Title: 5 Stars Hotels in São Tomé Island, São Tomé and Príncipe from CA $321 - Find Cheap São Tomé Island Hotels With 5 Stars | Expedia.ca

[São Tomé Island Travel Guide](https://expedia.ca/Sao-Tome-Island.dx3486)[Hotels in São Tomé Island](https://expedia.ca/Sao-Tome-Island-Hotels.d3486.Travel-Guide-Hotels)[Vacation Rentals in São Tomé Island](https://expedia.ca/Sao-Tome-Island-Vacation-Rentals.d3486.Travel-Guide-VacationRentals)[Flights to São Tomé Island](https://expedia.ca/Cheap-Flights-To-Sao-Tome-Island.d3486.Travel-Guide-Flights)[Things to do in São Tomé Island](https://expedia.ca/Things-To-Do-In-Sao-Tome-Island.d3486.Travel-Guide-Activities)[São Tomé Island Car Rentals](https://expedia.ca/Car-Rentals-In-Sao-Tome-Island.d3486.Car-Rental-Guide)[São Tomé Island Vacation Packages](https://expedia.ca/Sao-Tome-Island.d3486.Destination-Travel-Guides)

![A pretty sunset in São Tomé.](https://images.trvl-media.com/place/553248635976006815/07aca925-8318-4676-9191-b2ca4e7702d9.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Toshiaki Yoshitake

# 5 Stars Hotels in São Tomé Island, São Tomé and Príncipe from CA $321

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## Check availability on São Tomé Island 5 Star Hotels

Tonight

[Jan 7 - Jan 8](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2026-01-07&endDate=2026-01-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Jan 8 - Jan 9](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2026-01-08&endDate=2026-01-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2026-01-09&endDate=2026-01-11&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=3486&startDate=2026-01-16&endDate=2026-01-18&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for São Tomé Island 5-star hotels

![Pool](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/4b0f9c44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![On the beach, sun loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/bb670e49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool views, open daily](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/b432c63a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Minibar, in-room safe, free WiFi](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/bab15252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pestana São Tomé

[](https://www.expedia.ca/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information)

Vila Maria

8.0/10

Very good

(78)

"Wonderful stay, great staff, easy, relaxing delightful."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

alexander

CA $273

CA $321 total

includes taxes & fees

Jan 8 - Jan 9

[](https://www.expedia.ca/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information)

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in São Tomé Island.

![Omali São Tomé – Principe Collection](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d1688203_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Omali São Tomé – Principe Collection

Praia Lagarto São Tomé 

CA $280

CA $332 total

Jan 14 - Jan 15

includes taxes & fees

9.4/10 Exceptional! (62 reviews)

[](https://expedia.ca/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information)

Still don't see what you're looking for?

[See all properties in São Tomé Island.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F01%2F2026&endDate=09%2F01%2F2026&regionId=3486&star=50)

You can also use these popular filters to refine your search.

[Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F01%2F2026&endDate=09%2F01%2F2026&regionId=3486&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F01%2F2026&endDate=09%2F01%2F2026&regionId=3486&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F01%2F2026&endDate=09%2F01%2F2026&regionId=3486&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F01%2F2026&endDate=09%2F01%2F2026&regionId=3486&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=08%2F01%2F2026&endDate=09%2F01%2F2026&regionId=3486&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about São Tomé Island

Check out the local area in São Tomé Island—home to attractions like Pico São Tomé and Estadio Nacional 12 de Julho.

[See all hotels in São Tomé Island](https://www.expedia.ca/Hotel-Search?startDate=2026-01-21&endDate=2026-01-22&adults=2&regionId=3486)

![Nice place, good food... Quite difficult to reach, you need a good car...](https://images.trvl-media.com/place/553248621565299214/edf5448a-52b1-44ed-852d-bc5327dd1c36.jpg?impolicy=fcrop&w=225&h=400&p=1&q=high)

Photo by Fabrice Récalt

## Top São Tomé Island Hotel Reviews

![Pestana São Tomé](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/ea6ea619_y.jpg)

### Pestana São Tomé

10/10 Excellent

"Wonderful stay, great staff, easy, relaxing delightful."

[](https://expedia.ca/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information)

## Find out more about São Tomé Island

## Five Star Hotels in São Tomé Island

There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made São Tomé Island so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in São Tomé Island and get ready to be pampered like never before.

#### Get a Great Deal on 5-Star Hotels in São Tomé Island

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places. 

Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town.

#### Make Your Escape to São Tomé Island

The results are in, and São Tomé Island 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in São Tomé Island! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in São Tomé Island today and settle down in the lap of luxury tomorrow.

## Frequently asked questions

### How much does it cost to stay in a 5-star hotel in São Tomé Island?

> - Search for the lowest price per night from CA $332

### What makes a hotel 5 stars in São Tomé Island?

### Are there any 5-star all-inclusive resorts in São Tomé Island?

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