Title: 4 Stars Hotels in Santa Fe, Alachua from CA $141 - Find Cheap Santa Fe Hotels With 4 Stars | Expedia.ca [Santa Fe Travel Guide](https://expedia.ca/Santa-Fe.dx553248635975870004)[Hotels in Santa Fe](https://expedia.ca/Santa-Fe-Hotels.d553248635975870004.Travel-Guide-Hotels)[Vacation Rentals in Santa Fe](https://expedia.ca/Santa-Fe-Vacation-Rentals.d553248635975870004.Travel-Guide-VacationRentals)[Flights to Santa Fe](https://expedia.ca/Cheap-Flights-To-Santa-Fe.d553248635975870004.Travel-Guide-Flights)[Santa Fe Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Fe.d553248635975870004.Car-Rental-Guide)[Santa Fe Vacation Packages](https://expedia.ca/Santa-Fe.d553248635975870004.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 4 Stars Hotels in Santa Fe, Alachua from CA $141 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Fe 4 Star Hotels Tonight [Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=553248635975870004&startDate=2025-11-04&endDate=2025-11-05&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 5 - Nov 6](https://www.expedia.ca/Hotel-Search?regionId=553248635975870004&startDate=2025-11-05&endDate=2025-11-06&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635975870004&startDate=2025-11-07&endDate=2025-11-09&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635975870004&startDate=2025-11-14&endDate=2025-11-16&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Santa Fe 4 Star Hotels ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/ff7eaa86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/d3e89f45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/65f39696.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/d4e32e3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Gainesville Gainesville 7.6/10 Good (1007) "Great hotel for it’s class" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Stephen CA $125 CA $141 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Gainesville-Hotels-DoubleTree-By-Hilton-Gainesville.h49617.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/112000000/111070000/111068900/111068878/fde9d20d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111070000/111068900/111068878/43e50acf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/112000000/111070000/111068900/111068878/cd46f9ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (QueenBed) | Private kitchen](https://images.trvl-media.com/lodging/112000000/111070000/111068900/111068878/f1c72573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Landing Apartments Newberry Newberry 10/10 Exceptional (42) "Enjoyed our stay! We were there for a softball tournament and they were very close to the fields. Very clean and the beds were comfortable. Apartment had everything we needed for our quick trip. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tabitha [](https://www.expedia.ca/Newberry-Hotels-Barsala-At-The-Vanguard-Apartments.h111068878.Hotel-Information) ![Luxury Apartment | In-room dining](https://images.trvl-media.com/lodging/113000000/112030000/112021600/112021506/83b7eb2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/113000000/112030000/112021600/112021506/a6158955.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Living area](https://images.trvl-media.com/lodging/113000000/112030000/112021600/112021506/f5d3840f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112030000/112021600/112021506/56376f80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Two Bedroom Two Bathroom Apartment with Balcony by The Scholar Gainesville 8.4/10 Very good (7) "The unit was located in the perfect are, there was so much to do around within 10 minutes driving distance. The unit was was spacious and comfortable we felt like home." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) NANCY CA $150 CA $366 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Gainesville-Hotels-The-Scholar.h112021506.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Santa-Fe-Hotels.s40-0-d553248635975870004.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Santa-Fe-Hotels.s40-0-d553248635975870004.Travel-Guide-Filter-Hotels) ## Top Santa Fe Hotel Reviews ![DoubleTree by Hilton Gainesville](//images.trvl-media.com/lodging/1000000/50000/49700/49617/ff7eaa86_y.jpg) ### DoubleTree by Hilton Gainesville 10/10 Excellent "The bathroom towels smell funny , only that be noted but the rest perfect thanks " [](https://expedia.ca/Gainesville-Hotels-DoubleTree-By-Hilton-Gainesville.h49617.Hotel-Information) ## Find out more about Santa Fe If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Santa Fe are calling your name. Known for providing first-rate service in amazing locations, each of the Santa Fe 4 Stars hotels lets discerning travelers bask in an unforgettable experience. Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day. It’s all waiting for you at the top four star hotels in Santa Fe. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Santa Fe, Alachua, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Santa Fe hotels with 4 Stars provide everything you need to unwind in style. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [1 Star Hotels in Hogan's Creek](https://www.expedia.ca/1Star-Hogans-Creek-Jacksonville-Hotels.s10-n553248635976479246-0.Travel-Guide-Filter-Hotels) - [1 Star Hotels in Northeast Florida](https://www.expedia.ca/1Star-Northeast-Florida-Hotels.s10-0-d6047863.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Middleburg](https://www.expedia.ca/2Star-Middleburg-Hotels.s20-0-d183107.Travel-Guide-Filter-Hotels) - [3 Star Hotels in De La Vista](https://www.expedia.ca/3Star-De-La-Vista-Lady-Lake-Hotels.s30-n553248635976471956-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Grandin](https://www.expedia.ca/3Star-Grandin-Hotels.s30-0-d553248635975871409.Travel-Guide-Filter-Hotels) - [3 Star Hotels in The Villages](https://www.expedia.ca/3Star-The-Villages-Hotels.s30-0-d6053731.Travel-Guide-Filter-Hotels) - 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