased with everything." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cheryl CA $141 CA $156 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Piedmont-Hotels-Best-Western-Plus-Greenville-South.h2853804.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269961/3ff1bced.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269961/520ba6f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269961/8ecfecae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269961/beafdd29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Greenville South Piedmont 8.8/10 Excellent (907) "Staff was very friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jackie CA $143 CA $159 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Piedmont-Hotels-Comfort-Suites-Greenville-South.h17269961.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-02&endDate=2025-11-03®ionId=10503&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCentral-Guest-Houses.d10503-aaGuestHouses.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCentral-Guest-Houses.d10503-aaGuestHouses.Travel-Guide-Accommodation) ## Top Central Hotel Reviews ![The Shepherd Hotel Downtown Clemson](//images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "Wonderful. Beautifully decorated and very personable and professional staff. " [](https://expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Days Inn by Wyndham Anderson](//images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24_y.jpg) ### Days Inn by Wyndham Anderson 10/10 Excellent "All good." [](https://expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Comfort Inn & Suites Clemson - University Area](//images.trvl-media.com/lodging/1000000/20000/19100/19019/e51fff20_y.jpg) ### Comfort Inn & Suites Clemson - University Area 10/10 Excellent "I loved the quietness and the staff was great. " [](https://expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Hilton Garden Inn Anderson](//images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/78e2a715_y.jpg) ### Hilton Garden Inn Anderson 10/10 Excellent "The room was very clean & spacious. Our dinner was very good. The breakfasr was exceptional. We were extra time to keep our room as our vehicle was in the shop unexpectedly. We were not charged for the extra time. The only negative was the tub was incredibly slippery." [](https://expedia.ca/Anderson-Hotels-Hilton-Garden-Inn-Anderson.h1340606.Hotel-Information) ![Lakeside Lodge Clemson](//images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff_y.jpg) ### Lakeside Lodge Clemson 10/10 Excellent "did not use it but looked good." [](https://expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Hampton Inn & Suites Seneca-Clemson Area](//images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9_y.jpg) ### Hampton Inn & Suites Seneca-Clemson Area 10/10 Excellent "All good. " [](https://expedia.ca/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) ![Baymont by Wyndham Easley/Greenville](//images.trvl-media.com/lodging/1000000/570000/569400/569381/f18cfd05_y.jpg) ### Baymont by Wyndham Easley/Greenville 10/10 Excellent "Loved everything. " [](https://expedia.ca/Easley-Hotels-Baymont-By-Wyndham-EasleyGreenville.h569381.Hotel-Information) ![Clemson University's James F. Martin Inn](//images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/49a2146a_y.jpg) ### Clemson University's James F. Martin Inn 10/10 Excellent "This is a beautiful inn on the outskirts of Clemson's campus. The room is spacious, has good lighting and the beds are comfortable!! They seem a little short on outlets/charging stations, but we would definitely stay here again and recommend this location!!!!" [](https://expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ![Comfort Suites Greenville South](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269961/3ff1bced_y.jpg) ### Comfort Suites Greenville South 10/10 Excellent "Clean" [](https://expedia.ca/Piedmont-Hotels-Comfort-Suites-Greenville-South.h17269961.Hotel-Information) ## Find out more about Central ## Central Guest Houses information | Number of reviews | 11,268 | | --- | --- | | Accommodation | 2 Guest Houses | | Lowest Price | CA $93 | | Highest Price | CA $518 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Aparthotels in Clemson](https://www.expedia.ca/Clemson-Apart-Hotels.d6594-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Clemson](https://www.expedia.ca/Clemson-Bed-And-Breakfast.d6594-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Clemson](https://www.expedia.ca/Clemson-Hotels-Cheap-Hotels.0-0-d6594-tCheapHotels.Travel-Guide-Filter-Hotels) - 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