Title: Luxury Vacations in South America 2026 | Expedia.ca ![](https://images.trvl-media.com/place/6140917/ba4ee8aa-2da1-4310-8a44-1015fb6e7a3d.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # South America Luxury Vacations ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Flight and Luxury hotel deals in South America Price found within the past 48 hours. Click for updated prices. ![Bastión Luxury Hotel](https://images.trvl-media.com/lodging/9000000/8270000/8268200/8268158/c291524c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Bastión Luxury Hotel Cartagena Walled City CA $679 per person Apr 22 - Apr 25 found 1 day ago Roundtrip flight included Fort Lauderdale (FLL) to Cartagena (CTG) 9.6/10 Exceptional! (1,001 reviews) Staff were friendly & very helpful. The room was excellent with a great bed & shower. We stayed for one night at the end of our week in Cartagena Reviewed on Feb 14, 2026 ![Hotel Boutique Casa del Coliseo](https://images.trvl-media.com/lodging/8000000/7230000/7229300/7229274/6f60c628_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Boutique Casa del Coliseo Cartagena Walled City CA $781 per person Apr 22 - Apr 25 found 1 day ago Roundtrip flight included Fort Lauderdale (FLL) to Cartagena (CTG) 9.4/10 Exceptional! (303 reviews) Lovely, stylish hotel that felt like home for 4 nights. Great location in the middle of Cartagena’s action, coolly converted house with a wonderful lounge. Very comfortable bedroom and bathroom. Nice rooftop pool and loungers. And it didn’t feel at all corporate or formulaic. Nice friendly staff and decent breakfast. No bar but they’ll bring you a drink in the lounge or on the balcony. Recommended by a fussy, style-conscious traveller! Reviewed on Feb 6, 2026 ![The Charlee Hotel](https://images.trvl-media.com/lodging/5000000/4130000/4129400/4129341/232f02be_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Charlee Hotel El Poblado CA $1,536 per person Mar 20 - Mar 27 found 1 day ago Roundtrip non-stop flight included Toronto (YTO) to Medellín (MDE) 8.8/10 Excellent! (1,002 reviews) Simplemente lo mejor Reviewed on Feb 10, 2026 ![Charleston Santa Teresa Cartagena](https://images.trvl-media.com/lodging/1000000/890000/889900/889840/60f4ae0e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Charleston Santa Teresa Cartagena Cartagena Walled City CA $926 per person Apr 22 - Apr 25 found 1 day ago Roundtrip flight included Fort Lauderdale (FLL) to Cartagena (CTG) 9.4/10 Exceptional! (765 reviews) Great Staff. Helpful Concierge. Spotless room. Beautiful hotel. Awesome pool. Nice breakfast. Loved this place and am ready to visit again. Reviewed on Feb 10, 2026 ![Ananda Hotel Boutique](https://images.trvl-media.com/lodging/3000000/2650000/2645700/2645670/2ed2aa61_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Ananda Hotel Boutique Cartagena Walled City CA $778 per person Apr 22 - Apr 25 found 1 day ago Roundtrip flight included Fort Lauderdale (FLL) to Cartagena (CTG) 9.2/10 Wonderful! (422 reviews) Beautiful hotel in the historic center. You can walk everywhere. The Hotel staff are very friendly and provide excellent service. The rooms are clean, large and very confortable. The breakfasts are very delicious. \\they have a very nice pool and a terrace with a beautiful view of the city. Nice place to take a drink and admire the the sunset. I would recommend this hotel. Reviewed on Feb 6, 2026 Don't see what you're looking for? See all available trips from Columbus to South America [View all trips](https://expedia.ca/go/package/search/FlightHotel/2026-03-18/2026-03-25/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=null&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 5\* Luxury holidays in South America Price found within the past 48 hours. Click for updated prices. ![Charleston Santa Teresa Cartagena](https://images.trvl-media.com/lodging/1000000/890000/889900/889840/60f4ae0e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Charleston Santa Teresa Cartagena Cartagena Walled City CA $926 per person Apr 22 - Apr 25 found 1 day ago Roundtrip flight included Fort Lauderdale (FLL) to Cartagena (CTG) 9.4/10 Exceptional! (765 reviews) Great Staff. Helpful Concierge. Spotless room. Beautiful hotel. Awesome pool. Nice breakfast. Loved this place and am ready to visit again. Reviewed on Feb 10, 2026 ![The Charlee Hotel](https://images.trvl-media.com/lodging/5000000/4130000/4129400/4129341/232f02be_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Charlee Hotel El Poblado CA $1,536 per person Mar 20 - Mar 27 found 1 day ago Roundtrip non-stop flight included Toronto (YTO) to Medellín (MDE) 8.8/10 Excellent! (1,002 reviews) Simplemente lo mejor Reviewed on Feb 10, 2026 ![Sofitel Bogota Victoria Regia](https://images.trvl-media.com/lodging/1000000/20000/14500/14472/0d6b720f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Sofitel Bogota Victoria Regia Zona T CA $1,473 per person Apr 21 - Apr 28 found 1 day ago Roundtrip flight included Montreal (YMQ) to Bogotá (BOG) 9.4/10 Exceptional! (900 reviews) Out of this world! Best in class, clean and best service. Location A+++++ Reviewed on Jan 28, 2026 Don't see what you're looking for? See all available trips from Columbus to South America [View all trips](https://expedia.ca/go/package/search/FlightHotel/2026-03-18/2026-03-25/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=null&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 3 Night Luxury holidays in South America Price found within the past 48 hours. Click for updated prices. ![Bastión Luxury Hotel](https://images.trvl-media.com/lodging/9000000/8270000/8268200/8268158/c291524c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Bastión Luxury Hotel Cartagena Walled City CA $679 per person Apr 22 - Apr 25 found 1 day ago Roundtrip flight included Fort Lauderdale (FLL) to Cartagena (CTG) 9.6/10 Exceptional! (1,001 reviews) Staff were friendly & very helpful. The room was excellent with a great bed & shower. We stayed for one night at the end of our week in Cartagena Reviewed on Feb 14, 2026 ![Hotel Boutique Casa del Coliseo](https://images.trvl-media.com/lodging/8000000/7230000/7229300/7229274/6f60c628_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Boutique Casa del Coliseo Cartagena Walled City CA $781 per person Apr 22 - Apr 25 found 1 day ago Roundtrip flight included Fort Lauderdale (FLL) to Cartagena (CTG) 9.4/10 Exceptional! (303 reviews) Lovely, stylish hotel that felt like home for 4 nights. Great location in the middle of Cartagena’s action, coolly converted house with a wonderful lounge. Very comfortable bedroom and bathroom. Nice rooftop pool and loungers. And it didn’t feel at all corporate or formulaic. Nice friendly staff and decent breakfast. No bar but they’ll bring you a drink in the lounge or on the balcony. Recommended by a fussy, style-conscious traveller! Reviewed on Feb 6, 2026 ![Charleston Santa Teresa Cartagena](https://images.trvl-media.com/lodging/1000000/890000/889900/889840/60f4ae0e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Charleston Santa Teresa Cartagena Cartagena Walled City CA $926 per person Apr 22 - Apr 25 found 1 day ago Roundtrip flight included Fort Lauderdale (FLL) to Cartagena (CTG) 9.4/10 Exceptional! (765 reviews) Great Staff. Helpful Concierge. Spotless room. Beautiful hotel. Awesome pool. Nice breakfast. Loved this place and am ready to visit again. Reviewed on Feb 10, 2026 Don't see what you're looking for? See all available trips from Columbus to South America [View all trips](https://expedia.ca/go/package/search/FlightHotel/2026-03-18/2026-03-25/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=null&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 4 Night Luxury holidays in South America Price found within the past 48 hours. Click for updated prices. ![Bastión Luxury Hotel](https://images.trvl-media.com/lodging/9000000/8270000/8268200/8268158/c291524c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Bastión Luxury Hotel Cartagena Walled City CA $662 per person May 12 - May 16 found 1 day ago Roundtrip flight included Bogotá (BOG) to Cartagena (CTG) 9.6/10 Exceptional! (1,001 reviews) Staff were friendly & very helpful. The room was excellent with a great bed & shower. We stayed for one night at the end of our week in Cartagena Reviewed on Feb 14, 2026 ![Hotel Boutique Casa del Coliseo](https://images.trvl-media.com/lodging/8000000/7230000/7229300/7229274/6f60c628_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Boutique Casa del Coliseo Cartagena Walled City CA $719 per person May 12 - May 16 found 1 day ago Roundtrip flight included Bogotá (BOG) to Cartagena (CTG) 9.4/10 Exceptional! (303 reviews) Lovely, stylish hotel that felt like home for 4 nights. Great location in the middle of Cartagena’s action, coolly converted house with a wonderful lounge. Very comfortable bedroom and bathroom. Nice rooftop pool and loungers. And it didn’t feel at all corporate or formulaic. Nice friendly staff and decent breakfast. No bar but they’ll bring you a drink in the lounge or on the balcony. Recommended by a fussy, style-conscious traveller! Reviewed on Feb 6, 2026 ![Charleston Santa Teresa Cartagena](https://images.trvl-media.com/lodging/1000000/890000/889900/889840/60f4ae0e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Charleston Santa Teresa Cartagena Cartagena Walled City CA $897 per person May 12 - May 16 found 1 day ago Roundtrip flight included Bogotá (BOG) to Cartagena (CTG) 9.4/10 Exceptional! (765 reviews) Great Staff. Helpful Concierge. Spotless room. Beautiful hotel. Awesome pool. Nice breakfast. Loved this place and am ready to visit again. Reviewed on Feb 10, 2026 Don't see what you're looking for? See all available trips from Columbus to South America [View all trips](https://expedia.ca/go/package/search/FlightHotel/2026-03-18/2026-03-25/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=null&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=THVAD_SPRING_PROMO_6023117) ## Plan the perfect luxury South America vacation with Expedia #### What are some benefits when booking luxury South America vacations? When you book a luxury South America vacation, you get to enjoy some of the best amenities and special features available. Luxury vacation options often feature spa facilities right in your accommodation, along with room service and an on-site restaurant. The quality of the bedding and even the water pressure tends to be better, so it's the perfect solution for travellers looking to put their feet up and relax. #### How can I find all-inclusive luxury vacations in South America? If you're looking for something luxurious in South America, all you have to do is take advantage of our search filters. You can implement a filter to only show 5-star accommodations as well as some amenities you may be interested in, like spa facilities and hot tubs. When you opt for an all-inclusive package, you can enjoy luxury alongside a potential discount for booking your accommodation and flight together. #### Can I book a cheap luxury vacation? While luxury vacations tend to be on the more costly end of the spectrum, ranging from CA $662, there are a few methods you can try to lower the price as much as possible. When booking a flight and accommodation together, you can enjoy savings of up to 41\. After implementing filters for luxury features, you can also sort by price to list the cheapest luxury packages first. #### Are there luxury spa vacations? Yes, luxury spa vacations are available and quite popular in South America. When you book one of these experiences, it's easier than ever to relax, unwind and recharge in between excursions. Either way, you can easily find spa vacations by implementing the spa filter in your search. #### What should I look for in a luxury family vacation in South America? When booking something for the whole family, it's important to consider exactly what kind of experience your family will want.Luxury packages make it easy to keep everyone happy with creature comforts. Kids especially enjoy features like pools, a delicious breakfast and plenty of space. Suites tend to offer your family members a bit more privacy and comfort compared to simple rooms throughout South America. #### Can I book last-minute luxury vacations? Yes, last-minute bookings are often available in South America. All you have to do is enter your travel dates to see what's available. Sometimes, you'll even find additional discounts for booking last-minute, as accommodations are desperate to fill their last remaining spaces. #### What can help me find the best luxury vacation deals in South America? You can use a few strategies to find the best deals on luxury vacation packages. Consider travelling during the off-season to take advantage of the typically lower overall prices. Additionally, staying in the less popular parts of South America or travelling to more obscure destinations altogether can often lead to lower prices. #### Can I book a luxury vacation that is fully refundable? Yes, fully refundable reservations are sometimes available on luxury vacation packages in South America. You can implement a filter for it specifically or check out the policy section on any one of your search results. It should clearly state what's necessary to qualify for a fully refundable booking. #### Why should I book my luxury vacation with Expedia? When you book with Expedia, you can enjoy a one-stop shop for all your travel planning needs. We offer accommodations as well as flights, and you may even be able to enjoy discounts by booking them together. Of course, Expedia Rewards members will find even more discounts and earn points that can be put toward discounts on future bookings. ## Luxury Hotels in South America ![Hotel das Cataratas, A Belmond Hotel, Iguassu Falls](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/7373d519_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel das Cataratas, A Belmond Hotel, Iguassu Falls Rodovia Br 469 Km 32 Foz do Iguaçu PR CA $1,078 CA $1,248 total Mar 16 - Mar 17 includes taxes & fees Book a stay at this luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property ... 9.8/10 Exceptional! (1,001 reviews) Superb stay! This was a “White Lotus” caliber experience for the two of us. Service was amazing, needs were anticipated and seamlessly addressed. Location in the park was a total nature immersion experience. Absolutely loved it! Reviewed on Feb 14, 2026 [](https://expedia.ca/Foz-Do-Iguacu-Hotels-Hotel-Das-Cataratas.h53288.Hotel-Information) ![Hotel Club Frances](https://images.trvl-media.com/lodging/5000000/4920000/4914500/4914467/f4102dc9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Club Frances Rodríguez Peña 1832 Buenos Aires Capital Federal CA $295 CA $299 total Feb 19 - Feb 20 Book a stay at this luxury hotel in Buenos Aires. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. ... 9.4/10 Exceptional! (648 reviews) The staff was extremely accommodating and the room was lovely. Reviewed on Feb 14, 2026 [](https://expedia.ca/Buenos-Aires-Hotels-Hotel-Club-Frances.h4914467.Hotel-Information) ![Palacio del Inka, A Luxury Collection Hotel by Marriott](https://images.trvl-media.com/lodging/1000000/520000/519400/519319/bd303ee6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Palacio del Inka, A Luxury Collection Hotel by Marriott Plazoleta Santo Domingo No 259 Cusco Cusco CA $413 CA $511 total Mar 3 - Mar 4 Book a stay at this luxury hotel in Cusco. Enjoy a full-service spa, room service, and a fitness center. Our guests praise the helpful staff in our reviews. ... 9.4/10 Exceptional! (985 reviews) Palacio del Inka, A Luxury Collection Hotel by Marriott in Cusco is a fantastic place to stay. The location is perfect within walking distance of the main attractions, making it easy to explore the city. The hotel is beautiful, very clean, and full of character. The staff are incredibly friendly ... Reviewed on Feb 11, 2026 [](https://expedia.ca/Cusco-Hotels-Palacio-Del-Inka.h519319.Hotel-Information) [See all 118,358 properties in South America](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6023117) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## More Vacations Ideas [South America Flights ](https://expedia.ca/Destinations-In-South-America.d6023117.Flight-Destinations)[ South America Hotels ](https://expedia.ca/Destinations-In-South-America.d6023117.Hotel-Destinations)[ South America Vacation Rentals ](https://expedia.ca/Destinations-In-South-America.d6023117.Vacation-Rental-Destinations)[ South America Car Rentals ](https://expedia.ca/Destinations-In-South-America.d6023117.Car-Rental-Destinations)[ South America Vacations ](https://expedia.ca/South-America.d6023117.Destination-Travel-Guides) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app