Title: 5 Stars Hotels in Adrian, Missouri - Find Cheap Adrian Hotels With 5 Stars | Expedia.ca [Adrian Travel Guide](https://expedia.ca/Adrian.dx3000421349)[Hotels in Adrian](https://expedia.ca/Adrian-Hotels.d3000421349.Travel-Guide-Hotels)[Vacation Rentals in Adrian](https://expedia.ca/Adrian-Vacation-Rentals.d3000421349.Travel-Guide-VacationRentals)[Flights to Adrian](https://expedia.ca/Cheap-Flights-To-Adrian.d3000421349.Travel-Guide-Flights)[Adrian Car Rentals](https://expedia.ca/Car-Rentals-In-Adrian.d3000421349.Car-Rental-Guide)[Adrian Vacation Packages](https://expedia.ca/Adrian.d3000421349.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Adrian, Missouri ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Adrian 5 Star Hotels Tonight [Sep 11 - Sep 12](https://www.expedia.ca/Hotel-Search?regionId=3000421349&startDate=2025-09-11&endDate=2025-09-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 12 - Sep 13](https://www.expedia.ca/Hotel-Search?regionId=3000421349&startDate=2025-09-12&endDate=2025-09-13&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 12 - Sep 14](https://www.expedia.ca/Hotel-Search?regionId=3000421349&startDate=2025-09-12&endDate=2025-09-14&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Sep 19 - Sep 21](https://www.expedia.ca/Hotel-Search?regionId=3000421349&startDate=2025-09-19&endDate=2025-09-21&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Adrian 5 Star Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Adrian-Hotels.s50-0-d3000421349.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Adrian-Hotels.s50-0-d3000421349.Travel-Guide-Filter-Hotels) ## Top Adrian Hotel Reviews ## Find out more about Adrian Luxury is the name of the game at the best 5 Stars hotels in Adrian. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Adrian 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them. Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Adrian hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Adrian without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Adrian. ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Adrian Hotels by Star Rating - [2 Star Hotels in Adrian](https://expedia.ca/2Star-Adrian-Hotels.s20-0-d3000421349.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Adrian](https://expedia.ca/3Star-Adrian-Hotels.s30-0-d3000421349.Travel-Guide-Filter-Hotels) ### Hotels near Popular Adrian Attractions - [Hotels near Truman Lake](https://expedia.ca/Truman-Lake-Hotels.0-l6129166-0.Travel-Guide-Filter-Hotels) - [Hotels near La Cygne Lake](https://expedia.ca/La-Cygne-Lake-Hotels.0-l553248621532648186-0.Travel-Guide-Filter-Hotels) - [Hotels near Louisburg Cider Mill](https://expedia.ca/Louisburg-Cider-Mill-Hotels.0-l553248635950847930-0.Travel-Guide-Filter-Hotels) - [Hotels near Marais des Cygnes National Wildlife Refuge](https://expedia.ca/Marais-Des-Cygnes-National-Wildlife-Refuge-Hotels.0-l553248635950848032-0.Travel-Guide-Filter-Hotels) - [Hotels near Isinglass Estate](https://expedia.ca/Isinglass-Estate-Hotels.0-l553248635950847996-0.Travel-Guide-Filter-Hotels) - [Hotels near Butler Recreational Lake](https://expedia.ca/Butler-Recreational-Lake-Hotels.0-l553248626388094094-0.Travel-Guide-Filter-Hotels) - [Hotels near Harrisonville City Park](https://expedia.ca/Harrisonville-City-Park-Hotels.0-l553248621571049646-0.Travel-Guide-Filter-Hotels) - [Hotels near Somerset Ridge Vineyard and Winery](https://expedia.ca/Somerset-Ridge-Vineyard-And-Winery-Hotels.0-l553248621532659005-0.Travel-Guide-Filter-Hotels) - [Hotels near Butler Country Club](https://expedia.ca/Butler-Country-Club-Hotels.0-l553248626388094087-0.Travel-Guide-Filter-Hotels) - [Hotels near Harrisonville Golf Club](https://expedia.ca/Harrisonville-Golf-Club-Hotels.0-l553248621571049648-0.Travel-Guide-Filter-Hotels) - [Hotels near Bates County Memorial Hospital](https://expedia.ca/Bates-County-Memorial-Hospital-Hotels.0-l553248626388094080-0.Travel-Guide-Filter-Hotels) - [Hotels near Cass Regional Medical Center](https://expedia.ca/Cass-Regional-Medical-Center-Hotels.0-l553248621571049650-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Adrian - [Vacation Homes in Adrian](https://expedia.ca/Adrian-Private-Vacation-Homes.d3000421349-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Cabin Rentals in Adrian](https://expedia.ca/Adrian-Cabins.d3000421349-aaCabins.Travel-Guide-Accommodation) - [Cottages in Adrian](https://expedia.ca/Adrian-Cottages.d3000421349-aaCottages.Travel-Guide-Accommodation) - [Motels in Adrian](https://expedia.ca/Adrian-Motels.d3000421349-aaMotels.Travel-Guide-Accommodation) - [Apartments in Adrian](https://expedia.ca/Adrian-Apartments.d3000421349-aaApartments.Travel-Guide-Accommodation) - [B&B in Adrian](https://expedia.ca/Adrian-Bed-And-Breakfast.d3000421349-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Lodges in Adrian](https://expedia.ca/Adrian-Lodges.d3000421349-aaLodges.Travel-Guide-Accommodation) ### Recommended Cities for You - 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[Inviting Lakefront A-Frame Cabin](https://expedia.ca/La-Cygne-Hotels-Cozy-3-Bedroom-A-Frame-Cabin-At-Tanglewood-Lakes-Near-LaCygne.h118253968.Hotel-Information) - [Bungaloft in charming Louisburg with AC, WiFi, Tv.](https://expedia.ca/Louisburg-Hotels-Cozy-Bungalow-In-Charming-Louisburg-With-AC.h108791275.Hotel-Information) - [A one-of-a-kind Log Lodge on over 200 acres of panoramic views & serene settings](https://expedia.ca/Drexel-Hotels-A-One-Of-A-Kind-Log-Lodge-On-Over-200-Acres-Of-Panoramic-Views-Serene-Settings.h77993894.Hotel-Information) - [B&S Creekside Retreat Lodging](https://expedia.ca/Holden-Hotels-BS-Creekside-Retreat-Lodging.h118137129.Hotel-Information) - [Cozy A-Frame cabin right next to the water.](https://expedia.ca/La-Cygne-Hotels-Cozy-A-Frame-Cabin-Right-Next-To-The-Water.h78428194.Hotel-Information) - [Romantic Country Cabin at Lakeview by Sue](https://expedia.ca/Romantic-Country-Cabin-With-A-Lake-View.h75032980.Hotel-Information) - [Relaxing 2-Bedroom Cottage Retreat-Beautiful Views & Great Amenities-Sleeps 6](https://expedia.ca/La-Cygne-Hotels-Relaxing-2-Bedroom-Cottage-Retreat-Beautiful-Views-Great-Amenities-Sleeps-6.h117361976.Hotel-Information) - [Peaceful Garden City Getaway w/ Grill & Fire Pit](https://expedia.ca/Garden-City-Hotels-Peaceful-Garden-City-Getaway-W-Grill-Fire-Pit.h105702478.Hotel-Information) - [4-bedroom Spacious Loft just 17 minutes from Overland Park](https://expedia.ca/Louisburg-Hotels-Top-Floor-Of-Historic-Building-Transformed-Into-Spacious-Loft.h88937572.Hotel-Information) - [Private 3 Acre Bungalow](https://expedia.ca/Louisburg-Hotels-Private-3-Acre-Bungalow.h70964791.Hotel-Information) - [Countryside Vacation Rental in Paola!](https://expedia.ca/Countryside-Vacation-Rental-Retreat.h93589140.Hotel-Information) - [Family Friendly Lake House -1 hour from KC!](https://expedia.ca/La-Cygne-Hotels-Family-Friendly-Lake-House-1-Hour-From-KC.h82882309.Hotel-Information) - [Spacious 5-bedroom house with AC, WiFi in tranquil Butler. Right outside of town](https://expedia.ca/Butler-Hotels-Spacious-5-Bedroom-House-With-AC.h116183870.Hotel-Information) - [Relaxing retreat with beautiful view. Fireplace, grill, firepit, and kayaks.](https://expedia.ca/La-Cygne-Hotels-Quiet.h96662365.Hotel-Information) - [Cute Family Cabin at Lakeview by Sue](https://expedia.ca/Cute-Family-Cabin-With-A-Lake-View-And-Quiet-Country-Charm.h75033858.Hotel-Information) - [Cozy Family lake house](https://expedia.ca/La-Cygne-Hotels-Cozy-Family-Lake-House.h78398952.Hotel-Information) - [A peaceful oasis w breathtaking views. This home is truly one-of-a-kind!](https://expedia.ca/Drexel-Hotels-A-Tranquil-Mini-Lodge-Settled-Near-Water-On-The-Outskirts-Of-A-Ranch-In-SouthKC.h95749964.Hotel-Information) - [Super 8 by Wyndham Butler](https://expedia.ca/Butler-Hotels-Super-8-By-Wyndham-Butler.h856019.Hotel-Information) - [Rural Drexel Cabin on 30 Acres: Unplug + Unwind!](https://expedia.ca/Drexel-Hotels-Rural-Drexel-Cabin-On-30-Acres-Unplug-Unwind.h101277142.Hotel-Information) - [Relax in a Fully Loaded RV Stay](https://expedia.ca/Archie-Hotels-Relax-In-A-Fully-Loaded-RV-Stay.h116664699.Hotel-Information) [See a list of all hotels in Adrian](https://expedia.ca/All-Adrian-Hotels.d3000421349.Travel-Guide-City-All-Hotels) ### More ways to book - [Book 5 Star Hotels in Adrian on Expedia.com](https://www.expedia.com/5Star-Adrian-Hotels.s50-0-d3000421349.Travel-Guide-Filter-Hotels) ### Expedia's Latest Trends Hotels - [Hotels in Niagara Falls](https://expedia.ca/Niagara-Falls-Hotels.d602721.Travel-Guide-Hotels) - [Hotels in Honolulu](https://expedia.ca/Honolulu-Hotels.d1488.Travel-Guide-Hotels) - [Hotels in Bangor](https://expedia.ca/Bangor-Hotels.d6050918.Travel-Guide-Hotels) - [Hotels in Minot](https://expedia.ca/Minot-Hotels.d2392.Travel-Guide-Hotels) - [Hotels in Grand Forks](https://expedia.ca/Grand-Forks-Hotels.d1312.Travel-Guide-Hotels) - [Hotels in Kalispell](https://expedia.ca/Kalispell-Hotels.d6056415.Travel-Guide-Hotels) - [Hotels in Burlington](https://expedia.ca/Burlington-Hotels.d601763.Travel-Guide-Hotels) - [Hotels in Fargo](https://expedia.ca/Fargo-Hotels.d6059376.Travel-Guide-Hotels) - [Hotels in Palm Springs](https://expedia.ca/Palm-Springs-Hotels.d180676.Travel-Guide-Hotels) - [Hotels in Branson](https://expedia.ca/Branson-Hotels.d6058734.Travel-Guide-Hotels) - [Hotels in Myrtle Beach](https://expedia.ca/Myrtle-Beach-Hotels.d601685.Travel-Guide-Hotels) Flights - [Cheap Flights to Myrtle Beach](https://expedia.ca/Cheap-Flights-To-Myrtle-Beach.d601685.Travel-Guide-Flights) - [Cheap Flights to Cuba](https://expedia.ca/Cheap-Flights-To-Cuba.d6499.Travel-Guide-Flights) - [Cheap Flights to Columbia](https://expedia.ca/Cheap-Flights-To-Columbia.d901.Travel-Guide-Flights) - [Cheap Flights to Springfield](https://expedia.ca/Cheap-Flights-To-Springfield.d602962.Travel-Guide-Flights) - [Cheap Flights to Palm Springs](https://expedia.ca/Cheap-Flights-To-Palm-Springs.d180676.Travel-Guide-Flights) - [Cheap Flights to Branson](https://expedia.ca/Cheap-Flights-To-Branson.d6058734.Travel-Guide-Flights) - [Cheap Flights to Anaheim](https://expedia.ca/Cheap-Flights-To-Anaheim.d5921.Travel-Guide-Flights) Cars - [Car rentals in Springfield](https://expedia.ca/Car-Rentals-In-Springfield.d602962.Car-Rental-Guide) - [Car rentals in Palm Springs](https://expedia.ca/Car-Rentals-In-Palm-Springs.d180676.Car-Rental-Guide) Activities - [Things to do in Honolulu](https://expedia.ca/Things-To-Do-In-Honolulu.d1488.Travel-Guide-Activities) - [Things to do in Branson](https://expedia.ca/Things-To-Do-In-Branson.d6058734.Travel-Guide-Activities) Packages - [Disney Vacations](https://expedia.ca/Disney.d3000453867.Destination-Travel-Guides) - [Branson Vacations](https://expedia.ca/Branson.d6058734.Destination-Travel-Guides) - [Honolulu Vacations](https://expedia.ca/Honolulu.d1488.Destination-Travel-Guides) - [Central Vacations](https://expedia.ca/Central.d10503.Destination-Travel-Guides) - [Canadian Vacations](https://expedia.ca/Canadian.d6127256.Destination-Travel-Guides) General - [Visit Jefferson City](https://expedia.ca/Jefferson-City.dx8072) - [Visit Osage Beach](https://expedia.ca/Osage-Beach.dx6058781) - [Visit Plattsburg](https://expedia.ca/Plattsburg.dx3000445416) ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Adrian? > The amount you pay for a 5-star hotel in Adrian can vary depending on the time of year you travel and how long you plan to stay, among other factors. Take advantage of our price per night filter and other search tools to land the best rate on a luxurious stay. > > > > - Search for the lowest price per night ### What makes a hotel 5 stars in Adrian? > Impeccable guest service is at the heart of every 5-star hotel in Adrian. From the minute you arrive, staff ensure your every need is met, whether arranging customized tours or providing in-room massages. What's more, hotels have to feature top-rate conveniences to be entitled to a 5-star rating. These can include deluxe baths, spas or saunas, pools, gastronomic kitchens and knowledgeable concierge. ### Are there any 5-star all-inclusive resorts in Adrian? > Our filters are the easiest way to search for exactly what you want. Check the "All inclusive" and "5-star" boxes to show the most luxurious resorts in Adrian where your meals, lodging, entertainment and activities are included in the upfront price. At these getaways, your vacation is pure leisure from the moment you check in. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)