A dry grassland with a few trees, a red building, and mountains in the background.

4 Stars Hotels in Pickens, South Carolina from CA $143

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Check availability on Pickens 4 Star Hotels

Tonight
Oct 18 - Oct 19
Tomorrow
Oct 19 - Oct 20
Next weekend
Oct 23 - Oct 25
In two weeks
Oct 30 - Nov 1

Our top choices for Pickens 4-star hotels

A modern bathroom with a large mirror, a marble sink, and a towel rack.
A modern interior with a fireplace, plush seating, and a stone accent wall.
A modern interior with a stone fireplace, seating areas, and a unique ceiling design.
A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
Greenville Downtown
United States
colleen
CA $495
CA $561 total
includes taxes & fees
Nov 15 - Nov 16
Grand Bohemian Lodge Greenville, Autograph Collection
A hotel facade with arched windows, a fountain, and a sign for "The Westin."
A banquet hall with round tables, chandeliers, and ornate windows.
A lobby with patterned flooring, a grand staircase, and elegant furniture.
Meeting facility

2. The Westin Poinsett Greenville

The Westin Poinsett Greenville
Greenville Downtown
United States
Karen
CA $239
CA $275 total
includes taxes & fees
Nov 1 - Nov 2
The Westin Poinsett Greenville
A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.
A modern kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a granite countertop. There are three white bar stools and two pendant lights.
A bedroom with a bed, bedside tables, a ceiling fan, and two windows with blinds.
A modern kitchen with white cabinets, a stainless steel refrigerator, and a bar area with white stools.

3. Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
Greenville Downtown
United States
Michelle
CA $178
CA $196 total
includes taxes & fees
Oct 29 - Oct 30
Mint House Greenville Downtown by Kasa
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.
A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.
A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.

4. The Abernathy of Clemson

The Abernathy of Clemson
Clemson
United States
Amy
CA $212
CA $235 total
includes taxes & fees
Nov 17 - Nov 18
The Abernathy of Clemson
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
A modern bar area with a wooden ceiling, green bar stools, and a bar counter.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.

5. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
United States
Laurrie
CA $263
CA $292 total
includes taxes & fees
Nov 8 - Nov 9
The Shepherd Hotel Downtown Clemson
A white, two-story house with a front porch, surrounded by trees and shrubs.
A hallway with a wooden bench, a chair, a cabinet, and a painting on the wall.
A two-story building with a white exterior, a front door, and a balcony.
A bedroom with two beds, a TV, and a fireplace.

6. Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
Pendleton
United States
Christine
CA $129
CA $143 total
includes taxes & fees
Oct 20 - Oct 21
Liberty Hall Bed and Breakfast
A modern building with outdoor seating and a garden.
A row of modern, two-story buildings with a covered patio area.
A two-story house with a dark roof and siding, a front porch with four yellow chairs, and a well-maintained garden with shrubs and mulch.
A modern living room with a sofa, coffee table, and dining table. There is a TV mounted on the wall, a coffee machine, and a bookshelf.

7. The Station by Compo Hotels

The Station by Compo Hotels
Travelers Rest
United States
Anonymous traveller
CA $339
CA $489 total
includes taxes & fees
Nov 8 - Nov 9
The Station by Compo Hotels
Terrace/patio
Private kitchen
Private kitchen
A bedroom with a bed, bedside tables, a desk, and a chair. There is a window with a view of greenery outside.

8. Tuxedo Falls

Tuxedo Falls
Zirconia
United States
Mary Jane
Tuxedo Falls
A two-story house with a tiled roof, a stone fire pit, and outdoor seating.
A restaurant with a stone fireplace, hanging crystal chandelier, and multiple dining tables set with white tablecloths and wine glasses.
A spacious room with wooden beams, a large chandelier, and a cozy seating area with orange chairs and a white sofa.
A bar with a large window view of mountains and a chandelier.

9. Hotel Domestique

Hotel Domestique
Travelers Rest
United States
Chuck
CA $593
CA $652 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Domestique
A wooden interior with a hot tub and a pool.
A modern living room with a blue sofa, a wooden side table with a lamp, a ceiling fan, a fireplace, and a large window with blinds.
A wooden deck with wicker furniture and a sign that says "EXPLORE".
A cozy balcony with wicker furniture, a green lantern, and a sign that says "EXPLORE".

10. Sapphire Valley Condo w/ Pool & Lake Beach Access!

Sapphire Valley Condo w/ Pool & Lake Beach Access!
Cashiers
Sapphire Valley Condo w/ Pool & Lake Beach Access!
A spacious living room with a large window, a grey sofa, a coffee table, and a dining area with chairs.
A spacious dining area with a wooden table and chairs, a chandelier, and large windows offering views of the outdoors.
A modern kitchen with white cabinets, a wooden dining table, and a chandelier.
A living room with a sectional sofa, a coffee table, and a rug. There are two windows with a view of trees.

11. Sapphire Home w/ Grill & Pool Access

Sapphire Home w/ Grill & Pool Access
Sapphire
United States
William
Sapphire Home w/ Grill & Pool Access
A wooden gazebo with a roof, surrounded by trees, overlooking a lake.
A cozy living room with a fireplace, leather armchair, and a large window.
A modern kitchen with stainless steel appliances, a granite countertop, and large windows offering a view of the outdoors.
A marina with boats docked, a lifeguard station, and a dock with lounge chairs.

12. Designer Retreat w/ Pool, Golf + Beach Access!

Designer Retreat w/ Pool, Golf + Beach Access!
Salem
United States
Anonymous traveller
Designer Retreat w/ Pool, Golf + Beach Access!
An indoor swimming pool with clear lanes, a covered roof, and a bench area.
Interior
Interior
A two-story yellow house with a front porch, a small garden, and a pathway leading to the entrance.

13. Wooded Keowee Key Retreat Near Golf & Trails

Wooded Keowee Key Retreat Near Golf & Trails
Salem
Wooded Keowee Key Retreat Near Golf & Trails
A large indoor swimming pool with a wooden interior, surrounded by large windows offering views of the outdoors.
A lakeside cabin with a covered picnic area and a row of beach chairs along the shore.
A building with a blue roof, wooden exterior, and a porch with a wooden railing.
A bedroom with a large bed, two bedside tables, a wooden headboard, and a sliding glass door leading to a balcony.

14. Sunny Sapphire Townhome w/ Resort Amenities!

Sunny Sapphire Townhome w/ Resort Amenities!
Sapphire
Sunny Sapphire Townhome w/ Resort Amenities!
A spacious dining area with a wooden table and chairs, a fireplace, and large windows offering a view of the outdoors.
A backyard with a fire pit, four Adirondack chairs, a wooden shed, and a small wooden structure with a smiley face.
A two-story house with a covered porch and a front yard.
A spacious dining area with a wooden table and chairs, a large rug, and a view of the kitchen and outdoor area.

15. Lake Hartwell Frank Howard Home Clemson

Lake Hartwell Frank Howard Home Clemson
Anderson
Lake Hartwell Frank Howard Home Clemson
Interior
A kitchen with white cabinets, a stainless steel refrigerator, a microwave, and a sink.
A multi-story hotel with a parking lot and a view of a lake.
A marina with boats docked, a wooden pier, and a clear sky.

16. Lake Keowee Condo w/ Balcony & Resort Amenities!

Lake Keowee Condo w/ Balcony & Resort Amenities!
Salem
United States
Kathleen
Lake Keowee Condo w/ Balcony & Resort Amenities!
A marina with boats docked, a lifeguard station, and a dock with lounge chairs.
An indoor swimming pool with clear lanes, a covered roof, and a bench area.
A spacious dining area with a wooden table, chairs, and a chandelier. A cozy seating area with a sofa and chairs is visible in the background.
A multi-story hotel with a parking lot and a view of a lake.

17. Lake Keowee Condo: Resort Pools & Lake Access!

Lake Keowee Condo: Resort Pools & Lake Access!
Salem
United States
Shawn
Lake Keowee Condo: Resort Pools & Lake Access!
A gazebo with a wooden roof and open sides, surrounded by trees and overlooking a body of water.
A spacious living room with a fireplace, a television, and a staircase leading to an upper level.
A marina with boats docked, surrounded by greenery and trees.
A swimming pool with a view of a lake and docked boats.

18. Salem Vacation Rental w/ Lake Keowee Access!

Salem Vacation Rental w/ Lake Keowee Access!
Salem
Salem Vacation Rental w/ Lake Keowee Access!
A gazebo with a wooden roof and open sides, surrounded by trees and overlooking a body of water.
A sandy beach with a calm lake surrounded by trees.
An aerial view of a residential area with houses, a golf course, and a lake in the background.
A marina with boats docked, a lifeguard station, and a view of a lake surrounded by trees.

19. Views, Pools & Marina: Lake Keowee Condo!

Views, Pools & Marina: Lake Keowee Condo!
Salem
Views, Pools & Marina: Lake Keowee Condo!
A wooden gazebo with a roof and a table and chairs inside, surrounded by trees and overlooking a lake.
A spacious hotel lobby with a bar area, seating arrangements, and large windows offering views.
A modern living room with a sofa, a coffee table, and a fireplace.
A modern building with a prominent wooden entrance canopy, stone pillars, and a clear sky.

20. Tee Times & Lake Days! Luxe Keowee Key Living

Tee Times & Lake Days! Luxe Keowee Key Living
Salem
Tee Times & Lake Days! Luxe Keowee Key Living
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Learn more about Pickens

Nestled in the foothills of the Blue Ridge Mountains, this charming town offers a slice of small-town Americana. Hike the trails at Table Rock State Park, then explore the Hagood Mill Historic Site to experience local heritage and traditional bluegrass music.

See all hotels in Pickens
A calm lake reflecting a forested mountain range with autumn foliage.

Top Pickens Hotel Reviews

Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa

10/10 Excellent
"Great location, convenient!"
Michelle 1-night trip
Posted 9 hours ago
Mint House Greenville Downtown by Kasa

Find out more about Pickens

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Pickens are calling your name. Known for providing first-rate service in amazing locations, each of the Pickens 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Pickens. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Pickens, South Carolina, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Pickens hotels with 4 Stars provide everything you need to unwind in style.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Pickens?
To lock in a 4-star hotel in Pickens that's within your budget, take advantage of Expedia's handy search filters. Browse the availability during your travel dates and use our pricing filter to set your maximum rate. You can also list your results by the most wallet-friendly option first.
  • Search for the lowest price from CA $143
What's the difference between 5-star and 4-star hotels in Pickens?
If you choose to stay at a 4-star hotel in Pickens, you'll usually find plenty of conveniences to make sure you're comfortable, such as a gym, restaurant and pool. You can look forward to excellent service and upmarket accommodations. Go for a 5-star hotel and you'll get a few extra perks — think on-site spas, around-the-clock concierge and indulgent turndown services. You'll most likely get extra amenities and first-rate services at a 5-star stay, but both are fabulous options for luxury travellers.
Does Pickens have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your next dream escape in Pickens where just about everything is taken care of, from your room to your food, activities and entertainment. We can also help you find standard 4-star stays in and around this sought-after destination.

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