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5 Stars Hotels in Santa Ana, California from CA $195

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Check availability on Santa Ana 5 Star Hotels

Tonight
Oct 9 - Oct 10
Tomorrow
Oct 10 - Oct 11
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Santa Ana 5-star hotels

A stone fire pit surrounded by palm trees and chairs in an outdoor seating area.
A modern hotel room with a sofa, armchair, ottoman, kitchenette, and a television.
A panoramic view of a hotel room with a living area, bedroom, and kitchenette.
A gift shop with a Pepsi refrigerator, shelves with various items, and a glass display case with knick-knacks.

1. MainStay Suites John Wayne Airport by Choice Hotels

MainStay Suites John Wayne Airport by Choice Hotels
Santa Ana
United States
Yvonne
CA $132
CA $149 total
includes taxes & fees
Nov 1 - Nov 2
MainStay Suites John Wayne Airport by Choice Hotels
A multi-level hotel atrium with a central courtyard, multiple balconies, and indoor seating areas.
A spacious lobby with a grey sectional sofa set, two round coffee tables, and a patterned carpet.
A modern office space with two desks, each with a computer and keyboard, and a large decorative vase.
A multi-level hotel lobby with a central water feature, seating areas, and balconies.

2. Embassy Suites by Hilton Santa Ana Orange County Airport

Embassy Suites by Hilton Santa Ana Orange County Airport
Santa Ana
United States
Nariman
CA $168
CA $190 total
includes taxes & fees
Oct 25 - Oct 26
Embassy Suites by Hilton Santa Ana Orange County Airport
A modern bar area with a wooden counter, orange bar stools, and a flat-screen TV mounted on the wall.
A spacious lobby with a reception desk, seating area, and a staircase leading to upper floors.
A hotel entrance with a prominent sign, palm trees, and a parking lot.
A modern lounge area with a flat-screen TV, a fireplace, and comfortable seating.

3. La Quinta Inn & Suites by Wyndham Orange County Airport

La Quinta Inn & Suites by Wyndham Orange County Airport
Santa Ana
United States
Chanho
CA $128
CA $144 total
includes taxes & fees
Oct 25 - Oct 26
La Quinta Inn & Suites by Wyndham Orange County Airport
A hotel lobby with seating areas, a reception desk, and a large window offering a view of the outside.
A pool area with a hot tub, lounge chairs, and a covered grill.
An outdoor patio with tables and chairs, shaded by large umbrellas, and surrounded by palm trees and a hedge.
A modern lobby with a stone wall, a flat-screen TV, and comfortable seating.

4. Best Western Plus Orange County Airport North

Best Western Plus Orange County Airport North
Santa Ana
United States
Sheri
CA $155
CA $175 total
includes taxes & fees
Nov 1 - Nov 2
Best Western Plus Orange County Airport North
A hotel room with a bed, a desk, a chair, a lamp, a TV, and a window with a view of trees.
A conference room with rows of chairs, a patterned carpet, and a large chandelier.
A gym with treadmills, stationary bikes, and exercise equipment.
A pier with a red-roofed building, extending into the ocean with waves crashing against it.

5. Holiday Inn Santa Ana-Orange Co. Arpt by IHG

Holiday Inn Santa Ana-Orange Co. Arpt by IHG
Santa Ana
United States
Camilla
CA $174
CA $196 total
includes taxes & fees
Oct 22 - Oct 23
Holiday Inn Santa Ana-Orange Co. Arpt by IHG
An outdoor seating area with wicker furniture, a central fire pit, and a pool in the background.
A hotel room with a bed, a desk with a chair, a television, a sofa, and a mirror.
A rooftop pool area with lounge chairs and a fire pit, surrounded by a fence and overlooking a multi-story building.
A Comfort Inn & Suites with a stone facade, large windows, and a covered entrance area.

6. Comfort Inn & Suites Orange County John Wayne Airport

Comfort Inn & Suites Orange County John Wayne Airport
Santa Ana
United States
Kandise
CA $133
CA $151 total
includes taxes & fees
Oct 25 - Oct 26
Comfort Inn & Suites Orange County John Wayne Airport
A modern hotel with a pool, palm trees, and a parking area.
A modern bar area with a curved counter, multiple seating options, and a variety of liquor bottles and glasses.
A cozy outdoor seating area with wicker furniture and a central fire feature.
A television displaying a Courtyard by Marriott hotel with a view of the building's exterior.

7. Courtyard by Marriott Santa Ana Orange County

Courtyard by Marriott Santa Ana Orange County
Santa Ana
United States
Brittany
CA $172
CA $194 total
includes taxes & fees
Oct 11 - Oct 12
Courtyard by Marriott Santa Ana Orange County
An outdoor patio area with tables and chairs, umbrellas, and a view of a water body and buildings.
A modern hotel room with a dining area, seating, and large windows offering a city view.
A modern hotel room with a sofa set, a dining table, and a kitchen area.
A hotel room with a large bed, a view of high-rise buildings, and a window with curtains.

8. voco Orange County - Airport by IHG

voco Orange County - Airport by IHG
Santa Ana
United States
Gabriela
CA $162
CA $184 total
includes taxes & fees
Nov 9 - Nov 10
voco Orange County - Airport by IHG
Coffee shop
Room
Fitness facility
Lobby

9. Hotel Zessa Orange County Airport, a DoubleTree by Hilton

Hotel Zessa Orange County Airport, a DoubleTree by Hilton
Santa Ana
United States
Alexis
CA $192
CA $217 total
includes taxes & fees
Oct 30 - Oct 31
Hotel Zessa Orange County Airport, a DoubleTree by Hilton
An outdoor seating area with a circular fire pit surrounded by wicker furniture and a stone fire table.
A modern hotel lobby with a sofa, armchairs, a coffee table, and a fireplace.
A refrigerated display case with various beverages and snacks, a sign reading "the market", and a wooden wall with the word "market" in illuminated letters.
A modern bar area with high stools, a counter, and a wine display.

10. Courtyard by Marriott Costa Mesa South Coast Metro

Courtyard by Marriott Costa Mesa South Coast Metro
Santa Ana
Canada
Cheryl
CA $201
CA $229 total
includes taxes & fees
Oct 18 - Oct 19
Courtyard by Marriott Costa Mesa South Coast Metro
A modern living area with a sectional sofa, two armchairs, a coffee table, and a kitchen area with a refrigerator and shelves.
A hotel room with two beds, a TV, a wardrobe, and a large window with a view of buildings.
A modern gym with various exercise equipment, large windows, and a flat-screen TV.
A modern living room with a sectional sofa, a coffee table, and a TV. There are large windows with curtains, a plant, and a desk with a chair.

11. City Express by Marriott Santa Ana/Orange County Airport

City Express by Marriott Santa Ana/Orange County Airport
Santa Ana
United States
sergio
CA $156
CA $177 total
includes taxes & fees
Oct 15 - Oct 16
City Express by Marriott Santa Ana/Orange County Airport
A kitchenette with a microwave, hot water bottles, and a coffee machine.
A pool area with a fenced deck, surrounded by a white fence, and a building with a red roof in the background.
A spacious lobby with a reception desk, a staircase to an upper level, and a sign welcoming smart travelers.
A well-maintained courtyard with a central pathway, surrounded by neatly trimmed hedges and trees.

12. Motel 6 Irvine - Orange County Airport

Motel 6 Irvine - Orange County Airport
Santa Ana
United States
Edwardo
CA $102
CA $116 total
includes taxes & fees
Oct 19 - Oct 20
Motel 6 Irvine - Orange County Airport
A hotel room with a large bed, a desk, a chair, a TV, and a balcony with curtains.
A Holiday Inn Express hotel with a parking lot and palm trees.
A breakfast bar with labeled sections for cereal, fruit, and yogurt.
A coffee station with two espresso machines, a coffee grinder, and various coffee-related items.

13. Holiday Inn Express & Suites Santa Ana - Orange County by IHG

Holiday Inn Express & Suites Santa Ana - Orange County by IHG
Lyon Street
United States
Lane
CA $162
CA $184 total
includes taxes & fees
Nov 8 - Nov 9
Holiday Inn Express & Suites Santa Ana - Orange County by IHG
A compact kitchen with a dining table, a microwave, a coffee maker, and a refrigerator.
A hotel room with a large bed, a desk with a chair, a kitchenette, and a TV.
A hotel with a modern design, featuring a prominent entrance with a sign, surrounded by palm trees and a clear blue sky.
A kitchen cabinet with multiple shelves containing kitchen appliances and storage containers.

14. Sonesta Simply Suites Orange County Airport

Sonesta Simply Suites Orange County Airport
Santa Ana
United States
Robert
CA $148
CA $167 total
includes taxes & fees
Nov 1 - Nov 2
Sonesta Simply Suites Orange County Airport
A coastal sunset view with palm trees and a pathway leading to a building.
A modern hotel with a large water fountain in the courtyard, surrounded by palm trees and a reflective pond.
A gym with weightlifting equipment, treadmills, and a mirrored wall.
An outdoor patio area with wicker chairs and tables, large umbrellas, and a view of a building and a body of water in the background.

15. Near South Coast Plaza | Pool, Dining + Spa

Near South Coast Plaza | Pool, Dining + Spa
Santa Ana
United States
Lynnelle
CA $146
CA $194 total
includes taxes & fees
Nov 9 - Nov 10
Near South Coast Plaza | Pool, Dining + Spa
A hotel room with two beds, a desk, and a chair.
A pet waste station with a sign, a trash bin, and a fence.
A hotel entrance with a 'Welcome' sign, a covered outdoor area, and a parking lot.
A hotel room with a blue sofa, a white bed, a small table, and a wall-mounted light.

16. Motel 6 Santa Ana, CA

Motel 6 Santa Ana, CA
Santa Ana
United States
Melisa
CA $114
CA $133 total
includes taxes & fees
Oct 12 - Oct 13
Motel 6 Santa Ana, CA
A hotel room with two beds, a TV, a desk with a lamp, a chair, and a bathroom visible in the background.
A building with a covered parking area, a brick wall, and a small window.
A bathroom with a sink, toilet, and shower.
A reception area with a glass partition, a clock, a sign indicating service availability, a flower vase, and a QR code on a counter.

17. Studio 6 Suites Santa Ana, Ca

Studio 6 Suites Santa Ana, Ca
Santa Ana
United States
Elizabeth
CA $149
CA $166 total
includes taxes & fees
Oct 11 - Oct 12
Studio 6 Suites Santa Ana, Ca
A hotel room with two beds, each with white bedding and a patterned runner. There are wall-mounted lights above each bed, and a framed picture on the wall.
A hotel lobby with a seating area, a reception desk, and a view of the street outside.
A Red Roof Inn with a large red sign, a parking lot, and a building with a red roof.
A laundry room with stacked washers and dryers, a notice sign, and a service sign.

18. Red Roof Inn Santa Ana

Red Roof Inn Santa Ana
Santa Ana
United States
Jay
CA $142
CA $161 total
includes taxes & fees
Oct 11 - Oct 12
Red Roof Inn Santa Ana
A hotel room with a bed, a desk with a chair, a TV, a large window with curtains, a bathroom with a bathtub, and a tiled floor.
A hotel lobby with a large window, a wooden reception desk, and a wall-mounted display of brochures.
A room with a large window, a sofa, a chair, a small table, and a plant.
A kitchen with a coffee machine, a window with curtains, and a mural on the wall.

19. Rodeway Inn Santa Ana - Garden Grove

Rodeway Inn Santa Ana - Garden Grove
Santa Ana
United States
Mary
CA $153
CA $175 total
includes taxes & fees
Nov 9 - Nov 10
Rodeway Inn Santa Ana - Garden Grove
A corridor with a red carpet, columns, and balconies with railings.
A two-story building with a red-tiled roof, balconies, and a parking lot with cars.
A motel with a sign advertising low rates.
A hotel room with a bed, a door, a mirror, and a coat rack.

20. Santa Ana Travel Inn

Santa Ana Travel Inn
Santa Ana
United States
Shukrullah
CA $73
CA $81 total
includes taxes & fees
Oct 29 - Oct 30
Santa Ana Travel Inn
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Ana.
Hilton Anaheim

Hilton Anaheim

777 W Convention Way Anaheim CA
CA $247
CA $292 total
Oct 18 - Oct 19
includes taxes & fees
Hilton Anaheim
Knott's Hotel

Knott's Hotel

7675 Crescent Ave Buena Park CA
CA $171
CA $195 total
Nov 8 - Nov 9
includes taxes & fees
Knott's Hotel
Hyatt Regency Orange County

Hyatt Regency Orange County

11999 Harbor Blvd Garden Grove CA
CA $183
CA $248 total
Oct 11 - Oct 12
includes taxes & fees
Hyatt Regency Orange County
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Ana

Historic downtown offers vibrant art walks and the best authentic tacos you'll find at 4th Street Market. Nearby, families love the interactive exhibits at Discovery Cube and the lush trails of Santiago Oaks Regional Park.

See all hotels in Santa Ana
A sandy path leading to a body of water, with a wooden fence and bench, under a colorful sunset sky.

Top Santa Ana Hotel Reviews

Find out more about Santa Ana

Five Star Hotels in Santa Ana

There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Santa Ana so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Santa Ana and get ready to be pampered like never before.

Get a Great Deal on 5-Star Hotels in Santa Ana

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places.

Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town.

Make Your Escape to Santa Ana

The results are in, and Santa Ana 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Santa Ana! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Santa Ana today and settle down in the lap of luxury tomorrow.

Frequently asked questions

What are the best 5-star hotels in Santa Ana?
If you're looking for a 5-star experience, Pendry Newport Beach offers one of the best of them based on reviews by our travellers. Choose this Santa Ana getaway and get ready for impeccable service, luxurious guest rooms and superior amenities.
How much does it cost to stay in a 5-star hotel in Santa Ana?
How much you pay for a 5-star hotel in Santa Ana can vary according to the time of year you travel and how long you plan to be away, among a range of factors. Use our price per night filter and other search tools to land the best rate on an indulgent stay.
  • Search for the lowest price per night from CA $195
What makes a hotel 5 stars in Santa Ana?
From gourmet restaurants and fitness centres to swimming pools and superior bedding, the 5-star experience in Santa Ana is all about luxury and comfort. But it takes more than just upscale amenities to receive a 5-star rating. Hotels also have to offer outstanding guest-centric services like in-room massage treatments, laundry and dry cleaning and 24-hour concierge services.

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