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Mountain Hotels in Southern Minnesota

The Plaza Hotel & Suites Winona

1025 Highway 61 E Winona MN

2 hours drive from Mayo Clinic

Stay at this hotel in Winona. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions ...

8.8/10 Excellent! (1,000 reviews)

Great location for everything you want to do in Winona from hiking to eagles to museums. Great visit.

Reviewed on Mar 11, 2026

Holiday Inn Express & Suites Winona by IHG

1128 Homer Rd Winona MN

2 hours drive from Mayo Clinic

Book a stay at this family-friendly hotel in Winona. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful staff in ...

9.2/10 Wonderful! (914 reviews)

Nice room, breakfast had many choices!

Reviewed on Mar 29, 2026

See all 1,194 properties in Southern Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.