A modern glass building with a curved facade and a sign reading "The Kentucky Center".

4 Stars Hotels in Southern Indiana, United States of America from CA $143

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Check availability on Southern Indiana 4 Star Hotels

Next weekend
Nov 6 - Nov 8
In two weeks
Nov 13 - Nov 15

Our top choices for Southern Indiana 4-star hotels

A balcony with a view of a river, a bridge, and a cityscape.

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,441 reviews)
"Great place to stay!!!"
United States
Shun
The price is CA $190
CA $224 total
includes taxes & fees
Nov 22 - Nov 23
Galt House Hotel Trademark Collection by Wyndham
A grand lobby with ornate columns, plush seating, and a chandelier.

2. The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,448 reviews)
"We had a nice stay!"
United States
katisha
The price is CA $146
CA $172 total
includes taxes & fees
Nov 25 - Nov 26
The Brown Hotel
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

3. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (2,210 reviews)
"Beautiful Hotel"
United States
Kristan
The price is CA $284
CA $334 total
includes taxes & fees
Nov 16 - Nov 17
Omni Louisville Hotel
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.

4. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,002 reviews)
"Great place"
United States
MILTON
The price is CA $234
CA $276 total
includes taxes & fees
Nov 22 - Nov 23
Louisville Marriott Downtown
A spacious lobby with a central escalator, seating areas, and modern lighting.

5. Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,000 reviews)
"amazing location will definitely be back"
United States
Michael Jered
The price is CA $203
CA $238 total
includes taxes & fees
Nov 26 - Nov 27
Hyatt Regency Louisville
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

6. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,385 reviews)
"Great room, excellent staff, exceptional breakfast, very clean."
United States
Chase
The price is CA $182
CA $214 total
includes taxes & fees
Nov 24 - Nov 25
Embassy Suites Louisville Downtown
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

7. The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,001 reviews)
"I really enjoyed my stay and hope to return soon."
United States
Donna
The price is CA $210
CA $247 total
includes taxes & fees
Nov 30 - Dec 1
The Grady
A classical gold statue in front of a multi-story building with large windows and a brick facade.

8. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,002 reviews)
"Nice modern rooms and excellent cocktails in the bar."
United States
Erick
The price is CA $213
CA $257 total
includes taxes & fees
Nov 23 - Nov 24
21c Museum Hotel Louisville
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

9. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (514 reviews)
"Very clean / helpful and accommodating staff / excellent restaurant"
United States
Kimberly
The price is CA $282
CA $331 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Distil, Autograph Collection
An outdoor dining area with a long table and wicker chairs, overhead lighting, and a view of the city.

10. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,084 reviews)
"We’ve stayed here a number of times and we love it. Right in the middle of NuLu, it’s the perfect spot."
United States
Jesse
The price is CA $222
CA $261 total
includes taxes & fees
Nov 15 - Nov 16
Hotel Genevieve part of JdV by Hyatt
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (169 reviews)
"Great location for whiskey row! Everyone was so and we wish we’d have had another night!! Highly recommend!"
United States
Adrienne Tremonti
The price is CA $182
CA $214 total
includes taxes & fees
Nov 24 - Nov 25
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A modern building with a prominent sculpture in front, large glass windows, and a brightly lit entrance.

12. DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
4.0 star property
Downtown Evansville
8.4 out of 10, Very good, (1,001 reviews)
"Check- in was super easy and seamless, even more so with the early check-in. The receptionist was very nice and helpful giving us information on places to visit; welcome cookies are so yummy. Such a great start to the stay!"
United States
Aleli Rodriguez
The price is CA $141
CA $163 total
includes taxes & fees
Nov 8 - Nov 9
DoubleTree by Hilton Evansville
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.

13. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,002 reviews)
"Very good hotel, a lot of history on it"
United States
Leonardo
The price is CA $199
CA $234 total
includes taxes & fees
Nov 26 - Nov 27
Seelbach Hilton Louisville Downtown
A modern building with a sign reading "Stellar Suites" and a crescent moon logo.

14. Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (157 reviews)
"Location was great near meant restaurants and nightspots"
United States
Kevin
The price is CA $160
CA $259 total
includes taxes & fees
Dec 1 - Dec 2
Stellar Suites
A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.

15. The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (740 reviews)
"Wonderful and unique property with an outstanding breakfast."
United States
David
The price is CA $126
CA $143 total
includes taxes & fees
Nov 3 - Nov 4
The Pepin Mansion Historic B&B
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a high-rise building with balconies.

16. CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
7.6 out of 10, Good, (36 reviews)
"We love staying at this location when we come to Louisville. It’s a great apartment that is conveniently located. Love the view of the Big Four Bridge at night!"
United States
Jennifer
The price is CA $131
CA $315 total
includes taxes & fees
Nov 5 - Nov 6
CozySuites at Nulu
A modern hotel with a 'Stay Apt Suites' sign, featuring a brick facade, large windows, and a parking lot.

17. stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (59 reviews)
"Great option for a long term stay, good area many businesses in walking distance!"
Canada
Darlene
stayAPT Suites Louisville North-Clarksville
A modern lounge with leather sofas, a coffee table, and a view of a classical building.

18. The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (8 reviews)
"The room was great and clean. Great location. "
United States
De'Carlon
The Reserve on Main
A large, red brick Victorian-style building with a prominent tower, a flag, and a well-maintained front yard.

19. Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
4.0 star property
Old Louisville
10.0 out of 10, Exceptional, (5 reviews)
"Inn Keepers were wonderful. "
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
A modern kitchen with wooden cabinets, a black microwave, and a stainless steel refrigerator.

20. Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10 reviews)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
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Learn more about Southern Indiana

Live music, casinos, and sights from Patoka Lake Swimming Beach to Patoka Lake—discover it all in Southern Indiana.

See all hotels in Southern Indiana
A riverboat with multiple decks and passengers, docked near a bridge.

Top Southern Indiana Hotel Reviews

DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville

10/10 Excellent
"It was a very clean & comfortable stay . And enjoyed the restaurant & bar while we were there . Would definitely stay again ."
SueAnn 1-night trip
Posted 1 day ago
DoubleTree by Hilton Evansville

Find out more about Southern Indiana

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Southern Indiana are calling your name. Known for providing first-rate service in amazing locations, each of the Southern Indiana 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Southern Indiana. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Southern Indiana, United States of America, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Southern Indiana hotels with 4 Stars provide everything you need to unwind in style.

Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
You'll discover a variety of 4-star hotels in Southern Indiana, including in Louisville. Galt House Hotel Trademark Collection by Wyndham is a customer favourite in this city that offers beauty services and massage services. Another stay that rates highly with travellers is Hotel Distil, Autograph Collection. A rooftop terrace and proposal/romance packages help make it their number one choice.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
Expedia can help you easily find the perfect 4-star hotel for your stay in Southern Indiana. Use our handy filter tool to fine-tune your search by things like amenities, budget and star rating and get access to awesome deals in a few clicks.

  • Search for the lowest price from CA $143

What's the difference between 5-star and 4-star hotels in Southern Indiana?
Offering an inviting traveller experience and upmarket surroundings, 4-star hotels are a great option for your Southern Indiana escape. These types of stays generally feature lots of useful amenities that make it simple to unpack and unwind — think 24-hour room service, pools and gyms. Or enjoy even more lavishness at a 5-star hotel designed to spoil you with exclusive perks and amenities. Full-service health clubs, premium toiletries and gourmet dining are typically featured at these plush retreats.