"If your goal is ease of walking around the Plaka neighborhood, Syntagma Square/Parliament, and the Acropolis, Nefeli is an excellent choice. Great central location near everything you want but just off the tourist streets, in a quieter neighborhood. (Tricky access by car, however!)
Rooms were basic and comfortable. Price was great, considering the fantastic location. Other hotels in the neighborhood are all $40+ more expensive. There is a parking garage a few buildings away; street parking...