Title: Book the Best Applegate LUXURY Hotels - Upscale Hotels in Applegate, OR | Expedia.ca [Hotels in Applegate](https://expedia.ca/Applegate-Hotels.d3000422437.Travel-Guide-Hotels)[Vacation Rentals in Applegate](https://expedia.ca/Applegate-Vacation-Rentals.d3000422437.Travel-Guide-VacationRentals)[Applegate Car Rentals](https://expedia.ca/Car-Rentals-In-Applegate.d3000422437.Car-Rental-Guide)[Applegate Vacation Packages](https://expedia.ca/Applegate.d3000422437.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/luxury.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Applegate Luxury Hotels Tonight [Feb 9 - Feb 10](https://www.expedia.ca/Hotel-Search?regionId=3000422437&startDate=2026-02-09&endDate=2026-02-10&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Feb 10 - Feb 11](https://www.expedia.ca/Hotel-Search?regionId=3000422437&startDate=2026-02-10&endDate=2026-02-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=3000422437&startDate=2026-02-13&endDate=2026-02-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=3000422437&startDate=2026-02-20&endDate=2026-02-22&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Applegate Hotel Reviews ![La Quinta Inn & Suites by Wyndham Grants Pass](https://images.trvl-media.com/lodging/1000000/210000/201100/201014/abb300e9_y.jpg) ### La Quinta Inn & Suites by Wyndham Grants Pass 10/10 Excellent "Great" [](https://expedia.ca/Medford-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Grants-Pass.h201014.Hotel-Information) ![Red Lion Inn & Suites Grants Pass](https://images.trvl-media.com/lodging/1000000/10000/3700/3635/3028b226_y.jpg) ### Red Lion Inn & Suites Grants Pass 10/10 Excellent "The room was very clean. Staff sitter friendly and great location." [](https://expedia.ca/Medford-Hotels-Red-Lion-Inn-Suites-Grants-Pass.h3635.Hotel-Information) ![Rogue Regency Inn and Suites](https://images.trvl-media.com/lodging/1000000/20000/19800/19703/8b20e842_y.jpg) ### Rogue Regency Inn and Suites 10/10 Excellent "Love it " [](https://expedia.ca/Medford-Hotels-Rogue-Regency-Inn-And-Suites.h19703.Hotel-Information) ![Riverside Inn](https://images.trvl-media.com/lodging/1000000/20000/13700/13698/927c75f6_y.jpg) ### Riverside Inn 10/10 Excellent "Beautiful views" [](https://expedia.ca/Medford-Hotels-Riverside-Inn.h13698.Hotel-Information) ![Hilton Garden Inn Medford, OR ](https://images.trvl-media.com/lodging/17000000/16080000/16070600/16070531/ca82bf1b_y.jpg) ### Hilton Garden Inn Medford, OR 10/10 Excellent "Friendly staff, clean room, comfortable bed and good pillows. It is nice that they included breakfast in the morning for a good price as well. What more can you ask for?" [](https://expedia.ca/Medford-Hotels-Hilton-Garden-Inn-Medford.h16070531.Hotel-Information) ![Best Western Inn At The Rogue](https://images.trvl-media.com/lodging/1000000/10000/3500/3483/285d1561_y.jpg) ### Best Western Inn At The Rogue 10/10 Excellent "Room was clean. Biscuits and gravy for breakfast!!" [](https://expedia.ca/Medford-Hotels-Best-Western-Inn-At-The-Rogue.h3483.Hotel-Information) ![Motel 6 Medford, OR](https://images.trvl-media.com/lodging/1000000/1000000/996200/996127/7ef01fa3_y.jpg) ### Motel 6 Medford, OR 10/10 Excellent "Yes" [](https://expedia.ca/Medford-Hotels-Motel-6-Medford.h996127.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Central Point - Medford](https://images.trvl-media.com/lodging/1000000/800000/797000/796949/1682e38d_y.jpg) ### La Quinta Inn & Suites by Wyndham Central Point - Medford 10/10 Excellent "Thank you " [](https://expedia.ca/Medford-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Central-Point-Medford.h796949.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury getaway to Applegate? ### When can I expect good weather in Applegate? ### What's there to see and do in Applegate? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [4 Star Hotels in Central Point ](https://www.expedia.ca/4Star-Central-Point-Hotels.s40-0-d602408.Travel-Guide-Filter-Hotels) - 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